Patents Assigned to Foundation
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Patent number: 10874630Abstract: A method for reducing macrophage migration inhibitory factor (MIF or MMIF) cytokine or its biological activity, including the step of administering an isothiocyanate functional surfactant to a patient having a disease or condition wherein MIF cytokine or its biological activity is implicated in the disease or condition.Type: GrantFiled: March 10, 2020Date of Patent: December 29, 2020Assignee: The William M. Yarbrough FoundationInventor: Michael E. Silver
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Patent number: 10875895Abstract: The present disclosure relates to novel antibacterial cell-penetrating peptides and derivatives, and methods to make and use the novel antibacterial cell-penetrating peptides and derivatives. The novel antibacterial cell-penetrating peptides of the present invention with shorter linker between a pyrrolidine ring and a guanidine group provide unexpectedly higher potency against a broader scope of bacterial.Type: GrantFiled: November 13, 2019Date of Patent: December 29, 2020Assignee: Purdue Research FoundationInventors: Jean Anne Chmielewski, Mohamed Seleem
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Patent number: 10876094Abstract: Provided are novel serum-free culture media which comprise basic fibroblast growth factor (bFGF), transforming growth factor beta-3 and ascorbic acid at a concentration of at least about 50 microgram/ml; ascorbic acid at a concentration range of about 400-600 microgram/ml, bFGF at a concentration range of about 50-200 ng/ml, xeno-free serum replacement and a lipid mixture; the IL6RIL6 chimera at a concentration range of about 50-200 picogram per milliliter (pg/ml); or leukemia inhibitory factor (LIF) at a concentration of at least 2000 units/ml; cell cultures comprising same with pluripotent stem cells such as human embryonic stem cells and induced pluripotent stem (iPS) cells, and methods of using same for expanding pluripotent stem cells in an undifferentiated state using two-dimensional or three-dimensional culture systems; and methods of expanding iPS cells in a suspension culture devoid of substrate adherence and cell encapsulation.Type: GrantFiled: April 27, 2015Date of Patent: December 29, 2020Assignee: Technion Research & Development Foundation LimitedInventors: Michal Amit, Joseph Itskovitz-Eldor
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Patent number: 10874854Abstract: The present invention relates to a mesh electrode for cardiac resynchronization therapy, and a manufacturing method therefor. More specifically, the present invention relates to: a mesh electrode for cardiac resynchronization therapy, formed from a wire composed of a first biocompatible rubber layer in which silver nanowires are dispersed, and a second biocompatible rubber layer famed so as to be adjacent to the first biocompatible rubber layer; and a manufacturing method therefor.Type: GrantFiled: March 31, 2015Date of Patent: December 29, 2020Assignees: Seoul National University R&DB Foundation, INSTITUTE FOR BASIC SCIENCEInventors: Dae-Hyeong Kim, Taeghwan Hyeon, Hye Jin Hwang, Jinkyung Park, Suji Choi
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Patent number: 10879452Abstract: A magnetic tunnel junction device and magnetic memory device. The magnetic tunnel junction device includes a magnetic tunnel junction including a fixed magnetic body, an insulator, and a free magnetic body sequentially stacked and a conducting wire disposed adjacent the free magnetic body of the magnetic tunnel junction to apply in-plane current. The fixed magnetic body has a fixed magnetization direction and is a thin film including a material magnetized directionally perpendicular to a film surface. The main free magnetic layer and the auxiliary free magnetic layer change in magnetization direction and is a thin film including a material magnetized directionally perpendicular to a film surface, and the main free magnetic layer is disposed adjacent to a conducting wire generating spin current by the in-plane current. Among magnetic layers constituting the free magnetic body, two magnetic layers closest to each other have opposite magnetization directions by an RKKY exchange interaction.Type: GrantFiled: April 27, 2020Date of Patent: December 29, 2020Assignee: Korea University Research and Business FoundationInventor: Kyung-Jin Lee
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Patent number: 10874900Abstract: Devices and methods for training the tongue and other muscles of the throat and upper respiratory airway to alleviate symptoms of snoring and the Obstructive Sleep Apnea Syndrome (OSAS) are provided. A threshold-load trainer, or similar device, having a biased tongue resistance pad is used for strengthening the muscles of the tongue to inhibit narrowing or obstruction of the upper respiratory airway, particularly during a state of relaxation or sleep. The threshold-load trainer embodiments of the subject invention can specifically target the genioglossus muscle under the tongue (the major tongue protruder) and other muscles of the throat and upper respiratory pathway, so as to improve muscle tonus.Type: GrantFiled: June 30, 2017Date of Patent: December 29, 2020Assignee: University of Florida Research Foundation, IncorporatedInventors: Richard Barnett Berry, Paul Wesley Davenport
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Patent number: 10877698Abstract: A semiconductor device may include a media controller configured to output a write requested address when a write request to a nonvolatile memory device is provided from a host; and a cold address manager. The cold address manager may include a stack storing meta data for the write requested address, region information storage configured to manage addresses of the nonvolatile memory device with regions such that length of a region of the regions may vary after a predetermined period, a cold address detector configured to update the stack and the region information storage after the predetermined period and to detect whether an address of the nonvolatile memory device is a cold address, the cold address having write requests performed at less than a predetermined level.Type: GrantFiled: June 6, 2019Date of Patent: December 29, 2020Assignees: SK hynix Inc., Seoul National University R&DB FoundationInventors: Hyunmin Jung, Sunwoong Kim, Hyokeun Lee, Woojae Shin, Hyuk-Jae Lee
