Abstract: An ophthalmological patient interface apparatus, having a coupling apparatus for mechanically coupling to an application head of an ophthalmological laser system, comprises a lens-element system which is arranged between the eye and the application head in the state coupled to the application head during the treatment of an eye, said lens-element system being coupled into the beam path from the projection lens to the eye. The lens-element system is configured to image a first focal area of the projection lens disposed upstream of the lens-element system in the beam path onto a second focal area in the eye disposed downstream of the lens-element system in the beam path, in such a way that a laser beam focused onto the first focal area by the projection lens causes tissue processing in the second focal area in the eye.

Abstract: The disclosure relates to a supply system for supplying multiple consumers with a substance to be applied, preferably paint, for application to motor vehicle bodies and/or add-on parts thereof. The supply system comprises a feed line, a return line, a first consumer device which comprises a first consumer, the first consumer being connected to the feed line and the return line and preferably forming a first consumer of the feed line in the flow direction of the substance to be applied, and a further consumer device which comprises a further consumer, the further consumer being connected to the feed line and the return line and preferably forming a last consumer of the feed line in the flow direction of the substance to be applied and/or being arranged after the first consumer in the flow direction of the substance to be applied. The supply system is distinguished in particular in that the feed line is connected to the return line via a connecting line.

Abstract: The present invention relates to a transdermal therapeutic system, comprising (a) a backing layer, (b) a solvent-based self-adhesive matrix layer containing rotigotine as active ingredient, and (c) a release liner, wherein the self-adhesive matrix layer has a coating weight of about 75-400 g/m2 and comprises a reservoir layer containing about 9-25 wt.-% rotigotine based on the weight of the reservoir layer, a kit comprising two transdermal therapeutic systems of the present invention as well as a method for the preparation of the transdermal therapeutic system of the present invention.

Abstract: An electrically-heatable plaster that comprises a self-adhesive skin contact layer, an electrically-conductive textile fabric in which electrically-conductive fibres are in contact with one another, as a heating element, and optionally at least one active substance, as well as to a method for production and the use of same for local heat therapy and/or transdermal application of active substances.

Abstract: The present application refers to a method and a system for reliably forwarding data packets in a source-selected path routing network including a plurality of autonomous systems. For this purpose, a data plane of each of the plurality of autonomous systems that comprises one or more border routers and a control plane of each of the plurality of autonomous systems that comprises a control service are split into two or more shards. Each of said shards contains exactly one control service and at least one border router and is responsible for processing, storing and propagating path information only for a subset of existing links between an autonomous system and a neighboring autonomous system within the source-selected path routing network. Hence, in the source-selected path routing network, each individual shard is not critical and thus can fail without compromising the availability of the entire system.

Abstract: The present application generally relates to a system and method for interfacing a source-selected path routing network with existing legacy IP networks. This interfacing may be achieved by installing specific router devices at the borders of the source-selected path routing network. Said router devices are able to exchange routing information in the form of IP prefix announcements and withdrawals between legacy IP networks and the source-selected path routing network according to an appropriate exterior gateway protocol. Hereby, the source-selected path routing network that in reality comprises a plurality of autonomous systems is conceptually regarded as a single autonomous system. Hence, a legacy IP network that is a direct neighbor of a source-selected path routing network may ensure that traffic destined to it traverses the source-selected path routing network by announcing its routing information only to the source-selected path routing network via an appropriate exterior gateway protocol.

Abstract: The present invention relates to a microneedle system (MNS) for intradermally delivering solutions or formulations. The invention relates to a microneedle system, comprising a cover element (1), an active substance container (2), a frame (3), a microneedle array (MNA) (4) and a base plate (5), wherein the microneedle array (MNA) (4) is connected to the frame (3), and the base plate (5) has an opening for receiving the microneedle array (4), the cover element (1) and the base plate (5) are movably connected to one another, the base plate (5) is joined to a surgical tape (6), and the frame (3) and the base plate (5) can be linearly displaced with respect to one another. The MNS according to the invention is suitable for intradermally administering medicinal drugs, active substances, pharmaceutical or cosmetic compositions or other substances to an individual, and preferably to a patient, over an extended period.

Abstract: The present invention relates to a transdermal therapeutic system (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure comprising a therapeutically effective amount of asenapine, said self-adhesive layer structure comprising: A) a backing layer; B) an asenapine-containing layer comprising: 1. asenapine in the form of the free base; and 2. a polymer selected from the group consisting of polysiloxanes and polyisobutylenes in an amount of more than 50% by weight based on the total weight of the asenapine-containing layer; and C) optionally an additional skin contact layer.

Abstract: The disclosure concerns a printhead for the application of a coating agent to a component, in particular for painting a vehicle body component with a paint. The disclosure provides that the printhead is designed in such a way that it enables a color change during coating operation and can be rinsed with a rinsing agent during a color change in order to rinse out coating agent residues from the printhead.

