Abstract: A device for absolute distance measurement includes a first tunable light source for emitting a first wavelength light of a first tunable frequency modulated by a first modulating frequency and a second light source for emitting a second wavelength light of a second frequency modulated by a second modulating frequency. An optical coupler couples the first wavelength light and the second wavelength light into an interferometer cavity. An interferometer detector provides an interference measurement signal based on a detected interference pattern. A demodulator unit generates a first demodulation signal based on the interference measurement signal by demodulation with the first modulating frequency and a second demodulation signal based on the interference measurement signal by demodulation with the second modulating frequency. A computation unit computes an absolute distance by evaluating the first demodulation signal acquired during a sweep of the first tunable frequency and the second demodulation signal.

Abstract: A device for moving a nonlinear crystal or a saturable absorber in two dimensions includes a first and a second piezo unit, each having a corresponding carrier, piezo driver, and carriage moveable by the piezo driver at incremental steps along a linear path with respect to the carrier between a first and a second end location, in which the linear paths of the first piezo unit and the second piezo unit are orthogonal. The nonlinear crystal/saturable absorber is fastenable on the carriage of the first piezo unit and the carrier of the first piezo unit is fastened on the carriage of the second piezo unit. The device further includes stops that define the carriage end locations, an end location detection configured to detect the carriages at their respective end locations, and a counting unit configured to count the steps covered during the moving of the carriage.

Abstract: A secure housing for a portable computer, which has a screen, operating keys and at least one connector, can be transferred from an open state to a closed state. In order to protect the computer and the data stored thereon, the secure housing can be locked in the closed state and conceals at least one operating key of the computer while the screen is exposed.

Abstract: A device for controlling the anesthetization of an animal to be slaughtered. The device includes a stimulation unit via which a stimulation stimulus is given to the animal. The device includes an image capturing unit that has an image capturing range. The image capturing unit is constructed as a 3D-camera. One part of a surface of the animal is optically detected in the image capturing range and range pixels are collected in the area of the surface. The range pixels are provided and transmitted as pixel data. An evaluation unit is connected to the image capturing unit and collects the pixel data provided by the image capturing unit. The evaluation unit determines an active movement of the animal from the detected pixel data and provides and transmits the control result in the event of a determined movement of the animal.

Abstract: The invention relates to a pharmaceutical composition in the form of a system in film form for transmucosal administration of steroid hormones. An administration system for steroid hormones which dissolves in the mouth and which releases with a high bioavailability is disclosed. The administration system in film form dissolves in the mouth preferably in a period of less than 30 min, and the steroid hormone entering the bloodstream transmucosally from the administration system leads to a rapid rise in the concentration in the blood. It is thus possible to achieve a maximum concentration of this steroid hormone in the blood in a period of less than 60 min after administration.

Abstract: A control release and abuse-resistant opiate drug delivery oral wafer or edible oral film dosage to treat pain and substance abuse is provided. The drug delivery oral wafer or edible oral film dosage includes a controlled release layer containing enteric-release beads dispersed in a polymer matrix. The enteric-release beads are formed from a therapeutic amount of an opioid agonist and/or pharmaceutically acceptable salt thereof and a sub-therapeutic amount of opioid antagonist and/or pharmaceutically acceptable salt thereof coated or encapsulated in an enteric-release polymer. The controlled release polymer matrix dissolves or disintegrates following administration or consumption of the oral wafer or edible oral film, releasing the enteric-release beads to be swallowed, with subsequent absorption of the active ingredients within the patient's intestines.

Abstract: A transdermal therapeutic system for administering at least one active pharmaceutical ingredient, including a polymer-based layer which is remote from the skin with a rate of application of at least 80 g/m2, and an adhesive skin-contact layer which is adjacent to the polymer-based layer remote from the skin and is based on acrylate copolymers with a rate of application of not more than 50 g/m2. The at least one active pharmaceutical ingredient is present in both the polymer-based layer remote from the skin and the skin-contact layer.

Abstract: The invention relates to the use of semi-fluorinated alkanes, in particular mixed with ethanol, as solubilising agents, permeation promoters and/or enhancers for lipophilic and/or poorly skin-permeable pharmaceutical agents that are administered via a transdermal therapeutic system (TTS), and to corresponding TTSs containing such substances.

Abstract: A control release and abuse-resistant opiate drug delivery oral wafer or edible oral film dosage to treat pain and substance abuse is provided. The drug delivery oral wafer or edible oral film dosage includes a controlled release layer containing enteric-release beads dispersed in a polymer matrix. The enteric-release beads are formed from a therapeutic amount of an opioid agonist and/or pharmaceutically acceptable salt thereof and a sub-therapeutic amount of opioid antagonist and/or pharmaceutically acceptable salt thereof coated or encapsulated in an enteric-release polymer. The controlled release polymer matrix dissolves or disintegrates following administration or consumption of the oral wafer or edible oral film, releasing the enteric-release beads to be swallowed, with subsequent absorption of the active ingredients within the patient's intestines.

Abstract: The invention relates to a gearshifting device (1), which is intended for a transmission and comprises a selector lever (2) that can be moved in such a manner that different shift positions (P, R, N, D, S, M+, M?) can be selected in at least two gearshift gates (3, 4) and that it is possible to shift between one of the gearshift gates (3, 4) and the at least one other gearshift gate (4, 3), and comprises at least one lock (5), which is used to block the traversing path of the selector lever (2) with respect to one of the gearshift gates (3, 4), in order to shift from one of the shift positions (P, R, N, D, S) into another of the shift positions (P, R, N, D, S).

