Abstract: The present invention relates to a modified siloxane resin, a crosslinked modified siloxane resin, and a method for preparing the crosslinked resin. More specifically, the present invention relates to a modified siloxane resin, a crosslinked modified siloxane resin with excellent superhydrophobicity obtained by dual curing of the resin, and a method for preparing the crosslinked resin. The use of the modified siloxane resin according to the present invention allows the crosslinked modified siloxane resin to have excellent superhydrophobicity and high hardness. The water repellency of the crosslinked resin can be appropriately controlled by varying the amount of the siloxane resin mixed.

Abstract: Disclosed herein are compositions of rAAV particles and methods for administrating rAAV particles having enhanced transduction properties.

Abstract: Disclosed herein are circular zymogens of RNase 1 that have a proteolytic cleavage site and are activated by a specific protease. These circular zymogens are useful for treatment of disorders that are characterized by a specific protease (e.g., HIV-1 protease).

Abstract: A semiconductor switch includes four diodes, two transistors, and a capacitor. The capacitor includes a fourth terminal and a fifth terminal. An anode of a third diode is connected to a third terminal of a first transistor. A cathode of the third diode is connected to a first terminal of the first transistor and to an anode of a first diode. An anode of a fourth diode is connected to a third terminal of a second transistor. A cathode of the fourth diode is connected to a first terminal of the second transistor and to an anode of the second diode. A cathode of the first diode is connected to a cathode of the second diode and to the fourth terminal of the capacitor. An anode of the third diode is connected to the anode of the fourth diode and to the fifth terminal of the capacitor.

Abstract: An apparatus, method, and system for post-processing a printed graphene ink pattern or other deposition on a substrate. A pulsed UV laser is tunable between various energy densities to selectively modify the printed ink or deposition in electrical or physical properties. In one example, radical improvements in electrical conductivity are achieved. In another example, controlled transformation from essentially 2D printed or deposited graphene to surface topology of 3D nanostructures are achieved. The 3D structures are beneficial in such applications as electrochemical sensors of different types and characteristics. In another example, hydrophobicity of the printed or deposited graphene can be manipulated starting from a hydrophilic to super hydrophobic surface.

Abstract: Immunogenic compositions and methods of using them include a biodegradable or bioerodible polyanhydride nanoparticle comprising 1,8-bis(p-carboxyphenoxy)-3,6-dioxaoctane (CPTEG) and 1,6-bis(p-carboxyphenoxy)hexane (CPH) copolymers, an immunogenic protein of an Influenza Virus and an adjuvant entrapped within an interior of the nanoparticle, and an excipient. The immunogenic composition may be administered to a subject to confer both local and systemic immunity to the Influenza Virus.

Abstract: The present disclosure provides methods and systems for identifying biologically active random peptides (BARPs) in prokaryotic cells, such as bacterial cells, and libraries of transformed bacterial cells, where each cell/colony expresses a different candidate BARP.

Abstract: Described herein are compounds of the formula (I)-(III) (or a pharmaceutically acceptable salt, polymorph, prodrug, solvate or clathrate thereof), as well as methods of making and using compounds of the formula (I)-(III) to, among other things, treat various forms of cancer.

Abstract: The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). A method of operating a receiving terminal in a wireless communication system may include: transmitting, to a transmitting terminal, information on capabilities of the receiving terminal in relation to an independent component analysis (ICA) technique; receiving, from the transmitting terminal, a signal generated based on the capabilities; and decoding the signal using the ICA technique in consideration of the amount of change in the channel for the signal.

Abstract: An image sensor is provided, the image sensor comprising a plurality of photo-diode pixels arranged in a two-dimensional array, an energy harvesting output bus connected to the plurality of photo-diode pixels, an image sensing output bus connected to the plurality of photo-diode pixels, and a plurality of switching buses connected to the plurality of photo-diode pixels to direct an output of a varying percentage of the plurality of photo-diode pixels to either the energy harvesting output bus or the image sensing output bus.

Abstract: A power semiconductor device includes a silicon carbide substrate and at least a first layer or region formed above the substrate. The silicon carbide substrate has a pattern of pits formed thereon. The device includes a stop layer that is disposed at least in part laterally between the pits. The device further comprising an ohmic metal disposed at least in the pits to form low-resistance ohmic contacts, wherein the ohmic metal contacts at least parts of the stop layer.

