Patents Assigned to University
  • Patent number: 12286609
    Abstract: The invention provides a skin culturing apparatus configured for biphasic culturing of mammalian skin and/or a mammalian skin substitute. The apparatus comprises a first chamber that is configured to provide a gaseous environment having a relative humidity below 90% and comprising less than 5% CO2, and a second chamber that is configured to provide tissue culture medium at a temperature of 33.0-37.5° C. and pH of 6.1-7.9. The invention also provides methods for culturing mammalian skin and/or skin substitutes, as well as methods for testing mammalian skin and/or mammalian skin substitutes cultured in the skin culturing apparatus.
    Type: Grant
    Filed: October 16, 2019
    Date of Patent: April 29, 2025
    Assignee: QUEEN MARY UNIVERSITY OF LONDON
    Inventors: Rosalind Francesca Hannen, Jose Rafael Castrejón-Pita
  • Patent number: 12286983
    Abstract: A corrugated diaphragm actuator may include a chamber body including a plurality of walls defining a cavity. The plurality of walls may include a first wall including a first corrugated diaphragm defining at least one first corrugated channel, and the corrugated diaphragm may be configured for expanding outwardly when a positive pressure is applied within the cavity.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: April 29, 2025
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Muthu Wijesundara, Veysel Erel
  • Patent number: 12289126
    Abstract: A method and a device for joint suppression of narrowband and multiple access interference are provided. The method includes: performing time domain windowing processing on a received signal, and performing frequency domain interference processing on a signal after windowing processing to obtain a matched filter and a time domain signal; obtaining reconstructed baseband received data for a signal of each channel; obtaining reconstructed signals after matched filtering; accumulating the reconstructed signals of multiple channels to obtain a reconstructed accumulated value, obtaining a compensation value according to a difference between the time domain signal and the reconstructed accumulated value, and compensating the reconstructed signals with the compensation value to obtain an actual received signal of the each channel; and outputting a joint suppression result.
    Type: Grant
    Filed: December 17, 2024
    Date of Patent: April 29, 2025
    Assignee: NATIONAL UNIVERSITY OF DEFENSE TECHNOLOGY
    Inventors: Jingyuan Li, Rong Zhou, Xinming Huang, Shaojie Ni, Hang Gong, Wenxiang Liu, Zengjun Liu, Ke Zhang, Yuchen Xie, Sixin Wang, Kuo Cao
  • Patent number: 12285273
    Abstract: Knee joint laxity testing apparatus configured to measure knee laxity in three planes of motion includes a foot and ankle stabilization assembly including a foot plate, a heel clamp and a tibial clamp for securing a foot and an ankle of a person, an anterior-posterior (AP) loading assembly configured to apply an anterior/posterior loading on a knee of the person, and a thigh stabilization assembly including a proximal thigh fixation module and a distal thigh fixation module. The proximal thigh fixation module includes a thigh cradle and a pair of clamping arms for securing a thigh positioned on the thigh cradle. Each clamping arm is pivotable about a hinge. The distal thigh fixation module is operable to firmly hold a distal portion of a thigh of the person in place while a leg of the person is manipulated.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: April 29, 2025
    Assignee: University of North Carolina at Greensboro
    Inventors: Sandra Janine Shultz, Randy Joe Schmitz, James Avery Coppock, Sam Seyedin
  • Patent number: 12285793
    Abstract: A forming device and a forming method for a part with a regular cross-section are provided, and relates to the technical field of metal member forming and manufacturing. A part to be formed is heated by a part heating temperature control assembly to obtain required microstructure evolution, so that the forming performance is improved. A temperature control die assembly can be heated by setting die heating assemblies, so that hot stamping, die quenching and stress relaxation can be carried out. The internal stress state of the part is controlled by an axial force control assembly.
    Type: Grant
    Filed: March 31, 2024
    Date of Patent: April 29, 2025
    Assignees: DALIAN UNIVERSITY OF TECHNOLOGY, AVIC MANUFACTURING TECHNOLOGY INSTITUTE
    Inventors: Kailun Zheng, Dechong Li, Lihua Du, Yujie Han
  • Patent number: 12288135
    Abstract: Techniques for performing quantum information processing using an asymmetric error channel are provided. According to some aspects, a quantum information processing includes a data qubit and an ancilla qubit, the ancilla qubit having an asymmetric error channel. The data qubit is coupled to the ancilla qubit. The ancilla qubit may be driven with a stabilizing microwave field to create the asymmetric error channel.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: April 29, 2025
    Assignee: Yale University
    Inventors: Shruti Puri, Alexander Grimm, Philippe Campagne-Lbarcq, Steven M. Girvin, Michel Devoret
  • Patent number: 12288994
    Abstract: In one example, an active variable reactance rectifier circuit includes an active variable reactance rectifier circuit input port and an output port. A power splitter circuit includes an input port coupled to the active variable reactance rectifier circuit input port and a pair of output ports. A first rectifier circuit includes an input port is coupled to the first power splitter circuit output port. A second rectifier circuit includes an input port coupled to the second power splitter circuit output port. A power combiner circuit includes a first input port, a second input port and an output port. The first power combiner circuit input port is coupled to the first rectifier circuit output port, the second power combiner circuit input port is coupled to the second rectifier circuit output port and the power combiner circuit output port is coupled to the active variable reactance rectifier circuit output port.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: April 29, 2025
    Assignee: The Regents of the University of Colorado, a body corporate
    Inventors: Khurram K. Afridi, Ashish Kumar, Sreyam Sinha
  • Patent number: 12285418
    Abstract: Three compounds having a common molecular template of 2-(5-(N-acylamino)pyridin-2-yl)-N-benzylacetamide (Compounds I, II and I) are identified as potential anticancer therapeutic agents, and for the treatment of Acute Myeloid Leukemia (AML) in particular. Compound I was specifically designed to target AML cells, inhibit growth, and induce cell death. Compound I demonstrated a dose-dependent effect on AML cell lines HL-60, Mv4-11, KG-1a, and K562.
