Abstract: A soil-borne plant disease control agent that can be safely used as a biopesticide. The active component of the control agent includes viable bacteria of novel strains of Bacillus and Fictibacillus, or a culture of these bacteria. The soil-borne plant disease control agent is a vegetable wilt control agent. The plant disease control agent can be applied (sprayed) to stems and leaves to control a bacterial wilt disease caused by soil bacteria Ralstonia solanacearum species complex, and/or bacterial soft rots. A plant disease control method.

Abstract: Ultra-high field (“UHF”) magnetic resonance imaging (“MRI”) is used to localize the endopiriform nucleus (“EPN”) as a target for neuromodulation treatment. Single or multiple different image contrasts can be used to guide localization of the EPN. Treatment plan data are generated based on the localized EPN, and may include coordinate data, trajectory data, or both, for delivering neuromodulation treatment to the localized EPN.

Abstract: A pharmaceutical composition may be used in administering oxygen to a subject. The pharmaceutical composition may contain a perfluorocarbon dissolving oxygen therein. Further, a pharmaceutical composition may be used in decreasing the blood carbon dioxide partial pressure of a subject, and the pharmaceutical composition may contain a perfluorocarbon. Such a composition may be suitable for administered oral administration, nasogastric administration, trans-fistula gastric administration, or administration into a large intestine.

Abstract: A system and method for gene editing by using an engineered cell are provided. The system includes the engineered cell embedded with a synthetic protein receptor and a target cell. The engineered cell contains a CRISPR/CasRx system and a sgRNA gene sequence. The synthetic protein receptor includes an extracellular target cell recognition domain, a native Notch core domain, an intramembranous hydrolyzable polypeptide and effectors. The extracellular target cell recognition domain can recognize antigen molecules on the target cell surface; and the effectors act as transcription factors for CasRx enzyme and sgRNAs. CasRx and gRNA are expressed in the engineered cell for gene editing to edit mRNA of the target cell. In this way, the application range of the engineered cell is expanded, the pertinence and specificity of gene editing are improved, the off-target effect is reduced, the collective non-specific reaction is reduced, and the safety of gene editing is improved.

Abstract: Provided is a field effect transistor including a gate insulating layer having a two-dimensional material. The field effect transistor may include a first channel layer; a second channel layer disposed on the first channel layer; a gate insulating layer disposed on the second channel layer; a gate electrode disposed on the gate insulating layer; a first electrode electrically connected to the first channel layer; and a second electrode electrically connected to the second channel layer. Here, the gate insulating layer may include an insulative, high-k, two-dimensional material.

Abstract: A computer-implemented method of processing audio data, the method comprising receiving input audio data (x) comprising a time-series of amplitude values; transforming the input audio data (x) into an input frequency band decomposition (X1) of the input audio data (x); transforming the input frequency band decomposition (X1) into a first latent representation (Z); processing the first latent representation (Z) by a first deep neural network to obtain a second latent representation (Z{circumflex over (?)}, Z1{circumflex over (?)}); transforming the second latent representation (Z{circumflex over (?)}, Z1{circumflex over (?)}) to obtain a discrete approximation (X3{circumflex over (?)}); element-wise multiplying the discrete approximation (X3{circumflex over (?)}) and a residual feature map (R, X5{circumflex over (?)}) to obtain a modified feature map, wherein the residual feature map (R, X5{circumflex over (?)}) is derived from the input frequency band decomposition (X1); processing a pre-shaped frequency band

Abstract: Provided is a novel agent capable of binding to a CUG repeat sequence. The agent comprises a compound A having a binding response of 10 resonance units (RU) or more at 25 nM to a (CUG)9 RNA immobilized at 401 RU as determined by surface plasmon resonance.

Abstract: A non-transitory computer-readable recording medium stores therein an information processing program that causes a computer to execute a process including, deciding on one or more variables, from among a plurality of variables, to be a target for a question regarding degree of importance, based on order of priority of the variables and estimated amount, the order of priority of the variables being determined based on a plurality of patterns indicating ranking of the plurality of variables, the estimated amount indicating possibility of a match with predetermined condition regarding each of the patterns, and updating the estimated amount based on an answer result of the question about the decided variable.

