Patents Assigned to State University
  • MOLDED POMACE PULP PRODUCTS AND METHODS
    Publication number: 20180119361
    Abstract: Composite molded pulp products prepared from fruit or vegetable-based pomace, fibrous paper-based materials, and cellulose nanofiber and methods for preparing the same are provided.
    Type: Application
    Filed: November 3, 2017
    Publication date: May 3, 2018
    Applicant: Oregon State University
    Inventors: Yanyun Zhao, Jooyeoun Jung, John Simonsen
  • RING-OPENING POLYMERIZATION METHODS AND RECYCLABLE BIORENEWABLE POLYESTERS
    Publication number: 20180118880
    Abstract: The invention provides polymers of Formulas I-III, such as polyesters and unsaturated polyesters, and crosslinked and copolymerized polymers thereof. The invention also provides methods to catalytically ring-open five-membered rings such lactones, lactams, and thiolactones, as via ring-opening polymerization. The polymerization products are recyclable and can be depolymerized back to their monomer form via thermolysis and acid or base catalysis.
    Type: Application
    Filed: April 11, 2016
    Publication date: May 3, 2018
    Applicant: Colorado State University Research Foundation
    Inventors: Eugene Y. CHEN, Miao HONG, Xiaoyan TANG
  • QUADRUPLE BUTTERFLY COIL
    Publication number: 20180117352
    Abstract: Provided herein are embodiments of a Quadruple Butterfly Coil (QBC) configuration having enhanced focality for stimulation of specific areas of a brain for therapeutic treatment. Finite element simulations were conducted for the QBC, the QBC with a single shield, and the QBC with a double shield. The stimulation profiles for these coil configurations were assessed with 50 anatomically realistic MRI derived head models. The coils were positioned on the vertex and the scalp over the dorsolateral prefrontal cortex to stimulate the brain. Computer modeling of the coils was performed to determine volume of stimulation, maximum electric field, location of maximum electric field, and area of stimulation across all 50 head models for both coils.
    Type: Application
    Filed: October 26, 2017
    Publication date: May 3, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Priyam Rastogi, Erik Gordon Lee, Magundappa Ravi L. Hadimani, David C. Jiles
  • SYSTEMS AND METHODS FOR AN AUTOMATED, NEAR REAL-TIME, AND MOBILE IDENTIFICATION AND LOCALIZATION APPROACH WITH A COMBINATION OF BATTERY-LESS IDENTIFICATION MARKING TECHNOLOGIES AND PSEUDO RANGE-FREE LOCALIZATION ALGORITHMS
    Publication number: 20180121777
    Abstract: Embodiments of an automated and mobile identification and localization system and method for tracking both the final (stationary) and intermediate (transient) location of non-bulk resources and components are disclosed.
    Type: Application
    Filed: April 22, 2016
    Publication date: May 3, 2018
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventor: David Grau Torrent
  • Photoremovable protecting groups and uses thereof
    Patent number: 9957498
    Abstract: The invention relates to a method for photoreleasing a moiety G from a compound of the formula A-G. The methods of the present invention comprise irradiating a composition comprising the compound of the formula A-G at a wavelength of >500 nm, so as to photorelease the moiety G from the moiety A; wherein the moiety A comprises a chromophore and the moiety G comprises an organic compound.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: May 1, 2018
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Arthur Henry Winter, Christie Lynn Beck, Kaitlyn Marie Mahoney, Toshia Renee Albright, Pratik Pran Goswami
  • Contrast agents, methods for preparing contrast agents, and methods of imaging
    Patent number: 9956304
    Abstract: Provided is a protein contrast agent for enhancing an MRI image and comprising a polypeptide having a conformation presenting at least five oxygen atoms positioned to chelate at least one paramagnetic metal ion such as Gd3+, each oxygen atom being between about 2 angstrom units and about 5 angstrom units from the metal ion; the metal ion has at least one water molecule electrostatically interacting a distance of less than about 10 angstrom units a target-specific moiety conjugated thereto, at least one polyethylene glycol molecule, and a paramagnetic metal ion. Also provided is a method of obtaining an enhanced MRI image using the protein contrast agent to a T2/T1 or T1/T2 intensity ratio of the MRI image; and (d) obtaining an image of the T2/T1 or T1/T2 intensity ratio.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: May 1, 2018
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Jenny Jie Yang, Zhiren Liu, Shunyi Li, Yubin Zhou, Jie Jiang, Shenghui Xue, Jingjuan Qiao, Lixia Wei
  • SecA inhibitors and methods of making and using thereof
    Patent number: 9957247
    Abstract: Inhibitors of SecA, and methods of making and using thereof, are described herein. The compounds described herein can be used to treat or prevent microbial infections, such as bacterial infections.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: May 1, 2018
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Binghe Wang, Phang-Cheng Tai, Jinshan Jin, Yinghsin Hsieh, Ying-Ju Ritter, Jianmei Cui, Arpana S. Chaudhary, Chaofeng Dai, Krishna Damera, Weixuan Chen
  • Neuroprotection by mitochondria-targeted metformin
    Patent number: 9956233
    Abstract: The present invention provides modified metformin compounds, particularly mito-metformin compounds, and pharmaceutical compositions thereof. Methods of using the compounds to provide neuroprotection and in the treatment and/or prevention of neurodegenerative diseases are also described.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: May 1, 2018
    Assignees: Iowa State University Research Foundation, Inc., The Medical College of Wisconsin, Inc.
