Abstract: Provided are a compound of chemical formula 1 or 2 and a use thereof. The compound can be advantageously used in the prevention or treatment of metabolic diseases including type 2 diabetes, insulin resistance, or obesity, on the basis of a mechanism of autophagy activation through the promotion of lysosome production.

Abstract: Systems and methods for treating or manipulating biological tissues are provided. In the systems and methods, a biological tissue is placed in contact with an array of electrodes. Electrical pulses are then applied between a bias voltage bus and a reference voltage bus of a distributor having switching elements associated with each of the electrodes. The switching elements provide a first contact position for coupling electrodes to bias voltage bus, a second contact position for coupling electrodes to the reference voltage bus, and a third contact position for isolating electrodes from the high and reference voltage buses. The switching elements are operated over various time intervals to provide the first contact position for first electrodes, a second contact position for second electrodes adjacent to the first electrodes, and a third contact position for a remainder of the electrodes adjacent to the first and second electrodes.

Abstract: A membrane is provided that includes a membrane substrate defining a plurality of pores to allow ion transport therethrough; an ion-doped conductive polymer disposed on a surface of the membrane substrate; and a conductive material disposed between the membrane substrate and the ion-doped conductive polymer. The membrane may have an areal density from about 0.01 Coulombs per cm2 (C/cm2) to about 100 C/cm2. Such membranes provide for controlled bidirectional ion transport therethrough and may be used in electrochemical cells that includes such membranes as part of (or the entirety of) the separator. Such separators may be used to control charge transfer through the electrochemical cell and/or reversibly stop charge transfer therethrough to prevent thermal runaway.

Abstract: The present invention provides a thermoelectric micro-supercapacitor integrated device comprising: a thermoelectric power generation module comprising a thermoelectric unit body including a thermoelectric channel interposed between two different heat sources and disposed on a substrate, the thermoelectric channel being composed of an n-type or p-type semiconductor; and a micro-supercapacitor module configured to be operated in cooperation with the thermoelectric power generation module and including a pair of collector electrodes between which an electric potential difference is generated through the thermoelectric channel.

Abstract: The present invention relates to a structure for fastening composite structures, and more particularly, to a sewing machine for stitching composite materials which is capable of automatically and continuously stitching the composite structures by using a high-rigidity fiber in order to laminate and join the composite materials. The sewing machine for stitching composite materials according to the present invention automatically and continuously performs a stitching operation for joining composite materials by using a high-rigidity composite fiber for joining the composite materials, and as a result, it is possible to reduce process time for joining the composite materials and improve productivity.

Abstract: A neural device to which a conditioned response function is imparted and a driving method thereof are disclosed. Quantum dots and a polymer insulating layer are formed between upper and lower electrodes. Conductive filaments are formed at interfaces between the quantum dots and the polymer insulating layer. When a positive pulse, which is an unconditioned stimulus signal, is applied, the conductive filaments are formed, and a low resistance state is implemented. As the number of applications of a negative pulse, which is a conditioned stimulus signal, increases, the neural device is switched from a high resistance state to the low resistance state. Through this, the neural device having learning ability for the conditioned stimulus signal may be implemented and driven.

Abstract: Provided herein are compositions and methods for packaging a recombinant adeno-associated virus (rAAV) particle comprising using inverted terminal repeats (ITRs) and rep genes of different serotypes and/or using chimeric rep genes.

Abstract: A distributed control system includes a plurality of control units that controls respective units of a plurality of devices, and a communication network that includes a communication line that connects the control units. A control unit of each of the devices is configured to determine a state target value, according to consensus control of a multi-agent system, by using a current state index value of a self-device, and a difference between a latest state index value of an adjacent device received from a control unit of the adjacent device, and a latest state index value of the self-device received from the control unit of the adjacent device.

Abstract: A method for encoding image signal, according to the present invention, can: encode a partial block coefficient flag indicating whether a coefficient of a current partial block is a non-zero coefficient; encode a first flag indicating whether an absolute value of the coefficient is greater than 1, encode a second flag indicating whether the absolute value of the coefficient is greater than 2; encode the residual coefficients, which have not been encoded, on the basis of the first flag or the second flag in the current partial block; and encode a code for the coefficient of the current partial block.

