Patents Assigned to Zhejiang University
  • Patent number: 12203881
    Abstract: A method of detecting internal stress distribution of a transparent material based on X-ray diffraction, which includes the following steps. Coordinates of stress detection positions of a transparent material are established. An initial powder of the transparent material and a standard reference material are processed. A placement coordinate position of the standard reference material on the transparent material is calculated. A standard reference material-containing transparent material is synthesized. Internal stress of the standard reference material is detected as the internal stress of the transparent material at the placement coordinate position.
    Type: Grant
    Filed: April 24, 2024
    Date of Patent: January 21, 2025
    Assignee: Zhejiang University
    Inventors: Haikuo Wang, Yao Tang, Jiakun Wu, Xiaoping Ouyang
  • Patent number: 12197179
    Abstract: The present disclosure relates to non-intrusive load decomposition techniques, and aims at providing a non-intrusive load decomposition method based on an Informer model coding structure. The method includes: preprocessing power data in electricity loads, and forming sample pairs according to a time sequence of total power and a time power sequence of a single electricity load; building a training model with reference to an Informer model, the training model including a feature extraction part, a feature processing part, and a feature mapping part which are arranged in sequence; initializing parameters of the training model, and selecting an appropriate activation function and loss function; training the training model using preprocessed sample data; and inputting a total power curve to the trained model, and conducting decomposition to obtain a power curve of a single load.
    Type: Grant
    Filed: May 20, 2022
    Date of Patent: January 14, 2025
    Assignee: Zhejiang University
    Inventors: Yonggang Peng, Jiayuan Ling, Jun Chen
  • Publication number: 20250011796
    Abstract: Provided is a high-efficiency expression vector of a circular ribonucleic acid (circRNA). The high-efficiency expression vector is an expression framework with a total length of only 173 bp and having a nucleotide sequence shown in SEQ ID NO: 1, and includes an upstream frame sequence of 92 bp, a downstream frame sequence of 75 bp, and a restriction site EcoR I located between the upstream and downstream frame sequences for inserting a gene to be circularized. In the present disclosure, the high-efficiency expression vector of a circRNA can enable an exogenously-inserted sequence to efficiently express the circRNA, thus providing an efficient expression tool for obtaining the circRNA. On the premise of ensuring efficient circularization of the circRNA, lengths of upstream and downstream flanking sequences required for the circularization have been highly optimized to further reduce the complexity of splicing by-products caused by the flanking sequences.
    Type: Application
    Filed: July 3, 2024
    Publication date: January 9, 2025
    Applicant: Zhejiang University
    Inventors: Jiyong ZHOU, Liuyang DU, Jinyan GU, Yan YAN, Yulan JIN, Weiren DONG
  • Patent number: 12190530
    Abstract: A dense optical flow calculation system and method based on an FPGA (Field Programmable Gate Array) are provided. The system comprises a software system deployed on a host and a dense optical flow calculation module deployed on the FPGA. Pixel information of two continuous frames of pictures is obtained from a host end in the system, and optical flow is obtained by calculation by means of the steps such as smoothing processing, polynomial expansion, intermediate variable calculation, optical flow calculation. An image pyramid and iterative optical flow calculation can be achieved by repeatedly calling a calculation core module in the FPGA; a final calculation result is returned to the host end.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: January 7, 2025
    Assignee: Zhejiang University
    Inventors: Xiaohong Jiang, Zhe Pan, Jian Wu
  • Patent number: 12189766
    Abstract: A microgrid self-triggering control method and system for resisting FDI attacks is provided. The method includes the following steps: S1: adopting primary control based on droop control for a microgrid; S2: designing a secondary control strategy of the microgrid, where the secondary control strategy includes frequency recovery and fair distribution of active power; and S3: designing a microgrid distributed self-triggering control method of a hash encryption method after considering the condition that the FDI attacks are injected into a secondary control communication link, so as to resist false malicious data in the microgrid and achieve secondary control. According to the microgrid self-triggering control method and system, a distributed secondary control target of the microgrid is achieved even under the FDI attacks, the injected malicious data can be quickly detected and eliminated, and the distributed secondary control communication network of the microgrid can be protected.
    Type: Grant
    Filed: August 12, 2024
    Date of Patent: January 7, 2025
    Assignees: Hainan Research Institute of Zhejiang University, Zhejiang University
    Inventors: Yulin Chen, Donglian Qi, Xing Huang, Yunfeng Yan, Shenjun Weng, Xianbo Wang
  • Publication number: 20250002580
    Abstract: The present invention relates to the field of biomedicine, and discloses use of a PD1 inhibitor in preparation of an inhibitor for cardiac fibroblast transdifferentiation. The present invention found through cell and animal experiments that the PD1 inhibitor can reduce the transdifferentiation level of cardiac fibroblasts after myocardial infarction. The present invention not only provides a therapeutic drug or strategy for myocardial infarction, but also provides a tool drug for the study of transdifferentiation of cardiac fibroblasts.
