Patents Assigned to The University
  • Patent number: 9345776
    Abstract: The present invention provides methods for preparing polysulfenamides having a repeating unit of formula (4): wherein R1 is selected from the group consisting of alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, ether, cycloether, aryl, heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl. Each of R4, R5 and R6 are independently selected from the group consisting of alkyl, alkenyl, alkynyl, haloalkyl, alkoxyalkyl, hydroxyalkyl, ether, cycloether, aryl, heteroaryl, arylalkyl, heteroarylalkyl, hydroxyaryl, arylether, cycloalkyl, heterocycloalkyl, hydroxycycloalkyl, halocycloalkyl, and aminocycloalkyl. Microparticles comprising polysulfenamides can be used as delivery vehicles for a variety of biological applications.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: May 24, 2016
    Assignee: The University of Iowa Research Foundation
    Inventors: Ned B. Bowden, Denison J. Kuruvilla, Aliasger K. Salem, Jun Yoo
  • Patent number: 9347929
    Abstract: Improved resolution and detection of nanoparticles are achieved when a nanopore connecting liquid compartments in a device running on the Coulter principle is provided with fluid lipid walls. The fluid lipid walls are made of a lipid bilayer, and preferably include lipid anchored mobile ligands as part of the lipid bilayer. By varying the nature and concentration of the mobile ligand in the lipid bilayer, multifunctional coatings of lipids are provided.
    Type: Grant
    Filed: February 20, 2012
    Date of Patent: May 24, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Michael Mayer, Erik Yusko, Jerry Yang
  • Patent number: 9345790
    Abstract: Novel, non-toxic cobalt-based contrast and imaging agents for use in enhanced medical imaging modalities and processes are described, as well the manufacture of markers containing such contrast agents is described, and uses for such imaging markers and contrast agents in a variety of therapeutic applications and devices.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: May 24, 2016
    Assignees: Board of Regents, The University of Texas System, The University of Houston System
    Inventors: Steven J. Frank, Karen Martirosyan
  • Patent number: 9346686
    Abstract: A one-pot approach for preparing ArSH capped Cu2ZnSnS4, Cu2ZnSn(S(1-x)Sex)4, Cu2SnS3, CuInS2, and CuIn(S(1-x)Sex)2 nanocrystals is provided. Examples involving reacting copper (II) acetylacetonate and indium chloride with thiourea and 2-mercapto-5-n-propylpyrimidine in the presence of an organic solvent are described. Monodispersed CuInS2, nanocrystals having a size of about 100 nm were prepared. Examples involving reacting copper (II) acetylacetonate, zinc chloride, and tin chloride with thiourea and 2-mercapto-5-n-propylpyrimidine in the presence of an organic solvent are described. Monodispersed Cu2ZnSnS4 nanocrystals having a size of about 2 nm were prepared. Nanociystals obtained were found to have excellent crystallinity, stoichiometry, and high collective photovoltaic activity without the need for postprocessing such as high temperature annihilation in a sulfur atmosphere.
    Type: Grant
    Filed: December 24, 2012
    Date of Patent: May 24, 2016
    Assignee: The University of Western Ontario
    Inventors: Zhifeng Ding, Falong Jia, Dave Love, Myong In Oh, Daniel Vaccarello, Amy Tapley
  • Publication number: 20160137778
    Abstract: Described are shape memory polymers and methods of making shape memory polymers and actuators from the shape memory polymers.
    Type: Application
    Filed: October 29, 2015
    Publication date: May 19, 2016
    Applicant: The University of Rochester
    Inventors: Mitchell Anthamatten, Yuan Meng
  • Publication number: 20160138133
    Abstract: Methods for extraction and recovery of rare earth elements are disclosed. In one aspect, heap leaching with a leach solution comprising sulfuric acid is used to extract rare earth elements including yttrium and light and heavy rare earth elements.
    Type: Application
    Filed: November 13, 2015
    Publication date: May 19, 2016
    Applicant: Board of Regents, The University of Texas System
    Inventor: Nicholas E. Pingitore, JR.
  • Publication number: 20160136151
    Abstract: The invention provides a method of treating anxiety or a compulsive disorder in a subject comprising administering to the subject a compound having formula 2: or a pharmaceutically acceptable salt or solvate thereof, wherein R, R1, R2, R3, R4, R5, and X are as defined in the specification.
    Type: Application
    Filed: January 20, 2016
    Publication date: May 19, 2016
    Applicant: The University of Bath
    Inventors: John Lewis, Stephen Husbands
  • Publication number: 20160137749
    Abstract: Embodiments concern methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. Aspects include methods and compositions for providing a passive immune response against the bacteria. In certain embodiments, the methods and compositions involve an antibody that binds Staphylococcal protein A (SpA).
