Abstract: A medium composition for detection of P. carotovorum includes pectin, cellobiose, and inositol as active ingredients. P. carotovorum is highly likely to cause soft rot during cultivation as well as storage and transportation such that continuous monitoring is required. In order to solve the issues, the medium composition ensures remarkably outstanding selectivity for P. carotovorum.
Type:
Grant
Filed:
October 19, 2022
Date of Patent:
January 7, 2025
Assignee:
KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
Inventors:
Se-Wook Oh, Unji Kim, Ji Hye Baek, So-Young Lee
Abstract: The invention disclosed herein generally relates to methods and systems for converting stem cells into specific tissue(s) or organ(s) through directed differentiation. In particular, the invention disclosed herein relates to methods and systems for promoting vascularized human intestinal organoid tissue having an intestine-specific EC transcriptional signature from hindgut spheroid tissue produced in vitro from the described methods.
Type:
Grant
Filed:
May 27, 2021
Date of Patent:
January 7, 2025
Assignee:
The Regents of the University of Michigan
Abstract: The present disclosure provides compounds and methods for inhibiting a virus infection, such as a Baltimore Group IV RNA virus infection. Aspects of the present disclosure also include methods of treating a Baltimore Group IV RNA virus infection in a subject. The present disclosure also provides pharmaceutical compositions related to the same.
Type:
Grant
Filed:
September 22, 2022
Date of Patent:
January 7, 2025
Assignee:
The Governors of the University of Alberta
Inventors:
James A. Nieman, M. Joanne Lemieux, D. Lorne Tyrrell, Mostofa Hena, Appan Srinivas Kandadai, Alexandr Belovodskiy, Michael A. Joyce, Elena Arutyunova
Abstract: [Problem to be solved by the invention] The purpose of the present invention is to provide a competitive immunochromatographic analysis method and immunochromatographic sensor using said analysis method capable of intuitively displaying a molecular concentration of a substance to be measured and facilitating visual judgement of the molecular concentration.
Type:
Grant
Filed:
May 16, 2019
Date of Patent:
January 7, 2025
Assignees:
Techno Medica Co., Ltd., Keio University
Inventors:
Kazushi Misawa, Daniel Citterio, Hiroki Yamazaki, Tomohiro Yamamoto
Abstract: Disclosed herein are amphiphilic polymers and hierarchical structures (e.g., emulsions) comprising said polymer. Also disclosed herein are methods of using the polymers and hierarchical structure disclosed herein.
Type:
Grant
Filed:
May 20, 2020
Date of Patent:
January 7, 2025
Assignee:
The Regents of the University of California
Inventors:
Ellen M. Sletten, Daniel A. Estabrook, John O. Chapman
Abstract: A power divider includes first to third transmission lines (TLs) and first to third capacitors. The second TL includes a first transmission portion (TP) and a first output portion (OP). The first TP is connected between the first TL and the first OP. The third TL includes a second TP and a second OP. The second TP is connected between the first TL and the second OP. The first capacitor is connected between ground and a common node of the first TL and the first and second TPs. The second capacitor is connected between ground and a terminal of the first OP distal from the first TP. The third capacitor is connected between ground and a terminal of the second OP distal from the second TP.
Abstract: The present disclosure provides, inter alia, methods for treating cancers including leukemia using low doses of an anthracycline such as doxorubicin.
Type:
Grant
Filed:
June 26, 2020
Date of Patent:
January 7, 2025
Assignees:
Stowers Institute for Medical Research, The Children's Mercy Hospital, University of Kansas
Inventors:
Linheng Li, John M. Perry, Fang Tao, Xi C. He, Anuradha Roy, Scott J. Weir, Tara Lin
Abstract: In one or more embodiments, the present invention is directed to an electrically conductive polymer composition comprising a conductive metal filler material comprising a plurality of metal particles and one or more carbon-based filler material substantially homogenously dispersed throughout a polymer matrix, wherein the aspect ratio of the one or more carbon-based filler material is at least ten times greater than the aspect ratio of the conductive metal filler material comprising a plurality of metal particles. In one or more embodiment, the carbon-based filler material will comprise at least one of carbon nanotubes, multi-walled carbon nanotubes and edge-functionalized graphene.
Type:
Grant
Filed:
November 25, 2020
Date of Patent:
January 7, 2025
Assignee:
The University of Akron
Inventors:
Yu Zhu, Bryan D. Vogt, Clinton J. Taubert, Kun Chen
Abstract: A system and method for chat-based studies utilizing a plurality of users may be provided, utilizing at least one chat room processor and a plurality of remote processors. The chat room processors may be configured to receive a chat room template, create a plurality of chat rooms based on the chat room template, assign participants to one chat rooms, provide instructions associated with the chat room when all participants are present, provide questions or prompts at times defined by the chat room template or when conditions defined by the chat room template are met, collect all messages received from each participant, and storing information that includes the message, a time stamp the message was sent and/or received, and at least one unique identification code associated with the participant sending the message.
