Abstract: The present invention provides transdermal therapeutic systems for dispensing a pharmaceutical product, in particular a pharmaceutical product with a low tendency to spontaneously crystallize. The matrix layer or at least one of the matrix layers in said systems contains a silicone hot-melt adhesive, a pharmaceutical product, and particles made of crosslinked polyvinylpyrrolidone. The invention also relates to a method for producing said transdermal therapeutic systems.

Abstract: The present invention relates to a method for stabilizing rotigotine, the method comprising providing a solid dispersion comprising polyvinylpyrrolidone and a nom-crystalline form of rotigotine, wherein the weight ratio of rotigotine to polyvinylpyrrolidone is in a range from about 9:3.5 to about 9:6. The present invention also relates to a solid dispersion comprising a dispersing agent and a dispersed phase, said dispersed phase comprising rotigotine and polyvinylpyrrolidone wherein the weight ratio of rotigotine to polyvinylpyrrolidone is in a range from about 9:3.5 to about 9:6, a pharmaceutical composition comprising such a solid dispersion, in particular a transdermal therapeutic system, as well as a method for the preparation thereof.

Abstract: A device for measuring a slaughter animal body object includes an image camera having an image-camera recording region, a depth camera having a depth-camera recording region, and an evaluation unit. The cameras are positioned in relation to one another by a positioning device in such a manner that the camera recording regions of the image camera and of the depth camera overlap in a common camera recording region at least in certain sections. The evaluation unit identifies measurement points in the common camera recording region and determines the distances thereof from one another.

Abstract: Disclosed is a patient interface for affixment on onto a patient eye, said patient interface including: a negative-pressure cavity designed for fluidic coupling to the patient eye; a first negative pressure interface with a first negative pressure aperture for fluidically coupling the negative-pressure cavity to a negative-pressure device to charge the negative pressure cavity with a negative pressure; a second negative pressure interface with a second negative pressure aperture for fluidically coupling the negative-pressure cavity to the negative-pressure device to charge the negative cavity with a negative pressure; wherein the first negative pressure aperture and the second negative pressure aperture are arranged in a wall of the negative pressure cavity separate from and in close vicinity to each other.

Abstract: PV layer sequences and corresponding production methods which can reliably provide a PV function with a long service life despite very low production costs. This is achieved by a reactive conditioning process of inorganic particles as part of a room-temperature printing method; the reactive surface conditioning process adjusts the PV activity in a precise manner, provides a kinetically controlled reaction product, and can ensure the desired PV activity even when using technically pure starting materials with 97% purity. In concrete embodiments, particles are printed in composite so as to form sub-sections on a support. Each sub-section has a reductively treated section and an oxidatively treated section, and the sections have PV activity with opposite signs. The sections can be cascaded in rows via upper-face contacts, and a precise light-dependent potential sum can be tapped via a PV measuring group.

Abstract: The invention relates to a filter arrangement having a first busbar, a second busbar and a carrier element, on which at least one electrical filter component is arranged, which is electrically connected to the busbars, wherein the electrical connection of the at least one electrical filter component to at least one of these busbars is realized by mechanical clamping of the carrier element between the first and second busbar.

Abstract: An edible oral film strip dosage form containing an unpalatable basic active pharmaceutical ingredient and an ion exchange resin as a primary taste masking agent, along with an optional acidic agent and further optionally containing one or more secondary taste masking agents is provided. The edible oral film strip dosage matrix is formed from at least one water soluble or miscible polymer(s). The optional secondary taste masking ingredients include one or more of flavoring agent(s), sweetener(s), cooling sensation agent(s), and taste receptor blocker(s). Methods for preparing the inventive edible oral film strip dosage forms are disclosed, as well as their method of administration.

Abstract: An apparatus for assessing compliance with animal welfare on an animal for slaughter. The apparatus has an image capture unit with a capture region in which a section of a surface of the animal is optically captured and in which pixels are captured. The capture unit provides pixel data in a transmittable manner. The apparatus has an evaluation unit connected to the capture unit to capture the pixel data. A normative model of the animal is stored in the evaluation unit and represents a formation of animal-related features conforming to animal welfare. The evaluation unit relates the pixel data to the model and determines a deviation of the pixel data from the model and provides the deviation as a deviation of the animal from the model in a form that can be output. A method for assessing compliance with animal welfare is carried out on the apparatus.

Abstract: The invention relates to transdermal therapeutic systems (TTS) which include, as active ingredient, the NMDA receptor antagonist memantine or one of its physiologically compatible salts. The TTSs can be produced and used for treating diseases of the central nervous system.

