Patents Assigned to FRED
  • Patent number: 5420564
    Abstract: Door chime assembly includes a chime base having a rear plate and at least one resonance chamber secured to said rear plate, a tone bar within the chamber and a striking means mounted on the plate for striking the tone bar. The chime base is molded in a single piece and employs at least one living hinge which permits folding of parts of the assembly to form the resonance chamber. The tone bar is mounted on dowels in the chamber of a length which prevents the tone bar from falling off the dowels during transit.
    Type: Grant
    Filed: July 14, 1993
    Date of Patent: May 30, 1995
    Assignee: Fred M. Schildwachter & Sons, Inc.
    Inventor: Duncan Remington
  • Patent number: 5411012
    Abstract: A propane heater suitable for orchards, having a cylindrical combustion chamber and an exhaust tube which extends from one end thereof, the exhaust tube being substantially longer than the combustion chamber. A fuel inlet is located in the cylindrical surface of the combustion chamber at the other end thereof, at approximately 30.degree. from top dead center thereof. An ignition and air supply tube is located approximately 80.degree.-110.degree. circumferentially away from the fuel inlet, past the top dead center of the chamber.
    Type: Grant
    Filed: October 5, 1993
    Date of Patent: May 2, 1995
    Assignees: Fred A. Tull, Rosa B. Tull
    Inventor: Larry D. Kellog
  • Patent number: 5392202
    Abstract: An illuminated electrical push button switch has a pair of spring contacts secured in a plug-like body on either side of a miniature bulb. A flat top, metallic cup-shape, push button overlies the contacts, insulated therefrom by a sheet of electrical insulating material. The push button has a plurality of circumferentially spaced radially projecting fingers. A cylindrical shell with a radially inwardly directed flange fits over the plug-like body with a snug fit with the flange overlying the fingers of the push button to secure the push button to the body. A plurality of circumferentially spaced notches in the flange of the shell provide openings through which light emanating from the lamp can escape. The entire assembly has a low profile and is mounted by means of an adhesive. The assembly can be mounted directly on the building structure or it can be mounted with a decorative plate or the like interposed between the building and push button assembly.
    Type: Grant
    Filed: May 13, 1994
    Date of Patent: February 21, 1995
    Assignee: Fred M. Schildwachter & Sons, Inc.
    Inventor: William L. Herron
  • Patent number: 5352595
    Abstract: Isolated DNA or RNA molecules capable of hybridizing under stringent conditions to the myoD regulatory region, its proximal promoter and distal enhancer regulatory regions, and regulatory elements within the proximal and distal regions for binding basic helix-loop-helix proteins, MyoD, and proteins binding at SP1, AP1, CAAT, M-CAT, CArG, and MEF sites in DNA. DNA or RNA expression vectors for introducing a gene into a cell under the regulatory control of the myoD regulatory region. Transduced or transfected pre-muscle cells, myocytes, or myoblasts. Methods of inducing a muscle phenotype in a non-muscle cell, positively selecting for a cells expressing MyoD, and negatively selecting for cells expressing MyoD.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: October 4, 1994
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Stephen J. Tapscott, Harold M. Weintraub, Theodore D. Palmer
  • Patent number: 5352072
    Abstract: A cutting tool for trimming a laminate flush with the surface of a substantially perpendicular laminate. The cutting tool includes a ball bearing guide assembly and a glue well shaft section. This glue well shaft section prevents softened glue encountered during trimming operations from contacting the ball bearing guide assembly. A washer provided between the glue well shaft section and the ball bearing guide assembly further prevents softened glue encountered during trimming operations from contacting the ball bearing guide assembly.
    Type: Grant
    Filed: March 1, 1993
    Date of Patent: October 4, 1994
    Assignee: Fred M. Velepec Co., Inc.
