Abstract: A device for protecting tissue when treating an eye using a laser beam generated by a laser system and deflected by a scanner system comprises an eye model, a control data module and a processor. The eye model comprises eye data which define dimensions and locations of eye structures. The control data module is configured to register control data which define beam parameters of the laser beam and a scanning pattern for the laser beam. The processor is configured to simulate by computation a light spot moving on or in an eye structure on the basis of the eye data and the control data, to add up, for a plurality of measurement points of the eye structure and continuously, a beam dose emitted at the relevant measurement point by the moving light spot and to generate an emergency signal if a dose limit Dmax is exceeded at one of the measurement points.

Abstract: An ophthalmological patient interface apparatus (4), having a coupling apparatus (41) for mechanically coupling to an application head (3) of an ophthalmological laser system (10), comprises a lens-element system (44) which is arranged between the eye (2) and the application head (3) in the state coupled to the application head (3) during the treatment of an eye (2), said lens-element system being coupled into the beam path from the projection lens (30) to the eye (2). The lens-element system (44) is configured to image a first focal area (B) of the projection lens (30) disposed upstream of the lens-element system (44) in the beam path onto a second focal area (B*) in the eye (2) disposed downstream of the lens-element system (44) in the beam path, in such a way that a laser beam (L) focussed onto the first focal area (B) by the projection lens (30) causes tissue processing in the second focal area (B*) in the eye (2).

Abstract: A medical active substance patch comprising a matrix of monolayer or multilayer configuration with at least one active substance-containing layer and comprising a backing layer connected with the matrix. The active substance patch is transparent or at least translucent, and in the state of having been applied to the skin of a first person, the patch has a lightness colour value L1 at a place of the skin covered by the patch which is not less than 50% and not more than 200% of a lightness colour value L2, L2 being the lightness value of the region of the skin of the same person which surrounds the applied patch. The same is true of the skin of a second or any other person, provided that for all the persons mentioned L2 is in the range from 5° to 100°, namely from 20° to 90°.

Abstract: A transparent or translucent medical active substance patch is provided that includes a matrix of monolayer or multilayer configuration with at least one active substance-containing layer contained therein and a backing layer connected with the matrix. The patch, having been applied to the skin of a first person, has a lightness color value L1 at a place of the skin covered by the patch which is not less than 50% and not more than 200% of a lightness color value L2, with L2 being the lightness value of the region of skin of the same person which surrounds the applied patch, with the same being true of the skin of a second or any other person, provided that for all the persons mentioned, the L2 of their respective skin is in the range from 5° to 100°, especially in the range from 20° to 90°.

Abstract: The invention relates to a method for protecting a computer program from being influenced by an invasive program or by manipulation software for manipulating computer programs on a computer system comprising a processor, a main storage unit, and a storage medium. The method involves the Kerckhoffs's principle such that the protected computer program is freely accessible and can be read by an invasive program or manipulation software. Parts of the protected computer program are provided multiple times in the program code of the protected computer program as a result of the specialization of the computer program. Parts of the computer program are encrypted in order to prevent a statistical analysis of the computer program without the processor running the computer program, wherein a key which is required to decrypt the encrypted parts of the computer program is stored in a protected key storage unit which communicates with the computer.

Abstract: An installation has a process chamber defining an inner space having a tunnel-like form defining a receiving region for workpieces. The process chamber has a portal for the supply or discharge of workpieces and has a device for introducing gaseous fluid into the inner space. The device has a nozzle for producing a fluid stream curtain between the portal and the receiving region. A device supplies fresh air introduced into the receiving region at a side of the fluid stream curtain facing away from the portal. The installation has a pivotable guide contour projecting into the inner space and the nozzle or aperture is in the form of a slot which supplies the gaseous fluid to the inner space via the ceiling with a flow direction oblique relative to the floor. The gaseous fluid supplied via the nozzle to the inner space is guided on the guide contour.

Abstract: The present invention relates to a transdermal therapeutic system, preferably a transdermal patch, having an active ingredient-containing matrix formed substantially of a water-insoluble base material, such as rubber and synthetic polymers, into which is incorporated water-soluble and/or water-swellable inclusion bodies, e.g. inclusion bodies formed from polyvinyl alcohol or polyethylene glycol, that further include micronized or nanoscale active ingredient particles.

Abstract: In order to provide a filter system for separating off contaminants from a stream of untreated gas that contains contaminants that is of simple construction and is operable efficiently, it is proposed that the filter system should include the following: a base construction through which the stream of untreated gas is guidable and which includes at least one filter module receptacle for receiving at least one filter module, and at least one filter module which is selectively arrangeable on and/or in the at least one filter module receptacle and/or removable therefrom, wherein the at least one filter module includes a plurality of filter element receptacles for receiving a plurality of mutually independent filter elements.