Abstract: A machine drive includes a suspension force inverter, a torque inverter, and a capacitor. The suspension force inverter provides suspension force electrical signals to suspension force electrical terminals. Each suspension force electrical terminal connects to a suspension coil of a stator winding. Each suspension force electrical signal provides a phase to a single suspension force electrical terminal. A single stator winding is associated with each phase. The torque inverter provides torque electrical signals to torque electrical terminals. Each torque electrical signal provides the phase to a single torque electrical terminal. Each torque electrical terminal connects to both the suspension coil and a torque coil of the single stator winding of the associated phase. The capacitor connected in parallel across the suspension force inverter. The torque inverter is connected to a voltage source. The capacitor is connected to the voltage source through the torque invertor and the suspension force inverter.

Abstract: The invention provides anelastase inhibitor for use in the promotion of muscle regeneration in the treatment of a myopathy, as well as a method for promoting muscle regeneration in a subject with a myopathy, the method comprising providing the subject with a therapeutically effective amount of an elastase inhibitor. Further provided is a pharmaceutical composition comprising anelastase inhibitor for use in the promotion of muscle regeneration in the treatment of a myopathy. Elastase inhibitors may have a protective effect on muscle progenitor cells and their regenerative potential, which aids muscle cell regeneration. By protecting regenerative potential of muscle progenitor cells, elastase inhibitors enable or enhance the grown of new or existing muscle fibres.

Abstract: Compounds, pharmaceutical formulations, and methods of treating bacterial infections are disclosed.

Abstract: Methods, systems, and compositions to produce high resolution, highly scalable patterns on a variety of substrates. A high resolution sacrificial negative of the desired pattern in inkjet printed on the substrate with an inkjet printable ink. A viscous solution is coated or deposited over the negative pattern and substrate. The solution is stabilized such as by drying and adheres to the substrate. The sacrificial negative is removed, leaving the dried solution in the high resolution form factor defined by the removed negative. This allows the solution to be formulated without regard to meeting inkjet printing requirements but results in a high resolution final positive pattern on the substrate.

Abstract: Disclosed herein are peptide inhibitors of AniA. Pharmaceutical compositions are also disclosed that include one or more peptide inhibitors of AniA and/or nucleic acids encoding the same. The pharmacological inhibition of AniA should disable anaerobic respiration and augment the ability of existing antimicrobials to clear the pathogen. Thus, also disclosed are methods of inhibiting and/or treating infection from N. gonorrhoeae.

Abstract: In embodiments described herein, a light emitting diode device comprises an emission device with an emission region and a bottom contact layer. The emission region comprises n cascading emission layers, where n is a whole and positive number. The n cascading emission layers comprise at least one superlattice structure. In an embodiment, a tunnel junction is spaced between a first superlattice structure and a second superlattice structure. In an embodiment, light extraction is enhanced with a trapezoidal shaped chip, a roughened exit interface, and encapsulation of the chip with a hemispherical shaped polymer. In an embodiment, the superlattice structure may be repeated periods of InAs/AlGaInSb. In another embodiment, the superlattice may be repeated periods of InAs/GaInSb/InAs/AlAsSb. In another embodiment, between the bottom contact layer and the emission region is a tunnel junction where the bottom contact layer and the tunnel junction form an n-type anode layer.

Abstract: The present disclosure generally relates to a process to prepare a cell culture system that mimics the structure of blood brain barrier (BBB) and are useful to study the functions thereof. In particular, the present invention relates to a direct-contact coculture and triculture systems prepared by plating BMECs on a pre-formed lawn of coculture of astrocytes and pericytes on the apical surface of a culture-chamber to achieve a truly direct contact triculture model for BBB. The cell culture systems disclosed herein are also useful for studying the functions of the blood brain barrier and predicting the efficacy and potential toxicity of a drug candidate.

Abstract: An apparatus for trapping and sensing nanoparticles using plasmonic nanopores, comprising a conductive transparent layer, a conductive film layer mounted to a substrate, the film layer comprising a plurality of nanopores for trapping nanoparticles contained in a fluid situated between the conductive transparent layer and the conductive film layer, and an electric field source connected between the transparent layer and the film layer.

Abstract: The present disclosure relates to an indoor device-free human counting method and a system for the method. The present disclosure may estimate the number of humans present on a radio link accurately based on an amount of attenuation of a received radio signal and an amount of change of the received radio signal over time.