Abstract: A system and method for beam management in a wireless network are provided. A learning module having a trained classification module processes received I/Q input samples to determine transmitted beam information of incoming RF transmissions. The learning module includes a beam inference engine to determine waveform characteristics of incoming RF transmissions, and an angle of arrival engine operative to determine an angle of arrival of the incoming RF transmissions on an antenna array. An incoming RF transmission and angle of arrival are selected based on the determined waveforms for beam management operations.
Type:
Grant
Filed:
September 22, 2021
Date of Patent:
February 21, 2023
Assignee:
Northeastern University
Inventors:
Michele Polese, Francesco Restuccia, Tommaso Melodia
Abstract: Aspects of the present disclosure describe systems and methods for predicting an intra-aortic pressure of a patient receiving hemodynamic support from a transvalvular micro-axial heart pump. In some implementations, an intra-aortic pressure time series is derived from measurements of a pressure sensor of the transvalvular micro-axial heart pump and a motor speed time series is derived from a measured back electromotive force of a motor of the transvalvular micro-axial heart pump. Furthermore, in some implementations, machine learning algorithms, such as deep learning, are applied to the intra-aortic pressure and motor speed time series to accurately predict an intra-aortic pressure of the patient. In some implementations, the prediction is short-term (e.g., approximately 5 minutes in advance).
Type:
Grant
Filed:
June 1, 2020
Date of Patent:
February 14, 2023
Assignees:
Abiomed, Inc., Northeastern University
Inventors:
Ahmad El Katerji, Erik Kroeker, Elise Jortberg, Rose Yu, Rui Wang
Abstract: Disclosed herein are compositions and methods for the treatment and/or detection of diseases such as, but not limited to Lyme disease, Lyme disease-related disorders including post-treatment Lyme disease syndrome (PTLDS), chronic Lyme disease (CLD) and/or inflammation.
Type:
Application
Filed:
December 10, 2020
Publication date:
February 9, 2023
Applicant:
Northeastern University
Inventors:
Kim LEWIS, Madeleine MORRISSETTE, Philip STRANDWITZ, Anthony D'ONOFRIO, Norman PITT
Abstract: An underwater acoustic communication system for a mobile electronic device, such as a smartphone, has a communication unit with one or more ultrasonic transducers to transmit and receive underwater ultrasonic signals. The communication unit is connected to an audio auxiliary interface of the mobile electronic device. A processing unit in communication with the auxiliary interface receives RF signals from and transmits RF signals to the communication unit via the audio auxiliary interface.
Type:
Grant
Filed:
May 30, 2018
Date of Patent:
February 7, 2023
Assignee:
Northeastern University
Inventors:
Francesco Restuccia, Emrecan Demirors, Tommaso Melodia
Abstract: Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease.
Abstract: Biologically-inspired compositions, including color changing compositions, and corresponding embodiments such as sensors, textile materials, coatings and films, are provided which typically include a solid, transparent and nondegradable matrix. The matrix contains a plurality of (i) synthetic particles having a size in the micrometer or nanometer range, each synthetic particle including one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45, the aggregates having a size larger than about 100 nm; or (ii) submicrometer natural particles extracted and purified from homogenized tissue.
Type:
Grant
Filed:
September 25, 2018
Date of Patent:
January 31, 2023
Assignees:
Northeastern University, US Government as Represented by the Secretary of the Army
Inventors:
Leila Deravi, Camille A. Martin, Amrita Kumar, Richard M. Osgood, III
Abstract: Methods disclosed herein provide for an environmentally-friendly approach that employ citric extracts from fruits as unique reducing and stabilizing agents for making a tellurium nanomaterial. A particular method of making a tellurium nanomaterial includes combining citrus fruit extract with a tellurium salt to form a mixture of citrus fruit extract and dissolved tellurium salt; and heating the mixture of citrus fruit extract and dissolved tellurium salt, thereby making the tellurium nanomaterial. The resulting nanoparticles exhibit enhanced and desirable biomedical properties toward treatment of both infectious diseases and cancer.
Type:
Grant
Filed:
March 13, 2020
Date of Patent:
January 24, 2023
Assignee:
Northeastern University
Inventors:
David Medina Cruz, William Tien-Street, Bohan Zhang, Xinjing Huang, Ada Vernet Crua, Thomas J. Webster
Abstract: A zero-power plasmonic microelectromechanical system (MEMS) device is capable of specifically sensing electromagnetic radiation and performing signal processing operations. Such devices are highly sensitive relays that consume no more than 10 nW of power, utilizing the energy in detected electromagnetic radiation to detect and discriminate a target without the need of any additional power source. The devices can continuously monitor an environment and wake up an electronic circuit upon detection of a specific trigger signature of electromagnetic radiation, such as vehicular exhaust, gunfire, an explosion, a fire, a human or animal, and a variety of sources of radiation from the ultraviolet to visible light, to infrared, to terahertz radiation.
Abstract: A porous membrane comprising stacked layers of nanosheets, each nanosheet comprising one to three atomic layers of a 2D material comprising or consisting of one or more transition metal dichalcogenides is provided. The nanosheets have pores and the membrane comprises a network of water permeation pathways including through-pathways formed by the pores, horizontal pathways formed by gaps between the layers, and vertical pathways formed by gaps between adjacent nanosheets and stacking defects between the layers. Also provided is a method for making the membrane.