    Type: Grant
    Filed: August 29, 2024
    Date of Patent: April 29, 2025
    Assignees: University of Jeddah, King Abdulaziz University
    Inventors: Roaa M. Alreemi, Hind A. Alkhatabi, Abdelsattar M. Omar, Mohammed A. Baradwan, Yosra A. Muhammad, Peter Natesan Pushparaj, Mohammad Basabrain, Moustafa E. El-Araby
  • Patent number: 12286650
    Abstract: The purpose of the present invention is to provide a set of two polypeptides for use in light-dependent genetic recombination in which the N-terminal side fragment and the C-terminal side fragment of a Cre protein having an amino acid sequence of SEQ ID NO: 1 respectively bind to two proteins light-dependently forming a dimer.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: April 29, 2025
    Assignee: The University of Tokyo
    Inventor: Moritoshi Sato
  • Patent number: 12286633
    Abstract: Compositions and methods for modifying genomic DNA sequences of a plant cell are provided. The methods produce double stranded breaks at target sites in a genomic DNA sequence, resulting in mutation, insertion, and/or deletion of DNA sequences at the target site(s) in a genome. The compositions comprise DNA constructs comprising nucleotide sequences that encode a Cas12b protein. The DNA constructs can be used to direct the modification of genomic DNA at a target site. Methods to use these DNA constructs to modify genomic DNA sequences are described herein. Additionally, compositions and methods for modulating the expression of genes are provided.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: April 29, 2025
    Assignee: University of Maryland, College Park
    Inventor: Yiping Qi
  • Patent number: 12285918
    Abstract: The present invention relates to a printing device and a printing method. The combination mode between materials in an additive manufacturing process is improved. A calculation unit is used for controlling an A pole unit and a B pole unit to be in contact with the materials, to form an energized circuit. The surface temperature of phase change material in the material between the A pole unit and the B pole unit is greater than or equal to a preset temperature so that the materials at a distance can be simultaneously combined.
    Type: Grant
    Filed: April 13, 2023
    Date of Patent: April 29, 2025
    Assignee: Qingdao University of Science and Technology
    Inventors: Yan He, Dianming Chu, Wenjuan Bai
  • Patent number: 12287287
    Abstract: In one aspect, there is provided a system including at least one processor, and at least one memory including program code which when executed by the at least one processor causes operations including capturing an image of at least a portion of a surface of an object; generating, from the captured image, pixel intensity data; in response to generating the pixel intensity data, determining, based on a height error model, height error data, wherein the height error data indicates an uncertainty of at least one height measurement of the object; and determining, based on the height error data, whether the object satisfies a threshold criteria for acceptance of the object. Related system, methods, and articles of manufacture are also disclosed.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: April 29, 2025
    Assignee: The Regents Of the University of California
    Inventors: Niall O'Dowd, Michael Todd
  • Patent number: 12288015
    Abstract: A method of designing an internal structure of a foamed resin sound absorbing material includes: setting a microscopic structure model with a structure equivalent to the internal structure of the foamed resin sound absorbing material; calculating an acoustic characteristic by homogenization for each of a plurality of microscopic structure models, each being the microscopic structure model; identifying a relational expression between a Biot's parameter of the foamed resin sound absorbing material and the microscopic structure model; setting a target acoustic characteristic; identifying a Biot's parameter for achieving the target acoustic characteristic set, by Biot's modeling; and identifying a microscopic structure model corresponding to the Biot's parameter identified.
