Abstract: A method for early diagnosis of keratoconus based on multi-modal data considers a mutual relationship between both eyes using four refractive maps for corneas of the both eyes and absolute corneal elevation data, and combines the deep convolutional network method, the traditional support vector machine (SVM) method in machine learning, and the elevation map enhancement method with adjustable best-fit-sphere (BFS) to identify sensitivity and specificity of a focus and balance the sensitivity and specificity. With multi-dimensional comprehensive judgment of a keratoconus morbidity with a patient as a unit, combined with binocular data including both manual selection features and deep network learning from big data, the diagnosis method has higher robustness and accuracy.

Abstract: A system and method for performing magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), or magnetic resonance spectroscopy imaging (MRS I) at multiple resonant frequencies using a coil system. The coil system includes at least one conductive loop and a capacitor forming a radiofrequency (RF) resonant antenna and a tuning-matching circuit electrically connected to the RF resonant antenna to operate at multiple resonant frequencies across a desired operational range. The coil system also includes two legs electrically connecting the tuning-matching circuit to the RF resonant antenna and having a length selected to generate at least two selected resonant frequencies with a selected frequency difference.

Abstract: The modified polypeptides include at least one amino acid substitution that allows the polypeptide to bind better to the S surface glycoprotein of coronaviruses that use ACE2 as a cell entry receptor, either through direct increases in affinity or through improved folding and expression of ACE2. Use of the modified ACE2 polypeptides for inhibiting CoV entry, replication and/or spread, for pre-exposure and post-exposure CoV prophylaxis, and for treating a CoV infection (e.g. COVTD-19), is also described.

Abstract: A neural ODE-based conditional tabular generative adversarial network apparatus includes: a tabular data preprocessing unit for preprocessing tabular data composed of a discrete column and a continuous column; a Neural Ordinary Differential Equation (NODE)-based generation unit for generating a fake sample by reading a condition vector and a noisy vector generated based on the preprocessed tabular data; and a NODE-based discrimination unit for receiving a sample composed of a real sample or the fake sample of the preprocessed tabular data and performing continuous trajectory-based classification.

Abstract: The present disclosure relates to a light-emitting diode (LED) structure, and more particularly, to an LED structure having an asymmetric face, a method of manufacturing a direct-current-drivable LED electrode assembly using the same, and a direct-current-drivable LED electrode assembly manufactured thereby.

Abstract: A display module includes: a glass substrate; a thin film transistor (TFT) layer provided on a front surface of the glass substrate, the TFT layer including a plurality of TFT electrodes; a plurality of light emitting diodes electrically connected to the plurality of TFT electrodes; and a plurality of through wiring members disposed at intervals along an edge area of the glass substrate and electrically connected to wirings on the front surface and a rear surface of the glass substrate, wherein each through wiring member of the plurality of through wiring members includes: a first conductive member provided on the front surface of the glass substrate; a second conductive member provided on the rear surface of the glass substrate; and a third conductive member penetrating through the glass substrate and having a first end provided on the first conductive member and a second end provided on the second conductive member.

Abstract: A generic inert bio-vector Salmonella sp. S9H and potential uses thereof are provided. The generic inert bio-vector Salmonella sp. S9H is derived from a continuous in-vitro culture of an inert bio-vector bacterium Salmonella sp. S9 by using LB solid and liquid culture media for passage to the fortieth generation. With a quantity of bacteria at a working concentration, the S9H does not cause non-specific agglutination reactions in sera or whole blood derived from humans, mice, cattle, pigs and poultry (including chickens, ducks, geese, turkeys, pigeons and quails); moreover, S9H has a property of carrying, and expressing and displaying different antigen factors derived from humans, mice, cattle, pigs and poultry (including chickens, ducks, geese, turkeys, pigeons and quails) on the surface thereof .

Abstract: An electrode includes an electrically conductive porous graphene core; a silicon layer disposed on an internal surface of the porous graphene core; and an ion-conductive hybrid silicate layer disposed on the silicon layer.

Abstract: The present invention relates to a laparoscopic surgery instrument that does not require a trocar, the laparoscopic surgery instrument including: a first part inserted into the body of the abdominal cavity and provided with a surgical instrument; and a second part placed outside the body of the abdominal cavity and coupled to the first part to manipulate the operation state of the surgical instrument, wherein the first part and the second part are primarily coupled to each other by magnetic force while the first part is inserted into the body.

Abstract: Systems and methods for performing long-term kinematic tracking of an animal subject are provided. Chronically-affixed motion capture markers including a tissue engaging feature and a reflective marker are described, the motion capture markers enabling long-term motion capture recording of an animal subject. A method of determining a three-dimensional pose of a subject using a trained statistical model configured to generate landmark position data associated with the three-dimensional pose of the animal subject. The method includes using projective geometry to generate three-dimensional image volumes as input to the trained statistical model. Further, a method for profiling a subject’s physical behavior over a period of time by applying clustering to information indicative of movement of the subject over the period of time is described.

Abstract: A user interface device based on proactive and reactive input quantification, includes a data acquisition unit configured to record input and screen output of a user, an input filtering unit for extracting an input timing for the input of the user, an output filtering unit for extracting an output timing to start a visual change beyond a specific reference for the screen output, an input/output interval extraction unit for generating a distribution of input/output intervals through timings for the input and the screen output of the user, and a model fitting unit for estimating proactiveness and reactiveness by adjusting the distribution of the input/output intervals to a proactive distribution and a reactive distribution.