    Inventor: Fredric A. Velepec
  • Patent number: 5336190
    Abstract: A method for resupplying a cassette assembly (14) for an ambulatory medical infusion pump (10) with a new reservoir bag (22a) includes the steps of substantially emptying a used reservoir bag (22) located within said cassette interior (27) of any fluid, supplying an access slot (40) to the interior (27) of the cassette large enough to withdraw the used drug reservoir bag (22) from within the cassette, removing a luer lock (34) located at the end of microbore tubing (32) attached to the reservoir bag, removing the tubing (32) from under a guide retainer (30) in a pumping plate (16) of the cassette, withdrawing the reservoir bag (22) from the access slot (40), inserting a new unused reservoir bag (22a) into the access slot (40) to the interior of said cassette, by inserting a tube (32a) of a new unused reservoir bag and pulling the tube (32a) such that the bag (22a) is pulled through the slot (40) and into the interior (27) of the cassette shell (18).
    Type: Grant
    Filed: August 12, 1993
    Date of Patent: August 9, 1994
    Assignees: Fred Erlich, Fred Kamienny, Richard Moss
    Inventors: Richard Moss, Fred Erlich
  • Patent number: 5302519
    Abstract: Nucleic acid molecules capable of hybridizing under stringent conditions to the nucleotide sequence residing between positions 1 and 453 of the max cDNAs shown in FIG. 2, or to the nucleotide sequence residing between positions 148 and 810 of the mad cDNAs shown in FIG. 14. The Max polypeptide when associated with the Myc or Mad polypeptide is capable of binding to nucleotide sequences containing CACGTG.
    Type: Grant
    Filed: June 23, 1992
    Date of Patent: April 12, 1994
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Elizabeth M. Blackwood, Robert N. Eisenman, Donald E. Ayer, Jr.
  • Patent number: 5300630
    Abstract: An onco-developmentally regulated .alpha.-N-acetylgalactosaminyltransferase isolated as a component of a particulate membrane fraction separated from cell and tissue homogenates and having the following characteristics:(a) Activity in Various Cells and Tissues--present in human fetal lung fibroblasts, hepatoma tissues and placenta, but absent from normal adult liver, lung, kidney and spleen tissues;(b) Substrate Specificity--acts on polypeptides comprising a sequence val-thr-his-pro-gly-tyr by catalyzing u-N-acetylgalactosaminylation at the thr residue of the sequence;(c) Requirements for Metal Ion--requires metal ion for activity in 25 mM tris buffer, pH 7.6;(d) Optimal pH--optimal pH is about 7.6 assayed in hepatoma cell homogenate in tris buffer and at a pH of about 6 to about 7 assayed in hepatoma cell homogenate enzyme activity is higher in 2(N-morpholino)ethanesulfonic acid than in cacodylate buffer; and(e) Km--apparent Km for UDP - GalNAc is about 48 .mu.M.
    Type: Grant
    Filed: October 2, 1992
    Date of Patent: April 5, 1994
    Assignees: Fred Hutchinson Cancer Research Institute, The Biomembrane Institute, The Board of Regents of the University of Washington
    Inventors: Hidemitsu Matsuura, Sen-itiroh Hakomori, Koiti Titani
  • Patent number: 5277173
    Abstract: A chemiluminiscent, disposable laryngoscope is disclosed. The device comprises a handle portion with an end and a blade portion which is integrally formed on the end of the handle portion. The blade points away from the handle portion substantially perpendicularly. Inside the blade there is disposed a container which, upon activation, provides chemiluminiscent light. The blade is, at least in portions thereof, formed of translucent material. The unit is selfcontained, self-lighting and disposable as a whole.
    Type: Grant
    Filed: October 9, 1992
    Date of Patent: January 11, 1994
    Assignee: Fred Cantele
    Inventor: Fred Cantele
  • Patent number: 5277734
    Abstract: A method and an apparatus for making a conductive circuit in sheet form. A circuit trace is firstly designed using a CAD (computer aided design) system and a computer aided cutting device is operated by the CAD to cut the desired circuit trace in a thin foil sheet which is adhesively secured to a release backing sheet. The non-circuit trace portions of the foil sheet are removed from the adhesive release backing sheet leaving only the circuit trace. An adhesive transfer sheet is then used to remove the actual circuit trace, in an undisturbed manner, from the release sheet and applied it to a support base. Because the circuit trace has an adhesive backing, it will adhere to the support base. A multi-layer flexible electric conductive circuit can also be fabricated with this method and the transfer sheet can also be utilized as an insulating layer.
