Abstract: An intraocular lens (IOL) has a small, central lens suspended within a pliable housing and, when the housing is filled with liquid, is coaxially aligned with a second small lens embedded in the wall of the housing. The suspension is on a dome- or other-shaped webbing attached to an inner circumference of the wall. When filled with liquid, forces squeezing or pulling the equator of the housing, as with ciliary muscles in the eye, adjust a distance between the lenses in order to adjust focus. Optional haptics may project from points on or above and below the equator. A recess in the posterior hemisphere of the housing can keep cell growth away from an optical axis of the lens system. A third small lens can be embedded in an opposite wall of the housing and coaxially aligned with the other lenses to form a three-lens, ultra-zoom system.

Abstract: A gripper mechanism is provided, which relates to the technical field of grippers. The gripper mechanism includes a motor, a cylinder barrel, a piston and a guide assembly. The piston reciprocates in the cylinder barrel under the action of the motor and the guide assembly. The piston includes a piston body and a piston rod located in the piston body. Both ends of the cylinder barrel are respectively provided with cylinder heads for limiting the maximum distance and the minimum distance between the piston body and a part to be gripped. The piston rod includes a driving shaft, a cross slider coupling and a gripping head which are connected in turn. The power output by the motor is transmitted to the gripping head through the driving shaft and the cross slider coupling in turn.

Abstract: Provided is a manufacturing method of a Van der Waals contact semiconductor device, which includes arranging and patterning a first material on a first substrate; arranging and patterning a second material on a second substrate; and transferring the second material onto the first material, in which any one of the first material and the second material is a topological insulator (TI), and the other one includes a two-dimensional semiconductor material, and the first material and the second material are subjected to Van der Waals contact.

Abstract: Embodiments described herein provide for a healthcare ecosystem of computing devices participating as nodes of a distributed ledger (e.g., blockchain). The distributed ledger includes NFTs representing corresponding patients, where the initial NET behaves logically as a token scaffold that represents a “digital twin” of the particular patient. The initial patient token represents personal profile data of patient personal data for the patient. The nodes may generate new data and/or new sub-tokens (or other blockchain entry type) representing new data, which the nodes associate with the token scaffold. The sub-tokens contain data for representing physical or digital specimens, health data, and data derived from the health data (e.g., cell lines, organoids, other model systems).

Abstract: A method for forming a memory device is provided. The method includes forming first and second metal-insulator-semiconductor (MIS) structures, wherein each of the first and second MIS structures comprises a semiconductor layer, an insulating layer over the semiconductor layer, and a metal electrode layer over the insulating layer; performing a first breakdown process to the first MIS structure; performing a second breakdown process to the second MIS structure; performing a first read operation by supplying a reading voltage pulse to the metal electrode layer of the first MIS structure and detecting a first read current flowing through the first MIS structure; and performing a second read operation by supplying the reading voltage pulse to the metal electrode layer of the second MIS structure and detecting a second read current flowing through the second MIS structure, wherein the second read current is greater than the first read current.

Abstract: System for effecting a reversible sensory block includes a hybrid neuromodulator and hybrid lead for delivering electrical and pharmacological stimulation. An implantable modulator provides electrical pulse generation and pharmacological fluid infusion. Method for effecting a reversible sensory block delivers low-frequency stimulation based on the conduction velocity of a target afferent. Afferents with different conduction velocities may be blocked by stimulation with different frequencies. Temporally synchronized pulse stimuli from multiple stimulating electrodes may interfere with each other to stimulate a specific afferent. Spatial summation of synchronized low-frequency pulse stimulation may be delivered at multi-sites. Temporal interference of two kilohertz sinusoidal stimuli with slight frequency difference deliver a low-frequency sinusoidal stimulus at a focal region of interference. Spatial summation translates to evoked action potentials that converge at T-junction of a targeted afferent.

Abstract: Compositions and process, along with systems using those compositions and processes are described herein for remediation of environmental contamination, including organic compound contamination of soil and ground water, including polyfluoroalkyl substances.

Abstract: The disclosure provides a construction method including steps of: constructing a detailed model and a simplified model of the rail vehicle using finite element method based on the three-dimensional structure of the rail vehicle; initially setting the simplified model in accordance with the detailed model, including specifying materials, mechanical properties parameters, and mass point; setting different simplification thickness ratio to obtain a plurality of sets of the simplified models, designing longitudinal and lateral collision conditions, and in each type of the collision conditions, performing collision simulations on the detailed model and each set of the simplified models under each thickness ratio to obtain respective collision response curves; calculating a total CORA value corresponding to the plurality of sets of the simplified models; selecting an optimal simplified model from n sets of the simplified models with the highest total CORA values.

Abstract: A method of making an electrocatalyst, including dissolving a copper salt and an aromatic compound in a solvent to form a first mixture, heating the first mixture to a temperature of 90-120° C. for 1-20 hours (h) to form a copper complex, heating the copper complex under a nitrogen atmosphere at a temperature of 500-1,000° C. to form a nanocomposite; and coating a layer of the nanocomposite on a substrate to form the electrocatalyst. The nanocomposite contains copper nanoparticles (NPs) and nitrogen-doped carbon nanosheets. The copper NPs are uniformly dispersed on a surface of the nitrogen-doped carbon nanosheets, the nitrogen-doped carbon nanosheets have an average thickness of 0.1-10 nm, and the copper NPs are spherical and have an average diameter of 2-10 nm.