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Patent number: 10874999Abstract: The mixing device of cell printing composition according to the present disclosure comprises a first syringe comprising a first container for containing first liquid, a first moving element discharging the first liquid contained in the first container; a second syringe comprising a second container for containing second liquid, a second moving element discharging the second liquid contained in the second container; a mixing container which comprises a rotating mixing unit and receives the discharged first liquid and the discharged second liquids; a power transmission unit for driving the first moving element, the second moving element and the mixing unit; a first threaded guide where the first moving element is movably connected; a second threaded guide where the second moving element is movably connected; and a rod for rotating the mixing unit.Type: GrantFiled: June 24, 2019Date of Patent: December 29, 2020Assignees: T&R BIOFAB CO., LTD., Korea Polytechnic University Industry Academic Cooperation FoundationInventors: Geunseon Ahn, Jinhyung Shim, Jeongseok Lee, Ingyu Lee, Kyunghyun Min, Songwan Jin, Wonsoo Yun
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Patent number: 10877209Abstract: A photonic device may include a lower cladding layer and a device layer. The device layer may include a first waveguide supporting TE and TM light, and a second waveguide, where a portion of a second waveguide core is proximate to a first waveguide core to provide evanescent coupling. The first waveguide core is formed from one of a first core structure or a second core structure, and the second waveguide core is formed from the other structure. The first core structure has an index of refraction nM. The second core structure is formed as alternating layers providing an effective index of refraction for TE polarized light nTE and an effective index of refraction for TM polarized light nTM, where nTM<nM<nTE such that one of TM or TE light is preferentially evanescently coupled between the first waveguide and the second waveguide.Type: GrantFiled: January 7, 2020Date of Patent: December 29, 2020Assignee: Univeristy of Central Florida Research Foundation, Inc.Inventors: Jeffrey Chiles, Sasan Fathpour
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Patent number: 10880148Abstract: The disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as long term evolution (LTE). According to various embodiments, a transmission device in a wireless environment may include a transceiver, and a processor operatively coupled to the transceiver. The processor may be configured to generate a codeword related to transmission data, generate symbols from the codeword by using a plurality of transmission symbol vectors determined using a linear combination of vectors corresponding to respective rows of a lattice generation matrix, and transmit a signal generated based on the symbols via the transceiver.Type: GrantFiled: August 17, 2018Date of Patent: December 29, 2020Assignees: Samsung Electronics Co., Ltd., Postech Academy-Industry FoundationInventors: Jongbu Lim, Namyoon Lee, Jiwook Choi, Chanhong Kim, Yeohun Yun, Sungnam Hong
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Patent number: 10876957Abstract: An imaging system for a smartphone includes a housing configured to rigidly attach to a handheld smartphone device. The system further includes an arm extending from the housing, wherein the arm is configured to be adjustable such that the arm is movable toward and away from the housing. Additionally, the system includes a sample mounting portion attached to the arm, the mounting portion having a retaining device, wherein the retaining device is configured to secure a target sample, the mounting portion configured to direct an image of the target sample to a first camera in the handheld smartphone device.Type: GrantFiled: December 6, 2019Date of Patent: December 29, 2020Assignee: Purdue Research FoundationInventor: Jian Jin
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Patent number: 10876904Abstract: A system, a method of use, and a Carbon Nanotube (CNT) condensation sensor for determining a dew point and/or ice point is provided. For example, a sensing system may include a thermal device configured to generate heating or cooling to change a temperature of a surface, a temperature sensor for measuring the temperature of the surface, a controller configured to control the thermal device, a carbon nanotube (CNT) condensation sensor mounted on the surface having a moisture sensitive resistance and a processor configured to determine one or more parameters based on the moisture sensitive resistance of the CNT condensation sensor and the temperature measured by the temperature sensor. The one or more parameter can be used to determine the dew point and/or ice point. A method for forming a carbon nanotube (CNT) condensation sensor is also provided.Type: GrantFiled: September 19, 2018Date of Patent: December 29, 2020Assignees: The Research Foundation for The State University of New York, Cosa XentaurInventors: Vladimir Samuilov, John Lewis Ayres
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Patent number: 10875923Abstract: This document provides methods and materials for detecting B7-H1 polypeptides (e.g., soluble B7-H1 polypeptides). For example, antibodies (e.g., monoclonal antibodies) that bind to a B7-H1 polypeptide (e.g., a soluble B7-H1 polypeptide) are provided.Type: GrantFiled: October 26, 2016Date of Patent: December 29, 2020Assignee: Mayo Foundation for Medical Education and ResearchInventor: Haidong Dong