    Type: Grant
    Filed: November 7, 1991
    Date of Patent: January 11, 1994
    Assignee: Fred Bayer Holdings Inc.
    Inventor: Alfred H. B. Bayer
  • Patent number: 5273738
    Abstract: A method of selectively delivering radiation homogeneously to lymphoid and marrow tissues in vivo including the step of administering an effective dose of a radiolabeled immunological binding partner of a T-200 antigen to a patient is disclosed. Also disclosed are immunological binding partners and compositions based thereon for carrying out the method.
    Type: Grant
    Filed: March 3, 1990
    Date of Patent: December 28, 1993
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Dana C. Matthews, Irwin D. Bernstein, John A. Hansen, Fred R. Appelbaum, Claudio Anasetti, Paul J. Martin
  • Patent number: 5264356
    Abstract: Glucosidase I inhibitors as therapeutic agents for combatting nondefective retroviral pathogens, including the aetiological agents of AIDS and feline leukemia. Administration of a processing glucosidase I inhibitor, preferably castanospermine, interrupts the replication of the retrovirus in infected cells, alleviates pathogenic effects associated with the presentation of viral env glycoproteins on infected cells, and may furthermore prevent infection of target cells by interrupting expression of endogenous receptors recognized by the virion.
    Type: Grant
    Filed: October 30, 1991
    Date of Patent: November 23, 1993
    Assignee: Fred Hutchinson Cancer Research Center
    Inventor: Larry R. Rohrschneider
  • Patent number: 5261447
    Abstract: The invention is an improvement in a pneumatic regulating valve of the type having a main flow path and a bleed passage. In the improvement, the bleed passage is in parallel with the main flow path and regulates a downward-trending pressure at the outlet port to prevent such pressure from diminishing or from rapidly diminishing. The valve also includes a check valve in series with the bleed passage for regulating an upward-trending pressure at the outlet port. Using a constant bleed orifice to substantially pressure-balance the check valve and a small-area protrusion on the check valve to reduce contact area, the check valve exhibits very low hysteresis.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: November 16, 1993
    Assignee: Fred Knapp Engraving Co., Inc.
    Inventor: John A. Boticki
  • Patent number: 5262334
    Abstract: The selectivity of immunoselection systems employing insolubilized avidin and biotinylated specific antibody is amplified, and nonspecific recovery is improved, by employing an indirect sandwich technique using a biotin-conjugated antispecies immunoglobulin that is directed to one or more nonbiotinylated specific antibodies in conjunction with insolubilized avidin. Specific cell populations can be removed and recovered from bone marrow, providing excellent recovery of bone marrow and preservation of hematopoietic stem cells for transplantation. Mixed populations of T cells or of tumor cells can be conveniently and simultaneously removed with minimal manipulation of the marrow cells. An improved positive immunoselection method provides viable and functional recovered cells, e.g., hematopoietic stem cells or activated killer cells, that can be clinically employed.
    Type: Grant
    Filed: October 3, 1991
    Date of Patent: November 16, 1993
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Ronald J. Berenson, William I. Bensinger
  • Patent number: 5262409
    Abstract: Method for killing a cycling cell, by contacting the cell with a first agent that blocks progression of the cell cycle in the cell, and thereafter contacting the cell with a second agent that overrides the cell cycle block such that the cell proceeds past mitosis and cell death results within an additional cell cycle due to aberrant DNA replication or chromosome segregation. The first agent blocks the progression of the G.sub.1, S, G.sub.2, or mitosis stage of the cell cycle. The second agent is preferably 2-aminopurine (2-AP) or 6-dimethylaminopurine (6-DMAP). The duration of contact with the first agent is advantageously limited to a first time period sufficient to block the progression of the cell cycle, and the duration of contact with the second agent is limited to a second time period sufficient to override the cell cycle block.
