Abstract: An energetic composition and a method of unzipping polymer binders are disclosed, which includes localizing a heat feedback just near the reaction front by unzipping polymer binders employed to a nanothermite. The energetic composition includes an unzipping polymer binder employed to high load fuel and oxidizer particles.

Abstract: A method for designing a knitted textile or fabric, the method includes receiving graphical input from a user regarding a knit pattern comprised of different types of individual stitches to be included in a textile or fabric design. The method further includes graphically displaying a representation of the textile or fabric design. The method further includes merging sections of continuous stitches of the same type into at least one block. The method further includes graphically displaying the textile or fabric design as a pattern of the at least one block. The method further includes applying edge rolling indicators and/or folding indicators to the displayed pattern of the at least one block, where the edge rolling and/or folding indicators respectively and graphically illustrate predicted edge rolling and folding behaviors of a physical textile or fabric.

Abstract: Systems and methods for neuronavigation in accordance with embodiments of the invention are illustrated. Targeting systems and methods as described herein can generate personalized stimulation targets for the treatment of mental conditions. In many embodiments, direct stimulation of a personalized the stimulation target indirectly impacts a brain structure that is more difficult to reach via the stimulation modality. In various embodiments, the mental condition is major depressive disorder. In a number of embodiments, the mental condition is suicidal ideation.

Abstract: Process and apparatus (10) are disclosed for capturing and converting an ozone-depleting alkyl halide fumigant from a fumigant/air mixed stream (14) by absorbing it into a metal hydroxide-alcohol buffer solution (26) in an absorber/scrubber (12) to produce a fumigant-free air stream (28). The captured alkyl halide in aqueous alcohol solution can actively react with the metal hydroxide in alcohol solution to produce a value-added product, such as a precipitate metal halide, and another alcohol that further enhances absorption. The absorbing solution is well-mixed with make-up alcohol and alkali streams to maintain the concentration of the metal hydroxide in the desired buffer solution range. The solid precipitate metal halide (52) is separated from the liquid stream, and the metal hydroxide-containing mixed alcohol stream (26) is recycled to the absorber/scrubber (12).

Abstract: The present application relates to compositions comprising and methods of using a liposome comprising a pHLIP polypeptide, wherein a lipid bilayer of the liposome is substantially free of the pHLIP polypeptide.

Abstract: The present invention relates to components, systems, and methods transcriptional modification (e.g., transcriptional activation) or methods of identifying transcriptional effectors based on Cas9-transcription effector fusion protein and gRNA sequence targeting.

Abstract: A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S)-1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S)-1-benzylisoquinoline alkaloid with the at least one enzyme converts the (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid.

Abstract: A method of providing optical coherence tomography (OCT) imaging may comprise using an on-chip frequency comb source interfaced with an OCT system by a circulator as an imaging source and reconstructing OCT images from resulting spectral data from target tissue illuminated by the imaging source.

Abstract: The present disclosure relates to a method for treating diabetic macular edema (DME) and/or retinal vein occlusion (RVO) comprising administering to the retina of a patient in need thereof an effective amount of a caspase-9 signaling pathway inhibitor. The caspase-9 signaling pathway inhibitor may include a peptide caspase-9 inhibitor and/or may be conjugated to a cell-penetrating peptide. The present disclosure further includes pharmaceutical compositions including a caspase-9 signaling pathway inhibitor. The disclosure further relates to the use of such compositions in a method for treating DME and/or RVO.

Abstract: Devices and methods are disclosed for remote clinical monitoring performance of exercises using an instrumented resistance device (100). An example device (100) includes a resistance band (120) having a first end (122) and a second end (124). A first handle (130) connected to the first end (122) and a second handle (140) connected to the second end (124) of the resistance band (120). The device (100) further includes a force sensing assembly (150) positioned between the first handle (130) and the first end (122). The force sensing assembly (150) includes a force sensor (156) connected to the resistance band (120), a microcontroller (182) connected to the force sensor (156) to receive a set of load force measurements from the force sensor (156), and a communication module (184) connected to the microcontroller (182) to transmit the set of load force measurements to a local data receiving device (170).

Abstract: In an embodiment, a method for completing measurements for a uniform linear array from measurements from a sparse linear array is provided. The method includes: receiving a first set of measurements for a sparse linear array by a computing device; generating a second set of measurements for a uniform linear array from the first set of measurements by the computing device; and using matrix completion to determine values for a plurality of missing elements of the generated second set of measurements for the uniform linear array by the computing device.