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Patent number: 10874715Abstract: The application provides new compositions and methods for stimulating the production of natural killer (NK) cells in a subject. NK cells can be selectively expanded with a combination of stimulating ligands. Methods and compositions for the administration of stimulatory ligands modified to self-insert into tumor cells, thereby stimulating an increase in the number of NK cells in proximity to a tumor, are also described.Type: GrantFiled: September 21, 2018Date of Patent: December 29, 2020Assignee: University of Central Florida Research Foundation, Inc.Inventors: Alicja Copik, Vijay Reddy, Jeremiah Oyer
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Patent number: 10875191Abstract: A present disclosure relates to a shape compliant electroadhesive gripper for picking up atypical objects having various shapes, sizes, and materials, and a shape compliant electroadhesive gripper according to one embodiment of the present disclosure includes a body, a shape compliant module disposed on the body, rigidity of the shape compliant modules being variably controllable, and an electroadhesive module disposed on the shape compliant module.Type: GrantFiled: June 29, 2018Date of Patent: December 29, 2020Assignees: DAWOOFA CO., LTD, Korea University Of Technology And Education Industry-University Cooperation Foundation, DAEGU Gyeongbuk Institute Of Science And TechnologyInventors: Hae Sook Hwang, Hyung Chul Kim, Dong Won Yun, Sang Youn Kim, Kyoung Bok Jin
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Patent number: 10878086Abstract: A dynamic code extraction-based automatic anti-analysis evasion and code logic analysis apparatus, includes: a recognition module that extracts a DEX file and a SO file by unpacking an execution code of an application and recognizes an analysis avoidance technique by comparing a signature which is included in the extracted DEX file and SO file; a instrumentation module that extracts a code to be analyzed from a byte code configuring the DEX file and a native code configuring the SO file, compares the extracted code with the data stored in a database, and outputs a code excluding an anti-analysis technique as a log file; and a deobfuscation module that deobfuscates an obfuscated code which is included in the APK on the basis of the output log file and generates an APK file in which an obfuscation technique is released on the basis of the deobfuscated code.Type: GrantFiled: November 22, 2018Date of Patent: December 29, 2020Assignee: Foundation of Soongsil University-Industry CooperationInventors: Jeong Hyun Yi, Jongsu Lim, Sun Jun Lee, Yong Gu Shin, Kyu Ho Kim
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Patent number: 10875960Abstract: A silane-modified polyester blend comprising a polyester polymer homogeneously blended with silane molecules containing two or three alkoxy groups bound to the silicon atom, wherein said silane molecules are present in said polyester blend in an amount of 0.05-20 wt % (or, e.g., 0.05-10 wt %, 0.05-5 wt %, or 0.05-2 wt %). The polyester polymer may, in particular embodiments, be a polyhydroxyalkanoate, terephthalate-based polyester, adipate-based, or succinate-based polyester. The silane molecule may be according to the formula (R2O)2SiR3R4, wherein R2 groups are independently selected from alkyl groups containing 1-4 carbon atoms; and R3 and R4 are independently selected from OR2 groups and alkyl groups containing 1-12 carbon atoms, provided that at least one of R3 and R4 is an alkyl group, wherein the alkyl group optionally includes one or more heteroatoms selected from oxygen, nitrogen, halogen, sulfur, phosphorus, and silicon. Methods for producing the silane-modified polyester blend are also described.Type: GrantFiled: August 23, 2018Date of Patent: December 29, 2020Assignees: UT-Battelle, LLC, University of Tennessee Research FoundationInventors: Xiangtao Meng, Soydan Ozcan, Halil Tekinalp
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Patent number: 10874684Abstract: Compositions and method are therefore disclosed for treating ARDS. In particular, disclosed a composition that contains one, two, or more cytidine diphosphate (CDP)-conjugated precursors selected from the group consisting of CDP-choline, CDP-ethanolamine, and CDP-diacylglycerol (CDP-DAG) in a pharmaceutically acceptable carrier for use in treating ARDS.Type: GrantFiled: December 21, 2018Date of Patent: December 29, 2020Assignee: Ohio State Innovation FoundationInventor: Ian Christopher Davis
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Patent number: 10875970Abstract: The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network.Type: GrantFiled: November 21, 2019Date of Patent: December 29, 2020Assignee: Colorado State University Research FoundationInventors: William Scott Compel, Christopher J. Ackerson, O. Andrea Wong
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Patent number: 10879817Abstract: A paper-based triboelectric nanogenerator and a method of manufacturing the same are disclosed. The paper-based triboelectric nanogenerator of the present disclosure includes a sandwich structure including a first paper, conductive papers formed on the first paper and each including an electrode composed of a mesh-type conductive nanomaterial, and a second paper formed on the conductive papers; and a polymer film formed in a selective area on the second paper, wherein the number of the conductive papers formed on the first paper is two; the two conductive papers are formed so as to be spaced apart from each other in the horizontal direction; and the polymer film formed in the selective area is formed only in the upper area of one of the two conductive papers.Type: GrantFiled: November 30, 2018Date of Patent: December 29, 2020Assignee: Industry-University Cooperation Foundation Hanyang UniversityInventors: Tae Whan Kim, Chaoxing Wu, Jae Hyeon Park