    Inventors: Anumantha Kanthasamy, Balaraman Kalyanaraman
  • Laser assisted SiC growth on silicon
    Patent number: 9960037
    Abstract: A method for forming a compound on a substrate is provided. The method includes depositing a composition onto a surface of a substrate; illuminating the composition and the substrate with pulsed energy; melting the substrate and decomposing the composition simultaneously; and forming a compound on the substrate. A first component of the compound is derived from the substrate and a second component of the compound is derived from the composition.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: May 1, 2018
    Assignee: Board Of Trustees Of Michigan State University
    Inventors: Premjeet Chahal, Tim Hogan, Amanpreet Kaur
  • Near-infrared fluorescent dyes with large stokes shifts
    Patent number: 9958451
    Abstract: Embodiments of near-infrared (NIR) dyes are disclosed, along with methods and kits for detecting analytes with the NIR dyes. The NIR dyes have a structure according to the general structure At least one of R1/R2, R2/R3, R3/R4, R5/R6, R6/R7, and/or R7/R8 together forms a substituted or unsubstituted cycloalkyl or aryl.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: May 1, 2018
    Assignee: Portland State University
    Inventors: Robert Michael Strongin, Martha Sibrian-Vazquez, Jorge Omar Escobedo-Cordova, Mark Allen Lowry
  • Multi-tier caching
    Patent number: 9959279
    Abstract: A method for maintaining an index in multi-tier data structure includes providing a plurality of a storage devices forming the multi-tier data structure, caching an index of key-value pairs across the multi-tier data structure, wherein each of the key-value pairs includes a key, and one of a data value and a data pointer, the key-value pairs stored in the multi-tier data structure, providing a journal for interfacing with the multi-tier data structure, providing a plurality of zone allocators recording which zones of the multi-tier data structure are in used, and providing a plurality of zone managers for controlling access to cache lines of the multi-tier data structure through the journal and zone allocators, wherein each zone manager maintains a header object pointing to data to be stored in an allocated zone.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: May 1, 2018
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Shrikar Archak, Sagar Dixit, Richard P. Spillane, Erez Zadok
  • Portable contact angle measuring device
    Patent number: 9958264
    Abstract: In some embodiments, a system and/or method may include assessing surface cleanliness. In some embodiments, the system may include a dispensing device. The dispensing device may dispense, during use, a liquid on a surface forming a drop. In some embodiments, the system may include a stage. The stage may support, during use, a digital imaging device above the drop positioned on the surface. In some embodiments, the system may include a light emitter. The light emitter may emit, during use, a beam of light substantially parallel to the surface at the drop. In some embodiments, the system may include an adjustable support coupled to the stage. The adjustable support may adjust, during use, an angle of the stage relative to the surface. In some embodiments, the system is configured to determine a contact angle of the drop relative to the surface.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: May 1, 2018
    Assignee: Sam Houston State University
    Inventor: Darren L. Williams
  • Methods and systems for fast imprinting of nanometer scale features in a workpiece
    Patent number: 9956720
    Abstract: The subject matter described herein relates to methods and systems for fast imprinting of nanometer scale features in a workpiece. According to one aspect, a system for producing nanometer scale features in a workpiece is disclosed. The system includes a die having a surface with at least one nanometer scale feature located thereon. A first actuator moves the die with respect to the workpiece such that the at least one nanometer scale feature impacts the workpiece and imprints a corresponding at least one nanometer scale feature in the workpiece.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: May 1, 2018
    Assignee: North Carolina State University
    Inventors: Thomas A. Dow, Erik Zdanowicz, Alexander Sohn, Ron Scattergood, William John Nowak, Jr.
