Patents Assigned to University
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Patent number: 12237470Abstract: The invention belongs to the technical field of batteries, and discloses a phosphate-based flame-retardant electrolyte and a lithium-metal battery, and the phosphate-based flame-retardant electrolyte consists of a lithium salt, a phosphate solvent and a diluent. According to the invention, dimethyl (2-methoxyethoxy)methylphosphonate or diethyl (2-methoxyethoxy)methylphosphonate is used as a novel phosphate solvent, an electrolyte system with local high salt concentration is adopted, most phosphate solvent molecules are complexed with Li+ at the local high salt concentration by adjusting dosages of the lithium salt, the phosphate solvent and the diluent, so almost none of free solvent molecules exist, thus inhibiting irreversible decomposition of phosphate molecules on a surface of a li-anode, and meanwhile, the flame retardancy of the phosphate solvent greatly improves the safety of the lithium-metal battery.Type: GrantFiled: July 20, 2023Date of Patent: February 25, 2025Assignee: Nankai UniversityInventors: Jun Chen, Chunyu Zheng, Yuankun Wang, Yunpeng Hou, Zhenhua Yan, Haixia Li, Qing Zhao
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Patent number: 12234263Abstract: Provided herein are compositions related to vaccines, e.g., influenza vaccines, including, peptide based vaccines, nucleic acid based vaccines, recombinant virus based vaccines, antibody based vaccines, and virus based vaccines. Also provided herein are methods related to vaccines, e.g., influenza vaccines, including methods of identifying epitopes for the vaccines, producing, formulating, and administering the vaccines.Type: GrantFiled: June 30, 2023Date of Patent: February 25, 2025Assignees: InvVax, Inc., The Regents of the University of CaliforniaInventors: Arthur Young, Ren Sun, Nicholas C. Wu
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Patent number: 12234356Abstract: This document relates to epoxy compositions containing a sliding-ring polymer (polyrotaxane) additive and a thermally-curable epoxy resin. The epoxy compositions exhibit increased flexural toughness and impact resistance as compared to the same epoxy composition that does not contain the additive. This document also relates to 3D-printed epoxy compositions containing a sliding-ring polymer (polyrotaxane) additive and a thermally-curable epoxy resin.Type: GrantFiled: December 14, 2021Date of Patent: February 25, 2025Assignees: William Marsh Rice University, Saudi Arabian Oil CompanyInventors: Hasmukh A. Patel, Ali Zein Khater, Peter Boul, Pulickel M. Ajayan, Muhammad M. Rahman
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Patent number: 12234460Abstract: The present disclosure provides methods of treating a subject having decreased bone mineral density or at risk of developing decreased bone mineral density, and methods of identifying subjects having an increased risk of developing decreased bone mineral density.Type: GrantFiled: December 21, 2023Date of Patent: February 25, 2025Assignees: Regeneron Pharmaceuticals, Inc., The Royal Institution for the Advancement of Learning/McGill UniversityInventors: Jonas Bovijn, Olukayode Sosina, Sirui Zhou, Luca Andrea Lotta, Aris Baras, John Brent Richards
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Patent number: 12234732Abstract: The present disclosure provides a monitoring and warning device for rock burst in coal mine, which is configured for monitoring a rock mass in a drill hole, the monitoring and warning device for rock burst in coal mine includes: an integration rod, radial adjustment components, a plurality of bases, and a measuring instrument, the integration rod is extended into the drill hole; the radial adjustment components are provided on the integration rod, and have a plurality of radial adjustment ends; a plurality of bases are correspondingly provided in the radial adjustment ends, and the bases are further connected with attachment components through elastic components, and the attachment components are embedded with first strain gauges; the measuring instrument is rotatably provided in the integration rod, and is used to measure the distance between the measuring instrument and the attachment components.Type: GrantFiled: August 6, 2024Date of Patent: February 25, 2025Assignee: Henan Polytechnic UniversityInventors: Hongtu Zhang, Mian Wang, Zhibo Zhang, Chao Guo, Xiangyang Wang, Fenggang Zhang, Dong Chen, Pan Chen, Duzhou Li, Liuqun Du, Lianbo Huang, Jinhua Li, Junfang Li, He Sun, Zhen Li, Gongda Wang, Xu Chen, Weiyong Lu
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Patent number: 12235004Abstract: Systems and methods are disclosed for air flow optimization. In certain embodiments, the technology is a system comprising sensors, injectors, actuators, and a system processor. In order to optimize the air flow, the system processor directs the injectors to expel aerosol particles into an environment, such that the aerosol particles can be measured by the one or more sensors. Flow intensity map generation is then used to map the aerosol particles and air flow is changed to optimize aerosol particle concentration using the actuators.Type: GrantFiled: July 30, 2021Date of Patent: February 25, 2025Assignee: The George Washington UniversityInventors: Mark Reeves, Rahul Simha, Chen Zeng, Ali Eskandarian
