Abstract: A high-strength steel allowing low-temperature welding and high-heat input welding and a production method thereof are provided, which belongs to the technical field of steel production. The high-strength steel includes the following chemical components by mass fraction: 0.03-0.16% of C, 0.05-0.5% of Si, 1.0-1.9% of Mn, 0.002-0.02% of P, 0.001-0.01% of S, 0.005-0.07% of A1, 0.005-0.04% of Ti, 0.1-0.5% of Cr, 0.0005-0.005% of B, 0.002-0.01% of Mg+Zr, 0.001-0.008% of O, 0.004-0.01% of N, and the balance of Fe and residual elements. Magnesium and zirconium are added to form magnesium/zirconium oxide, titanium and boron are added to form titanium/boron nitride, and the two types of precipitates work synergistically to improve the microstructure of a heat-affected zone. The method optimizes the chemical composition and production process of existing high-strength steel.

Abstract: A method and corresponding system identify missing interactions in incompletely known datasets represented as complex networks. The method identifies missing connections in a complex network. The method accesses an electronic representation of the network. The network includes nodes and links, the nodes represent entities, and the links represent interactions between the entities. For each pair of nodes not directly connected by a link, the method determines a number of paths connecting the pair of nodes and calculates a prediction score for the pair of nodes based on the number of paths connecting the pair of nodes. The method ranks the pairs of nodes based on the prediction scores, resulting in an ordered list of node pairs, and selects at least a subset of the pairs of nodes based on the ordered list of node pairs. The selected pairs of nodes represent missing connections in the network.

Abstract: Pharmaceutical formulations (nanococktails) include two or more nanoparticulate delivery vehicles each including an active agent. The nanococktails can be formulated at any ratio of active agents by changing the ratio of nanoparticulate delivery vehicles in the nanococktail. The nanoparticulate delivery vehicles can have matched surface potential to prevent aggregation. The nanoparticulate delivery vehicles of the combined formulation are designed to provide each active agent with desired, preferably overlapping therapeutic windows and a specifically selected pharmacokinetic and pharmacodynamic profile when the nanococktail is administered to a subject. Each of the nanoparticulate delivery vehicles can be designed to enhance solubility, duration of action, targeting, stability, and to program release while preventing degradation of an active agent and preventing side effects, toxicity, and tolerability issues in a subject.

Abstract: An apparatus and corresponding method for frontal face synthesis. The apparatus comprises a decoder that synthesizes a high-resolution (HR) frontal-view (FV) image of a face from received features of a low-resolution (LR) non-frontal-view (NFV) image of the face. The HR FV image is of a higher resolution relative to a lower resolution of the LR NFV image. The decoder includes a main path and an auxiliary path. The auxiliary path produces auxiliary-path features from the received features and feeds the auxiliary-path features produced into the main path for synthesizing the HR FV image. The auxiliary-path features represent a HR NFV image of the face at the higher resolution. As such, an HR identity-preserved frontal face can be synthesized from one or many LR faces with various poses and may be used in types of commercial applications, such as video surveillance.

Abstract: A preparation method of a granular adsorbent is provided, including the following: adding a pyrrole monomer to an acidic solution, and adding an oxidant as an initiator to allow a polymerization reaction of the pyrrole monomer to produce polypyrrole (PPy), where an adsorption material powder is added to a reaction system before, during, or immediately after the polymerization reaction, and a resulting mixture is thoroughly stirred; after the polymerization reaction is completed, filtering a resulting reaction system to obtain a filter cake, which is the granular adsorbent; or subjecting the resulting reaction system to centrifugal sedimentation to obtain the monolithic adsorbent. In the present disclosure, the pyrrole monomer is subjected to a polymerization reaction to generate PPy; before being tightly stacked, network structures of PPy wrap the adsorption material powder; and the granular adsorbent is formed through sedimentation and stacking.

Abstract: A machine learning (ML) agent operates at a transmitter to optimize signals transmitted across a communications channel. A physical signal modifier modifies a physical layer signal prior to transmission as a function of a set of signal modification parameters to produce a modified physical layer signal. The ML agent parses a feedback signal from a receiver across the communications channel, and determines a present tuning status as a function of the signal modification parameters and the feedback signal. The ML agent generates subsequent signal modification parameters based on the present tuning status and a set of stored tuning statuses, thereby updating the physical signal modifier to generate a subsequent modified physical layer signal to be transmitted across the communications channel.

Abstract: Apparatuses and methods for real-time spectrum-driven embedded wireless networking through deep learning are provided. Radio frequency, optical, or acoustic communication apparatus include a programmable logic system having a front-end configuration core, a learning core, and a learning actuation core. The learning core includes a deep learning neural network that receives and processes input in-phase/quadrature (I/Q) input samples through the neural network layers to extract RF, optical, or acoustic spectrum information. A processing system having a learning controller module controls operations of the learning core and the learning actuation core. The processing system and the programmable logic system are operable to configure one or more communication and networking parameters for transmission via the transceiver in response to extracted spectrum information.

Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer.