Abstract: Methods and devices for the prevention, treatment and diagnosis of cancer include assessing and quantifying imperfect dsDNA break repair. The methods may include determining a deletion signal for a DNA-containing sample of a subject, wherein the deletion signal comprises distributions of deletions (frequencies) of deletions with microhomologies of different lengths at the deletion sites in a DNA sequence or genome of the subject or sample thereof. The method may further include decomposing the deletion signal into components corresponding to changes arising from: (1) DNA repair processes, (2) systematic effects due to mapping personal deletion variants to reference genomes, and (3) false positive deletions generated during sample preparation, sequencing, and analysis, and quantifying these components to produce mutational signatures of defective HRR.

Abstract: A method for breeding a new germplasm of clubroot-resistant orange-heading Chinese cabbage includes: (1) obtaining F1 by hybridizing orange-heading Chinese cabbage as a female parent and clubroot-resistant Chinese cabbage as a male parent, obtaining F2 by selfing F1 individual plants, planting F2 populations, and extracting DNA from the individual plants of F2; (2) observing horticultural traits of F2, and performing observation and statistics of head color phenotypic traits through cutting head; (3) performing PCR amplification with DNA of F2 using a dominant orange gene marker Br530 and a clubroot-resistant marker SC2930-T/SC2930Q, and identifying a genotype of the individual plants; (4) performing a comprehensive evaluation according to the results of marker detection and the observation of horticultural traits, selecting double-site homozygous clubroot-resistant orange-heading Chinese cabbage plants, and selfing the individual plants for 2 consecutive generations; and (5) obtaining a new germplasm of club

Abstract: The present invention provides a high-strength and high-plasticity titanium matrix composite and a preparation method thereof. The preparation method includes: preparing high-oxygen hydride-dehydride titanium powder using a high-temperature rotary ball grinding treatment process, in which the prepared hydride-dehydride titanium powder has a particle size of 10-40 ?m, and has an oxygen content of 0.8-1.5 wt. %; preparing high-purity ultra-fine oxygen adsorbent powder using a wet grinding method of high-energy vibration ball grinding treatment process; in which a purity of the oxygen adsorbent powder is ?99.9%, and a particle size of the oxygen adsorbent powder is ?8 ?m; mixing the high-oxygen hydride-dehydride titanium powder with the oxygen adsorbent powder in a protective atmosphere, and then press-forming the powder obtained after mixing to obtain a raw material blank; and performing atmosphere protective sintering treatment on the raw material blank to obtain a titanium matrix composite.

Abstract: The present disclosure provides a method for preparing a self-floating transparent nano ultrathin film. According to the present disclosure, the MXene film layer and the nano ultrathin film layer are sequentially subjected to suction filtration on the substrate material by utilizing a vacuum suction filtration technology, and thus a double-film structure is loaded on the substrate material; then an oxidant is subjected to oxidizing and bubbling on the MXene film layer in a permeation way, and thus the substrate material and the nano ultrathin film layer can be separated in a physical isolating manner. Finally, the nano ultrathin film is completely separated in a liquid phase floating separation manner. The nano ultrathin film prepared by the method provided by the present disclosure has a specific thickness and light transmittance through different loading capacities, and the substrate material can be repeatedly utilized.

Abstract: An amphibious robot is provided. An aspect of the robot includes an elongated flexible body, actuators in the flexible body and spaced apart along a length of the flexible body. The actuators are configured to move the flexible body in a serpentine or concertina motion on land and in water. An additional aspect includes a camera coupled adjacent to an end of the flexible body, at least one sensor coupled to the flexible body, and a buoyancy controller located in the flexible body. Another aspect includes a power source coupled to the flexible body and configured to power the actuators, the camera, the sensors, and the buoyancy controller. Yet another aspect employs an electric controller to control the actuators and receive data from the sensors.

