Abstract: Methods are disclosed herein for promoting survival of a donor liver in a recipient subject, wherein the donor liver is homozygous for rs738409:G mutation in the patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene. The method can include administering to the subject glutathione (GSH) and/or a nucleic acid molecule encoding a component of the ferroptosis pathway (such as GPX4).

Abstract: The present application provides a display panel and a manufacturing method thereof, the manufacturing method comprises: providing a first substrate, wherein a side of the first substrate is provided with a plurality of Micro-LED chips that are spaced apart from each other; providing a second substrate, wherein a surface on a side of the second substrate has a plurality of conductive layer parts; forming an isolation layer on the second substrate, wherein the isolation layer has a plurality of opening groups, each of the opening groups comprises a first opening and a second opening to expose a surface of one of the conductive layer parts, wherein a width of the first opening is greater than that of a P-type electrode, and a width of the second opening is greater than that of a N-type electrode; forming a first bonding layer in the first opening and forming a second bonding layer in the second opening; while supporting the chip body by the isolation layer, bonding the P-type electrode with the first bonding la

Abstract: The present disclosure provides an image sensing computing unit and its operating method, an image sensing computer and an electronic device. Among them, the image sensing computing unit includes a first photosensitive unit and a second photosensitive unit. The second photosensitive unit is connected in series with the first photosensitive unit. The changing direction of the first threshold voltage of the first photosensitive unit when receiving light is opposite to the changing direction of the second threshold voltage of the second photosensitive unit when receiving light, so as to implement an in-situ logical operation between light input signals.

Abstract: A quantum-key distributed (QKD)-enabled communication architecture it devises for networked microgrids (NMGs). A real-time QKD-enabled NMGs testbed built in an RTDS environment, and a novel two-level key pool sharing (TLKPS) strategy it designs to improve the system resilience against cyberattacks. In the QKD-based microgrid testbed design there is used a real-time power system simulator, i.e., RTDS, including the QKD modeling, hardware connection, communication network design, and QKD integration. By integrating QKD features into a real-time microgrid simulator, this testbed offers a flexible and programmable testing environment for evaluating the performance of QKD-enabled microgrids under a variety of scenarios.

Abstract: A method of predicting neural activation and psychopathology, indicative of ADHD and mood and anxiety disorders in a subject, such as children, is disclosed. The method may be implemented via computer software on a tablet computer, laptop or desktop computer, an input device, such as touchscreen, keyboard or mouse, and a camera. The camera is positioned to capture the subject's face in the frame of the camera. A frustration-inducing activity, such as a game, to the subject, where the subject received positive or negative feedback based on the selections they make in a game. The subject's reactions to the feedback are captured and parsed by the software, to determine the subject's emotional reaction to feedback. Reactions such as eye gaze, head pose, and facial expression may be used. Over a number of trials of the game, a prediction may be made for the neural activation and psychopathology of the subject.

Abstract: The present disclosure encompasses systems and methods for predicting embryo ploidy. Specific embodiments encompass methods of non-invasively predicting ploidy status of an embryo, by receiving a dataset with video including a plurality of image frames of the embryo, analyzing the plurality of image frames by one or more machine and/or deep learning model via one or more classification task applied to the dataset; and generating an output prediction of the ploidy status of the embryo. Particular methods relate to methods wherein the dataset additionally includes one or more clinical and/or morphological features for the embryo, such as maternal age at the time of oocyte retrieval. Embodiments also relate to predicting embryo viability and/or improving embryo selection, such as during in vitro fertilization, and uses thereof.

Abstract: First and second MRM transitions for a target substance, a first reference value concerning a measured intensity of the first MRM transition, and a second reference value concerning the measured-intensity ratio between the first and second MRM transitions are set. MRM measurements of an analyte sample using the first and second MRM transitions are performed to obtain a first intensity of the first MRM transition and a second intensity of the second MRM transition (Steps 11 and 12). The value of the first intensity is compared with the first reference value to determine whether the target substance is possibly contained (first determination; Step 14). For a target substance considered to be possibly contained in the analyte sample, the ratio between the first and second intensities is compared with the second reference value to determine whether the target substance is contained (second determination; Step 18).

Abstract: An electrolyte for a lithium battery containing a low concentration of gadolinium nitrate (Gd(NO3)3). In an electrolyte of 1 M lithium bis(trifluoromethanesulfonyl)imide (LiTFSI), DME:DOL (1:1), and 1% LiNO3, 1 mg/ml of Gd(NO3)3 as additive will promote the plating/stripping of lithium metal with nodular morphology and support dendrite suppression so that less dead lithium is formed on Li anode surface.

Abstract: Provided herein is an antisense oligonucleotide that specifically and selectively targets a mutant mRNA transcript of a cardiac myosin binding protein C (MYBPC3) allele having a 25 bp deletion (MYBPC3?25bp) within intron 32. Also provided are pharmaceutical compositions comprising the antisense oligonucleotides and a method of treating a cardiac disorder associated with a 25 bp deletion of MYBPC3 via administration of an antisense oligonucleotide according to the present disclosure.

