Abstract: The invention relates to an ophthalmoscope comprising a camera and an associated illumination device; the invention further concerns a novel method for processing a plurality of images of the eye taken by said device; and software, typically included in said ophthalmoscope, for executing said method.
Type:
Application
Filed:
May 2, 2014
Publication date:
May 5, 2016
Applicants:
London School of Hygiene and Tropical Medicine, The Greater Glasgow Health Board, The University Court of the University of St Andrews
Inventors:
Stewart Jordan, Mario GIARDINI, Iain Livingstone, Andrew Bastawrous
Abstract: The present invention provides methods for fabricating field-effect devices and sensor arrays. The field of the invention also pertains to methods of using the sensors individually, in combination, and in array fashion to detect molecules. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention.
Type:
Application
Filed:
April 25, 2014
Publication date:
May 5, 2016
Applicant:
The Trustees of The University of Pennsylvania
Inventors:
Alan T. JOHNSON, Jin XI, Ganghee HAN, Mitchell LERNER, Jeffery G. SAVEN, Renyu LIU, Felipe MATSUNAGA, Jose Manuel PEREZ-AGUILAR
Abstract: In some embodiments, a compound and/or method of making a compound includes the modification of rheological properties of thermotropic main chain liquid crystalline polymers (LCPs) by melt state reactive processing. The modified liquid crystalline polymer may have an increased viscosity while retaining its liquid crystal properties.
Type:
Application
Filed:
May 13, 2014
Publication date:
May 5, 2016
Applicant:
Board of Regents, The University of Texas System
Abstract: Methods for identifying oncogenic biomarkers specific to a patient's cancer. Methods are also provided for identifying candidate therapeutic agents for treating a patient's cancer based on the oncogenic biomarkers. Methods for treating patient's having cancers that express mutant PIK3R1 and ras genes are also disclosed.
Type:
Application
Filed:
June 26, 2013
Publication date:
May 5, 2016
Applicant:
Board of Regents, The University of Texas System
Inventors:
Gordon B. MILLS, Yiling LU, Han LIANG, Wai Ting CHEUNG
Abstract: A mechanism is disclosed for transmitting pulses onto respective cables so that the pulses arrive at the remote ends of the respective cables in synchronized (or controllably asynchronized) fashion. First, the round-trip time of flight of each cable is measured using speedy delivery pulses, i.e., pulses whose leading edges have exponential shape. Second, a calculation is performed to determine the input delay(s) between the pulses that would produce desired output delay(s). For example, it may be desirable that the pulses arrive at the respective remote ends at the same time, in which case the desired output delay(s) is (are) zero. Third, the same speedy delivery pulses are transmitted onto the respective cables so that the interpulse delay(s) conform to the computed input delay(s). Thus, the desired output delay(s) are achieved at the remote ends of the cables.
Type:
Grant
Filed:
September 23, 2015
Date of Patent:
May 3, 2016
Assignee:
Board of Regents, The University of Texas System
Abstract: The present invention provides radiotherapeutic agents and compositions and methods for making and using the same. In some embodiments, the radiotherapeutic agent is a nanoparticle comprising a radionuclide and a carrier moiety. In some embodiments, the radionuclide is produced by activating a stable activatable particle via neutron activation.
Type:
Grant
Filed:
October 25, 2012
Date of Patent:
May 3, 2016
Assignee:
The University of North Carolina at Chapel Hill
Inventors:
Anthony J. Di Pasqua, Xiuling Lu, Michael Jay
Abstract: The present invention provides compositions for inhibiting the activity of an insect pest against a subject (or repelling an insect pest from an environment or preventing attraction to an environment) which compositions comprise geranylacetone as an active ingredient plus a carrier plus a further active ingredient selected from the list consisting of: 6-Methyl-hepten-2-one, octanal, plus optional other chemicals. Also provided are related materials and methods of use.