Abstract: Methods and apparatus for cross flow process reactors are disclosed. A disclosed example includes a process chamber having an inlet and an outlet to allow a flow of fluid to flow therethrough and a plurality of trays disposed within the process chamber, and containing bulk material to treat the fluid. The example apparatus also includes a flow director to divide the flow into a plurality of partial flow streams, where each partial flow stream is to be directed towards at least one tray of the plurality of trays.

Abstract: The invention relates to a method for producing an ultrapure, aqueous, long-term- and storage-stable, and thus transportable chlorine dioxide solution, comprising the steps of providing chlorite, providing peroxodisulfate, and combining chlorite and peroxodisulfate in an aqueous system and in a molar ratio of peroxodisulfate to chlorite [S2O82?]/[ClO2?] of greater than 1, forming the aqueous chlorine dioxide solution, wherein no additional buffer is added to produce the aqueous chlorine dioxide solution. The invention further relates to a corresponding chlorine dioxide solution, to the use of said chlorine dioxide solution, and to a device for producing the chlorine dioxide solution.

Abstract: A selector device for a motor vehicle transmission has an actuating lever (1) transferable into a first shift gate, in which it is coupled mechanically to a transmission component (2) for actuating a selector control cable (23), or into a second shift gate which is decoupled from the transmission component (2). The transmission component (2) is mounted movably, and a locking means (11) is configured as a spring element that is received in a locking receptacle (16) when the actuating lever (1) is situated in the second shift gate. The locking receptacle (16) has an end centering means (25), in which the locking means (11) is received with a shaped part (21) when the actuating lever (1) is situated in the second shift gate, and has a relieving centering means (26) which tapers conically. The shaped part (21) is configured to be received in a positively locking manner by the relieving centering means (26) during move out of the end centering means (25).

Abstract: Transdermal therapeutic system for the transdermal administration of rotigotine containing an therapeutically effective amount of rotigotine base in a self-adhesive layer structure, comprising A) a backing layer, and B) a rotigotine-containing biphasic layer, the bi phasic layer having a) an outer phase having a composition comprising 75% to 100% of a polymer or a polymer mixture, and b) an inner phase having a composition comprising rotigotine base, wherein the inner phase forms dispersed deposits in the outer phase, and wherein the inner phase comprises i. rotigotine base, and ii.

Abstract: The invention relates to transdermal therapeutic systems (TTS) comprising a backing, a reservoir layer containing at least one pharmaceutical active ingredient, and an adhesive. Said transdermal therapeutic systems are characterised in that they are able to continuously adhere to the surface of the skin over a long period of time. During said long period of time, a) there is at least one time interval during which the TTS adhering to the surface of the skin is intensively exposed to water, and b) the active ingredient is transdermally released. The invention also relates to a method for the continuous transdermal release of at least one pharmaceutical active ingredient over a long period of time.

Abstract: The present invention relates to a seat for a vehicle, particularly an aircraft, having a visual playback device integrated in a surface of the seat. A base firmly connected to the seat is arranged in the surface of the seat. Said visual playback device is releasably attached to the base by means of a holder adapted to the visual playback device and the base.

Abstract: A container formed of a blank (2) consisting of first, second, third, fourth and fifth panels (4, 6, 8, 10, 12), respectively. The first, second, third, fourth and fifth panels (4, 6, 8, 10, 12) include respective top sealing sub-panels (14, 16, 18, 20, 22), of an outwardly bowed form bounded inwardly by respective score lines (15, 17, 19, 21, 23). The first, second, third, fourth and fifth panels (4, 6, 8, 10, 12) also include respective bottom sealing sub-panels (24, 26, 28, 32, 34) of a per se known form. The first and third panels (4, 8) also include respective intermediate panels (34,38) which are each uninterrupted by score lines, except that one intermediate sub-panel (38) is formed with a through hole (40) for receiving a pour spout fitment. The second and fourth panels (6, 10) include respective intermediate sub-panels (36, 40) which are divided by score lines into respective sub-sub-panels (42, 44), identically as between the sub-panels (36, 40).

Abstract: A method for producing a tightly sealed bag packaging and to a tightly sealed bag packaging having at least one perforation and a receiving area surrounded by a plate-shaped edge region for the inert packaging of a product containing active ingredients, wherein the bag packaging comprises cover films or cover film segments bounding the receiving area and forming the edge region. The cover films or cover film segments are each provided with a channel system having at least one channel. The channel system crosses the part of the cover film or the cover film segment covering the receiving area. At one end, each channel is provided with a branching into two channel branches, Furthermore, a slit is arranged between the two channel branches, interrupting a peripheral edge of the bag packaging.

Abstract: The invention relates to a retaining device (10) comprising a) a holder (2) that includes a receptacle (1), b) a spring-biased pin (4) which is guided so as to be longitudinally movable in the receptacle (1) of the holder (2) and which includes a pin head (3) that protrudes from the receptacle (1) of the holder (2), c) a centering mechanism (5) which is stationarily arranged on the pin (4) and is provided with a restoring force within the receptacle (1) of the holder (2), said restoring force being directed against the holder (2).