Abstract: A method of depositing a film comprising a monolayer of particles. The method includes providing a dispersion comprising particles and at least two liquids and depositing drops of the dispersion onto a substrate and evaporating the at least two liquids resulting in a film of a monolayer of the particles. One embodiment of the method includes a coating on the outer surface of particles such that the coating makes the particles substantially non-dispersible, substantially non-soluble and substantially non-suspendable in one of the liquids. A particulate film containing at least one layer of particles, wherein the at least one layer is substantially made of particles of a chemical composition and has uniform thickness. Optical devices containing a particulate film containing at least one layer of particles, wherein the at least one layer is substantially made of particles of a chemical composition and has uniform thickness.

Abstract: A mapping method for identifying density which includes determining at least one geographical boundary about a geographical location of interest, the at least one geographical boundary is free of any self-intersections, dividing the at least one geographical boundary into a plurality of regions of interests, each region of interest is defined by a start point and an end point on the at least one geographical boundary, wherein the end point associated with one region of interest coincides with a start point of a neighboring region of interest wherein the region of interest falls within the at least one geographical boundary, for each of the plurality of regions of interest, calculating at least one parameter of interest within the region of interest, and graphically presenting a segment between the start point and the end point on the at least one geographical boundary with a line thickness proportional to the calculation results.

Abstract: This document relates to methods and materials for treating polycystic kidney disease (PKD) and/or a complication associated with a PKD (e.g., a cardiovascular complication). For example, one or more betaines (e.g., trimethylglycine) can be administered to a mammal having, or at risk of developing, a PKD to treat the mammal.

Abstract: An image signal decoding method according to the present invention comprises the steps of: decoding information indicating whether a current block is encoded using a multi-mode intra prediction; when it is determined that the current block is encoded in the multi-mode intra prediction, dividing the current block into a plurality of partial blocks; and obtaining an intra prediction mode of each of the plurality of partial blocks.

Abstract: An image signal decoding method according to the present invention comprises the steps of: decoding information indicating whether a current block is encoded using a multi-mode intra prediction; when it is determined that the current block is encoded in the multi-mode intra prediction, dividing the current block into a plurality of partial blocks; and obtaining an intra prediction mode of each of the plurality of partial blocks.

Abstract: An antenna apparatus includes a patch antenna pattern; a first feed via to feed power to the patch antenna pattern in a non-contact manner on a first side of the patch antenna pattern; and a plurality of feed patterns disposed on the first side of the patch antenna pattern on different levels and overlapping each other, and including at least one feed pattern that is electrically connected to the first feed via, and each having a width greater than a width of the first feed via and a cross-sectional area smaller than a cross-sectional area of the patch antenna pattern.

Abstract: A system includes a plurality of control devices that respectively control the states of a plurality of apparatuses and are connected to each other via communication lines. When each of the control devices determines a state target value of its own apparatus using the current state indicator value of the own apparatus, and the distributed controller input which is a function of the state indicator value of an apparatus adjacent to the own apparatus and the state indicator value of the own apparatus, the control gain which adjusts contribution of the distributed controller input to the state target value is determined based on a communication delay time between the control devices.

Abstract: Disclosed herein are compositions of rAAV particles and methods for administrating rAAV particles having enhanced transduction properties.

Abstract: The present invention relates to a modified siloxane resin, a crosslinked modified siloxane resin, and a method for preparing the crosslinked resin. More specifically, the present invention relates to a modified siloxane resin, a crosslinked modified siloxane resin with excellent superhydrophobicity obtained by dual curing of the resin, and a method for preparing the crosslinked resin. The use of the modified siloxane resin according to the present invention allows the crosslinked modified siloxane resin to have excellent superhydrophobicity and high hardness. The water repellency of the crosslinked resin can be appropriately controlled by varying the amount of the siloxane resin mixed.

Abstract: A method for preparing a light sensitive particle that uses at least one metal precursor material and at least one dopant precursor material mixed in solution absent a surfactant. Upon an optional adjustment of pH to about 3 to about 6, a light-sensitive particle comprising a metal-dopant material may be formed and separated from the solution. The light-sensitive particle may comprise a Q-dot particle. Also described are the particles themselves.

Abstract: A system and method is provided for creating motion-adjusted or motion-compensated images of a patient to guide an interventional medical procedure. The method includes displaying a static roadmap and a plurality of dynamic images to show the interventional medical device aligned on the static roadmap using a motion transformation. Alignment of the interventional medical device on the static roadmap is based on a user selection of one of motion compensation of the interventional medical device relative to the static roadmap to produce a plurality of images that do not show patient motion or motion adjustment of the static roadmap relative to the interventional medical device to produce a plurality of images that show patient motion.