Abstract: Various embodiments of the present technology generally relate to Global Navigation Satellite Systems (GNSS). More specifically, the embodiments of the present technology relate to a smart antenna module resistant to Radio Frequency Interference (RFI) saturation for dual-frequency GNSS receivers. In some embodiments, a dynamically configured antenna module architecture can be for a dual-band (or multi-frequency) GNSS receiver that can adapt to different RFI conditions by performing corresponding working modes. For example, some embodiments of the smart antenna can measure (e.g., using a power detector) the power of an incoming multi-frequency signal to determine when the multifrequency signal is saturated. Then, using control logic the smart antenna can determine which frequency in the multi-frequency signal is usable and isolate (e.g. using radio frequency components) a frequency that is not saturated. A position estimate can then be generated based on the isolated multi-frequency signal.

Abstract: The present invention includes compounds, compositions and methods for treating and/or preventing chlorine inhalation toxicity and/or injury in a subject subjected to chlorine inhalation.

Abstract: Various embodiments of the present technology generally relate to identification of tumor location. More specifically, some embodiments of the present technology relate automated tracking of fiducial marker clusters in x-ray images for the real-time identification of tumor location and guidance of radiation therapy beams. Some embodiments use processed CBCT projection images, an automated routine of reconstruction, forward-projection, tracking, and stabilization generated static templates of the marker cluster at arbitrary viewing angles. Breathing data can be incorporated into some embodiments, resulting in dynamic templates dependent on both viewing angle and breathing motion. In some embodiments, marker clusters can be tracked using normalized cross correlations between templates (either static or dynamic) and CBCT projection images.

Abstract: Described herein are devices in which quantum noise is reduced, such as by incorporating the devices as part of or adjacent to a Casimir cavity. The devices with reduced quantum noise can be paired with a free-space electric device to allow for a difference in noise power between the two to be captured.

Abstract: Described herein are systems incorporating a Casimir cavity, such as an optical Casimir cavity or a plasmon Casimir cavity. The Casimir cavity modifies the zero-point energy density therein as compared to outside of the Casimir cavity. The Casimir cavities are paired in the disclosed systems with product generating devices and the difference in zero-point energy densities is used to directly drive the generation of products, such as chemical reaction products or emitted light.

Abstract: The present invention provides an apparatus for the measurement and monitoring of the breathing volume of a subject. In certain embodiments, the invention further provides a method of using the apparatus to diagnose a subject as suffering from a respiratory disorder. In other embodiments, the apparatus and method can be used to monitor the breathing volume of a subject, while compensating for random body movement of the subject during the monitoring period.

Abstract: The present invention relates generally to X-ray detectors and more particularly to a system and a method for integrating an anti-scattering grid with scintillators to significantly enhance the performance of flat panel X-ray detector. In particular, the performance of a flat panel X-ray detector may be enhanced by photon counting detector pixels configured underneath the septa of a 2D antiscatter grid.

Abstract: Embodiments of the disclosure provide for hierarchically distributed voltage regulation and power flow optimization in a power distribution network. According to one embodiment, a regional coordinator system may determine power flow for an autonomous grid (AG) representing a portion of the distribution network based on a set of voltage parameters from nodes in the AG. The set of voltage parameters my include a current voltage magnitude. The regional coordinator system may provide, to a central controller system of the distribution network, one or more power flow parameters based on the determined power flow for the AG.

Abstract: Wide-angle beam steering using two or more variable lenses to form a small-angle beam steering element, along with a numerical aperture converter and a wide-angle lens. The small-angle beam steering element might comprise either one- or two-dimensional beam steering with tunable liquid lenses.

Abstract: The present invention provides a method for determining a treatment procedure for breast cancer, a method of predicting a likelihood of success in treating breast cancer, and a method for selecting an endocrine therapy agent for treating breast cancer. In particular, methods of the present invention rely on the amount of androgen receptor (AR) and estrogen receptor (ER) in a tissue sample.

Abstract: An implantable device comprising a substrate capable of capturing an intraocular target molecule and to methods of use thereof. The substrate may be capable of capturing a target molecule present in the eye and/or from fluid of the eye (e.g., an intraocular target molecule). In some embodiments, the substrate has a relatively high affinity for a target molecule.