  • Isomerization of muconic acid
    Patent number: 9957218
    Abstract: Various embodiments disclosed relate to isomerization of muconic acid. In various embodiments, the present invention provides a method of forming trans,trans-muconic acid. The method includes heating a starting material composition to form a product composition including trans,trans-muconic acid. The starting material composition includes cis,cis-muconic acid, cis,trans-muconic acid, or a combination thereof. The starting material composition also includes an electrophilic compound, an organic solvent, or a combination thereof.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: May 1, 2018
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Jean-Philippe Tessonnier, Jack M. Carraher, Toni Pfennig, Brent Shanks
  • System and method for automatic pulmonary embolism detection
    Patent number: 9959615
    Abstract: A system and method for detecting pulmonary embolisms in a subject's vasculature are provided. In some aspects, the method includes acquiring a set of images representing a vasculature of the subject, and analyzing the set of images to identify pulmonary embolism candidates associated with the vasculature. The method also includes generating, for identified pulmonary embolism candidates, image patches based on a vessel-aligned image representation, and applying a set of convolutional neural networks to the generated image patches to identify pulmonary embolisms. The method further includes generating a report indicating identified pulmonary embolisms.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: May 1, 2018
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Jianming Liang, Nima Tajbakhsh
  • Microscope sample preparation device
    Patent number: 9958362
    Abstract: A sample preparation device for electron microscopy (EM) that is configured to eliminate user-to-user variations and environment contaminations, which are often present in the conventional method of sample preparation. The device not only provides a means for evenly and reproducibly delivering a fluid or sample to an EM grid, but also provides a means for sealing the EM grid in an air-tight chamber and delivering air-sensitive samples to the EM grid. The platform may comprise readily fabricated glass chips with features integrated to preserve the integrity of the sample grid and to facilitate its extraction. The methods may eliminate the element of user dependent variability and thus improve the throughput, reproducibility and translation of these methods.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: May 1, 2018
    Assignee: The Florida State University Research Foundation, Inc.
    Inventors: Michael G. Roper, Nikita Mukhitov, Scott Stagg, John Spear
  • Multifunctional radical quenchers
    Patent number: 9957214
    Abstract: The invention provides a compound of formula (I): [insert formula (I)] wherein X, Y, and R1-R4 have any of the values defined in the specification, and salts thereof, as well as compositions comprising the compounds or salts. The compounds are useful for treating diseases associated with impaired mitochondrial function in an animal.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: May 1, 2018
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Manikandadas Mathilakathu Madathil, Omar Khdour, Sidney Hecht
  • Attenuation of human respiratory syncytial virus by genome scale codon-pair deoptimization
    Patent number: 9957486
    Abstract: Described herein are RSV polynucleotide sequences that make use of multiple codons that are containing silent nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce a numerous synonymous codons into the genome. Due to the large number of defects involved, the attenuated viruses disclosed herein provide a means of producing attenuated, live vaccines against RSV.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: May 1, 2018
    Assignees: The United States of America, as represented by the Secretary, Dept. of Health and Human Services, The Research Foundation For the State University of New York
    Inventors: Peter L. Collins, Cyril Le Nouën, Linda G. Brock, Ursula J. Buchholz, Joshua Marc DiNapoli, Steffen Mueller, Eckard Wimmer
  • Wearable head-mounted, glass-style computing devices with EOG acquisition and analysis for human-computer interfaces
    Patent number: 9955895
    Abstract: A apparatus for detecting electrooculograph (EOG) signals, comprising: a pair of temple pieces connected to a bridging structure; at least one electrode on each temple piece configured to contact the skin at the temple, and to receive an EOG signal from a proximate orbital socket; a reference electrode displaced from each temple; and a processor configured to process signals from the sensors to detect saccade movements of the eyes. A wavelet-based algorithm permits analysis and coding of the saccade movements.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: May 1, 2018
    Assignee: The Research Foundation for the State University of New York
    Inventors: Zhanpeng Jin, Sarah Laszlo
  • Fibroblast growth factor mutants having improved functional half-life and methods of their use
    Patent number: 9957310
    Abstract: Mutant fibroblast growth factor (FGF) proteins having a polypeptide sequence with a high sequence identity to proteins encoded by members of the Fgf-1 subfamily of genes from a mammalian species, such as human, and with a specific amino acid substitution of an alanine at a position corresponding to amino acid position 66 of human FGF-1 with a cysteine and/or a specific amino acid substitution of a phenylalanine at a position corresponding to amino acid position 132 of human FGF-1 with a tryptophan (based on the 140 amino acid numbering scheme of human FGF-1) are provided. Other amino acid mutations or substitutions may be combined. Polynucleotide sequences encoding the mutant FGF proteins and host cells containing such polynucleotide sequences are provided. Methods of administering a mutant FGF protein to an individual to treat an ischemic condition or disease or a wound or tissue injury are also provided.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: May 1, 2018
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Michael Blaber, Jihun Lee