Abstract: In order to provide a treatment installation for treating workpieces that is of simple construction and enables optimised workpiece treatment, it is proposed that the treatment installation should include a treatment chamber and a conveying device, by means of which the workpieces are suppliable to the treatment chamber, are removable from the treatment chamber, and/or are conveyable through the treatment chamber in a conveying direction.

Abstract: A method of inverting the phase arrangement of the silicone phase and the acrylic phase in a silicone acrylic hybrid composition, the silicone acrylic hybrid composition comprising: a) a silicone acrylic hybrid pressure sensitive adhesive, and b) a solvent, wherein the phase arrangement of the silicone phase and the acrylic phase in the initial silicone acrylic hybrid composition forming a continuous external phase and a discontinuous internal phase is determined by the solvent, comprising the step of adding an activator to the silicone acrylic hybrid composition, wherein the activator a) is liquid at 20° C. and 1013 mbar, b) has a boiling point which is higher than the boiling point of the solvent and/or has a vapor pressure at 20° C.

Abstract: An ophthalmic device for treating eye tissue using laser pulses comprises a projection optical unit for focused projection of the laser pulses and a scanning device, with a movable mirror, arranged downstream from the projection optical unit, for deflecting the laser pulses projected by the projection optical unit in at least one deflection direction. The ophthalmic device moreover comprises an optical correction element arranged downstream of the scanning device, which correction element is configured to image, in a focused manner, the laser pulses deflected by the scanning device on an intended treatment area in the eye tissue. The optical correction element renders it possible to therefore correct image field curvatures caused by the scanning device arranged downstream from the projection optical unit and, for example, image the deflected laser pulses in focus onto a plane.

Abstract: The invention relates to a transdermal therapeutic system on the basis of polysiloxane which contains microreservoirs filled with an active substance and one ambiphilic solvent.

Abstract: An ophthalmic device for treating eye tissue comprises a light source for generating laser pulses, a light projector for focused projection of the laser pulses into the eye tissue and an interferometric measurement system for measuring eye structures. The ophthalmic device comprises an optical element which is movable in relation to the light source and provided for preventing a change in the path length difference between measurement and reference arms of the interferometric measurement system resulting from a change in the length of the light-transmission path caused by a movement of the light projector relative to the light source. The interferometric measurement system enables a flexible measurement of the eye structures before, during and after the treatment, wherein measurement errors in the interferometric measurement system resulting from length changes in the light-transmission path are avoided, which are caused by movements of the light projector relative to the light source.

Abstract: The invention relates to systems formed from closed liquid-tight packaging and a preferably dimensionally stable aqueous composition which is sealed therein and which, upon activation, releases a liquid phase essentially composed of water in a time-delayed manner. The invention further relates to methods for manufacturing such systems and the use thereof during the production of self-decomposing transdermal therapeutic systems (TTS).

Abstract: Dispensing of hot water having an adjustable temperature by way of a water outlet fitting that can be installed on a sink. This is achieved by a continuous flow heater and a measured value sensor arranged in a water inlet of the water outlet fitting as the hot water heater. The measured value sensor detects a measurement variable with regard to water flowing through the continuous flow heater (10). The water dispensing device has a control unit, which is designed to regulate a flow rate through the continuous flow heater as a function of measured values of the measured value sensor in order to adjust the temperature of the hot water.

Abstract: The invention relates to a transdermal therapeutic system (TTS) for delivering pharmaceutical active ingredients. The TTS includes a cover layer and at least one active-ingredient-containing carrier material. At least one retaining element is located between the active-ingredient-containing carrier material and the cover layer, with the retaining element fixing the active-ingredient-containing carrier material onto the cover layer. The invention further relates to a method for fastening an active-ingredient-containing carrier material to a cover layer of a TTS in the presence of hook-and-loop strip segments and the use of a hook-and-loop strip in transdermal or iontophoretic administration of pharmaceutical or therapeutic active ingredients to patients.

Abstract: The invention relates to a transdermal therapeutic system (TTS), which is suited for the administration of a peptide to a patient through skin treated with ablation. The transdermal therapeutic system includes a back layer and an active substance-containing layer that contains at least one peptide and a carrier substance, preferably as a textile web material.

Abstract: The present disclosure relates to a diffuser for a radial compressor.

Abstract: The present invention relates to a compressor assembly for a turbocharger. The compressor assembly may comprise a spiral housing with a flow channel which is designed to convey a fluid which can be sucked up from outside the compressor assembly, a compressor outlet flange which is fluidically connected to the spiral housing via the flow channel, and an injection device designed to introduce a fluid from outside the compressor assembly into the flow channel, wherein the injection device is arranged outside the flow channel of the spiral housing.

Abstract: A carton blank for forming a carton, and comprising a row of first, second, third and fourth substantially four-edged panels, each panel having substantially the same width and comprising a side wall part, a top closure obturating part and a top sealing fin part, one of said panels from an outermost boundary of the side wall part to an outermost boundary of the top closure obturating part being substantially free from any lateral line of weakness, the obturating part of said one of said panels including a loop of weakness.