Abstract: Methods of making robust bijels include dispersing metal oxide precursors and/or metal salts into at least one phase of a bijel and hydrolyzing and condensing the metal oxide precursors and/or metal salts in a sol-gel reaction to form sintered bridges between interfacially jammed surface-active nanoparticles. The methods can be used with any bijels, including those produced during solvent transfer-induced phase separation (STRIPS) methods and other methods. A robust bijel includes chemically sintered bridges between the interfacially jammed surface-active nanoparticles. Methods of making nanocatalyst-functionalized sintered bijels include adsorbing metal salts to a surface of sintered interfacially jammed nanoparticles of bijels, and reducing the metal precursors on the surface of the sintered nanoparticles. Nanocatalyst-functionalized sintered bijels include catalytically active metal or metal oxide nanocatalysts on a surface of the sintered interfacially jammed surface-active nanoparticles.

Abstract: Aspects of various embodiments are directed to sensor apparatuses and methods thereof. An example sensor apparatus includes a capacitor and sensor circuitry. The capacitor includes a first substrate having a first electrode, a second substrate having a second electrode, and a dielectric layer. The dielectric layer has a plurality of dielectric structures arranged in a pattern, the first and second electrode being separated by the dielectric layer and arranged with an overlapping area with respect to one another. The sensor circuitry is coupled to the capacitor and configured and arranged to detect normal and shear forces applied to the sensor apparatus based on changes in capacitance derived from changes in at least one of a distance between first and second electrodes and the overlapping area of the first and second electrodes.

Abstract: Systems and methods may ethically evaluate intelligent systems operating in a real-world environment. The systems and methods may generate a clone of the intelligent system, and test the clone in a simulation environment. If the clone passes the testing, the systems and methods may permit the intelligent system to continue operating in the real-world environment. If the clone fails the testing, the systems and methods may override the intelligent system, such as disabling the intelligent system and assuming control in the real-world environment. The systems and methods may be implemented at a hardware level of a data processing device to prevent interference with the systems and methods by the intelligent system.

Abstract: A method for nanoscale tomographic infrared absorption imaging is provided, the method including: generating a first plurality of sets of probe measurements for a plurality of sample locations located across a surface of a sample, and measuring a magnitude and phase of a variation in displacement of the surface of the sample at the particular sample location at the second frequency, wherein the first frequency and the second frequency differ; and generating, based on the first plurality of sets of probe measurements, a three-dimensional tomographic map of absorption of infrared light at the first wavelength by the sample. Generating measurements for a particular location includes generating a first probe measurement by illuminating the sample with infrared light that varies at a first frequency and measuring a variation in displacement of the surface of the sample at the particular sample location at the first frequency.

Abstract: An improved alkaline pretreatment of biomass is provided that is a single-stage, two oxidant alkaline oxidative pretreatment process. The process uses a homogenous catalyst with at least two oxidants (Hydrogen peroxide and enhanced levels of oxygen) in an alkaline environment to catalytically pretreat lignocellulosic biomass in a single-stage oxidation reaction. The provided single-stage alkaline-oxidative pretreatment improves biomass pretreatment and increase enzymatic digestibility to improve the economic feasibility of production of lignocellulose derived sugars.

Abstract: Systems and methods are disclosed related to using acoustic waves to detect neural activity in a brain and/or localize the neural activity in the brain. Sensors positioned outside of a skull encasing the brain can detect acoustic waves associated with the neural activity in the brain. From output signals of the sensors, a particular type of neural activity (e.g., a seizure) can be detected. A location of the neural activity can be determined based on outputs of the sensors. In some embodiments, the ultrasound energy can be applied to the location of the neural activity in response to detecting the neural activity.

Abstract: Disclosed are novel compounds that accumulate in Gram-negative bacteria. Also disclosed are method of antimicrobial treatment using the compounds.

Abstract: A fault-tolerant quantum computing scheme implements quantum computing based on three-dimensional cluster states using just a small number of physical components. The technique may be implemented using a single actively controlled qubit [100], e.g., a quantum emitter, and a pair of delay line loops [106, 108], which can be physically realized using existing technologies in quantum photonic and phononic systems. A three-dimensional cluster state is prepared by using the actively con-trolled qubit to generate data qubits that propagate through the two delay line loops, interact with the actively controlled qubit, and then are measured by a detector [110].

Abstract: According to various embodiments, a method for detecting security vulnerabilities in a fifth generation core network (5GCN) is disclosed. The method includes constructing an attack graph from a plurality of regular expressions. Each regular expression corresponds to a sequence of system level operations for a known 5GCN attack. The method further includes performing a linear search on the attack graph to determine unexploited 5GCN attack vectors where path in the attack graph that does not represent a known 5GCN attack vector represents an unexploited 5GCN attack vector. The method also includes applying a trained machine learning module to the attack graph to predict new 5GCN attacks. The trained machine learning module is configured to determine a feasibility of linking unconnected nodes in the attack graph to create a new branch representing a new 5GCN vulnerability exploit.