Abstract: The present invention relates to a method for stabilizing rotigotine, the method comprising providing a solid dispersion comprising polyvinylpyrrolidone and a non-crystalline form of rotigotine, wherein the weight ratio of rotigotine to polyvinylpyrrolidone is in a range from about 9:3.5 to about 9:6. The present invention also relates to a solid dispersion comprising a dispersing agent and a dispersed phase, said dispersed phase comprising rotigotine and polyvinylpyrrolidone, wherein the weight ratio of rotigotine to polyvinylpyrrolidone is in a range from about 9:3.5 to about 9:6, a pharmaceutical composition comprising such a solid dispersion, in particular a transdermal therapeutic system, as well as a method for the preparation thereof.

Abstract: The invention relates to a medical product for a fastening duration of at least 7 days having good skin compatibility. The medical product includes a central adhesive compartment (3) and an over-patch. The over-patch is free of active ingredients and is formed from a water-vapor-permeable back layer (1) and an adhesive polymer layer (2) that is free of active ingredients. The invention further relates to a method for the production of the foregoing medical product, and to kits of parts containing laminates of layers 1 and 2.

Abstract: The invention relates to a transdermal therapeutic system, preferably a transdermal patch, having an active ingredient-containing matrix formed substantially of a water-insoluble base material, such as rubber and synthetic polymers, into which is incorporated water-soluble and/or water-swellable inclusion bodies, e.g. inclusion bodies formed from polyvinyl alcohol or polyethylene glycol, that further include micronized or nanoscale active ingredient particles.

Abstract: A method to capture data for animals to be slaughtered with an image capture unit that has an image capture range in which a surface of an animal to be slaughtered is captured visually and in which image points on the surface of the animal are captured. The capture unit provides image point data from the image points in transmittable form. An evaluation unit captures the point data and uses the point data to capture markings on the rear surface of the animal. The evaluation unit provides the markings as a storable capture result. Image points on the surface of the animal are captured in the image capture range. The points contain the markings. The capture unit transmits the point data. The evaluation unit captures the image point data. The method makes an association of an identification code for an animal with the point data. The evaluation unit provides the markings as a storable capture result with the code for the animal.

Abstract: Interferometer (10) for the real-time measurement of absolute distances and/or relative position movements between a first and a second machine part, comprising a measurement unit (20) and a reflector unit (40). wherein the measurement unit (20) comprises a housing (21) with at least one wall made of heat-conducting material, wherein several measurement elements are arranged in the housing (21), wherein the measurement elements comprise: a laser source (22), a Peltier element (24) and a digital control (23) wherein the measurement elements are thermally coupled to the wall of the housing (21) made of heat-conducting material.

Abstract: An implantable device comprising a driving unit and a kinematic assembly joined together: the driving includes, in an hermetic capsule, electromechanical component, like an electric motor and, the battery pack, and electronic elements, while the kinematic assembly includes a reducer and an actuator, for example a lead-screw distractor, and is lubricated by body fluids. Mechanical energy is transmitted without contact from the former to the latter by a magnetic transmission.

Abstract: Proposed is a monitoring apparatus for a sanitary installation, comprising a first sensor for monitoring the presence of persons in a first spatial region in the surroundings of the sanitary installation and comprising a second sensor for monitoring a second spatial region in the surroundings of the sanitary installation, wherein the first sensor comprises an operating mode and a standby mode and the second sensor is embodied to switch the first sensor from a standby mode into an operating mode in the case of a predetermined detection. In order to avoid faults in the operating procedure, the first sensor is embodied as a distance sensor, in particular as a TOF sensor.

Abstract: An ophthalmological device (10) for treating eye tissue (6) with laser pulses (L) comprises a projection optical unit (3) for focused projection of the laser pulses (L), a scanner system (1) for dynamically deflecting the laser pulses (L) and a zoom system (20), which is arranged between the projection optical unit (3) and the scanner system (1) and which is configured to adjust the focused projection of the laser pulses (L) in the projection direction (r) in different zoom settings (z). The ophthalmological device (10) moreover comprises a displacement device (4), which is configured to displace the scanner system (1) depending on the zoom setting (z) of the zoom system (20).

Abstract: The invention relates to a negative-pressure device (1) for affixing a patient interface (2) with a negative-pressure cavity (20) onto a patient eye. The negative-pressure device (1) comprises a negative-pressure generator (10) and a pressure sensor (11) with a device-side pressure sensor interface (14) for coupling the pressure sensor (11) to the negative-pressure cavity in a manner fluidically separate from the negative-pressure interface (13). The negative-pressure device furthermore relates to a control unit (12) operatively coupled to the negative-pressure generator (10) and the pressure sensor (11), wherein the control unit (12) is designed to detect a faulty fluidic coupling of the negative-pressure cavity (20) by evaluating a pressure established by the pressure sensor (11).