Abstract: Systems, devices, and methods for access point discovery in a wireless network are provided. An access point device embeds into a preamble of a transmission packet discovery information including modifications determined by passing in-phase quadrature (IQ) symbols through a finite impulse response (FIR) filter to introduce a phase shift in selected ones of the IQ symbols. The phase shifts are encoded into bits in selected ones of a plurality of subcarriers, bounded by a maximum phase shift and a maximum number of the subcarriers to limit the packet error rate. A convolutional neural network can learn channel state and other information to determine the maximum phase shift and number of subcarriers. A client device can select from among a plurality of modified transmission packets to send a discovery request.
Abstract: Embodiments of the present invention relate to a novel compound of Formula (I) or stereoisomer, a tautomer, or a pharmaceutically acceptable salt thereof, for use in treatment of infection caused by Gram-negative bacteria.
Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer.
Type:
Grant
Filed:
December 19, 2018
Date of Patent:
November 15, 2022
Assignees:
TargaGenix, Inc., The Research Foundation for The State University of New York, Northeastern University
Inventors:
James E. Egan, Mansoor Amiji, Iwao Ojima
Abstract: Embodiments provide functionality for identifying joints and limbs in images. An embodiment extracts features from an image to generate feature maps and, in turn, processes the feature maps using a single convolutional neural network trained based on a target model that includes joints and limbs. The processing generates both a directionless joint confidence map indicating confidence with which pixels in the image depict one or more joints and a directionless limb confidence map indicating confidence with which the pixels in the image depict one or more limbs between adjacent joints of the one or more joints, wherein adjacency of joints is provided by the target model. To continue, indications of the one or more joints and the one or more limbs in the image are generated using the directionless joint confidence map, the directionless limb confidence map, and the target model. Embodiments can be deployed on mobile and embedded systems.
Abstract: The presently disclosed embodiments generally relate to systems, devices, and methods for sensing and charging of electronic devices using coils. In some embodiments, the presently disclosed system can include a pad, a charging foot, and a backpack. The pad can include one or more nested coils therein that can sense one or more corresponding receiver coils of an unmanned aerial vehicles (UAV) that landed thereon. The nested coils of the pad can provide charging energy to the UAV independent of the location along the pad in which the UAV landed, and no precise alignment between the receiver coils and the charging coils is required. The charging foot can be attached to one or more legs of the UAV, and can include a receiver coil and circuitry to regulate energy received by the coil to a charging voltage level that can be provided to the battery.
Abstract: Cosmetic and dermatological compositions, including color changing compositions, are provided which typically include a plurality of synthetic particles having a size in the micrometer or nanometer range. Each synthetic particle typically includes one or more aggregates of a pigment selected from phenoxazone, phenoxazine, and a derivate or precursor thereof, and a stabilizing material which has a refractive index larger than 1.45; the aggregates having a size larger than about 100 nm and the composition being biodegradable and biocompatible.
Type:
Grant
Filed:
September 25, 2018
Date of Patent:
October 11, 2022
Assignee:
Northeastern University
Inventors:
Leila Deravi, Camille A. Martin, Amrita Kumar
Abstract: The present disclosure relates to a method for detecting a compound, comprising the steps of: contacting a compound with a solid analytical surface (SAS), thereby forming an SAS with an absorbed compound; contacting the SAS with the absorbed compound with a mass tag, wherein the mass tag reacts with the absorbed compound, thereby forming an SAS with a covalently mass-tagged absorbed compound; and detecting the covalently mass-tagged absorbed compound by mass spectrometry. Also disclosed is a device for collecting breath aerosol, comprising a card or an envelope, wherein the card or the envelope comprise a tab, wherein the tab is a SAS.
Type:
Grant
Filed:
June 6, 2019
Date of Patent:
September 27, 2022
Assignee:
Northeastern University
Inventors:
Pushkar Kulkarni, Poguang Wang, Roger W. Giese
Abstract: Pink noise analysis, along with unique properties of the photovoltaic (PV) operating point of both the instantaneous current and voltage signal, is used to distinguish arc faults from other noisy loads or PV degradations.
Type:
Application
Filed:
March 18, 2022
Publication date:
September 22, 2022
Applicants:
MERSEN USA EP CORP., Northeastern University
Abstract: A soft neural interface connector apparatus includes a PCB having a two-dimensional array of solder balls, a transparent top board, a cushioning layer on one side of the transparent top board, and a soft neural interface including a flexible and/or stretchable microelectrode array (MEA) through which neural signals are obtained or delivered. The MEA includes a two-dimensional array of contact pads corresponding to the array of solder balls. The PCB, the transparent top board, the cushioning layer, and the MEA are stacked together such that the MEA is between the cushioning layer and the PCB, and the contact pads are aligned with and in electrical contact with associated solder balls. A magnetic connector system having at least one magnetic connector component on the transparent top board is magnetically connected with at least one magnetic connector component on the PCB to press the contact pads and associated solder balls together.
Type:
Grant
Filed:
November 24, 2020
Date of Patent:
August 16, 2022
Assignee:
Northeastern University
Inventors:
Hui Fang, Yi Qiang, Xun Han, Kyung Jin Seo
Abstract: Disclosed is a composite material, comprising a polymer, a plurality of metal nanoparticles, and a surface-modifying agent (e.g., nanocellulose). Also disclosed is a method for shielding a subject from electromagnetic radiation, comprising placing one or more composite materials between the subject and a source of electromagnetic radiation, thereby reducing a dose of electromagnetic radiation received by the subject.
Abstract: Divergence of state estimation solutions for multi-area power grids typically occurs due to a single anomaly in the measurement set or network model, yet will cause failure of the state estimator to provide the solution for the entire system. Disclosed herein are methods and systems that allow detection, identification and isolation of the anomaly during the state estimation solution so that a large percentage of the system states can still be estimated, while isolating the anomaly that is causing the divergence for the estimator.