Abstract: The invention relates to a negative-pressure device (1) for affixing a patient interface (2) with a negative-pressure cavity (20) onto a patient eye. The negative-pressure device (1) comprises a negative-pressure generator (10) and a pressure sensor (11) with a device-side pressure sensor interface (14) for coupling the pressure sensor (11) to the negative-pressure cavity in a manner fluidically separate from the negative-pressure interface (13). The negative-pressure device furthermore relates to a control unit (12) operatively coupled to the negative-pressure generator (10) and the pressure sensor (11), wherein the control unit (12) is designed to detect a faulty fluidic coupling of the negative-pressure cavity (20) by evaluating a pressure established by the pressure sensor (11).
Abstract: Heat engine and method for operating a heat engine are disclosed. A disclosed method for operating a heat engine-includes supplying gas containing combustible constituents as supply air to a combustion chamber of a combustion apparatus-of the heat engine; supplying fuel to the combustion chamber; removing exhaust gas from the combustion chamber and supplying the exhaust gas to a heat exchanger of the heat engine; transferring heat from the exhaust gas to at least a part of the supply air by the heat exchanger; guiding a part of at least one of the supply air or a part of the exhaust gas past the heat exchanger by a bypass guide, wherein at least one of a mass stream or volumetric stream of at least one of the part of the supply air or the exhaust gas guided past the heat exchanger-is at least one of controlled or regulated-so that at least one of a thermal power or a mechanical power of the heat engine is approximately constant over time.
Abstract: A container assembly includes at least one container that can be stacked, which has a base unit having a main accommodating body and having a carrying handle and which also has two auxiliary accommodating bodies, which sit on the main accommodating body and cover a main accommodating chamber formed therein in a basic position. Each auxiliary accommodating body has an auxiliary accommodating chamber that can be closed by means of a pivotable closing cover. The auxiliary accommodating bodies can be moved into an access position, in which the auxiliary accommodating bodies make the main accommodating chamber accessible. In addition, couplers are arranged on the base unit wherein the couplers enable vertical coupling of a plurality of stacked containers.
Abstract: A thermal insulation panel is provided for thermally insulating edifices. The thermal insulation panel contains at least one aerogel and is open to diffusion along the panel's main insulating direction.
Abstract: The invention relates to a device for optically identifying the sex of a slaughter pig with a depth camera that has a depth camera acquisition region in which a genital region of the pig and spatial coordinates of pixels are acquired. The spatial coordinates are provided in a transmittable manner and include a positioning device to position the depth camera relative to the genital region of the pig. The device includes an evaluation unit connected to the depth camera. The spatial coordinates are acquired by the evaluation unit to determine a phenotypic sex of the pig.
Abstract: The present invention relates to a method for stabilizing rotigotine, the method comprising providing a solid dispersion comprising polyvinylpyrrolidone and a non-crystalline form of rotigotine, wherein the weight ratio of rotigotine to polyvinylpyrrolidone is in a range from about 9:3.5 to about 9:6. The present invention also relates to a solid dispersion comprising a dispersing agent and a dispersed phase, said dispersed phase comprising rotigotine and polyvinylpyrrolidone, wherein the weight ratio of rotigotine to polyvinylpyrrolidone is in a range from about 9:3.5 to about 9:6, a pharmaceutical composition comprising such a solid dispersion, in particular a transdermal therapeutic system, as well as a method for the preparation thereof.
Type:
Grant
Filed:
January 31, 2018
Date of Patent:
November 20, 2018
Assignees:
UCB Pharma GmbH, LTS Lohmann Therapie-Systeme AG
Inventors:
Hans-Michael Wolff, Christoph Arth, Luc Quere, Walter Müller
Abstract: An electromechanical actuator includes an oscillation resonator having the shape of a rod. The oscillation resonator is divided by a dividing plane that is not parallel to the longitudinal direction of the oscillation resonator into a first resonator portion and a second resonator portion. At least the first resonator portion includes electromechanical means which, when activated, are configured to generate a 3-dimensional acoustic bulk wave are with a mode shape asymmetric with respect to the dividing plane.