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Patent number: 12232945Abstract: A Descemet Membrane Endothelial Keratoplasty (DMEK) holder for placement within a vial for supporting a corneal tissue inserter is provided. The DMEK holder includes a top and an opposite bottom, at least one support member extending between the top and the bottom, with a bottom portion of the at least one support member sized and shaped to fit against a bottom inner surface of the vial to thereby support the corneal tissue inserter within the vial, and a first annular member having an opening sized and shaped such that a bottom end of the corneal tissue inserter is insertable through the opening and the first annular member separates the corneal tissue inserter from an inner surface of the vial and positions the corneal tissue inserter within the vial away from inner surfaces of the vial to thereby improve retrieval of the corneal tissue inserter by a surgeon.Type: GrantFiled: June 28, 2021Date of Patent: February 25, 2025Assignee: University of Iowa Research FoundationInventors: Syed M. A. Muqsit Hashmi, Leela Raghava Jaidev Chakka, Aliasger K. Salem
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Patent number: 12236827Abstract: Systems and methods for a multi-primary color system for display. A multi-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. One embodiment of the multi-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.Type: GrantFiled: February 2, 2024Date of Patent: February 25, 2025Assignee: Baylor UniversityInventors: Mitchell J. Bogdanowicz, James M. DeFilippis, Corey P. Carbonara, Michael F. Korpi, Gary B. Mandle
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Patent number: 12238773Abstract: A frame transmission method, includes: sending, by a first communication end to a second communication end, a first RTS on an unlicensed channel, wherein the first RTS carries a licensed frequency band source indication; receiving, according to the licensed frequency band source indication, an assist-clear to send (A-CTS) that is sent by the second communication end in a retreat state on the licensed channel; and sending, according to the A-CTS, a first clear-request to send (C-RTS) on the unlicensed channel, wherein the first C-RTS is configured for instructing a third communication end to exit the retreat state entered based on the first RTS.Type: GrantFiled: November 29, 2019Date of Patent: February 25, 2025Assignees: Beijing Xiaomi Mobile Software Co., Ltd., Beijing University of Posts and TelecommunicationsInventors: Yajun Zhu, Wei Hong, Junli Li, Yong Li
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Patent number: 12233531Abstract: An animated figure system includes an animated figure comprising a flexible skin layer, an actuating system coupled to a connection location of the flexible skin layer, and an automation controller. The automation controller is configured to access a digital model of the animated figure, in which the digital model comprises a vertex associated with the connection location, determine a first positioning of the vertex within the digital model, and control the actuating system to set a second positioning of the connection location based on the first positioning of the vertex.Type: GrantFiled: March 25, 2020Date of Patent: February 25, 2025Assignee: Universal City Studios LLCInventors: Akiva Meir Krauthamer, Aaron Chandler Jeromin, Elam Kevin Hertzler
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Patent number: 12233073Abstract: An example technique for treating a skin cancer condition includes administering a therapeutically effective amount of a p53-related protein kinase (PRPK) inhibitor to a patient having skin cancer or having a high risk of developing skin cancer. An example composition includes a therapeutically effective amount of a PRPK inhibitor for treating a skin cancer condition. An example composition includes a pharmaceutically effective amount of at least one anti-solar ultraviolet (anti-sUV) combination for preventing a skin cancer condition. The at least one anti-sUV combination is chosen from the combinations: avobenzone and octinoxate; octocrylene and zinc oxide; avobenzone, octocrylene, and titanium dioxide; or avobenzone, octocrylene, and zinc oxide.Type: GrantFiled: June 8, 2018Date of Patent: February 25, 2025Assignee: Regents of the University of MinnesotaInventors: Ann M. Bode, Zigang Dong, Eunmiri Roh
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Patent number: 12234240Abstract: New synthetic methods to provide access to previously unexplored functionality at the C8 position of substituted imidazo[5,1-d][1,2,3,5]tetrazines of Formula I. Through synthesis and evaluation of a suite of compounds with a range of aqueous stabilities (from 0.5 to 40 hours), a predictive model for imidazotetrazine hydrolytic stability based on the Hammett constant of the C8 substituent was derived. Promising compounds were identified that possess activity against a panel of GBM cell lines, appropriate hydrolytic and metabolic stability, and brain-to-serum ratios dramatically elevated relative to TMZ, leading to lower hematological toxicity profiles and superior activity to TMZ in a mouse model of GBM.Type: GrantFiled: December 16, 2022Date of Patent: February 25, 2025Assignee: The Board of Trustees of the University of IllinoisInventors: Paul J. Hergenrother, Timothy M. Fan, Riley L. Svec
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Patent number: 12235564Abstract: A graphene structure includes one or more graphene layers. The graphene layers allow for microwave squeezing with gains up to 24 dB over a wide bandwidth.Type: GrantFiled: May 3, 2022Date of Patent: February 25, 2025Assignee: Abu Dhabi UniversityInventors: Montasir Yousof Abdallah Qasymeh, Hichem El Euch
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Patent number: 12234500Abstract: The present invention relates to compositions and methods for binding and detecting or measuring renalase. In one embodiment, the renalase binding molecule measures renalase amount or activity. Thus, in diseases and conditions where a measurement of renalase is beneficial, such renalase binding molecules may act as diagnostics.Type: GrantFiled: December 27, 2018Date of Patent: February 25, 2025Assignee: Yale UniversityInventors: Gary Desir, Jeffrey Testani, Veena Rao