    Type: Application
    Filed: December 9, 2022
    Publication date: January 2, 2025
    Applicant: Zhejiang University
    Inventors: Xinyang HU, Jian'an WANG, Xiaoying CHEN, Changle KE
  • Publication number: 20250005475
    Abstract: An engineering progress determination method based on a multi-modality temporal information fusion includes: acquiring current engineering progress information of multiple modalities and corresponding historical engineering progress information for current engineering progress information of each modality; subsequently, extracting modality-specific temporal features from both current engineering progress information and historical engineering progress information; these modality-specific temporal features are then fed into a dimension decoupling-based multi-modality fusion module, resulting in fused multi-modality temporal information; and the current engineering progress is then determined based on this fused information.
    Type: Application
    Filed: June 6, 2024
    Publication date: January 2, 2025
    Applicants: Hangzhou Newgrand Technology Co., Ltd., Zhejiang University, Hangzhou HaoLink Intelligent Technology Co., Ltd.
    Inventors: Lanfen Lin, Hongyi Wang, Hao Sun, Zhongshao Shi, Hong Xu
  • Patent number: 12180304
    Abstract: The present disclosure provides a variable region sequence of a broad-spectrum antibody against clothianidin and dinotefuran, where a gene encoding a heavy chain variable region has an amino acid sequence shown in SEQ ID NO: 2. The present disclosure further discloses a broad-spectrum intact recombinant antibody against clothianidin and dinotefuran, including a heavy chain constant region, a heavy chain variable region, a light chain constant region, and a light chain variable region, where a gene encoding the heavy chain variable region has an amino acid sequence shown in SEQ ID NO: 2. The sequence genes obtained by the present disclosure are ligated to an expression vector containing a heavy chain constant region gene and a light chain constant region gene, respectively, and an intact recombinant antibody is expressed and obtained by using mammalian cells with a double-plasmid system.
    Type: Grant
    Filed: July 28, 2021
    Date of Patent: December 31, 2024
    Assignee: Zhejiang University
    Inventors: Yirong Guo, Yunyun Chang, Ying Zhao, Pengyan Liu, Ying Liu, Yang Chen, Guonian Zhu
  • Patent number: 12182700
    Abstract: The present disclosure discloses a method for deriving fault diagnosis rules of a blast furnace based on a deep neural network, which relates to the field of industrial process monitoring, modeling and simulation. Firstly, a deep neural network is used to model historical fault data of the blast furnace. Then, for each kind of fault, the process starts from the output layer of the network, wherein sub-models of nodes in the adjacent layers in the deep neural network are established by using the decision tree in sequence, and the if-then rule is derived. Finally, the if-then rules are merged layer by layer, so as to finally obtain fault diagnosis rules of the blast furnace with blast furnace process variables being the rule antecedents and with fault categories being the rule consequents.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: December 31, 2024
    Assignee: Zhejiang University
    Inventors: Xiaoke Huang, Chunjie Yang
  • Patent number: 12173017
    Abstract: A BMOFs nanosheet based on a ZIF/MIL topology, and a preparation method and an application thereof are provided. The preparation method includes dispersing a MOF material of a ZIFs series in an organic phase, then adding an aqueous phase to obtain a mixture; and adding a MOF material of a MILs series into the mixture, sealing, standing for 1-5 days, filtering, performing centrifugal washing, drying, and performing acetone ultrasonic exfoliation to obtain the BMOFs nanosheet based on the ZIF/MIL topology. The preparation method is simple to operate and moderate in conditions, and the prepared ZIF/MIL BMOFs nanosheet has good electrocatalytic activity and stability in an OER.
    Type: Grant
    Filed: May 3, 2024
    Date of Patent: December 24, 2024
    Assignees: Zhejiang University of Technology, Zhejiang Marine Fisheries Research Institute
    Inventors: Lei Qin, Xiaoyan Mao, Tiejun Li, Yingyu Tan, Wenjie Liu, Lei Jin
  • Patent number: 12161970
    Abstract: A CO2 desorption system suitable for limited space in a complex sailing region comprises an exhaust boiler, a compact CO2 absorber, a compact CO2 lean-rich liquid heat exchanger, a compact CO2 desorber, a compact CO2 rich liquid preheating device, a compact CO2 rich liquid reboiling pre-desorption device and an intelligent control platform. Further, a global optimization control method for the CO2 desorption system suitable for limited space in a complex sailing region is further established based through a knowledge and data-driven exhaust extraction flow accurate-prediction model for a heat source of a CO2 rich liquid preheating device and a steam extraction flow accurate-prediction model for a heat source on an upper section of a CO2 rich liquid reboiling pre-desorption device to realize flexible control of operation parameters of the desorption system under different operating conditions of an engine.