Abstract: The present invention relates to a transdermal therapeutic system formed from (a) a backing layer, (b) a solvent-based self-adhesive matrix layer containing rotigotine as active ingredient, and (c) a release liner, in which the self-adhesive matrix layer has a coating weight of about 75-400 g/m2 and comprises a reservoir layer containing about 9-25 wt.-% rotigotine based on the weight of the reservoir layer; a kit containing two transdermal therapeutic systems of the present invention; and methods for the preparation of the transdermal therapeutic system of the present invention. The present invention further relates to methods of treatment based upon the application of the inventive transdermal therapeutic systems once or twice weekly via systems adapted to allow for the transdermal administration of therapeutically effective amounts of rotigotine for at least 3 days.

Abstract: An ophthalmological device for treating eye tissue with laser pulses comprises a projection optical unit for focused projection of the laser pulses, a scanner system for dynamically deflecting the laser pulses and a zoom system, which is arranged between the projection optical unit and the scanner system and which is configured to adjust the focused projection of the laser pulses in the projection direction in different zoom settings. The ophthalmological device moreover comprises a displacement device, which is configured to displace the scanner system depending on the zoom setting of the zoom system. What the displacement of the scanner system coupled to the zoom setting of the zoom system renders possible is the adaptation of the position of the scanner system in a dynamic and synchronized fashion to the setting of the zoom system and hence to the current position of the virtual entry pupil of the zoom system.

Abstract: In order to create a conveying system which is of simple construction and enables an efficient conveyance of objects, it is proposed that the conveying system comprises a first conveying device and a second conveying device, wherein the objects are able to be taken over from the first conveying device and/or are transferrable to the first conveying device by means of the second conveying device.

Abstract: A transdermal therapeutic system which is free of fibrous constituents, and a method for the production of such a transdermal therapeutic system A preparation containing active substance is applied by a printing method onto the pressure-sensitive adhesive layer of the transdermal therapeutic system.

Abstract: The invention relates to a transdermal therapeutic system that includes a) a backing layer which faces away from the skin, is impermeable to the active substance, and is equipped with an adhesive layer for fixing onto the skin, b) an active substance reservoir which contains at least one active substance, c) a barrier layer which faces the skin, adjoins the active substance reservoir, is impermeable to the active substance and has at least one opening, and d) a removable protective layer, in which the backing layer which is equipped with the adhesive layer projects beyond the barrier layer on all sides.

Abstract: The disclosure relates to an application device for applying an application medium onto a component, preferably for application of a coating onto a motor vehicle body component. The application device includes a print head for preferably serial and/or permanent application of the application medium, wherein the print head has: a nozzle plate, at least one nozzle in the nozzle plate in order to discharge the application medium, at least one valve element, which is movable relative to the nozzle plate, for control of the application medium discharge through the at least one nozzle, wherein the at least one movable valve element closes the at least one nozzle in a closing position and releases it in an opening position, and at least one drive for moving the at least one valve element. The application device is characterised in particular in that it includes at least one temperature control apparatus for reducing heating of the at least one drive during application of the application medium.

Abstract: Adhesive bandages are provided with a water-vapor permeable back layer and an adhesive layer, in which the adhesive layer includes 10 weight percent of a disperse internal phase of hydrophilic particles that are water-swellable in an outer phase that includes at least 10 weight percent of a styrene block copolymer and at least 20 weight percent of an ester resin of colophony, and that can further contain at least one anti-virus substance.

Abstract: The invention relates to a system containing: a transdermal therapeutic system (TTS); a cylindrical separating layer having an outer periphery and an inner periphery; and a backing layer, which is applied to the cylindrical separating layer and protrudes beyond the cylindrical separating layer over the entire periphery. The invention further relates to a system for improving the adhesion of a TTS, to the use of the system, and to a kit containing the system.

Abstract: A coating apparatus for coating a component with a coating agent includes an applicator for delivering at least one coating agent jet of the coating agent to the component. The coating apparatus includes an intercepting device which in an active position intercepts the at least one coating agent jet between the applicator and the component so that the at least one coating agent jet does not strike the component.

Abstract: The disclosure relates to an application device for applying an application medium onto a component, preferably for application of a coating onto a motor vehicle body component. The application device includes a print head for preferably serial and/or permanent application of the application medium, wherein the print head has: a nozzle plate, at least one nozzle in the nozzle plate in order to discharge the application medium, at least one valve element, which is movable relative to the nozzle plate, for control of the application medium discharge through the at least one nozzle, wherein the at least one movable valve element closes the at least one nozzle in a closing position and releases it in an opening position, and at least one drive for moving the at least one valve element. The application device is characterised in particular in that it includes at least one temperature control apparatus for reducing heating of the at least one drive during application of the application medium.

Abstract: The invention is directed to a computer-implemented system and method for transmitting data from a first node to a second node of a source-selected path routing network. In said system and method according to the present invention, a first data packet is received at the first node, wherein said data packet was sent from a source node according to next-hop routing. Subsequently, at least part of the data contained in the data packet is transmitted from the first node to the second node according to source-selected path routing. Finally, the data received at the second node is transmitted to a destination node according to next-hop routing.