Abstract: The method includes: receiving an encoder signal and a ray machine output beam signal, and initially synchronizing the encoder signal and the ray machine output beam signal; recording coded value M of the encoder at moment tm, and coded value N of the encoder at moment tm+1, where M, N, and m are integers; determining that duration from the moment tm to the moment tm+1 is an actual output beam time interval T of the ray machine, when it is determined that a difference value between the coded value M and the coded value N satisfies preset value a, a being an integer; determining gap time TG in the actual output beam time interval T based on a preset output beam time interval TJ of the imaging system and the actual output beam time interval T; and controlling the ray machine not to emit beam within the gap time TG.
Type:
Grant
Filed:
November 4, 2022
Date of Patent:
January 7, 2025
Assignees:
Nuctech Company Limited, Tsinghua University
Inventors:
Zhiqiang Chen, Li Zhang, Yunda Sun, Zhenhua Zhao, Xin Jin, Le Shen, Wuyang Liang
Abstract: The present invention relates to a composition for regulating cell division by promoting or inhibiting the activity of FCHo1, and a method for regulating cell division using the same. The FCHo1 activity regulator of the present invention targets FCHo1 which functions as an important factor in cell division, and promotes or inhibits the activity thereof, thereby promoting cell division or inhibiting cell division, and thus can be effectively utilized for the treatment of diseases associated with cell division.
Type:
Grant
Filed:
November 17, 2016
Date of Patent:
January 7, 2025
Assignees:
Seoul National University R&DB Foundation, The IAC in Chungnam National University, UIC Group of Kyung Hee University
Inventors:
Myung Haing Cho, Sung Jin Park, Jong Sun Park, Kwang Pyo Kim
Abstract: Disclosed herein are IL-4 cytokine compositions with enhanced biological activity having increased selectivity for IL-4 cytokine receptors, and methods for their use. These compositions encompass interleukin-4 (IL-4) muteins. The disclosed methods encompass administering an IL-4 to treat neoplastic diseases, autoimmune diseases, infectious diseases or for expanding a hematopoietic cell population.
Type:
Grant
Filed:
August 7, 2020
Date of Patent:
January 7, 2025
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
K. Christopher Garcia, Darren L. Bates, Ignacio Moraga
Abstract: The present invention relates to an orthogonal-phase compound and its nonlinear optical (NLO) crystal of BaGa7Se7, its producing method and uses thereof. Polycrystalline orthogonal-phase BaGa4Se7 was prepared by a high-temperature solid-phase reaction in a sealed silica tube. Large size single crystals of orthogonal-phase BaGa4Se7 could be prepared by the flux method or Bridgman method. BaGa4Se7 crystallizes in the point group mm2. Orthogonal-phase BaGa4Se7 has a powder second harmonic generation (SHG) efficiency of about 5 times that of AgGaS2 and is phase-matchable. The orthogonal-phase BaGa4Se7 is non-hygroscopic and has good mechanical properties, which makes it easy to cut, polish, and coat by normal processing. The orthogonal-phase BaGa4Se7 crystal has never been cracked during cutting and polishing. The orthogonal-phase compound and NLO crystal of BaGa4Se7 can be used as NLO devices.
Type:
Grant
Filed:
August 24, 2021
Date of Patent:
January 7, 2025
Assignee:
Tianjin University of Technology
Inventors:
Hongwei Yu, Zhen Qian, Hongping Wu, Zhanggui Hu
Abstract: The disclosure includes embodiments of an apparatus, a device, and methods to transform an infant feeding bottle into an infant gavage feeding apparatus. According to an embodiment, an infant gavage feeding apparatus can include an infant feeding bottle, a gavage milk delivery component, a retaining ring, and a cord component. In another embodiment, infant milk dual-delivery device to transform an infant feeding bottle to an alternate nipple feeding and gavage feeding apparatus includes a gavage milk delivery component, a retaining ring, and a nipple receiving component. The gavage milk delivery component and the nipple receiving component can be positioned in a branched or a stacked configuration. The device can include a flow closure component and a controller to transition the milk flow for a gavage feeding and nipple feeding. The device can include a funnel to allow milk in the nipple to flow back into the infant feeding bottle.