    Type: Application
    Filed: March 12, 2014
    Publication date: May 19, 2016
    Applicant: The University of Chicago
    Inventors: Olaf SCHNEEWIND, Dominique M. MISSIAKAS, Hwan Keun KIM, Carla EMOLO, Andrea DEDENT
  • Publication number: 20160137736
    Abstract: The disclosure relates to a protein composed of a first polypeptide or polypeptide domain having a first specific binding activity for Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) expressed on a T-cell cell surface and a second specific binding activity for Glucose Transporter 2 (GLUT2) or an extracellular ectodomain thereof expressed on a pancreatic ?-cell surface, wherein binding of the first polypeptide or polypeptide domain to CTLA-4 induces a CTLA-4 specific agonist response in the T-cell, and binding of the second polypeptide or polypeptide domain to GLUT2 or an ectodomain thereof does not inhibit GLUT2 glucose transporter function, wherein said agonist response in the T-cell induces a response that reduces immunoreactivity against pancreatic ?-cells.
    Type: Application
    Filed: November 17, 2015
    Publication date: May 19, 2016
    Applicant: The Board of Trustees of The University of Illinois
    Inventors: Bellur S. PRABHAKAR, Chenthamarakshan VASU, Palash BHATTACHARYA
  • Publication number: 20160137776
    Abstract: In one aspect, block copolymers are described herein. A block copolymer described herein, in some embodiments, comprises a first block comprising a polymer or oligomer formed from the reaction product of (i) a polycarboxylic acid or a polycarboxylic acid equivalent, (ii) a polyol, and (iii) an amino acid; and a second block comprising a polymer or oligomer that differs from the polymer or oligomer of the first block. In some cases, the polycarboxylic acid or polycarboxylic acid equivalent comprises citric acid, a citrate, or an ester of citric acid. The polyol can comprise an ?,?-n-alkane diol, poly(ethylene glycol), or poly(propylene glycol). In some embodiments, the amino acid forms a pendant group of the polymer or oligomer of the first block and/or forms a luminescent 6-membered ring with the polycarboxylic acid or polycarboxylic acid equivalent. The second block of a block copolymer described herein, in some embodiments, comprises a polylactone.
    Type: Application
    Filed: July 8, 2014
    Publication date: May 19, 2016
    Applicants: Board of Regents, The University of Texas System, The Penn State Research Foundation
    Inventors: Jian Yang, Zhiwei Xie
  • Publication number: 20160136287
    Abstract: The present invention provides a composition for provoking an immune response in a patient to an autoantigen target, the composition comprising the target conjugated a carrier polypeptide.
    Type: Application
    Filed: October 27, 2015
    Publication date: May 19, 2016
    Applicant: The University of Birmingham
    Inventors: Kai-Michael Toellner, Roy Bicknell
  • Publication number: 20160140418
    Abstract: A disclosed modelling method includes: calculating a first function for generating data of a closed surface that contains plural points representing an annular structure in an object, based on positional information of the plural points; generating data of a first point set representing a boundary of the object, from tomographic image data; detecting data of points which are included in the first point set and located inside the closed surface by using the first function; removing the detected data of points from the data of the first point set to generate data of a second point set; calculating a second function for generating data of a shape of the object using the data of the second point set and data of the plural points; and storing data of the shape of the object, which is generated by using the second function, in the memory.
    Type: Application
    Filed: October 21, 2015
    Publication date: May 19, 2016
    Applicants: FUJITSU LIMITED, The University of Tokyo
    Inventors: Machiko NAKAGAWA, Masaki KAZAMA, Toshiaki HISADA, Seiryo SUGIURA, Takumi WASHIO, Jun-ichi OKADA
  • Patent number: 9339176
    Abstract: The invention is directed towards tools for use in performing surgery or examination via the oral cavity, in particular in the region of the oral cavity, oropharynx, larynx, and hypopharynx, devices and systems incorporating these tools, and procedures using these tools. More specifically, the tools, devices, systems and procedures are directed towards Transoral Robotic Surgery or any non-robotic transoral surgical approach.
    Type: Grant
    Filed: December 9, 2011
    Date of Patent: May 17, 2016
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: Gregory S. Weinstein, Bert W. O'Malley, Jr.