    Type: Grant
    Filed: August 9, 2024
    Date of Patent: December 10, 2024
    Assignees: Jiaxing Research Institute, Zhejiang University, Zhejiang University
    Inventors: Chenghang Zheng, Xiang Gao, Can Zhou, Yongxin Zhang, Qihao Chen, Weihong Wu, Zhiying Zhou, Haitao Shen, Haidong Fan, Qingyi Li, Yifan Wang, Peng Liu, Libin Yu, Tao Wang
  • Patent number: 12166346
    Abstract: A fully distributed island micro-grid attack elasticity control system and method are provided. The method includes following specific steps: collecting basic information of a local AC micro-grid bus of a distributed power generation unit and basic information of a neighbor distributed power generation unit connected through a directed communication topology; predicting, based on a dynamic equation of the distributed power generation unit, a sequence of states thereof within a set period of time, namely, the predicted sequence of states; judging whether a system is under attack according to a comparison result of the predicted sequence of states and a real-time state sampling value of a micro-grid, to obtain a sequence of optimal auxiliary control inputs ui*; and calculating an optimal angular frequency reference value ?i* at the next time point according to the sequence of optimal auxiliary control inputs ui*.
    Type: Grant
    Filed: April 30, 2024
    Date of Patent: December 10, 2024
    Assignees: Zhejiang University, Hainan Research Institute of Zhejiang University
    Inventors: Donglian Qi, Xueqi Wang, Yunfeng Yan, Guangxin Zhi, Dawang Fu
  • Publication number: 20240392334
    Abstract: Provided is a bacterial cellulose-producing Komagataeibacter europaeus strain FMES and use thereof. The strain FMES is deposited in the China Center for Type Culture Collection (CCTCC) with a deposit number of CCTCC NO: M20221627. The strain FMES is isolated from traditional vinegar brewing and can efficiently produce bacterial cellulose through static culture. The strain FMES can also be used to produce a novel, green, and non-toxic degradable biotextile. Therefore, the strain FMES is expected to replace leather, textiles, and films derived from animals, plants, and petrochemicals, and shows a potential to serve as a sustainable alternative of the textiles.
    Type: Application
    Filed: January 16, 2024
    Publication date: November 28, 2024
    Applicants: Innovation Center of Yangtze River Delta, ZJU, Zhejiang University
    Inventors: Qihe CHEN, Siyu LIU, Ying SHI, Qianhui QI
  • Patent number: 12151204
    Abstract: A catalytic oxidation system for efficient conversion and removal of volatile organic compounds (VOCs) in a coal chemical industry is provided. The catalytic oxidation system includes a reactor and a first temperature control system, where the reactor is provided with a waste gas inlet and a waste gas outlet and is provided with a preheating zone, a reaction zone, and a heat recovery zone sequentially in a flow direction of a waste gas, and a catalyst is filled in the reaction zone; and the first temperature control system includes a first serpentine pipe buried in the catalyst and a first steam drum arranged outside the reactor, the first steam drum and the first serpentine pipe are connected through a pipeline to form a circulation line, and a temperature in the reaction zone is adjusted to 150° C. to 350° C. by controlling a pressure of the first steam drum.
    Type: Grant
    Filed: May 8, 2024
    Date of Patent: November 26, 2024
    Assignees: Zhejiang University, Taizhou Institute of Zhejiang University
    Inventors: Shengyong Lu, Bing Zhou, Yaqi Peng, Minghui Tang, Kai Zhang, Hao Zhang, Jiamin Ding, Guanjie Wang
  • Publication number: 20240382539
    Abstract: The present disclosure provides use of an intestinal probiotic in preparation of a medicament that promotes metabolism of ellagic acid (EA) into urolithin A, a pharmaceutical composition and use thereof, and belongs to the technical field of biomedicine. In the present disclosure, probiotics capable of changing metabotypes of EA are selected from a plurality of probiotics. These probiotics alone or in combination can change an intestinal flora structure of a metabotype B and/or 0 population, thereby improving the efficiency of the metabolism of EA into urolithin A and increasing a yield of urolithin A. The present disclosure provides an intestinal probiotic for involving in and promoting the metabolism of EA into urolithin A, and provides a new idea for the treatment of diabetes, obesity, senescence, and diseases caused by central nervous system lesions and viral infection using urolithin A as an active pharmaceutical ingredient.