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Patent number: 12236688Abstract: A method for tracking occluded objects includes encoding locations of a plurality of objects in an environment, determining a target object, receiving a first end point corresponding to a position of the target object before occlusion behind an occlusion object, distributing a hypothesis between both sides of the occlusion object during occlusion from a subsequent frame of the sequence of frames, receiving a second end point corresponding to a position of the target object after emerging from occlusion from another subsequent frame of the sequence of frames, and determining a trajectory of the target object when occluded by the occlusion object by performing inferences using a spatio-temporal probabilistic graph based on the current frame and the subsequent frames of the sequence of frames. The trajectory of the target object when occluded is used as a learning model for future target objects that are occluded by the occlusion object.Type: GrantFiled: May 6, 2022Date of Patent: February 25, 2025Assignees: Toyota Research Institute, Inc., The Regents of the University of California, Toyota Jidosha Kabushiki KaishaInventors: Pavel Tokmakov, Allan Jabri, Adrien D. Gaidon
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Patent number: 12234260Abstract: A Hepatitis E virus (HEV)-based virus like nanoparticle (HEVNP) made with a modified capsid protein containing at least a portion of open reading frame 2 (ORF2) protein conjugated with gold nanocluster is provided. Also provided are methods of targeted delivery of a nucleic acid using the HEVNP.Type: GrantFiled: September 27, 2022Date of Patent: February 25, 2025Assignee: The Regents of the University of CaliforniaInventors: R. Holland Cheng, Chun Chieh Chen, Mohammad Ali Baikoghli, Marie Stark
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Patent number: 12235492Abstract: A large-scale silicon-photonics-based optical switching system that occupies an area larger than the maximum area of a standard step-and-repeat lithography reticle is disclosed. The system includes a plurality of identical switch blocks, each of is formed in a different reticle field that no larger than the maximum reticle size. Bus waveguides of laterally adjacent switch blocks are stitched together at lateral interfaces that include a second arrangement of waveguide ports that is common to all lateral interfaces. Bus waveguides of vertically adjacent switch blocks are stitched together at vertical interfaces that include a first arrangement of waveguide ports that is common to all vertical interfaces. In some embodiments, the lateral and vertical interfaces include waveguide ports having waveguide coupling regions that are configured to mitigate optical loss due to stitching error.Type: GrantFiled: May 16, 2024Date of Patent: February 25, 2025Assignee: The Regents of the University of CaliforniaInventors: Tae Joon Seok, Ming Chiang A Wu
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Patent number: 12234575Abstract: Devices and methods for nanofiber-based membrane fabrication are provided. Portable (e.g., handheld) electrostatic spinning or electrospinning devices can be used for nanofiber-based membrane fabrication (e.g., wound care films or membranes, such as cannabidiol (CBD)-loaded films or membranes) and can be wearable and/or ultralow power. The device can include a needleless spinneret having solution supplied thereto and all powered by a low voltage battery.Type: GrantFiled: July 22, 2024Date of Patent: February 25, 2025Assignee: The Florida International University Board of TrusteesInventors: Arvind Agarwal, Omar Blandon Cruz, Lihua Lou
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Patent number: 12234316Abstract: The present invention discloses an acrylate oligomer, the acrylate oligomer is obtained by a reaction of isocyanate group-terminated oligomer and formate-terminated ethylene glycol methacrylate. After the acrylate oligomer provided by the present invention is photocured, the molecular structure, cross-linking density and other network structure characteristics of the acrylate oligomer can be changed through specific post-processing. Since the formate component formed after heat treatment has no water absorption and has a low glass transition temperature, the final material obtained after heat treatment has a lower water absorption rate and glass transition temperature. The present invention also provides a preparation method and an application method of the acrylate oligomer.Type: GrantFiled: April 17, 2022Date of Patent: February 25, 2025Assignee: Zhejiang UniversityInventors: Tao Xie, Jingjun Wu, Qian Zhao, Jiada Chen
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Patent number: 12232947Abstract: An IVC filter retrieval device useful for removing an IVC filter from a blood vessel, and useful for removing a tilted IVC filter causing the hook to be embedded in the side (wall) of a blood vessel from the blood vessel, and methods for using the same are described. The IVC retrieval device can be used to retrieve other foreign bodies such as, but not limited to, catheters and wires that may become detached from their devices and released into the blood vessels.Type: GrantFiled: September 14, 2022Date of Patent: February 25, 2025Assignee: The University of ToledoInventors: Munier Nazzal, Abdullah Nasif, Mohamed Fikri Mohamed Osman, Ayman Ahmed, Sakeena Davis, Soheila Alidad, Zahra Alzaher, Ghayth M. Ansarei