Type:
Grant
Filed:
March 2, 2007
Date of Patent:
May 3, 2016
Assignees:
The University Court of the University of Aberdeen, Rothamsted Research Limited
Inventors:
John Anthony Pickett, James George Logan, Michael Alexander Birkett, Anne Jennifer Mordue
Abstract: Optical methods, devices, and systems for noninvasively detecting transient surface displacements in a neuron are disclosed. Methods, devices, and systems provided may employ a phase-sensitive optical low coherence reflectometer. In addition, surface displacements due to action potential propagation in neural tissues may be detected in some embodiments using back-reflected light. According to some embodiments, exogenous chemicals or reflect ion coatings are not required. Transient neural surface displacement of less then 1 nm in amplitude and 1 ms in duration may be detected and may be generally coincident with action potential arrival to the optical measurement site. The systems and methods may be used for noninvasive detection of various neuropathies such as retinal neuropathies. They may also be useful in detecting the effects of various pharmacological agents.
Type:
Grant
Filed:
December 19, 2012
Date of Patent:
May 3, 2016
Assignee:
Board of Regents, The University of Texas System
Inventors:
Taner Akkin, Thomas E. Milner, Digant P. Dave, H. Grady Rylander, III
Abstract: A detector suitable for mass spectroscopy uses a thin membrane that converts the kinetic energy of impinging molecules into corresponding photons, the latter detected with a suitable photosensor. The arrival of molecules at the membrane is detected by detection of the corresponding photons.
Type:
Grant
Filed:
August 25, 2014
Date of Patent:
May 3, 2016
Assignees:
Wisconsin Alumni Research Foundation, University of Hamburg, The University of Massachusetts
Inventors:
Robert H. Blick, Jonathan Rodriguez, Hyunseok Kim, Zlatan Aksamija, Wolfgang Hansen, Christian Heyn
Abstract: Recommendation systems are widely used in Internet applications. In current recommendation systems, users only play a passive role and have limited control over the recommendation generation process. As a result, there is often considerable mismatch between the recommendations made by these systems and the actual user interests, which are fine-grained and constantly evolving. With a user-powered distributed recommendation architecture, individual users can flexibly define fine-grained communities of interest in a declarative fashion and obtain recommendations accurately tailored to their interests by aggregating opinions of users in such communities. By combining a progressive sampling technique with data perturbation methods, the recommendation system is both scalable and privacy-preserving.
Type:
Application
Filed:
January 6, 2016
Publication date:
April 28, 2016
Applicants:
AT&T Intellectual Property I, L.P., Board of Regents, The University of Texas System
Inventors:
Kadangode K. Ramakrishnan, Divesh Srivastava, Tae Won Cho, Yin Zhang
Abstract: There is provided an image processing apparatus which calculates a feature value of an image. The apparatus comprises first obtaining means for obtaining an image; calculation means for calculating a set of numerical values formed from degrees of contributions of each of a plurality of order, wherein the degree of contributions of each order indicate contributions of monomials of the order for intensity values which are calculated using an approximation polynomial, and wherein the approximation polynomial provides a relationship between a pixel position of the image and an intensity value at the pixel position and is formed from a plurality of the monomials each having an order out of the plurality of orders; and first output means for outputting the set of the calculated numerical values as the feature value of the image.
Type:
Grant
Filed:
September 26, 2012
Date of Patent:
April 26, 2016
Assignee:
Canon Kabushiki Kaisha and The University of Tokyo
Inventors:
Ryo Ishikawa, Kiyohide Satoh, Katsushi Ikeuchi, Bo Zheng, Yonggi Sun
Abstract: The invention provides a method and system for operating a solar farm inverter as a Flexible AC Transmission System (FACTS) device—a STATCOM—for voltage control. The solar farm inverter can provide voltage regulation, damping enhancement, stability improvement and other benefits provided by FACTS devices. In one embodiment, the solar farm operating as a STATCOM at night is employed to increase the connectivity of neighboring wind farms that produce peak power at night due to high winds, but are unable to connect due to voltage regulation issues. The present invention can also operate during the day because there remains inverter capacity after real power export by the solar farm. Additional auxiliary controllers are incorporated in the solar farm inverter to enhance damping and stability, and provide other benefits provided by FACTS devices.
