Abstract: The present invention provides methods of treating cancer with certain co-activator of activator protein-1 and estrogen receptor (CAPER)-based polypeptides. In certain embodiments, the methods of the invention target only cancerous cells without adversely affecting non-cancerous cells.

Abstract: Provided are methods for sequential radiotherapies, such as XRT. In some embodiments, a higher dosage of an XRT may first be administered to a subject, optionally in combination with an immunotherapy, and subsequently a lower dosage XRT is administered to the subject to treat a cancer. Separating the dosage and intensity of the radiotherapies can be used to achieve improved therapeutic responses, such as improved anti-cancer responses, survival times, and/or abscopal effects.

Abstract: The present disclosure relates to the detection of analytes in high volumetric flow applications. Particular embodiments relate to the use of fluorescence polarization/anisotropy based for detection of analytes in a flow cell. In one testing format, an analyte of interest is probed with reagents containing fluorescent labeled recognition elements. When present in a sample or portion of a sample, thee labeled analyte produces a shift in fluorescence polarization/anisotropy/intensity/lifetime as the output signal following the binding of the recognition elements to the analytes.

Abstract: Provided is a water-insoluble crosslinked structure with an excellent metal-adsorbing effect. The crosslinked structure is formed by crosslinking a first linear polymer and a second linear polymer. The first linear polymer has a plurality of pendant groups represented by Formula (a). The second linear polymer has a plurality of pendant groups represented by Formula (a). Some of the plurality of pendant groups in the first linear polymer and some of the plurality of pendant groups in the second linear polymer are bonded to each other via a crosslinker. In the formula, ring Z represents a heterocycle containing a nitrogen atom as a heteroatom, R1 represents a single bond or an alkylene group having from 1 to 10 carbons, and Q+ represents a counter cation.

Abstract: An optical architecture for enhancing phase modulation depth for a phase light modulator includes a laser light source, a 4f, 1:1 relay where a tilted mirror with a center hole is placed at the backfocal point of the first lens. A vertically polarized (VP) and collimated light is deflected by a polarized beam splitter (PBS), followed by passing through a Quarter Wave Plate (QWP) that converts linear polarization (LP) to right circular polarization (RCP). Upon interaction of the RCP light with PLM, spatial phase is modulated by 2kd(i,j). PLM reflects and modulates phase of light while changing the handness of polarization from RHP to left hand circular polarization (LCP). The 2nd interaction with QWP changes polarization of light from LCP to horizontally polarized (HP) light. The mirror M1 is placed at a half of the Talbot distance from the PLM as described later. The reflected light by M1 is a HP light, therefore it goes through the PBS and is converted to RCP by the 3rd interaction with QWP.

Abstract: An object of the present invention is to provide a method for producing T cells or NK cells, a culture medium for culturing T cells or NK cells, a method for culturing T cells or NK cells, a method for maintaining the undifferentiated state of undifferentiated T cells, and a growth promoter for T cells or NK cells, which are capable of efficiently proliferating T cells or NK cells and maintaining the state of the cells (for example, undifferentiated property). The present invention relates to a method for producing T cells or NK cells including culturing T cells or NK cells in a culture medium containing a bisbenzylisoquinoline alkaloid represented by formula (X-1) or formula (X-2) or a compound resulting from cleavage of one ether bond thereof or a pharmaceutically acceptable salt thereof, and the like.

Abstract: Materials are disclosed that superconduct at high temperatures and low pressures. Methods of making and measuring the materials are also disclosed. In a particular embodiment, a nitrogen-doped (or other lightweight-atom doped) rare earth metal hydride is disclosed. Also disclosed are thermodynamic pathways to recovering materials that superconduct at room temperature and room pressure and/or at other desirable operating temperatures and pressures to enable superconductivity at conditions that make a wider range of superconductive applications practical. These and other aspects of various embodiments are disclosed herein.

Abstract: The present invention relates to a silicon composite anode material with controlled particle size distribution, a manufacturing method thereof, and a lithium-ion battery containing the same. More specifically, the present invention relates to a silicon composite anode material with controlled particle size distribution, which exhibits stress relaxation of each particle through distribution of various particle sizes and thus prevents mechanical destruction even under a high-pressure condition during a calendering process, a manufacturing method thereof, and a lithium-ion battery containing the same. The silicon composite anode material comprises a graphite mixture; a silicon nanolayer coated on the graphite mixture; and a carbon coating layer coated on the silicon nanolayer.

Abstract: An antenna assembly may include a shape change antenna configured to transmit an electromagnetic wave or receive an electromagnetic wave. The shape change antenna may have an antenna shape and may be formed of a conductive shape memory material that physically moves in response to changes in a non-geometric characteristic. The antenna assembly may also include a shape change stimulator configured to change the non-geometric characteristic of the shape change antenna to cause the antenna shape to physically change between a first geometry and a second geometry.