Abstract: An application of Bone Marrow Mesenchyml Stem Cell Exosomes (BMSC-Exos) in treating Parkinson's disease (PD) is provided, wherein the BMSC-Exos are generated by stimulating BMSCs with a culture solution and extracted from the culture solution after passage; and the culture solution of the BMSCs is an ?-MEM culture solution containing FBS and PS. The BMSC-Exos can greatly improve a motor function of a model mouse with PD, protect dopaminergic neurons of the model mouse with PD, improve an olfactory function of the model mouse with PD, and also inhibit the activation of olfactory astrocytes of the model mouse with PD.

Abstract: Systems and methods are described herein that create discrete volumes associated with solid-phase particles (e.g., drop-carrier particles) suspended in an immiscible phase (e.g., dropicles). One embodiment of the system includes a plurality of hydrogel-based drop-carrier particles containing a microscale voids or cavities that hold an aqueous phase droplet of fluid within each drop-carrier particle. The plurality of hydrogel drop-carrier particles associated with aqueous drops are suspended as individual elements in an immiscible oil phase. The microscale hydrogel drop-carrier particles containing the voids or cavities may be manufactured using microfluidic droplet generators. The dropicles may be used to analyze single-entities (e.g., single-molecules and single-cells) and analytes.

Abstract: The present disclosure relates to a highly thermally conductive composite material in which PITCH-based carbon fiber is stitched into a prepreg laminate in which a prepreg including carbon fiber and a thermosetting resin is laminated, and a method for manufacturing the same, and the highly thermally conductive composite material may have excellent through-thickness thermal conductivity, in-plane thermal conductivity and strength.

Abstract: Disclosed is an optimization method for resource allocation in a perception-enhanced cognitive radio network based on an IRS (intelligent reflecting surface).

Abstract: An object of the present invention is to provide a method for producing T cells or NK cells, a culture medium for culturing T cells or NK cells, a method for culturing T cells or NK cells, a method for maintaining the undifferentiated state of undifferentiated T cells, and a growth promoter for T cells or NK cells, which are capable of efficiently proliferating T cells or NK cells and maintaining the state of the cells (for example, undifferentiated property). The present invention relates to a method for producing T cells or NK cells including culturing T cells or NK cells in a culture medium containing a bisbenzylisoquinoline alkaloid represented by formula (X-1) or formula (X-2) or a compound resulting from cleavage of one ether bond thereof or a pharmaceutically acceptable salt thereof, and the like.

Abstract: Materials are disclosed that superconduct at high temperatures and low pressures. Methods of making and measuring the materials are also disclosed. In a particular embodiment, a nitrogen-doped (or other lightweight-atom doped) rare earth metal hydride is disclosed. Also disclosed are thermodynamic pathways to recovering materials that superconduct at room temperature and room pressure and/or at other desirable operating temperatures and pressures to enable superconductivity at conditions that make a wider range of superconductive applications practical. These and other aspects of various embodiments are disclosed herein.

Abstract: The present invention relates to a silicon composite anode material with controlled particle size distribution, a manufacturing method thereof, and a lithium-ion battery containing the same. More specifically, the present invention relates to a silicon composite anode material with controlled particle size distribution, which exhibits stress relaxation of each particle through distribution of various particle sizes and thus prevents mechanical destruction even under a high-pressure condition during a calendering process, a manufacturing method thereof, and a lithium-ion battery containing the same. The silicon composite anode material comprises a graphite mixture; a silicon nanolayer coated on the graphite mixture; and a carbon coating layer coated on the silicon nanolayer.

Abstract: An antenna assembly may include a shape change antenna configured to transmit an electromagnetic wave or receive an electromagnetic wave. The shape change antenna may have an antenna shape and may be formed of a conductive shape memory material that physically moves in response to changes in a non-geometric characteristic. The antenna assembly may also include a shape change stimulator configured to change the non-geometric characteristic of the shape change antenna to cause the antenna shape to physically change between a first geometry and a second geometry.

Abstract: A device for decoding a feature map according to the present disclosure comprises an image decoding unit to decode an image from a bitstream; an inverse format conversion unit to restore a feature map latent representation by converting a formation of a decoded image; and a feature map restoration unit to restore a multi-layer feature map from the feature map latent representation. Here, the feature map restoration unit restores the multi-layer feature map based on a learned neural network parameter.

Abstract: Provided is a driving device for detecting mechanical characteristics and electrical characteristics of cells. A structure of the driving device includes a piezoelectric stack, a bridge-type flexible hinge mechanism, a parallel hinge mechanism, a lead screw guide rail, a stepping motor, a linear displacement sensor, a force sensor, a ceramic needle, a first electrode, a second electrode, a cell container, an XY axis displacement platform, a positioning hole, a first metal base, a second metal base, a first metal connecting plate, a second metal connecting plate, a first pre-tightening wedge, a second pre-tightening wedge, screws, and a pre-tightening screw. During the operation of the driving device, the piezoelectric stack is driven under an excitation effect of a driving electric field signal, such that the bridge-type flexible hinge mechanism stretches, and the ceramic needle is driven by the parallel flexible hinge mechanism to move downwards.

Abstract: A device and method for detecting the presence of, or measuring the concentration or amount of, at least one large analyte in a sample fluid. The device has at least one electrode, a sample fluid and a plurality of aptamers capable of binding to the analyte. The aptamers are physically bound to the device. In addition, the aptamers each include at least one redox tag and also, the aptamers have two or more binding portions that bind to two or more distinct binding sites on the analyte in the sample fluid.