Abstract: A programmable assembly of proteins into well-defined nanoworms with broadened stability regimes is disclosed. Posttranslational modifications (PTMs) were used to generate lipidated proteins with precise topological and compositional asymmetry. Using an integrated experimental and computational approach, the material properties (thermoresponse and nanoscale assembly) of these hybrid amphiphiles are modulated by their amphiphilic architecture. The judicious choice of amphiphilic architecture can be used to program the assembly of proteins into adaptive nanoworms that undergo a morphological transition (sphere-to-nanoworms) in response to temperature stimuli.

Abstract: Testing peptides in in vitro models of neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, Frontotemporal dementia, Amyotrophic lateral sclerosis, to evaluate systems and methods of treatment therefore.

Abstract: A scanning tunneling microscope including a z-axis scanning assembly; a quantum tunneling tip operatively connected to the z-axis scanning assembly; a z-axis controller configured to communicate with the z-axis scanning assembly; an x-y scanning assembly including a sample platform for holding a sample to be observed and arranged proximate the quantum tunneling tip separated in a z-axis direction from the platform; an x-y controller configured to communicate with the x-y scanning assembly; a measurement circuit connected to the quantum tunneling tip and the sample platform such that a relative electrical voltage is provided between said quantum tunneling tip and the sample platform and so as to measure an electrical current; and a data processor configured to communicate with the z-axis controller and the x-y controller to receive surface imaging information or point spectral information therefrom.

Abstract: The metal ceramic powder with a particle size of 15-45 µm and suitable for thermal spraying is prepared through a combination of mechanical ball milling, spray granulation, and vacuum sintering. The metal ceramic powder is sprayed on a surface of a steel substrate adopting the high velocity oxygen fuel (HVOF) technology with oxygen-propane as fuel and taking oxygen as a combustion improver, propane as fuel, nitrogen as powder feeding carrier gas, and air as a cooling medium to prepare and form the NiCrBSi—ZrB2 composite coating. The present disclosure solves the problem that ZrB2 ceramic is difficult to compact during sintering and improves powder bonding strength and fluidity. The preparation method is simple, has advantages of high coating deposition efficiency and convenient equipment operation, and is cost-effective. The preparation method can improve thermal corrosion resistance and high-temperature wear resistance of a surface of boiler, and prolonging lifetime of the boiler.

Abstract: The present disclosure provides a method for in-situ synthesizing tungsten carbide powder. In this method, cemented carbide scrap is used as an electrode and the molten salt electrolysis process is used to in-situ synthesize tungsten carbide powder, where a bidirectional pulse is used in the molten salt electrolysis process. In the method provided by the present disclosure, by using the bidirectional pulse and using the cemented carbide scrap as electrode in the molten salt medium, when the tungsten carbide scrap is oxidized, tungsten is dissolved in ionic form, deposited after the direction of current changes, and reacted with the carbon anode sludge in situ to generate tungsten carbide powder.

Abstract: Improved systems and methods are provided herein for extracting target speech from audio signals that can contain masking speech or other unwanted noise content. These systems and methods include detection of target speech in an input signal by detecting elevated frequency content in the signal above a threshold frequency. Portions of the signal determined to contain such elevated high frequency content are then used to generate audio filters to extract target speech from subsequently-obtained audio signals. This can include performing non-negative matrix factorization to determine a set of basis vectors to represent noise content in the spectral domain and then using the set of basis vectors to decompose subsequently-obtained audio signals into noise signals that can then be removed from the audio signals.

Abstract: A carbon nanomaterial for gas storage and a method for manufacturing the same are provided. The specific surface area of the carbon nanomaterial for gas storage is greater than 2000 m2/g. The mesopore volume of the carbon nanomaterial for gas storage is greater than the micropore volume of the carbon nanomaterial for gas storage, and the carbon nanomaterial for gas storage has a peak intensity ratio (ID/IG) between G band and D band, as determined from the Raman spectrum, between 1.1 and 2. In the carbon nanomaterial for gas storage, the pore volume of pores with a pore width of 6 nm or less is bigger than that of pores with a pore width greater than 6 nm.