    Type: Grant
    Filed: October 11, 1991
    Date of Patent: November 16, 1993
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Robert L. Margolis, Paul R. Andreasson
  • Patent number: 5253441
    Abstract: A listing device is disclosed for recording domestic household items which must be purchased on an ongoing basis and for indicating chores and appointments which must be regularly observed. The listing device includes a planar support sheet and plate displaying an itemized shopping list attached to the sheet. The itemized shopping list comprises items arranged sequentially in two vertical columns. The sheet is attached to one side of a backing. Another support sheet and plate with itemized shopping list may be attached to the other side of the backing and several backings can be retained in a hand-held binder or booklet. A visual indicator, such as a bright color patch is located adjacent to each visually discernable item on the list. A cover tab for covering the color patches are included and are movable between a covering position in which the color patch is covered and an uncovering position in which the visual indicator is uncovered thereby drawing the user's attention to that particular item on the list.
    Type: Grant
    Filed: May 4, 1992
    Date of Patent: October 19, 1993
    Assignee: Fred Rachiele
    Inventors: Fred Rachiele, Ray Anderson
  • Patent number: 5243029
    Abstract: Antibody defining structure present in fibronectins from tumors and fetal tissues but absent in fibronectins from normal adult tissues and plasma; useful for diagnosing and treating human cancers.
    Type: Grant
    Filed: November 4, 1991
    Date of Patent: September 7, 1993
    Assignee: Fred Hutchinson Cancer Research Center
    Inventors: Hidemitsu Matsuura, Sen-Itiroh Hakomori
  • Patent number: 5238451
    Abstract: A light eliminator which permits passage of ventilating air but totally eliminates entry of light into the poultry house which includes a plurality of laterally spaced vertical fins or panels each of which is of a unique configuration which breaks the light four times in order to totally block the entry of light into a poultry house while maintaining a minimum air flow resistance with the fins being spaced apart by standoffs that are uniquely positioned with the fins generally being of W-shaped configuration whereby negative pressure within the poultry house provided by air circulating fans will not cause vibration or waffling of the fins when subjected to air velocities induced by high CFM capacity poultry house fans. The light eliminator is constructed of noncorrosive plastic material and can be assembled easily in a short period of time and is extremely durable resulting in low cost operation.
    Type: Grant
    Filed: February 19, 1992
    Date of Patent: August 24, 1993
    Assignee: Fred A. Wulf
    Inventors: Fred A. Wulf, Robert Barnwell
  • Patent number: 5226205
    Abstract: The invention concerns an hydraulic machine, typically a submerged surface cleaner which comprises a body having a liquid inlet and a liquid outlet and a conduit extending between the inlet and the outlet. A drive element is supported in or adjacent to the conduit, with a clearance between the drive element and the interior of the conduit, in a manner permitting eccentric location and rotation of the drive element relative to the conduit. The conduit can be connected in a liquid flow path so that liquid passing through the conduit past the drive element, when the drive element is positioned eccentrically relative to the conduit, applies differential forces to the drive element to cause it to rotate relative the conduit. The rotation of the drive element is used directly or indirectly to drive the cleaner over a submerged surface.
    Type: Grant
    Filed: September 11, 1991
    Date of Patent: July 13, 1993
    Assignee: Fred International C.V.
    Inventor: Ronald J. Pearce
  • Patent number: PP8362
    Abstract: A new variety of floribunda rose having multi-colored apricot and red flowers.
    Type: Grant
    Filed: February 5, 1992
    Date of Patent: September 7, 1993
    Assignee: Roses by Fred Edmunds, Inc.
    Inventor: Sam McGredy, IV