Abstract: The present disclosure is directed to simple, scalable methods of forming colloidal MXene dispersions in nonpolar organic solvents with long term stability.

Abstract: A method for decoding an image signal according to the present invention may comprise the steps of: determining whether there is a brightness change between a current image including a current block and a reference image of the current image; if it is determined that there is a brightness change between the current image and the reference image, determining weight prediction parameter candidates for the current block; determining a weight prediction parameter for the current block on the basis of index information which specifies any one of the weight prediction parameter candidates; and performing a prediction on the current block on the basis of the weight prediction parameter.

Abstract: There is provided a method of setting exposure of a structured light 3-dimension (3D) camera generating a 3D image of an object. The method comprises setting at least one of exposure threshold values of the structured light 3D camera to capture images; receiving a first captured image from among the images the structured light 3D camera; calculating a first exposure time of the 3D camera based on the at least one of exposure threshold values; receiving a second captured image among the images from the structured light 3D camera; and calculating an optimal exposure time of the structured light 3D.

Abstract: The present disclosure relates to an apparatus for screening cathode active material candidates for secondary batteries, and may include a database constructing unit configured to receive a data-set labeled with properties of a cathode active material structure for secondary batteries; a pre-processing unit configured to pre-process a part of the data-set to a learning data-set; a prediction model generating unit configured to generate a cathode active material prediction model for predicting performance indicators of target materials that may be arranged to fit a predetermined structure based on the learning data-set; and a candidates generating unit configured to generate cathode active material candidates for secondary batteries based on a result of the cathode active material prediction model.

Abstract: A method is provided to reduce the counting times in radiation detection systems using machine learning, wherein the method comprises: receiving output data from a detector which is to detect a target material from a target body; analyzing the output data; identifying a material of interest from the analyzed output data; and controlling a source of the target material to prevent the source from harming the target body. An apparatus is also provided which comprises: a detector to detect radiation and to provide an output data in real-time; and a processor coupled to the detector, wherein the processor is to: receive the output data; analyze the output data; identify a material of interest from the analyzed output data; and control a source of the target material.

Abstract: A promoter activation sequence that allows for stable and efficient expression of a DNA of interest in a mammalian cell is provided. The promoter activation sequence has a nucleotide sequence represented by SEQ ID NO: 1, or a nucleotide sequence of 850 or more in a nucleotide sequence having 85% or higher sequence identity thereto. Also disclosed are an expression vector having the promoter activation sequence, a promoter, and a DNA of interest, a mammalian cell and a mammal including the expression vector.

Abstract: The present disclosure relates generally to methods for determining whether a patient suffering from or at risk for STXBP1- or SYNGAP1-encephalopathy will benefit from treatment with phenylbutyrate compositions comprising screening the patient for mutations in STXBP1 or SYNGAP1. Also disclosed herein are methods for selecting patients at risk for developmental and epileptic encephalopathy (DEE) for treatment with compositions including phenylbutyrate.

Abstract: A polypeptide based on RIP3 methylation modification and application thereof in cell necroptosis-related diseases are provided, belonging to the technical field of biomedicine. The polypeptide for inhibiting intestinal inflammatory injury (TAT-mRIP3-SDMA) is formed by connecting cell-penetrating peptide TAT and methylated RIP3 polypeptide.

Abstract: Systems and methods are provided for providing mental health intervention using a virtual environment. A spoken communication from a first user is conveyed to a second user in a virtual environment. Data about the first user is collected as the first user interacts with the second user. The collected data includes tone information from the spoken communication. A clinical parameter representing a mental state of the first user is determined from the collected data at a machine learning model. A prompt is provided to the second user, representing one of a suggested phrase, a suggested sentence, and a suggested topic of conversation, according to the determined clinical parameter.

Abstract: A nanomaterial and a method of preparing the nanomaterial are provided. The nanomaterial is a product formed by a reaction of functionalized carbon nanotube comprising first and second aminoalkyl groups covalently bonded to a surface of the carbon nanotube and a porphyrin ring of formula (I). A method of removing a pollutant from an aqueous solution by contacting the aqueous solution having an initial concentration of the pollutant with the nanomaterial is also provided.

Abstract: The present disclosure provides an optimal current selection method for a hybrid parallel integrated power supply, including the following steps: selecting multiple power device combinations with different current ratios, the combinations being formed by silicon insulated-gate bipolar transistor (Si IGBT) and silicon carbide metal-oxide-semiconductor field-effect transistor (SiC MOSFET) devices; comparing cost and junction temperatures on the Si IGBT devices and the SiC MOSFET devices under the different current ratios; comparing efficiency of a hybrid parallel integrated power supply with the different current ratios under different SiC MOSFET switching frequencies; comparing electromagnetic interference (EMI) noise of the hybrid parallel integrated power supply; selecting an optimal current ratio for the hybrid parallel integrated power supply.