Type:
Grant
Filed:
September 15, 2010
Date of Patent:
April 26, 2016
Assignee:
The University of Western Ontario
Inventors:
Rajiv Kumar Varma, Vinod Khadkikar, Shah Arifur Rahman
Abstract: In an example of a method for recovering lead from a lead material including lead sulfide, methane sulfonic acid is selected as a leaching acid for the lead material. The lead material is exposed to a solution including the methane sulfonic acid and i) ferric methane sulfonate or ii) oxygen, which leaches lead from the lead sulfide in the lead material, and generates a liquid leachate including a lead-methane sulfonate salt. The liquid leachate is purified, and lead is recovered from the purified liquid leachate using electrolysis.
Type:
Grant
Filed:
November 11, 2013
Date of Patent:
April 26, 2016
Assignee:
The University of British Columbia
Inventors:
Stefan Fassbender, David Dreisinger, Zhenghui Wu
Abstract: The present invention provides a novel lactate difference imaging (LDI) technique, allowing assessment of the metabolic responses of tissue over a period of time. This approach utilizes lactate change over a time period as an indicator of viable tissue, and offers benefits in the management and treatment of the effects of many common diseases, in particular stroke.
Type:
Grant
Filed:
September 3, 2010
Date of Patent:
April 26, 2016
Assignees:
Greater Glasgow Health Board, The University Court of the University of Glasgow
Inventors:
Celestine Santosh, William Holmes, Rosario Lopez
Abstract: Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein.
Type:
Grant
Filed:
January 5, 2015
Date of Patent:
April 26, 2016
Assignees:
Board of Regents, The University of Texas System, Arizona Board of Regents on behalf of the University of Arizona
Inventors:
Daruka Mahadevan, Emmanuelle J. Meuillet, Eugene A. Mash, Jr., Vijay M. Gokhale, Garth Powis, Shuxing Zhang
Abstract: Production of pore-free carbon/carbon-silicon carbide composite materials with mechanical properties making them suitable for use in such applications as the production of aircraft landing system brake components including brake discs. The method includes: providing a porous carbon-carbon composite preform; surrounding the porous carbon-carbon composite preform with silicon powder to form an intermediate construct; applying a uniaxial load to the construct; applying direct electrical current to an assembly containing the loaded construct of porous carbon-carbon preform surrounded by silicon powder, thereby melting the silicon powder and infiltrating the pores of the carbon-carbon preform with liquid silicon; and initiating a combustion-type reaction between the silicon and carbon in the preform, thereby forming silicon carbide in the preform.
Type:
Grant
Filed:
July 31, 2009
Date of Patent:
April 26, 2016
Assignees:
Honeywell International Inc., The University of Notre Dame du Lac
Inventors:
Manuel Koucouthakis, Douglas J. Steinke, Alexander Mukasyan, Jeremiah D. E. White
Abstract: This invention is in the fields of cancer therapy. More particularly it concerns compounds which are useful agents for inhibiting cell proliferative disorders, especially those disorders characterized by over activity and/or inappropriate activity of a EGFR, including EGFR-related cancers, and methods for treating these disorders.
Type:
Grant
Filed:
March 16, 2012
Date of Patent:
April 26, 2016
Assignee:
The Trustees Of The University Of Pennsylvania
Inventors:
Mark I. Greene, Hongtao Zhang, Alan Berezov, Zheng Cai
Abstract: The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel.
Type:
Grant
Filed:
May 14, 2014
Date of Patent:
April 26, 2016
Assignee:
Board of Regents, The University of Texas System
Abstract: In an example of a method for recovering lead from a mixed oxidized lead material, methane sulfonic acid is selected as a leaching acid for the mixed oxidized lead material. The mixed oxidized lead material is exposed to a solution including the methane sulfonic acid, which leaches lead from any of a lead oxide or a lead carbonate in the mixed oxidized lead material, and generates a liquid leachate including a lead-methane sulfonate salt. The liquid leachate is purified, and lead is recovered from the purified liquid leachate using electrolysis.
Type:
Grant
Filed:
November 11, 2013
Date of Patent:
April 26, 2016
Assignees:
The University of British Columbia, BASF SE
Inventors:
Stefan Fassbender, David Dreisinger, Zhenghui Wu