Abstract: Polyester compositions and functionalized polyester compositions are provided along with methods of making the compositions as well as methods of using the compositions, for example as a tissue engineering bioscaffold and as a drug-delivery vehicle.
Type:
Grant
Filed:
January 25, 2011
Date of Patent:
May 5, 2015
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education
Abstract: Methods involve a combination of polyelectrolyte multilayer (PEM) coating or silane self assembly on a substrate; microcontact printing; and conductive graphite particles, especially size controlled highly conductive exfoliated graphite nanoplatelets. The conductive graphite particles are coated with a charged polymer such as sulfonated polystyrene. The graphite particles are patterned using microcontact printing and intact pattern transfer on a substrate that has an oppositely-charged surface. The method allows for conductive organic patterning on both flat and curved surfaces and can be used in microelectronic device fabrication.
Type:
Grant
Filed:
September 14, 2012
Date of Patent:
May 5, 2015
Assignee:
Board of Trustees of Michigan State University
Inventors:
Ilsoon Lee, Lawrence T. Drzal, Jue Lu, Troy R. Hendricks
Abstract: The disclosure relates to a system, and a method, for automatically selecting a personal media apparatus and managing data under a smart media cloud environment. Specifically, the system, and the method, for automatically selecting a personal media apparatus and managing data under a smart media cloud environment, provide functions of determining the degree of control of a device and the automatic conversion of media service between a smart media contents and a cloud media contents under a private network environment by automatically selecting and controlling, in accordance with a media contents, a variety of output device under UPnP and DLNA environments, and under the structure of converting a cloud media streaming data with a media renderer connected in a smart device.
Type:
Grant
Filed:
December 27, 2011
Date of Patent:
May 5, 2015
Assignee:
Konkuk University Industrial Cooperation Corp.
Inventors:
Han-ku Lee, Hyo-Gun Yoon, Myoung-Jin Kim, Yun Cui
Abstract: The present invention encompasses compositions and methods for effectively treating at least one symptom or sign of methamphetamine use, or for slowing the rate of (+) methamphetamine entry into the brain of a subject. The method comprises administering an effective amount of an anti-(+) methamphetamine antibody to a subject.
Type:
Grant
Filed:
March 13, 2013
Date of Patent:
May 5, 2015
Assignee:
The Board of Trustees of the University of Arkansas
Inventors:
Samuel Michael Owens, Ralph Henry, Alicia Brown
Abstract: This disclosure provides systems, methods, and apparatus related to field-effect p-n junctions. In one aspect, a device includes an ohmic contact, a semiconductor layer disposed on the ohmic contact, at least one rectifying contact disposed on the semiconductor layer, a gate including a layer disposed on the at least one rectifying contact and the semiconductor layer and a gate contact disposed on the layer. A lateral width of the rectifying contact is less than a semiconductor depletion width of the semiconductor layer. The gate contact is electrically connected to the ohmic contact to create a self-gating feedback loop that is configured to maintain a gate electric field of the gate.
Type:
Grant
Filed:
February 22, 2013
Date of Patent:
May 5, 2015
Assignee:
The Regents of the University of California
Abstract: An epitaxial structure is provided. The epitaxial structure includes a substrate, an epitaxial layer and a carbon nanotube layer. The epitaxial layer is located on the substrate. The carbon nanotube layer is located between the substrate and the epitaxial layer. The carbon nanotube layer can be a carbon nanotube film drawn from a carbon nanotube array and including a plurality of successive and oriented carbon nanotubes joined end-to-end by van der Waals attractive force therebetween.
Type:
Grant
Filed:
October 14, 2011
Date of Patent:
May 5, 2015
Assignees:
Tsinghua University, Hon Hai Precision Industry Co., Ltd.
Abstract: The invention concerns a peptide derived from intermediate filaments and an intermediate filament fragment capable of altering tubulin polymerization and used for inhibiting cell proliferation, and more particularly for obtaining medicines designed to prevent or treat diseases involving cell proliferation, such as cancers for example.