Abstract: The present invention relates methods for treating cancer by comprising administering to the subject an agent for reducing at least one NEAA, inhibiting the PPP pathway, inhibiting the sorbitol pathway, inhibiting heme biosynthesis, or any combination thereof. The invention also includes methods of treating cancer comprising detecting a tumor as having increased ROS administering to the subject an agent for reducing at least one NEAA, inhibiting the PPP pathway, inhibiting the sorbitol pathway or inhibiting heme biosynthesis, or any combination thereof.
Abstract: Disclosed is a wearable motion capture glove based on a flexible optical fiber, relating to the field of motion capture. The wearable motion capture glove includes a glove body, multiple motion acquisition sensing devices, and a glove packaging tool. Each motion acquisition sensing device includes a data acquisition and processing module, a circuit splint, and a flexible polymer profiled optical fiber. The data acquisition and processing module includes a motion capture data acquisition module, and a motion capture data processing module. The flexible optical fiber and the motion capture data acquisition module are firmly packaged using the circuit splint and the glove packaging tool, and then are fixed to a corresponding position of a finger joint of a wearer, such that the glove can be worn more closely to the finger joint, and data acquisition is more stable and accurate.
Type:
Grant
Filed:
January 8, 2024
Date of Patent:
January 7, 2025
Assignee:
Nanchang Hangkong University
Inventors:
Bin Liu, Qi Wang, Xiyou Liang, Tiancheng Dong, Zijing Ding, Yuandong Xie, Mengdi Miao, Libo Tan, Yuxin Chen, Duo Xu, Qinyang Song
Abstract: A method for controlling a data center, comprising a plurality of server systems, each associated with a cooling system and a thermal constraint, comprising: a concurrent physical condition of a first server system; predicting a future physical condition based on a set of future states of the first server system; dynamically controlling the cooling system in response to at least the input and the predicted future physical condition, to selectively cool the first server system sufficient to meet the predetermined thermal constraint; and controlling an allocation of tasks between the plurality of server systems to selectively load the first server system within the predetermined thermal constraint and selectively idle a second server system, wherein the idle second server system can be recruited to accept tasks when allocated to it, and wherein the cooling system associated with the idle second server system is selectively operated in a low power consumption state.
Type:
Grant
Filed:
November 5, 2023
Date of Patent:
January 7, 2025
Assignee:
The Research Foundation for The State University of New York
Abstract: A multi-order diffractive Fresnel lens (MOD-DFL) that is suitable for use in a space telescope for studying transiting earth-like planets of distant stars is provided. The MOD-DFL may comprise a MOD-DFL array comprising a plurality of MOD-DFL segments that are secured to a mounting surface of a deployment device, such as a balloon, for example, in a preselected arrangement to form the MOD-DFL. An array telescope may be formed of an array of deployment devices, such as an array of balloons, for example, each having a MOD-DFL secured to a mounting surface of the respective deployment device, an optics system disposed inside of the respective deployment device, and a camera disposed inside of the respective deployment device. Each MOD-DFL comprises a plurality of MOD-DFL segments arranged in a preselected arrangement to form the respective MOD-DFL.
Type:
Grant
Filed:
June 28, 2019
Date of Patent:
January 7, 2025
Assignee:
ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
Inventors:
Thomas D. Milster, Daniel Apai, Lee C. Johnson
Abstract: Disclosed are a nickel-based superalloy formed by selective laser melting and a preparation method thereof. In the method, CrFeNb alloy powder is used as a grain refiner, and its element composition is within the composition range of a nickel-based superalloy powder to ensure that the prepared nickel-based superalloy has the same element composition with the original alloy; the grain size in the nickel-based superalloy could be refined by the addition of CrFeNb alloy powder, such that the anisotropic columnar grain structure in the alloy is transformed to equiaxed grain structure, thereby improving mechanical properties of the alloy.
Type:
Grant
Filed:
March 3, 2022
Date of Patent:
January 7, 2025
Assignee:
Northwestern Polytechnical University
Inventors:
Haijun Su, Yong Zhao, Meng Wang, Jun Zhang, Min Guo, Lin Liu, Hengzhi Fu
Abstract: Image security is becoming an increasingly important issue with the progress of deep learning based image manipulations, such as deep image inpainting and deep fakes. There has been considerable work to date on detecting such image manipulations using better and better algorithms, with little attention being paid to the possible role hardware advances may have for more powerful algorithms. This disclosure proposes to use a focal stack camera as a novel secure imaging device for localizing inpainted regions in manipulated images. Applying convolutional neural network (CNN) methods to focal stack images achieves significantly better detection accuracy compared to single image based detection.
Type:
Grant
Filed:
September 14, 2021
Date of Patent:
January 7, 2025
Assignee:
The Regents of The University of Michigan