Abstract: Disclosed is a method for marking film-type dosage forms, comprising at least the positioning of a film-type dosage form between two layers of a scalable packaging material, the sectional heat-scaling of the two layers of the scalable packaging material so as to obtain an edge-sealed bag containing the film-type dosage form, and the blind-embossing of the film-type dosage form contained in the edge-sealed bag through at least one of the two layers of packaging material of the edge-sealed bag.
Type:
Application
Filed:
October 28, 2016
Publication date:
November 1, 2018
Applicant:
LTS Lohmann Therapie-Systeme AG
Inventors:
Petra Botzem, Torsten Grunenberg, Thomas Hille, Peter Steinborn
Abstract: The invention relates to a timing system for measuring a runner's (2) running time between two presence points (3) of the runner's running path, comprising a measurement beam receiver (MSE (5)) and a measurement beam emitter (MSG (6)). The measurement beam (8) from these intersects said running path. When reception of the measurement beam is interrupted, presence signals are generated for the runner that are evaluated in the timer (8) in order to acquire and output the running time. In a running path with a turn-around between a start/finish line (SZL (10)) and a turn-around point (4.3), or a running path that is undulating to zig-zagged, the measurement beam receiver MSG (beam source 6.2, mirror 6.1) is situated at the ends of said running path. Presence signals are generated at the turn-around point (4.3) and/or at least one of the turning points (3) of said running path. In addition, the pairing of an additional measurement beam receiver [start/finish MSE (5.2)] and beam source (6.
Abstract: Transdermal therapeutic systems are described which have at least one electronic component, as well as methods for producing this type of transdermal therapeutic systems.
Type:
Application
Filed:
June 15, 2018
Publication date:
October 11, 2018
Applicant:
LTS Lohmann Therapie-Systeme AG
Inventors:
Wolfgang Laux, Beatrix Platt, Nico Reum
Abstract: The present invention relates to a method for stabilizing rotigotine, the method comprising providing a solid dispersion comprising polyvinylpyrrolidone and a non-crystalline form of rotigotine, wherein the weight ratio of rotigotine to polyvinylpyrrolidone is in a range from about 9:3.5 to about 9:6. The present invention also relates to a solid dispersion comprising a dispersing agent and a dispersed phase, said dispersed phase comprising rotigotine and polyvinylpyrrolidone, wherein the weight ratio of rotigotine to polyvinylpyrrolidone is in a range from about 9:3.5 to about 9:6, a pharmaceutical composition comprising such a solid dispersion, in particular a transdermal therapeutic system, as well as a method for the preparation thereof.
Type:
Application
Filed:
May 17, 2018
Publication date:
September 20, 2018
Applicants:
UCB Pharma GmbH, LTS Lohmann Therapie-Systeme AG
Inventors:
Hans-Michael WOLFF, Christoph ARTH, Luc QUERE, Walter MÜLLER
Abstract: Transdermal therapeutic systems are described which have at least one electronic component, as well as methods for producing this type of transdermal therapeutic systems.
Type:
Grant
Filed:
July 3, 2014
Date of Patent:
August 14, 2018
Assignee:
LTS Lohmann Therapie-Systeme, AG
Inventors:
Wolfgang Laux, Beatrix Platt, Nico Reum
Abstract: Transdermal therapeutic system for the transdermal administration of a systemically active agent comprising a self-adhesive layer structure, comprising A) a backing layer, and B) a dried biphasic layer, the dried biphasic layer having a) an outer phase having a composition comprising 75% to 100% of a polymer or polymer mixture, and b) an inner phase having a composition comprising at least one active agent, wherein the inner phase forms dispersed deposits in the outer phase, and c) 0.1% to 3.5% of an interface mediator with a kinematic viscosity of from 10 cSt to 100 000 cSt at 25° C., and and C) optionally an additional skin contact layer.
Abstract: Monolayered or multilayered, film-shaped, pressure-sensitive adhesive preparations for application in the oral region and a process for manufacturing such preparations. The preparations contain at least one polymethyl vinyl ether-maleic acid anhydride copolymer, polyvinyl acetate and/or at least one copolymer of the polyvinyl acetate with vinyl alcohol esters of fatty acids, as well as at least one cosmetic and/or pharmaceutical active substance.
Abstract: The invention generally relates to a transdermal therapeutic system which comprises a backing layer, an adhesive layer, a polymer layer and a removable protective layer. The adhesive layer is an organosiloxane layer that is anchored to the backing layer by siliconization.