Abstract: An analog computing method includes the steps of: (a) generating a biasing current (IWi) using a constant gm bias circuit operating in the subthreshold region for ultra-low power consumption, wherein gm is generated by PMOS or NMOS transistors, the circuit including a switched capacitor resistor; and (b) multiplying the biasing current by an input voltage using a differential amplifier multiplication circuit to generate an analog voltage output (VOi). In one or more embodiments, the method is used in a vision application, where the biasing current represents a weight in a convolution filter and the input voltage represents a pixel voltage of an acquired image.

Abstract: A flexible head probe and modular head probe system that includes an optical functional near-infrared spectroscopy (fNIRS) system and integrated position sensor. The head probe and modular head probe system determines physiological data based upon the optical information gathered by the fNIRS system and gathers motion and position data from the position sensor. The physiological data and motion and position data are combined to permit topographical and tomographic analyses of a user's brain tissue.

Abstract: Methods and systems providing adaptive assessment of a physical subject to efficiently collect assessment data and modify an assessment schedule based on the analyses. The methods and systems can control the timing of each assessment in order to collect data at times and under conditions that are most informative about the physical subject. Such adaptive methods and systems significantly minimize the frequency of data collection without loss in accuracy or precision and can increase test reliability through reduction in redundancy. The ability to estimate an unknown, underlying function using a small number of free parameters that remain constant regardless of the number of data points being estimated substantially reduces the error of the function estimate. Because estimates of the measurement error are achieved with a minimum of sampled assessments, and with great accuracy, the statistical power of clinical trials, for example, can be greatly increased.

Abstract: The present disclosure is directed towards a method of treating a disease or condition associated with gut inflammation. The present disclosure comprises administering, to a patient in need thereof, a composition comprising oxygen-scavenging membrane fragments or membrane vesicles. In some embodiments, membrane vesicles are derived from bacteria. In some embodiments, membrane vesicles are derived from the cytoplasmic membranes of Escherichia coli, Salmonella typhimurium, Gluconobacter oxydans, Pseudomonas aeruginosa, or Acetobacter.

Abstract: A system and method for beam management in a wireless network are provided. A learning module having a trained classification module processes received I/Q input samples to determine transmitted beam information of incoming RF transmissions. The learning module includes a beam inference engine to determine waveform characteristics of incoming RF transmissions, and an angle of arrival engine operative to determine an angle of arrival of the incoming RF transmissions on an antenna array. An incoming RF transmission and angle of arrival are selected based on the determined waveforms for beam management operations.

Abstract: Aspects of the present disclosure describe systems and methods for predicting an intra-aortic pressure of a patient receiving hemodynamic support from a transvalvular micro-axial heart pump. In some implementations, an intra-aortic pressure time series is derived from measurements of a pressure sensor of the transvalvular micro-axial heart pump and a motor speed time series is derived from a measured back electromotive force of a motor of the transvalvular micro-axial heart pump. Furthermore, in some implementations, machine learning algorithms, such as deep learning, are applied to the intra-aortic pressure and motor speed time series to accurately predict an intra-aortic pressure of the patient. In some implementations, the prediction is short-term (e.g., approximately 5 minutes in advance).

Abstract: Disclosed herein are compositions and methods for the treatment and/or detection of diseases such as, but not limited to Lyme disease, Lyme disease-related disorders including post-treatment Lyme disease syndrome (PTLDS), chronic Lyme disease (CLD) and/or inflammation.

Abstract: An underwater acoustic communication system for a mobile electronic device, such as a smartphone, has a communication unit with one or more ultrasonic transducers to transmit and receive underwater ultrasonic signals. The communication unit is connected to an audio auxiliary interface of the mobile electronic device. A processing unit in communication with the auxiliary interface receives RF signals from and transmits RF signals to the communication unit via the audio auxiliary interface.

Abstract: A method for transforming a crystal form of an electrolyte containing lithium for aluminum electrolysis includes the following steps: S1, pulverizing the electrolyte containing lithium; S2, uniformly mixing an additive with the electrolyte powder to obtain a mixture, wherein the additive is one or more selected from the group consisting of an oxide of an alkali metal other than lithium, an oxo acid salt of an alkali metal other than lithium, and a halide of an alkali metal other than lithium; a molar ratio of a sum of alkali metal fluoride contained in the electrolyte, alkali metal fluoride directly added from the additive, and alkali metal fluoride to which the additive is converted under the high-temperature calcination condition in the mixture to aluminum fluoride is greater than 3; S3, calcining the mixture at a high temperature.

Abstract: Biologically-inspired compositions, including color changing compositions, and corresponding embodiments such as sensors, textile materials, coatings and films, are provided which typically include a solid, transparent and nondegradable matrix. The matrix contains a plurality of (i) synthetic particles having a size in the micrometer or nanometer range, each synthetic particle including one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45, the aggregates having a size larger than about 100 nm; or (ii) submicrometer natural particles extracted and purified from homogenized tissue.

Abstract: Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.

Abstract: Methods disclosed herein provide for an environmentally-friendly approach that employ citric extracts from fruits as unique reducing and stabilizing agents for making a tellurium nanomaterial. A particular method of making a tellurium nanomaterial includes combining citrus fruit extract with a tellurium salt to form a mixture of citrus fruit extract and dissolved tellurium salt; and heating the mixture of citrus fruit extract and dissolved tellurium salt, thereby making the tellurium nanomaterial. The resulting nanoparticles exhibit enhanced and desirable biomedical properties toward treatment of both infectious diseases and cancer.