Abstract: An apparatus for measuring complex electrical admittance and/or complex electrical impedance in animal or human patients includes a first electrode and at least a second electrode which are adapted to be disposed in the patient. The apparatus includes a housing adapted to be disposed in the patient. The housing has disposed in it a stimulator in electrical communication with at least the first electrode to stimulate the first electrode with either current or voltage, a sensor in electrical communication with at least the second electrode to sense a response from the second electrode based on the stimulation of the first electrode, and a signal processor in electrical communication with the sensor to determine the complex electrical admittance or impedance of the patient.

Abstract: A method includes receiving toolface information corresponding to a location of the bottom hole assembly (BHA) with respect to a target drilling path and drift information. The surface steerable system calculates a first toolface vector from a first location of the BHA to the target drilling path to create a convergence path to the target drilling path and calculates an adjustment of the first toolface vector to a second toolface vector to account for system drift defined by the drift information such that the BHA will converge with the target drilling path by drilling in accordance with the second toolface vector. The surface steerable system modifies at least one drilling parameter to alter a drilling direction of the BHA based on the calculated second toolface vector and transmits the at least one drilling parameter to the drilling rig to target the BHA in accordance with the second toolface vector.

Abstract: This invention is in the fields of cancer therapy. More particularly it concerns compounds which are useful agents for treating cell proliferative disorders, especially those disorders characterized by over activity and/or inappropriate activity of a EGFR, including EGFR-related cancers, particularly for expanding the efficacy of drugs previously developed for this purpose, and for methods of treatments using the compounds for this purpose.

Abstract: The disclosure provides novel composite materials and methods for making such composite materials.

Abstract: Methods and systems are described for generating a data representation of a geographical region as an adjunct to conducting autonomous operations within the region. The method comprises receiving information specifying a plurality of localized caused zones having operation-defined geographical boundaries within the region; receiving heterogeneous data descriptive of the region; associating the received data with respective localized zones; fusing the received data associated with the localized zones into data representations of the localized zones; and integrating the data representations of the localized zones into a common data representation of the geographical region.

Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Abstract: The present invention provides methods of reducing or enhancing T cell activation and/or B cell activation in a subject, comprising administering to a subject an effective amount of an inhibitor or enhancer, respectively, of Semaphorin 6D (Sema6D) activity on T cells and/or B cells.

Abstract: The present invention generally relates to a method for computing a Fast Fourier Transform (FFT). In one embodiment, the present invention relates to an interleaved method for computing a Fast Fourier Transform (FFT).

Abstract: A system or methodology for converting thermal energy obtained from solar thermal, photovoltaic, geothermal or industrial waste heat into electrical power is disclosed. The energy efficient way of transferring two steams of liquid solutions containing different concentrations of ionic species is disclosed. The combination of thermal gradient in addition to concentration gradient to improve efficiency, reduce or avoid fouling is disclosed. This invention describes a method of efficient ion migration from concentrated stream to dilute stream thereby improving DC power generation process. The utilization of solar thermal energy from solar collector or concentrating photovoltaic (CPV) generator system or solar thermal power generation (CSP) system provides the additional driving force for ions transport from concentrated stream to dilute stream, apart from the concentration grading to generating power.

Abstract: The present invention provides materials and methods useful to treat various sGC?1-expressing cancers. Materials include peptides which interfere with sGC?1's pro-survival functions, thereby resulting in apoptosis of sGC?1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.

Abstract: A system for detecting ice or supercooled large droplets within an area of interest having a detection system measuring radiance or reflectance of the area of interest when exposed to shortwave infrared radiation having a wavelength in the range of about 2.05 ?m to about 2.30 ?m. The detection system measures the radiance or reflectance in a first band having a wavelength in the range of about 2.05 ?m to about 2.15 ?m and outputting a first band signal, and further measures the radiance or reflectance in a second band having a wavelength in the range of about 2.15 ?m to about 2.30 ?m and outputting a second band signal. A processing unit determines a ratio of the first band signal and the second band signal and compares the ratio to a predetermined critical ratio and outputs a determination signal indicating presence of ice or supercooled water droplets.