Abstract: A device for decoding a feature map according to the present disclosure comprises an image decoding unit to decode an image from a bitstream; an inverse format conversion unit to restore a feature map latent representation by converting a formation of a decoded image; and a feature map restoration unit to restore a multi-layer feature map from the feature map latent representation. Here, the feature map restoration unit restores the multi-layer feature map based on a learned neural network parameter.

Abstract: An image encoding/decoding method and apparatus and a method for transmitting a bitstream generated by the image encoding method are provided. The image encoding method according to the present disclosure may include: encoding an image in sub-regions with different sizes and generating one or more bitstreams for the sub-regions; obtaining a user viewport for the image; allocating sub-regions corresponding to the user viewport among the sub-regions to the image, wherein the image includes an inner region located inside the user viewport, a boundary region adjacent to a boundary of the user viewport, and an outer region located outside the user viewport; and generating at least one bitstream corresponding to the allocated sub-regions from bitstreams for the sub-regions, and a sub-region with a relatively large size may be allocated within the inner region, and a sub-region with a relatively small size may be allocated within the boundary region.

Abstract: A method of detecting SARS-CoV includes amplifying isothermally a target sequence in a sample with at least one set of oligonucleotide primers and assaying the sample with a SARS assay to detect the target sequence of a SARS-CoV nucleic acid sequence. A kit for detecting SARS-CoV in a sample includes a reverse transcriptase, a universal primer set suitable for loop-mediated isothermal amplification (LAMP) of the target sequence in a SARS-CoV nucleic acid sequence and variants thereof containing mutations within one or more primer binding sites.

Abstract: Methods for treating a peripheral neuropathy are disclosed herein. Methods are also disclosed for improving nerve function in a subject with a peripheral neuropathy. These methods use a PNPase inhibitor or a PNPase purine nucleoside substrate. These methods include selecting the subject with the peripheral neuropathy; and administering to the subject a therapeutically effective amount of a purine nucleoside phosphorylase (PNPase) inhibitor and/or a PNPase purine nucleoside substrate.

Abstract: Provided is an agent for improving intestinal bacteria that contains a proteolytic enzyme-decomposed residue of a soybean protein material and inhibits the growth of opportunistic bacteria.

Abstract: The present disclosure discloses a computing-aware traffic steering method, apparatus and system in a mobile network. According to the present disclosure, there is provided a computing-aware traffic steering method of mobile network control plane, the method including: in a case where it is confirmed that there is no target data network access identifier (DNAI) mapped to a service ID when a PDU session establishment request including the service ID of a user terminal (UE) is made, transmitting the service ID and user plane path information to a computing-aware traffic steering mobile user plane controller (CATS-MUP-C) using segment routing; reconfiguring a user plane path for accessing an Anycast IP address corresponding to the service ID in conjunction with the CATS-MUP-C; and completing the PDU session establishment using the Anycast IP address.

Abstract: Certain examples of the disclosure concern an implantable sensor. The implantable sensor includes a sensor assembly configured to connect to a suture. The sensor assembly also includes a substrate and a resonant circuit coupled to the substrate. The resonant circuit is configured to electrically resonate at a resonant frequency when exposed to a first electromagnetic field and to emit a second remotely detectable electromagnetic field. The substrate is configured to deform in response to a tensile force applied by the suture and to change a resonant parameter of the resonant circuit in response to the deformation.

Abstract: A compound represented by formula [I]: wherein R12, R13, R14, R15, and R16 are the same or different and are each hydrogen, halogen, C1-6 alkyl optionally substituted with halogen, or C1-6 alkoxy optionally substituted with halogen; R21, R22, and R23 are the same or different and are each hydrogen, halogen, C1-6 alkyl optionally substituted with halogen, C1-6 alkoxy optionally substituted with halogen, sulfanyl optionally substituted with halogen, nitro, or cyano; R3 is C1-6 alkyl or the like; and X? is an anion.

Abstract: The present disclosure is directed to dual specificity antibodies which may bind to PD-L1 or PD-L2 and methods of using such antibodies to treat cancers, such as those that express or overexpress PD-L1 or PD-L2.

Abstract: The present disclosure provides a pyrolysis process for converting an additive-containing plastic comprising a polyolefin polymer to an alkene, an alkane, or a mixture thereof. The process comprises contacting the plastic with a catalyst in a one-pot pyrolysis system at a temperature between about 350° C. and about 500° C.; wherein the catalyst comprises a solid acid selected from the group consisting of HY, HZSM-5, and Al-SBA-15. The present disclosure further provides a one-pot pyrolysis system and uses of a solid acid in the pyrolysis process for converting plastic comprising a polyolefin polymer to an alkene.

Abstract: The present disclosure provides methods for sorting retinal cells for use in cellular component transfer therapy, sorted populations of retinal cells generated by such methods, and compositions comprising such sorted populations of retinal cells. The present disclosure also provides uses of sorted populations of retinal s and compositions comprising thereof for preventing and/or treating inherited retinal degenerative diseases.