    Type: Grant
    Filed: September 21, 2021
    Date of Patent: April 29, 2025
    Assignees: MAZDA MOTOR CORPORATION, KOGAKUIN UNIVERSITY
    Inventors: Daiji Katsura, Keisuke Yamakawa, Takashi Yamamoto
  • Patent number: 12288499
    Abstract: The present invention includes systems and methods for a six-primary color system for display. A six-primary color system increases the number of primary colors available in a color system and color system equipment. Increasing the number of primary colors reduces metameric errors from viewer to viewer. The six-primary color system includes Red, Green, Blue, Cyan, Yellow, and Magenta primaries. The systems of the present invention maintain compatibility with existing color systems and equipment and provide systems for backwards compatibility with older color systems.
    Type: Grant
    Filed: April 4, 2024
    Date of Patent: April 29, 2025
    Assignee: Baylor University
    Inventors: James M. DeFilippis, Gary B. Mandle
  • Patent number: 12285467
    Abstract: Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and/or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.
    Type: Grant
    Filed: November 3, 2020
    Date of Patent: April 29, 2025
    Assignee: The Rockfeller University
    Inventors: David Bikard, Luciano Marraffini
  • Patent number: 12287352
    Abstract: A motion sensing system uses high-voltage biasing to achieve high resolution with ultra-low power. The motion sensing system consists of a motion sensor, a readout circuit, and a high-voltage bias circuit to generate the optimized bias voltage for the motion sensor. By using the high-voltage bias, the signal from the motion sensor is raised above the readout circuit's noise floor, eliminating the power-hungry amplifier and signal-chopping used in conventional motion sensing systems. The bias circuit, while producing the programmable bias voltages for the motion sensor, also compensates for the process mismatch raised by the high voltage biases.
    Type: Grant
    Filed: November 9, 2022
    Date of Patent: April 29, 2025
    Assignee: The Regents of The University of Michigan
    Inventors: Yimai Peng, David Blaauw, Dennis Sylvester, David Kyojin Choo
  • Patent number: 12287360
    Abstract: The present invention discloses a GaN HEMT device for irradiation damage detection which comprises a substrate layer, a gallium nitride layer, a barrier layer and a dielectric layer. A p-type gallium nitride layer is provided on the barrier layer. A drain and a source are respectively located at an inner side and an outer side of the p-type gallium nitride layer and provided on the gallium nitride layer. A Schottky metal layer is provided on the p-type gallium nitride layer. A first ohmic metal layer and a second ohmic metal layer are respectively located at an inner side and an outer side of the p-type gallium nitride layer and provided on the barrier layer. The second ohmic metal layer includes inner gear electrodes and outer gear electrodes, which are interdigital with each other.
    Type: Grant
    Filed: December 30, 2024
    Date of Patent: April 29, 2025
    Assignee: NANJING UNIVERSITY
    Inventors: Feng Zhou, Can Zou, Hai Lu, Weizong Xu, Dong Zhou, Fangfang Ren
  • Patent number: 12287393
    Abstract: In various example embodiments, a system and method for tracking objects in a three-dimensional space is disclosed. One method includes receiving detections representing targets, increasing a classification of a track in response to a detection matching the track, decreasing a classification of a track in response to no detections matching the track, and processing detections according to a classification level of the track.
    Type: Grant
    Filed: June 9, 2021
    Date of Patent: April 29, 2025
    Assignee: Utah State University Space Dynamics Laboratory
    Inventors: Morgan Davidson, Jacob Christensen
  • Publication number: 20250133304
    Abstract: This application provides an event data processing method, including: obtaining event data shot by an event camera, where the event data includes a timestamp of occurrence of an event, pixel coordinates, and a brightness change status; and generating an event frame matrix based on a plurality of pieces of event data within a preset time period, where a location of a matrix element in the event frame matrix corresponds to pixel coordinates, a value of the matrix element indicates whether there is an event at a corresponding pixel and an event polarity of a pixel with an event, if there is an event at the pixel, it indicates that brightness of the pixel is changed within the preset time period, or if there is no event at the pixel, it indicates that brightness of the pixel is not changed, and the event polarity includes increased brightness and decreased brightness.
    Type: Application
    Filed: December 30, 2024
    Publication date: April 24, 2025
    Applicants: TSINGHUA UNIVERSITY, HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Yaoyuan Wang, Mingsheng Long, Kaichao You, Ziyang Zhang, Ying Wang, Yunlong Zhan, Jianmin Wang
  • Publication number: 20250130299
    Abstract: A method of quantifying sodium concentration can include extracting one or more bi-T2 sodium signals from one or more echo time acquisitions. The method can include separating, via a matrix equation including at least one of T2 decays or T2* decays of mono-T2 sodium and bi-T2 sodium, an intensity of the one or more bi-T2 sodium signals from an intensity of one or more mono-T2 sodium signals. The method can include quantifying bi-T2 sodium concentration, mono-T2 sodium concentration, and total sodium concentration based on the one or more echo time acquisitions. The one or more echo time acquisitions can be performed with single-quantum sodium excitations.
    Type: Application
    Filed: October 18, 2024
    Publication date: April 24, 2025
    Applicant: New York University
    Inventors: Yongxian Qian, Fernando E. Boada