    Type: Application
    Filed: August 2, 2023
    Publication date: November 21, 2024
    Applicant: Zhejiang University
    Inventors: Haibo PAN, Laiming ZHANG, Shiguo CHEN, Xingqian YE, Donghong LIU, Tian DING
  • Patent number: 12146817
    Abstract: A micro-zone soil sampling apparatus and method for different contamination situations. The apparatus includes an uncovered cylinder and a plurality of circular separators. The circular separators are vertically arranged in a hollow inner cavity of the uncovered cylinder, and are removably connected to an inner wall of the uncovered cylinder. Each circular separator includes a plurality of inner rings arranged coaxially, an outer ring coaxially arranged outside the inner rings, and a soil-bearing net. Each circular separator is divided into multiple hollow spaces by the inner rings and the outer ring. The inner rings made of a permeable membrane material and the outer ring made of a rigid material both have a certain thickness. The soil-bearing net is fittedly fixed on a bottom of each circular separator. A plurality of spokes passing through a center of the soil-bearing net are fixedly arranged on the soil-bearing net.
    Type: Grant
    Filed: December 27, 2022
    Date of Patent: November 19, 2024
    Assignee: Zhejiang University
    Inventors: Baolan Hu, Meng Zhou, Wenda Chen, Jiaqi Wang
  • Publication number: 20240375757
    Abstract: Some embodiments of the disclosure provide a cooperative positioning system and method for an unmanned underwater vehicle (UUV) cluster based on ranging and information interaction. In some examples, the cooperative positioning system includes one master UUV, multiple slave UUVs, and a cooperative positioning apparatus. In some examples, the cooperative positioning method includes following steps. A master UUV and a slave UUV perform internal clock disciplining. The master UUV periodically packages a location of the master UUV and a covariance matrix of location estimation into a cooperative positioning data packet and broadcasts the cooperative positioning data packet to slave UUVs of a cluster. The slave UUV receives the cooperative positioning data packet. A cooperative positioning apparatus of the salve UUV constructs a state and a measurement equation according to data. The cooperative positioning apparatus calculates and obtains a cooperative positioning result by using an extended Kalman filter (EKF).
    Type: Application
    Filed: May 12, 2023
    Publication date: November 14, 2024
    Applicant: Zhejiang University
    Inventors: Huifang Chen, Lei Xie, Feng Liu, Wen Xu
  • Publication number: 20240368841
    Abstract: The method of the present invention specifically comprising following steps: adding a chitosan to an acetic acid solution, heating and stirring until clear, to obtain an acidic chitosan solution; then adding a palm wax and heating a resulting mixture to 80-100° C. with a constant temperature and a high-speed stirring for emulsification for 5-15 minutes; after the emulsification is completed, an obtained emulsion is quickly cooled to a room temperature. The present invention uses a single-layer coating method to prepare waterproof and oil-proof food cardboard, simplifying operation and achieving good waterproof, oil-proof, and antibacterial effects with a lower coating amount, thereby reducing production costs. When a coating amount is 5-10 g/m2, a Cobb60 value can reach 5-9 g/m2, an oil resistance level can reach 11-12 levels, a water contact angle can reach over 130°, and an antibacterial rate can reach over 90%.
    Type: Application
    Filed: April 29, 2024
    Publication date: November 7, 2024
    Applicant: Zhejiang University of Science and Technology
    Inventors: Lizheng SHA, Feiyang ZHANG, Daliang GUO, Huifang ZHAO, Jing LI, Yinchao XU
  • Patent number: 12131484
    Abstract: A multi-object tracking method based on authenticity hierarchizing and occlusion recovery relates to the technical field of multi-object tracking for security management and control of complex scenes. The method includes the following steps: image acquisition, object detection, authenticity hierarchizing, hierarchical association and outputting tracks. The multi-object tracking method is helpful to solve the long-term puzzling occlusion problem in the field of multi-object tracking, the constructed new algorithm framework can achieve an advanced tracking performance, improve the adaptability of the method to complex environments, and adapt to more difficult video surveillance security control tasks.
    Type: Grant
    Filed: June 4, 2024
    Date of Patent: October 29, 2024
    Assignee: Zhejiang University
    Inventors: Yunfeng Yan, Haoyuan Jin, Donglian Qi, Qi Li, Rui Han, Bingxiao Mei, Zezhou Wang, Gang Chen
  • Patent number: 12132711
    Abstract: A privacy protection method and system for financial data sharing based on federated learning are provided. In recent years, due to the restrictions of data security and privacy protection laws and regulations, it is difficult to share data across institutions or departments. In order to make data transfer and transaction between different entities can be achieved without violating the national laws on data privacy and data security, the privacy protection method and system for financial data sharing based on federated learning is provided. A privacy collection intersection technology is adopted, so that two institutions, which may have many differences in business, but most of their customer groups are the same, jointly train a learning model.
    Type: Grant
    Filed: September 9, 2022
    Date of Patent: October 29, 2024
    Assignees: Zhejiang University City College, Zhejiang Gongshang University, Beihang Hangzhou Innovation Institute Yuhang
    Inventors: Song Han, Siqi Ren, Minghui Wu, Shuai Zhao, Xiling Luo, Luyao Wang