Type:
Grant
Filed:
April 21, 2005
Date of Patent:
May 5, 2015
Assignees:
Universite d'Angers, Institut National de la Sante et de la Recherche Medicale (Inserm), McGill University
Inventors:
Arnaud Bocquet, Joël Eyer, Alan Peterson
Abstract: A recombinant transfer vector capable of expressing a foreign gene fused to a viral gene under the control of dual promoters and a recombinant baculovirus, and methods for production thereof, as well as pharmaceuticals comprising the recombinant baculovirus as an active ingredient.
Type:
Grant
Filed:
February 8, 2007
Date of Patent:
May 5, 2015
Assignees:
Educational Foundation Jichi Medical University, Otsuka Pharmaceutical Co., Ltd.
Abstract: The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.
Type:
Grant
Filed:
January 22, 2013
Date of Patent:
May 5, 2015
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
Hendrik Luesch, Taori Kanchan, Valerie J. Paul
Abstract: The present invention relates to conjugated polymers. In various embodiments, the present invention provides a conjugated polymer including a repeating unit including a benzene ring conjugated with the polymer backbone, wherein the benzene ring is fused to two 5-membered rings, wherein each fused 5-membered ring includes N and at least one of O and S. In various embodiments, the present invention provides semiconductor devices including the polymer, and methods of making the polymer.
Type:
Grant
Filed:
March 12, 2014
Date of Patent:
May 5, 2015
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Malika Jeffries-EL, Jeremy J. Intermann, Brian C. Tlach
Abstract: It is intended to efficiently inject into a target cell, a substance charged within a liposome. The present inventors have found that connexin synthesized within a liposome is introduced as connexon having a gap junction function into the liposome membrane. Specifically, the liposome according to the present invention is a liposome in which connexon composed of connexin synthesized by an in-vitro protein synthesis system is incorporated in a state of having a gap junction function.
Type:
Grant
Filed:
November 2, 2005
Date of Patent:
May 5, 2015
Assignees:
Tokyo Medical and Dental University, Dai Nippon Printing Co., Ltd.
Abstract: A four-wheel steering central transmission device includes an input shaft extending through a front wall of a housing and having an input rotary disc formed with a first slide groove. A turning output unit includes an output shaft extending through a rear wall of the housing and having an output rotary disc formed with a second slide groove. A transmission unit disposed between the input and output shafts includes a hollow adjustment block disposed adjustably within the housing and movable leftward or rightward, and a transmission member movable within the adjustment block and having slide pieces inserted respectively and slidably into the first and second slide grooves.
Abstract: The present invention relates to a novel human-derived cell permeable peptide-bioactive peptide conjugate and the use thereof. According to the present invention, cationic cell permeable peptides derived from human bone morphogenetic protein-4 have no toxicity and immunogenicity and thus exhibit high stability as compared to viral peptide delivery vehicles, and can transport cell impermeable material into cells and into an organism without any damage to cell or material, thereby significantly increasing target gene expression. In addition, the peptide may be applied to clinical use without having to undergo a large number of processes and mass-produced, such that the present invention may be useful in the development of a drug delivery system and treatment technologies using said peptide.
Type:
Grant
Filed:
April 25, 2011
Date of Patent:
May 5, 2015
Assignees:
Seoul National University R&DB Foundation, Nano Intelligent Biomedical Engineering Corporation Co., Ltd.
Inventors:
Chong-Pyoung Chung, Yoon-Jeong Park, Jue-Yeon Lee, Jin Sook Suh
Abstract: An electrical device includes a current transport layer formed using a layer of a topological material selected from the group of a topological insulator, a quantum anomalous hall (QAH) insulator, a topological insulator variant, and a topological magnetic insulator. In one embodiment, the current transport layer forms a conductive wire on an integrated circuit where the conductive wire includes two spatially separated edge channels, each edge channel carrying charge carriers propagating in one direction only. In other embodiments, an optical device includes an optical layer formed using a layer of the topological material. The optical layer can be a light absorbing layer, a light emitting layer, a light transport layer, or a light modulation layer.