Abstract: The invention provides a spatially-selective reflective structure for the detection of submillimeter electromagnetic waves and systems and methods incorporating spatially-selective reflective structures. One aspect of the invention provides a spatially-selective reflective structure including a partially-conducting slab and a modulating reflector disk adjacent to the partially-conducting slab. The modulating reflector disk includes a plurality of modulations. Another aspect of the invention provides a submillimeter imaging device including submillimeter wave optics, a spatially-selective reflective structure located in the focal plane of the submillimeter wave optics, a submillimeter wave receiver positioned to capture waves reflected from the spatially-selective reflective structure, and a motor configured to rotate the spatially-selective reflective structure.

Abstract: Fabricating a nanofiber ribbon or sheet with a process that includes providing a primary assembly by arranging carbon nanotube nanofibers in aligned arrays, the arrays having a degree of inter-fiber connectivity, drawing the carbon nanotube nanofibers from the primary assembly into a sheet or ribbon, and depositing the sheet or ribbon on a substrate.

Abstract: Methods are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity.

Abstract: The present invention relates to compositions and methods for the preparation, stabilization, and/or storage of active agents, particularly therapeutic proteins and polypeptides such as Interleukin-2.

Abstract: Disclosed are various embodiments for a power stage that can drive various types of loads. The power stage includes a first capacitor and a second capacitor that are coupled to the load. The power stage also includes switches that are operable in a first power stage state and a second power stage state. When the switches are in the first power stage state, the first capacitor discharges to the load, and the second capacitor charges. When the switches are in the second power stage state, the second capacitor discharges to the load, and the first capacitor charges.

Abstract: A method, system and computer program product for efficiently identifying images, videos, audio files or documents relevant to a user. Using either manual annotations or learned functions, the method predicts the relative strength of an attribute in an image, video, audio file or document from a pool of images, videos, audio files or documents. At query time, the system presents an initial set of reference images, videos, audio files or documents, and the user selects among them to provide relative attribute feedback. Using the resulting constraints in the multi-dimensional attribute space, the relevance function for the pool of images, videos, audio files or documents is updated and the relevance of the pool of images, videos, audio files or documents is re-computed. This procedure iterates using the accumulated constraints until the top-ranked images, videos, audio files or documents are acceptably close to the user's envisioned image, video, audio file or document.

Abstract: A three-dimensional nanobattery formed by individually wiring nanostructured electrodes and combining them with an electrolyte. Short, capped nanotubes termed ‘nanobaskets’ are formed by sputtering coating onto nanoporous templates. Metallic nanowires are grown by electrochemical deposition from the nanobaskets and through the template, making electrical contact with each nanobasket electrode. The same procedure can be used to fabricate both a battery anode and a battery cathode. A thin layer of electrolyte is placed between the two nanobasket electrodes, and electrical contact is made through the nanowires.

Abstract: Provided are TCL1 peptides that bind to MHC I (HLA-A2) on tumor cells or other antigen-presenting cells and are recognized by T-cell receptors on T cells. The TCL1 peptides may be therapeutically used to treat a cancer, such as a B cell malignancy, leukemia, or lymphoma. Methods for expanding a population of T cells that target TCL1 are also provided.

Abstract: The present disclosure relates to valve replacement devices that are foldable for catheter-based deployment to the site of implantation, as well as systems for the delivery of valve prostheses, including prostheses having the special characteristics of the disclosed valve replacement devices. The devices include highly effective adhering mechanisms for secure and enduring precision implantation. The adhering mechanisms may employ a unique sealing mechanism that includes a cuff that expands slowly whereby the device is not secured in place until the completion of the implantation procedure. The implanted device, optionally together with the cuff, prevents perivalvular leaks and incorporate an appropriate leaflet system for reliable functioning in situ.