Abstract: Methods and systems for detecting the presence of irregularities in milk, and for assessing a health state of a lactating mammal, are provided. A sample of milk is illuminated with a light beam. Scattering data resulting from an interaction between the light beam and the sample of milk is collected. The scattering data is processed to detect the presence or absence of light scattered at a predetermined angle relative to a normal orientation, for instance to determine at least one characteristic of the sample of milk. Based on the presence or absence of light, the presence of irregularities in the sample of milk can be determined, for instance to assess the health state of the lactating mammal based on the at least one characteristic of the sample of milk.

Abstract: The invention relates to a sensor module (1) for multiparametric analysis of a medium (105) and to the uses thereof. The sensor module (1) according to the invention is characterised by a combination of photonic and non-photonic measurement principles with parameter-sensitive coatings (103) on a substrate (100). A plurality of properties of a medium (105) can be detected over wide parameter ranges, wherein the most suitable method can be used for the corresponding parameter, at least for example with regard to the accuracy, the long-term stability, the resolution, the reproducibility, the energy consumption, the manufacturing costs, the necessary space requirements.

Abstract: The present invention teaches an apparatus for consistent and accurate on-site readings of fluorescence signals of coronavirus test result, with which a user directly reads a fluorescent light qualitatively instead of using electronic sensors. The fluorescent light is excited from a fluorescent source in a site of interest in a target assay. The device comprises a light source for generating an excitation light for exciting the fluorescent source of the target assay to generate a fluorescent light, a component for accurately transmitting the excitation light and the fluorescent light with less noise or reflection, a component for consistent detecting of the fluorescent source by bare eyes with minimal health risks, and a user control system that requires minimal training.

Abstract: The present invention provides an information processing apparatus for determining, for a substrate having undergone an imprint process that forms a pattern of an imprint material, presence/absence of a formation defect of the pattern, including a generating unit configured to generate learning models in one-to-one correspondence with a plurality of different illumination conditions by using images obtained by capturing images of a plurality of substrates on which the pattern is formed under the plurality of illumination conditions, and an obtaining unit configured to input the images obtained by capturing images of the substrates having undergone the imprint process and containing the pattern, to a plurality of learning models generated by the generating unit, and obtain a temporary determination result temporarily indicating the presence/absence of a formation defect of the pattern from each of the plurality of learning models.

Abstract: A method of analyzing particles present in a service fluid of a device includes analyzing the particles during operation of the device where a service fluid flows through a service fluid circuit of the device during the analyzing. The method further includes branching off a service fluid stream at a first branch point of the service fluid circuit, feeding the branched-off service fluid stream to a separation unit, branching the branched-off service fluid stream into a first service fluid stream and a second service fluid stream by the separation unit, feeding a majority of particles present in the branched-off service fluid stream to the first service fluid stream by the separation unit, and ascertaining at least one parameter of the particles fed to the first service fluid stream by an evaluation unit.

Abstract: This disclosure describes inputting pulsated pump light in a fundamental mode or a first higher-order mode into one end of an optical fiber under test constructed by connecting two optical fibers in series; inputting probe light having an optical frequency difference within a Brillouin frequency shift range with respect to the pump light into the other end of the optical fiber under test in the fundamental mode or the first higher-order mode; measuring a Brillouin gain distribution related to a distance of transmitted light intensity of probe light output from the one end into which the pump light was input; and calculating each inter-modal coupling efficiency at the connection point of the optical fiber under test.

Abstract: A calibration curve setting method used at the time of quantitatively analyzing specific components in a drug by a transmission Raman spectrum, the method comprising the steps of: obtaining respective transmission Raman spectra of a plurality of different wave number ranges including Raman hands corresponding to the specific components of a plurality of known drugs of which concentrations or amounts of the specific components are known and the concentrations or the amounts are different from each other; calculating candidate calibration curves which are candidates for calibration curves used for the quantitative analysis respectively from a plurality of transmission. