Patents Assigned to University
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Patent number: 11225459Abstract: Disclosed is a composition and method for a therapeutic treatment that is able to combat neuroinflammation caused by diseases and disorders such as Alzheimer's disease, Parkinson's disease, and traumatic brain injury. The class of urea compounds acts by blocking at targeted receptors in the brain that contribute to the increase in inflammation. Combinations of receptors, H1 receptor, H2 receptor, dopamine transporter (DAT), and/or 5HT3C receptor, are individually and/or collectively inhibited by the same compositions of the present disclosure, and this ability leads to a decrease in brain edema. The DAT inhibitory effects additionally maintains dopamine levels in a patient.Type: GrantFiled: August 9, 2018Date of Patent: January 18, 2022Assignee: Texas Tech University SystemInventors: Nadezhda German, Mikelis Constantinos
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Patent number: 11224389Abstract: The present invention relates generally to X-ray detectors and more particularly to a system and a method for integrating an anti-scattering grid with scintillators to significantly enhance the performance of flat panel X-ray detector. In particular, the performance of a flat panel X-ray detector may be enhanced by photon counting detector pixels configured underneath the septa of a 2D antiscatter grid.Type: GrantFiled: April 13, 2018Date of Patent: January 18, 2022Assignee: The Regents of the University of Colorado, a body corporateInventor: Cem Altunbas
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Patent number: 11227438Abstract: A system configured to facilitate virtual outfit fitting is described. The system includes a smart closet device having components including a display door and a plurality of image sensors. A first image sensor of the plurality of image sensors is configured to move across a horizontal axis and a vertical axis of enclosure of the smart closet device to capture a plurality of images of a first outfit hung on an outfit hanging column. The smart closet device also includes a computing unit to generate a three-dimensional (3D) model of the first outfit based on the plurality of images. The computing unit is further configured to update an outfit database by storing the generated 3D model of the first outfit in an outfit database. The computing unit generate an image of a user wearing the output in response to receiving a selection of the first output from the user.Type: GrantFiled: August 30, 2021Date of Patent: January 18, 2022Assignee: King Abdulaziz UniversityInventors: Tala Hashem Mohammed Alhebshi, Laila Ahmed Salim Bahammam
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Patent number: 11225927Abstract: An air-fuel ratio control system for a hybrid vehicle engine is provided, including a torque coordination calculation module, which converts a target effective torque of a hybrid power control unit into a target indicated torque; a torque estimation module, which obtains an estimated indicated torque according to an operating state of an engine; an air-fuel ratio feedback control module, which generates a feedback correction factor based on deviation between the estimated indicated torque and the target indicated torque; and an air-fuel ratio feedforward control module, which converts the target indicated torque into an air-fuel ratio feedforward control signal according to a calibration parameter and engine speed. A target air-fuel ratio is obtained by correcting the air-fuel ratio feedforward control signal, via the feedback correction factor; and the target air-fuel ratio is configured to act on the engine to achieve air-fuel ratio control.Type: GrantFiled: March 11, 2021Date of Patent: January 18, 2022Assignee: TONGJI UNIVERSITYInventors: Diming Lou, Liang Fang, Piqiang Tan, Yunhua Zhang, Zhiyuan Hu, Yafeng Shi
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Patent number: 11227964Abstract: Luminescent solar concentrators in accordance with various embodiments of the invention can be designed to minimize photon thermalization losses and incomplete light trapping using various components and techniques. Cadmium selenide core, cadmium sulfide shell (CdSe/CdS) quantum dot (“QD”) technology can be implemented in such devices to allow for near-unity QDs and sufficiently large Stokes shifts. Many embodiments of the invention include a luminescent solar concentrator that incorporates CdSe/CdS quantum dot luminophores. In further embodiments, anisotropic luminophore emission can be implemented through metasurface/plasmonic antenna coupling. In several embodiments, red-shifted luminophores are implemented. Additionally, top and bottom spectrally-selective filters, such as but not limited to selectively-reflective metasurface mirrors and polymeric stack filters, can be implemented to enhance the photon collection efficiency.Type: GrantFiled: August 27, 2018Date of Patent: January 18, 2022Assignees: California Institute of Technology, The Regents of the University of California, The Board of Trustees of the University of IllinoisInventors: David R. Needell, Noah Bronstein, Armand P. Alivisatos, Harry A. Atwater, Ralph Nuzzo, Haley Bauser, Ognjen Ilic, Junwen He, Lu Xu, Colton Bukowsky, Sunita Darbe, Zach Nett, Brent Koscher
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Patent number: 11227143Abstract: An automatic classification method of whole slide images (WSIs) for cervical tissue pathology based on confidence coefficient selection. The automatic classification method includes steps: S1: dividing the WSIs for the cervical tissue pathology into small pieces having set size, gathering the small pieces of each WSI into a packet, and removing blank pieces in the packets; S2: building a deep CNN model; S3: training the deep CNN for designated rounds; S4: performing sequential arrangement and connection to obtain feature vectors of WSIs by using the trained deep CNN as the feature extractor; S5: training a support vector machine classifier; and S6: processing the WSIs for the cervical tissue pathology, to be classified, through step S1 and step S4 to obtain the feature vectors of the images, and inputting the feature vectors into the trained support vector machine classifier to realize classification.Type: GrantFiled: September 21, 2020Date of Patent: January 18, 2022Assignee: Wuhan UniversityInventors: Juan Liu, Zhuoyu Li, Jing Feng, Zhiqun Zuo
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Patent number: 11228039Abstract: The disclosure relates to solid oxide fuel cell (SOFC) anode materials that comprise various compositions of chromate based oxide materials. These materials offer high conductivity achievable at intermediate and low temperatures and can be used to prepare the anode layer of a SOFC. A method of making a low- or intermediate-temperature SOFC having an anode layer comprising a chromate based oxide material is also provided.Type: GrantFiled: September 25, 2018Date of Patent: January 18, 2022Assignee: University of Maryland, College ParkInventors: Mohammed Hussain Abdul Jabbar, Eric D. Wachsman, Ke-Ji Pan
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Patent number: 11228755Abstract: According to the present invention, provided is a method of processing a video signal, the method including: obtaining a transform coefficient of a current block from a bitstream according to a predetermined scanning order; determining an intra prediction mode of the current block on the basis of the transform coefficient; and performing intra prediction on the current block using the intra prediction mode and a neighboring sample adjacent to the current block.Type: GrantFiled: March 17, 2017Date of Patent: January 18, 2022Assignee: Industry Academy Cooperation Foundation of Sejong UniversityInventors: Yung Lyul Lee, Nam Uk Kim
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Patent number: 11224372Abstract: An implantable electrode for use in the body of a subject has a metal layer and a graphene passivation layer formed on at least a portion of the metal layer. The graphene passivation layer may be a single monolayer of graphene. A process for passivating an implantable electrode is also disclosed.Type: GrantFiled: January 6, 2015Date of Patent: January 18, 2022Assignee: The Trustees of the University of PennsylvaniaInventors: Duygu Kuzum, Ertugrul Cubukcu, Brian Litt
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Patent number: 11224880Abstract: A laboratory flask holder, comprising a holder portion configured to receive a laboratory flask, a frame connected to the holder portion, wherein the holder portion is configured to pivot about the frame such that a liquid may be dispensed from the laboratory flask without moving the frame, a temperature sensor arranged on the holder portion configured to determine a temperature of a liquid in the laboratory flask, and a display for providing an indication of the temperature of the liquid is provided. Methods of using the flask holder and a dispensing system are also provided.Type: GrantFiled: December 22, 2020Date of Patent: January 18, 2022Assignee: KING ABDULAZIZ UNIVERSITYInventors: Nawal Ghurmullah Hassan Almalki, Salah Eldin Mohamed Abu Aba
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Patent number: 11224872Abstract: A pipette based on surface charges includes a pipette body. A plurality of support rods are provided below the pipette body. Connecting rods are provided at the lower ends of two adjacent support rods. A substrate is provided between the connecting rods. A porous SiO2 coating is provided on the substrate. A hydrophobic molecule layer is provided on the surface coating by the vapor deposition method. A superamphiphobic surface is formed on the substrate by the surface coating and the hydrophobic molecule layer. The substrate and the surface coating are made of dielectric materials. A circular limit plate is provided above the pipette body. The pipette body, the support rods, the connecting rods and the limit plate are integrally formed, and are electrically non-conductive. An electrically conductive sliding rod is movably provided within the pipette body and the limit plate.Type: GrantFiled: September 19, 2019Date of Patent: January 18, 2022Assignee: UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINAInventors: Xu Deng, Qiangqiang Sun, Yu Zhou
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Patent number: 11225499Abstract: A chiral platinum complex having a chemical formula (I): A method for synthesizing the chiral platinum complex (I), includes: dissolving 0.700 g of Pt(DMSO)2(NO3)2 in 30 mL of dichloromethane as a solvent to yield a solution; adding 0.450 g of 1,4-(4R)-diphenyl-2-oxazolinyl benzene to the solution, and reflux a resulting mixture for reaction for 48 hrs, and stopping the reaction; filtrating reaction products; and adding dichloromethane and petroleum ether, and naturally volatilizing to yield a binuclear platinum complex single crystal. A method for condensation of benzophenone imine and trimethylsilitrile by using the chiral platinum complex as a catalyst. A method for treating cancer includes administering the chiral platinum complex to a patient in need thereof. The cancer includes: lung cancer (A549), nasopharyngeal carcinoma (KB), anti-drug-resistant nasopharyngeal carcinoma (KB-VIn), and human breast cancer (MCF-7).Type: GrantFiled: September 16, 2020Date of Patent: January 18, 2022Assignee: HEFEI UNIVERSITY OF TECHNOLOGYInventor: Mei Luo
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Patent number: 11224645Abstract: Certain embodiments are directed to an immunogenic composition comprising an immunogenic glycoconjugate comprising a glycan having the chemical formula of galactopyranose (Galp)-?(1,2)-R, Galp-?(1,3)-R, Galp-?(1,4)-R, or Galp-?(1,6)-R, wherein in R is any monosaccharide, oligosaccharide, or polysaccharide, coupled to a carrier peptide or protein. Certain aspects described herein are directed to compounds and therapies for treating Leishmania infections.Type: GrantFiled: March 22, 2016Date of Patent: January 18, 2022Assignee: Board of Regents, The University of Texas SystemInventors: Rosa Maldonado, Igor Almeida, Katja Michael, Eva Adriana Iniguez
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Patent number: 11225628Abstract: The present invention relates to a coating composition that can produce an article having an inner surface and an outer surface, both of which are slippery, and a method for preparing the same. By using the coating composition according to the present invention, it is possible to produce the article having the inner surface and the outer surface, both of which are slippery, only with a simple process of molding and curing a polymer resin by the technique of the prior art. The article produced using the coating composition of the present invention can solve an ice removal on a surface of the machinery such as an aircraft and an automobile, a biofouling problem in a blood vessel, a problem requiring self-cleaning, and the like, and thus can be used in various industries.Type: GrantFiled: October 17, 2018Date of Patent: January 18, 2022Assignee: Industry-University Cooperation Foundation Hanyang UniversityInventors: Dong Rip Kim, Kang Won Lee, Ji Hoon Ahn, Yale Jeon
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Patent number: 11225675Abstract: The present invention provides D-lactate dehydrogenase, an engineered strain containing the D-lactate dehydrogenase and a construction method and use of the engineered strain. The present invention discloses a D-lactate dehydrogenase which has unique properties and is from Thermodesulfatator indicus, and the D-lactate dehydrogenase has good thermophily and heat stability. By using the D-lactate dehydrogenase and the gene engineering reconstruction method, a fermentation product of the reconstructed Bacillus licheniformis can be redirected to optically-pure D-lactic acid with a high yield from naturally produced 2,3-butanediol, and the optical purity of the produced D-lactic acid reaches 99.9%; and raw materials for fermentation are low-cost, and a fermentation state is between an anaerobic fermentation state and a microaerobic fermentation state.Type: GrantFiled: June 24, 2020Date of Patent: January 18, 2022Assignee: Shanghai Jiao Tong UniversityInventors: Ping Xu, Chao Li, Fei Tao, Hongzhi Tang
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Patent number: 11226076Abstract: This invention presents a solar light collecting and guiding system for stabilizing the output light intensity, wherein the system comprising an array of converging lenses and optical fibers for collecting light focused by converging lenses. The fibers and the lenses are in one-to-one correspondence wherein the input end of an optical fiber is located in the focus position of the corresponding converging lens, and the axis of the optical fiber overlaps with the principal axis of the corresponding converging lens. The system is equipped with a sunlight tracking positioning device for synchronized motion, wherein the device is applied to tracking the sun light ray vertical incident into the central converging lens. The system has the function of outputting stable light intensity, that is, it can effectively reduce the variation of the collecting efficiency caused by the positioning deviation between the incident angle of sunlight and the designed input angle.Type: GrantFiled: March 23, 2018Date of Patent: January 18, 2022Assignee: JIANGSU UNIVERSITYInventors: Mingyang Chen, Xiaoming Xu, Ling Wang
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Patent number: 11225644Abstract: A method for culturing cells by which the diameter of cell aggregates can be controlled, and by which a large amount of cells can be obtained, a cell aggregate obtained by the method, a cell aggregation control agent, and a medium containing the cell aggregation control agent, are provided. A method for culturing cells by suspension culture, which method includes an aggregation control step of adding a substance that inhibits a cell adhesion molecule(s) of the cells to a medium to control cell aggregation of the cells, and the like are provided.Type: GrantFiled: January 27, 2016Date of Patent: January 18, 2022Assignees: SOMAR CORPORATION, THE UNIVERSITY OF TOKYOInventors: Yasuyuki Sakai, Ikki Horiguchi, Kumiko Matsunaga, Shunji Hayasaka
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Patent number: 11228113Abstract: A wide-beam planar backfire and bidirectional circularly-polarized antenna. An entire planar sectorial magnetic dipole is of a semi-closed structure, the planar sectorial magnetic dipole comprises two identical sectorial patches and a vertical short-circuit wall, and the vertical short-circuit wall is connected with straight sides of the two sectorial patches along a radial direction of the planar sectorial magnetic dipole; two sets of concentric annular electric dipoles are respectively used as a top concentric annular radiating element and a bottom concentric annular radiating element, as well as a top concentric annular reflector and a bottom anti-concentric annular reflector; and the top concentric annular radiating element is connected with an upper surface of the planar sectorial magnetic dipole through a top connecting branch, and the bottom concentric annular radiating element is connected with a lower surface of the planar sectorial magnetic dipole through a bottom connecting branch.Type: GrantFiled: October 25, 2018Date of Patent: January 18, 2022Assignee: Nanjing University of Posts and TelecommunicationsInventors: Wenjun Lv, Yun Shao, Leijie Wang, Zhuang Li, Weili Zhang, Shanshan Gu, Hongbo Zhu
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Patent number: 11226334Abstract: [Problem] To provide a method for detecting high-risk prostate cancer, for the purpose of providing useful information, such as necessity of biopsy, to a test-positive patient in a PSA test. [Solution] The method for detecting high-risk prostate cancer according to the present invention comprises reacting a PSA contained in a sample composed of urine collected from a human body which is suspected to be suffering from prostate cancer with (1) a fucose ?1?6 affinitive lectin which has a characteristic property that the lectin has affinity expressed by a binding constant of 1.0×104 M?1 or more (at 25° C.) for an ?1?6 fucose sugar chain No. 405. The fucose ?1?6 affinitive lectin is preferably (2) a fucose ?1?6 specific lectin which has a characteristic property that the lectin has a binding constant of 1.0×104 M?1 or less (at 25° C.) for a sugar chain No. 003 that does not contain ?1?6 fucose and a glycolipid-type sugar chain No. 909 that does not contain ?1?6 fucose.Type: GrantFiled: February 3, 2017Date of Patent: January 18, 2022Assignees: J-CHEMICAL, INC., OSAKA UNIVERSITYInventors: Yuka Kobayashi, Kazutoshi Fujita, Norio Nonomura, Eiji Miyoshi
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Patent number: 11227759Abstract: An electrostatic linear ion trap (ELIT) array includes multiple elongated charge detection cylinders arranged end-to-end and each defining an axial passageway extending centrally therethrough, a plurality of ion mirror structures each defining a pair of axially aligned cavities and an axial passageway extending centrally therethrough, wherein a different ion mirror structure is disposed between opposing ends of each cylinder, and front and rear ion mirrors each defining at least one cavity and an axial passageway extending centrally therethrough, the front ion mirror positioned at one end of the arrangement of charge detection cylinders and the rear ion mirror positioned at an opposite end of the arrangement of charge detection cylinders, wherein the axial passageways of the charge detection cylinders, the ion mirror structures, the front ion mirror and the rear ion mirror are coaxial to define a longitudinal axis passing centrally through the ELIT array.Type: GrantFiled: January 11, 2019Date of Patent: January 18, 2022Assignee: The Trustees of Indiana UniversityInventors: Martin F. Jarrold, Daniel Botamanenko