Abstract: Methods, computing devices, and MRI systems that reduce artifacts produced by Maxwell gradient terms in TSE imaging using non-rectilinear trajectories are disclosed. With this technology, a RF excitation pulse is generated to produce transverse magnetization that generates a NMR signal and a series of RF refocusing pulses to produce a corresponding series of NMR spin-echo signals. An original encoding gradient waveform comprising a non-rectilinear trajectory is modified by adjusting a portion of the original encoding gradient waveform or introducing a zero zeroth-moment waveform segment at end(s) of the original encoding gradient waveform. During an interval adjacent to each of the series of RF refocusing pulses a first gradient pulse is generated. At least one of the first gradient pulses is generated according to the modified gradient waveform. An image is constructed from generated digitized samples of the NMR spin-echo signals obtained.
Type:
Application
Filed:
April 28, 2022
Publication date:
November 10, 2022
Applicant:
University of Virginia Patent Foundation
Inventors:
John P. Mugler, III, Craig H. Meyer, Adrienne Campbell, Rajiv Ramasawmy, Josef Pfeuffer
Abstract: A method of transforming a degree of freedom (DoF) in a multiple sensorial media (mulsemedia) system includes detecting, by a motion detector, a motion of an object to which motion effects are to be provided; calculating, by a motion proxy calculator, a motion proxy corresponding to the motion of the object; and transforming, by a transformer, the motion proxy into a motion command implementable within a motion range of a motion platform.
Type:
Application
Filed:
March 25, 2022
Publication date:
November 10, 2022
Applicant:
POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
Inventors:
Seung Moon CHOI, Gyeo Re YUN, Sang Yoon HAN
Abstract: A virtual reality game- and biosignal sensor-based VOR assessment and rehabilitation apparatus includes: a biosignal sensing unit which senses and notifies of head movement and eye movement of a patient using an eye tracker and an inertial measurement unit (IMU) sensor attached or installed to a head-mounted display device; a VOR function assessment unit which configures and provides a game for VOR function assessment; a patient-personalization control unit which determines, on the basis of the VOR gain of the patient, the types and order of rehabilitation games, and a rehabilitation level; and a rehabilitation game providing unit which configures and provides games for at least one among smooth pursuit, saccades, VOR rehabilitation exercise, amplified VOR rehabilitation exercise, and suppressive VOR rehabilitation exercise, and determines the difficulty levels of the games on the basis of the rehabilitation level.
Type:
Application
Filed:
June 25, 2020
Publication date:
November 10, 2022
Applicant:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Abstract: Disclosed is a mobile terminal and method for controlling the same. According to an embodiment of the disclosure, a mobile terminal includes a display; a sensing unit; and a controller, wherein the display is configured to display a virtual keyboard and display a content entered by a user using the virtual keyboard on a content input window, wherein the virtual keyboard includes an undo key for canceling a task performed in the content input window and a redo key for restoring a canceled task, and wherein when the sensing unit detects a first drag past a first border line designated on a side of the undo key after a touch on the undo key, the controller is configured to display a first expected change of content expected to be changed and displayed in the content input window to be identified when one of tasks performed in the content input window is to be canceled in a designated unit.
Type:
Application
Filed:
October 15, 2020
Publication date:
November 10, 2022
Applicant:
Kookmin University Industry Academy Cooperation Foundation
Inventors:
Tao LUO, Yichieh LEE, Haoyue GUO, Zhouxiong JIN, Jinghong NAN, Erica PELLEGATTA, Wonheung JO, Ayoung HWANG, Yaejin KANG
Abstract: This document provides methods and materials for treating hypocapnia. For example, methods and materials for delivering CO2 to a mammal to treat hypocapnia or compensate for a reduced level of CO2 are provided.
Type:
Application
Filed:
July 25, 2022
Publication date:
November 10, 2022
Applicant:
Mayo Foundation for Medical Education and Research
Inventors:
Jan Stepanek, Michael J. Cevette, Gaurav N. Pradhan, Samantha J. Kleindienst, Jamie M. Bogle, Rebecca S. Blue, Karen K. Breznak
Abstract: The present invention relates to extracellular vesicles derived from ginger (Zingiber officinale) and a use thereof, and provides: extracellular vesicles which are derived from ginger and have anticancer activity, a pharmaceutical composition and a health functional food composition which is for preventing or treating cancer and contains the extracellular vesicles as an active ingredient. The ginger-derived extracellular vesicles can penetrate into cancer cells, have excellent anticancer activity, such as inhibiting the proliferation, infiltration and migration of cancer cells, and thus may be provided as an effective anticancer composition.