Type:
Grant
Filed:
December 6, 2011
Date of Patent:
May 5, 2015
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: The present invention relates to a thermally conductive pad and a method for producing the same. The thermally conductive pad includes an array of carbon nanotubes and a polymer matrix. The array of carbon nanotubes has a density in the approximate range from 0.1 g/cm3 to 2.2 g/cm3. The array of carbon nanotubes is incorporated in the polymer matrix by way of polymerization of a pre-polymer of the polymer matrix in situ. Moreover, the method for producing the thermally conductive pad is also included.
Type:
Grant
Filed:
December 20, 2007
Date of Patent:
May 5, 2015
Assignees:
Tsinghua University, Hon Hai Precision Industry Co., Ltd.
Abstract: The present invention relates to nanoparticles comprising a metallic core with a surface coating, wherein the coating comprises at least an excitable radiative molecule attached thereto or impregnated therein, and wherein the excitable molecule is positioned at a sufficient distance from metallic core to enhance emissions when excited. The nanoparticles are included in compositions that may be used for surface coatings, cosmetics, assays, flow velocity measurements and targeting of tissue.
Abstract: A method and apparatus for reconstruction of a region of interest for an object is provided. The reconstruction of the object may be based on chords which may fill a part, all, or more than all of the region of interest. Using chords for reconstruction may allow for reducing data acquired and/or processing for reconstructing a substantially exact image of the ROI. Moreover, various methodologies may be used in reconstructing the image, such as backprojection-filtration, and modified filtration backprojection.
Type:
Grant
Filed:
February 20, 2012
Date of Patent:
May 5, 2015
Assignee:
The University of Chicago
Inventors:
Xiaochuan Pan, Yu Zou, Lifeng Yu, Chien-Min Kao, Martin King, Maryellen Giger, Dan Xia, Howard Halpern, Charles Pelizzari, Emil Y. Sidky, Seungryong Cho
Abstract: An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.
Type:
Grant
Filed:
June 26, 2014
Date of Patent:
May 5, 2015
Assignee:
The University of Western Australia
Inventors:
Stephen Donald Wilton, Sue Fletcher, Graham McClorey
Abstract: The present invention is directed to the synthesis of novel delaminated layered zeolite precursor materials prepared by fluoride/chloride anion-promoted exfoliation. The method comprises, for example, using a combination of fluoride and chloride anions at a mild pH in a non-aqueous solution to affect delamination of a layered zeolite precursor, generally comprising an organic solvent. The method may be used in conjunction with either acidification or sonication, or both. The resulting delaminated zeolite precursors are then isolated. Precursors that are then isolated lack amorphous silica content. The UCB-1 product is an example of such a novel oxide material and is obtained in yields in excess of 90% without the need for sonication.
Type:
Application
Filed:
December 31, 2014
Publication date:
April 30, 2015
Applicants:
Chevron U.S.A. Inc., The Regents of the University of California
Inventors:
Alexander KATZ, Isao OGINO, Stacey Ian ZONES
Abstract: In a fundus observation apparatus, an optical system detects interference light generated by superposing signal light having traveled by way of an eye fundus and reference light having traveled by way of a reference optical path. An image forming part forms a cross sectional image based on detection results of the interference light. A specifying part analyzes the cross sectional image to specify an abnormal region located in the vicinity of central fovea of the eye fundus. The association information generating part calculates the distance between the central fovea and the abnormal region and generates association information in which the direction of the abnormal region relative to the central fovea and the distance are associated with each other. The evaluation information generating part generates evaluation information for evaluating the state of the eye fundus based on the association information.