Abstract: Provided is a novel agent capable of binding to a CUG repeat sequence. The agent comprises a compound A having a binding response of 10 resonance units (RU) or more at 25 nM to a (CUG)9 RNA immobilized at 401 RU as determined by surface plasmon resonance.

Abstract: Methods and devices for the prevention, treatment and diagnosis of cancer include assessing and quantifying imperfect dsDNA break repair. The methods may include determining a deletion signal for a DNA-containing sample of a subject, wherein the deletion signal comprises distributions of deletions (frequencies) of deletions with microhomologies of different lengths at the deletion sites in a DNA sequence or genome of the subject or sample thereof. The method may further include decomposing the deletion signal into components corresponding to changes arising from: (1) DNA repair processes, (2) systematic effects due to mapping personal deletion variants to reference genomes, and (3) false positive deletions generated during sample preparation, sequencing, and analysis, and quantifying these components to produce mutational signatures of defective HRR.

Abstract: A passive thermal management system and methods of using a thermoresponsive hydrogel coating configured to autonomously switch between a heating state and a cooling state based on ambient temperature. At temperature greater than a lower critical solution temperature of the thermoresponsive hydrogel, the thermoresponsive hydrogel coating becomes solar reflective and has enhanced radiative cooling ability to achieve daytime radiative cooling. At temperatures less than the lower critical solution temperature, the thermoresponsive hydrogel coating becomes transparent to facilitate absorption of solar radiation by sun absorber.

Abstract: A ripple push method for a graph cut includes: obtaining an excess flow ef(v) of a current node v; traversing four edges connecting the current node v in top, bottom, left and right directions, and determining whether each of the four edges is a pushable edge; calculating, according to different weight functions, a maximum push value of each of the four edges by efw=ef(v)*W, where W denotes a weight function; and traversing the four edges, recording a pushable flow of each of the four edges, and pushing out a calculated flow. The ripple push method explores different push weight functions, and significantly improves the actual parallelism of the push-relabel algorithm.

Abstract: A motor having multiple cooling flow channels, includes a housing, a stator, and a rotor. The stator comprises a winding. The housing comprises a cooling liquid inlet, an arc-shaped flow channel, and a cooling liquid outlet; the arc-shaped flow channel is defined around the housing and connected to the stator core; the rotor comprises a rotor flow channel; both the rotor flow channel and the arc-shaped flow channel are communicated with the cooling liquid inlet and outlet; and the rotor flow channel and the arc-shaped flow channel respectively correspond to two ends of the winding. A cooling liquid enters the arc-shaped flow channel for cooling the housing and a stator core of the motor, and enters the rotor flow channel for cooling the rotor. The cooling liquid flows through the rotor flow channel and the arc-shaped flow channel for respectively cooling the ends of the winding.

Abstract: The metal ceramic powder with a particle size of 15-45 µm and suitable for thermal spraying is prepared through a combination of mechanical ball milling, spray granulation, and vacuum sintering. The metal ceramic powder is sprayed on a surface of a steel substrate adopting the high velocity oxygen fuel (HVOF) technology with oxygen-propane as fuel and taking oxygen as a combustion improver, propane as fuel, nitrogen as powder feeding carrier gas, and air as a cooling medium to prepare and form the NiCrBSi—ZrB2 composite coating. The present disclosure solves the problem that ZrB2 ceramic is difficult to compact during sintering and improves powder bonding strength and fluidity. The preparation method is simple, has advantages of high coating deposition efficiency and convenient equipment operation, and is cost-effective. The preparation method can improve thermal corrosion resistance and high-temperature wear resistance of a surface of boiler, and prolonging lifetime of the boiler.

Abstract: The present disclosure provides a method for in-situ synthesizing tungsten carbide powder. In this method, cemented carbide scrap is used as an electrode and the molten salt electrolysis process is used to in-situ synthesize tungsten carbide powder, where a bidirectional pulse is used in the molten salt electrolysis process. In the method provided by the present disclosure, by using the bidirectional pulse and using the cemented carbide scrap as electrode in the molten salt medium, when the tungsten carbide scrap is oxidized, tungsten is dissolved in ionic form, deposited after the direction of current changes, and reacted with the carbon anode sludge in situ to generate tungsten carbide powder.

Abstract: Improved systems and methods are provided herein for extracting target speech from audio signals that can contain masking speech or other unwanted noise content. These systems and methods include detection of target speech in an input signal by detecting elevated frequency content in the signal above a threshold frequency. Portions of the signal determined to contain such elevated high frequency content are then used to generate audio filters to extract target speech from subsequently-obtained audio signals. This can include performing non-negative matrix factorization to determine a set of basis vectors to represent noise content in the spectral domain and then using the set of basis vectors to decompose subsequently-obtained audio signals into noise signals that can then be removed from the audio signals.

Abstract: The present invention provides a therapeutic and/or preventive agent for coronavirus disease 2019 (COVID-19) comprising 5-aminolevulinic acid (ALA) or its derivative or a salt thereof and provides a method for treating and/or preventing coronavirus disease 2019 (COVID-19) using the therapeutic and/or preventive agent.