Type:
Application
Filed:
September 25, 2020
Publication date:
November 10, 2022
Applicants:
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, ANDONG NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors:
Moon-Chang BAEK, Young-Eun CHO, Dong Ha KIM
Abstract: A composition of matter comprising a fusion protein attached to the outer surface of a substrate is disclosed. The fusion protein comprises a light-generating protein and a light-transducing protein. Uses of the composition of matter are disclosed.
Type:
Application
Filed:
May 5, 2022
Publication date:
November 10, 2022
Applicant:
Technion Research & Development Foundation Limited
Abstract: Proposed is a Geumhwagyu extract as an active ingredient. The Geumhwagyu extract of the present disclosure inhibits the differentiation of pre-adipocytes by inducing the degradation of CEBP-? and inhibits the expression of CEBP-?, PPAR?, Perilipin-1, Adiponectin, FABP4, etc., to suppress the accumulation of lipids in adipocytes. It can be easily used as a composition for preventing or managing obesity by inhibiting it and lowering the content of TG (Triacylglycerol) to show anti-obesity activity.
Type:
Application
Filed:
January 17, 2022
Publication date:
November 10, 2022
Applicant:
Andong National University Industry-Academic Cooperation Foundation
Abstract: The present invention relates to: a biomarker composition for diagnosing or predicting the prognosis of thyroid cancer, comprising a preparation capable of detecting a mutation in a PLEKHS1 promoter gene; and a use thereof. The biomarker composition for diagnosing or predicting the prognosis of thyroid cancer of the present invention confirms whether a mutation is present in a PLEKHS1 promoter gene, and thus can provide information needed for diagnosing metastatic (distant metastatic) differentiated thyroid cancer, and also confirms whether a mutation is present in BRAF, TERT promoter, three types of RAS and a TP53 gene in addition to the PLEKHS1 promoter gene, and thus, with respect to radioactive iodine therapy response and survival, can classify the prognosis of a metastatic differentiated thyroid cancer patient into one of three prognosis groups, and predict the same.
Type:
Application
Filed:
October 23, 2020
Publication date:
November 10, 2022
Applicant:
THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors:
Chan Kwon JUNG, Seung Hyun JUNG, Yeun Jun CHUNG
Abstract: Disclosed herein are an optimal range of salivary MMP-9 (matrix metalloproteinase-9) protein concentrations which allows for screening the risk of periodontitis, a method of its application for screening the risk of periodontitis using this range, the methods each comprising the steps: of measuring a concentration of MMP-9 protein in saliva taken from a subject; and establishing an optimal range of salivary MMP-9 concentrations which allows for screening the risk of periodontitis. Utilizing saliva taken in a non-invasive manner from a subject, the methods make it convenient to screen periodontitis. In addition, the methods have the effect of quickly and accurate determining the risk of periodontitis by measuring a concentration of MMP-9 protein present in a trace amount in saliva and enable periodontitis to be easily determined in clinics and at home.
Type:
Application
Filed:
May 3, 2022
Publication date:
November 10, 2022
Applicant:
Seoul National University R&DB Foundation
Abstract: An apparatus and a method for caring emotion of a driver based on a vehicle sound, may include a detector configured to detect driving information of the vehicle and body information of a user, a non-transitory storage to store instructions, and a processor to execute the instructions. The processor determines an emotional status of the driver by use of at least one of the driving information or the body information, to generate a healing sound by designing a virtual sound based on the driving information and the emotional status of the driver, and to generate and output the healing sound.
Type:
Application
Filed:
October 27, 2021
Publication date:
November 10, 2022
Applicants:
HYUNDAI MOTOR COMPANY, Kia Corporation, Seoul National University R&DB Foundation
Inventors:
Ki Chang KIM, Eun Soo JO, Tae Kun YUN, Sang Jin HONG, Dong Chul PARK, Kyoung Jin CHANG, Ju In KIM, Jin Sung LEE, Myung Hwan YUN, Sung Ho KIM
Abstract: Provided is photo-sintering nano ink. The photo-sintering nano ink includes a photo-sintering precursor including a conductive nano particle and an oxide film surrounding the conductive nano particle, polymer binder resin, and an adhesive.
Type:
Application
Filed:
July 27, 2022
Publication date:
November 10, 2022
Applicant:
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)
Abstract: Provided is an apparatus and method for obtaining a vulnerable transaction sequence. A vulnerable transaction sequence obtaining apparatus may include a storage configured to transitorily or non-transitorily store at least one program; and a processor configured to receive the at least one program, to select a vulnerable transaction sequence candidate in the at least one program using a cost function, to obtain a verification condition by performing symbolic execution over the transaction sequence candidate, and to check whether the verification condition is satisfiable when the vulnerable transaction sequence is unfound as a verification result about the verification condition, and to determine the vulnerable transaction sequence candidate as the vulnerable transaction sequence when the verification condition is satisfiable.