Abstract: Described herein are devices incorporating Casimir cavities, which modify the quantum vacuum mode distribution within the cavities. The Casimir cavities can drive charge carriers from or to an electronic device disposed adjacent to or contiguous with the Casimir cavity by modifying the quantum vacuum mode distribution incident on one side of the electronic device to be different from the quantum vacuum mode distribution incident on the other side of the electronic device. The electronic device can exhibit a structure that permits transport or capture of hot carriers in very short time intervals, such as in 1 picosecond or less.

Abstract: A respiration rate measurement apparatus including a plurality of sensors for concurrently generating temperature, pressure and acoustic data representing one or more successive breaths and a method of generating fusion data from the plurality of data streams as a weighted average based on determined correlation coefficients and calculation of a respiratory rate.

Abstract: A lacrimal drug delivery device includes a reservoir configured to hold a drug. The reservoir is moveable between a relaxed state and an expanded state. A connector is fluidly coupled to the reservoir and a lumen is formed in the connector wherein the drug is configured to flow from the reservoir to an delivery site through the lumen. A hydrogel is within the lumen and configured to absorb the drug from the reservoir and deliver the drug from the lumen at the delivery site. The hydrogel includes a first section which absorbs the drug at a first rate of absorption. A delivery guide is detachably coupled to the reservoir to deliver the reservoir into a lacrimal sac of a patient.

Abstract: An ophthalmic implant configured for peri-operative, intra-operative, or post-operative assembly and disassembly. Drug delivery devices may be implanted with an intraocular lens, and later removed and replaced with new drug delivery devices.

Abstract: Embodiments of the present invention provide compositions and methods for recombinantly generating tagless constructs of proteins or peptides. In certain embodiments, recombinant proteins or peptides disclosed herein concern human papilloma virus (HPV). Other embodiments concern using these constructs in compositions to elicit immune responses in a subject to one or more HPV types. Therapeutic and prophylactic vaccines for the prevention and treatment of viral infections are also disclosed. Nucleic acids and expression vectors coding for constructs contemplated herein are provided. In certain embodiments, an HPV capsid protein generated is devoid of any fusion tags. In addition, truncated forms of HPV L1 are contemplated.

Abstract: In some embodiments, the invention provides an in vitro method for identifying a patient as likely as likely to require a transfusion of at least six units of blood in six hours or less. The method comprise, consists essentially of, or consists of (a) analyzing a sample of blood from a patient with a viscoelastic analysis assay to obtain a coagulation characteristic value that is independent of time of the patient; and (b) comparing the coagulation characteristic value of the patient to a coagulation characteristic value that is independent of time of a control, wherein the coagulation characteristic value of the patient that is lower than the coagulation characteristic value of the control identifies the patient as likely to require a transfusion of at least six units of blood in six hours or less.

Abstract: The invention provides devices that can be used for any endoscopy procedure. In certain embodiments, the devices of the invention reduce the occurrence of looping in the most difficult segment of the colon to navigate—the splenic flexure. In other embodiments, the devices of the invention make colonoscopies more comfortable for patients and reduce the risk of damage to the colon. In yet other embodiments, the devices of the invention comprise a supportive, friction-reducing device that can be attached to the tip of existing endoscopes to help the scope advance better through the colon and intestinal tract.

Abstract: A Disease Severity Index (DSI) is provided for assessment of chronic liver disease in a patient using non-invasive liver function test results. A DSI was derived from non-invasive liver function test results based on hepatic blood flow. The DSI is used in methods for prediction of clinical outcomes, prediction of response to antiviral treatment, and assessment of progression of chronic liver diseases. Non-invasive methods to diagnose three distinct categories of patients with Primary Sclerosing Cholangitis (PSC) are provided. The methods can be used to diagnose PSC patients as Slow Progressors, Moderate Progressors and Rapid Progressors.

Abstract: Disclosed are cellulose-based flexible gels containing cellulose nanorods, ribbons, fibers, and the like, and cellulose-enabled inorganic or polymeric composites, wherein the gels have tunable optical, heat transfer, and stiffness properties. The disclosed gels are in the form of hydrogels, organogels, liquid-crystal (LC) gels, and aerogels, depending on the solvents in the gels.