  • Patent number: 9343059
    Abstract: A system for reducing noise emissions in underwater environments is presented. The system can be extended to applications in any two-fluid environments where one fluid (gas) is contained in an enclosed resonator volume connected to the outside environment at an open end of the resonator body. The resonators act as gas-containing (e.g., air) Helmholtz resonators constructed into solid panels that are submerged in the fluid medium (e.g., sea water) in the vicinity of a noise generating source. The oscillations of the trapped air volume in the resonators causes reduction of certain noise energy and a general reduction in the transmitted noise in the environment of the system.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: May 17, 2016
    Assignee: Board of Regents, The University of Texas System
    Inventors: Preston Wilson, Kevin M. Lee, Mark S. Wochner, Hector L. Mendez Martinez
  • Patent number: 9342905
    Abstract: A disclosed display processing method includes: first generating data of a faying surface region between a first line element, for which a greatest radius is defined, and a second line element, for which a second greatest radius is defined, at a point where end points of plural line elements are connected, by using data of plural line elements for which a radius and coordinates of both end points are defined and data representing connection relationships between line elements; and second generating, for each line object of the plural line elements, data of a tubular object that is defined based on a faying surface region generated for the line element.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: May 17, 2016
    Assignees: FUJITSU LIMITED, The University of Tokyo
    Inventors: Masahiro Watanabe, Satoshi Fuchikami, Yoshimasa Kadooka, Toshiaki Hisada, Seiryo Sugiura, Takumi Washio, Jun-ichi Okada
  • Patent number: 9341604
    Abstract: The present disclosure provides adaptive methods for gas chromatography analysis of a gas sample comprising one or more target analytes (such as a micro-gas chromatography) and adaptive gas chromatography devices for carrying out such analytical methods. Broadly, the system can regulate flow into a downstream chromatographic column by detecting one or more upstream conditions. For example, one adaptive chromatography device comprises a first column, a modulator component, and a second column. A first detector or sensor detects the presence of target analytes upstream from the second column, while a second detector detects the presence of target analytes eluted from the second column. The modulator component assembly is responsive to an output generated by the first detector and adaptively regulates fluid flow into the second column. Such adaptive chromatography (micro-GC) systems have higher separation speed, better analyte identification capability, and far greater energy savings.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: May 17, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Xudong Fan, Yogesh B. Gianchandani, Jing Liu
  • Patent number: 9341589
    Abstract: A method and device for performing DNA sequencing and extracting structural information from unknown nucleic acid strands. The device includes a microwell structure, where identical DNA strands are immobilized within the microwell structure on a surface of a micro-bead, an active electrode or a porous polymer. The device further includes a CMOS-integrated semiconductor integrated circuit, where the CMOS-integrated semiconductor integrated circuit includes metal layers on a silicon substrate, where the metal layers form an active electrode biosensor. In addition, a sensing electrode is formed by creating openings in a passivation layer of the CMOS-integrated semiconductor integrated circuit to hold a single bead, on which the DNA strands are immobilized.
    Type: Grant
    Filed: June 20, 2012
    Date of Patent: May 17, 2016
    Assignee: Board of Regents, The University of Texas System
    Inventors: Arjang Hassibi, Arun Manickam, Rituraj Singh
  • Patent number: 9340269
    Abstract: A propeller shaft assembly having a propeller shaft member defining an inner volume. A foam liner member is disposed in at least a portion of the inner volume of the propeller shaft member. The foam liner member is made of a viscoelastic, natural oil polyol-based foam, whereby the foam liner member is operable to reduce vibration amplitudes occurring within the propeller shaft member relative to an undampened propeller shaft member.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: May 17, 2016
    Assignee: The Regents Of The University of Michigan
    Inventors: Alan Argento, Wonsuk Kim, Neil Nodelman, Louis Carlisle Glover, IV
  • Patent number: 9341921
    Abstract: A high-speed terahertz analog-to-digital converter (ADC) is provided. The ADC is comprised of an interferometer, a modulator and an array of detectors. The interferometer is configured to receive a carrier signal and guide a spoofed surface plasmon polariton (SSPP) wave in each of its two arms. The SSPP waves are emitted from the free end of each arm into a propagation space and combined in the space to form an interference wave. The modulator modulates the carrier signal in at least one of two arms with a modulating signal, where the radiation pattern of the interference wave in a far field of the propagation space is shifted in accordance with the amplitude of the modulating signal. The array of detectors are spatially separated from the interferometer by the propagation space and arranged to receive the interference wave.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: May 17, 2016
    Assignee: The Regents Of The University Of Michigan
    Inventors: Zhao Xu, Pinaki Mazumder
  • Patent number: 9339412
    Abstract: The present application relates to methods for maintaining core body temperature in a subject. Heat is applied to peripheral thermoregulatory control tissue of the subject to increase or maintain perfusion of blood in glabrous tissue of the subject, and a warming stimulus is applied to the glabrous tissue. The application of heat to the peripheral thermoregulatory control tissue occurs discretely and simultaneously with application of the warming stimulus to the glabrous tissue, without application of a heating device or a warming device to tissue other than the tissue subjected to the applied heat or to the applied warming stimulus, thereby maintaining the core body temperature of the subject.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: May 17, 2016
    Assignee: Board of Regents, The University of Texas System
    Inventors: Kenneth R. Diller, Daniel W. Hensley