Type:
Application
Filed:
April 6, 2021
Publication date:
November 10, 2022
Applicant:
Korea University Research and Business Foundation
Abstract: Provided herein are immunogenic compositions that may be used, in some aspects, to induce an immune response against an Ehrlichia such as Ehrlichia cams. In some embodiments, the immunogenic composition comprises an E. canis bacterin and/or adjuvant, such as for example an emulsion or liposomal adjuvant. Related methods such as for diagnosis of or vaccination against ehrlichiosis are also provided.
Type:
Application
Filed:
July 13, 2020
Publication date:
November 10, 2022
Applicants:
Research Development Foundation, Zoetis Services LLC
Inventors:
Jere W. McBRIDE, Paul J. DOMINOWSKI, Suman MAHAN, Jason J. MILLERSHIP, Duncan M. MWANGI, Sharath RAI, Sharon M. WAPPEL
Abstract: Disclosed is a photovoltaic module including a transparent material layer, and a plurality of solar cells disposed inside one side of the transparent material layer, and at least one of the plurality of solar cells is disposed to be perpendicular to one side surface of the transparent material layer.
Type:
Application
Filed:
July 25, 2022
Publication date:
November 10, 2022
Applicant:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Inventors:
Donghwan KIM, Yoonmook KANG, Yongseok JUN, Hae-Seok LEE, Yujin JUNG, Jongwon KO
Abstract: A nucleic acid amplification method using a solid-phase carrier according to the present invention comprises: capturing a target nucleic acid comprising mRNA on a solid-phase carrier; carrying out complementary-strand synthesis on the solid phase; carrying out exonuclease treatment to degrade and remove unreacted target- capturing nucleic acid on the solid phase; and then carrying out mRNA degradation and homopolymer addition by TdT reaction in the presence of a chain-terminating nucleotide triphosphate. According to the method of the present invention, cDNA can be stably and highly efficiently amplified even from a small amount of sample even in cases where the ratio of the amount of enzyme to the DNA substrate on the solid phase is excessive, where the reaction time is excessive, and/or where reagents show lot-to-lot variation.
Abstract: A cloaking apparatus and method are disclosed herein. The cloaking apparatus for cloaking a target object using meta-material includes a compensation unit, and a cloaking cell. The compensation unit is disposed in a second space surrounding part of a first space including the target object, and is composed of a first meta-material having a predetermined negative refractive index. The cloaking shell is configured to surround part of the compensation unit, and is composed of a second meta-material. The negative refractive index may be a negative refractive index that is adapted to cloak the target object by compensating for the positive refractive index of the first space.
Type:
Grant
Filed:
May 13, 2020
Date of Patent:
November 8, 2022
Assignee:
Univ. of Seoul Industry Cooperation Foundation
Abstract: Methods for prophylactically treating a stress-induced affective disorder or stress-induced psychopathology in a subject are provided. Also provided are methods for inducing and/or enhancing stress resilience in a subject. In certain embodiments, an effective amount of (R,S)-ketamine or (2R, 6R)-hydroxynorketamine ((2R, 6R)-HNK) is administered to a female or male subject prior to a stressor.
Type:
Grant
Filed:
November 9, 2018
Date of Patent:
November 8, 2022
Assignees:
The Trustees of Columbia University in the City of New York, The Research Foundation for Mental Hygiene, Inc.
Inventors:
Christine Ann Denny, Briana Kaying Chen
Abstract: The present invention relates to a catalyst precursor for forming a molybdenum disulfide catalyst through a reaction with sulfur in heavy oil and to a method for hydrocracking heavy oil by using same. According to the present invention, the yield of a low-boiling liquid product with a high economic value in the products by heavy oil cracking can be increased, and the yield of a relatively uneconomical gas product or coke (toluene insoluble component), which is a byproduct, can be significantly lowered.
Type:
Grant
Filed:
June 27, 2019
Date of Patent:
November 8, 2022
Assignees:
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION OF SUNCHON NATIONAL UNIVERSITY
Inventors:
Sunyoung Park, Chul Wee Lee, Gyoo Tae Kim, Hwi Min Seo, Minehul Chung, Seok Hwan Son, Byong Min Choi
Abstract: A piezoelectric structure is disclosed which includes a single crystal having piezoelectric coefficients d31 and d32 of opposite magnitude, such that when an alternating electric field is applied in the Z direction, the piezoelectric structure expands in one of the X and Y directions and contracts in the other of the X and Y direction, a first electrode coupled to the single crystal, and a second electrode coupled to the single crystal, wherein the alternating electric field is input to the single crystal through the first and second electrodes.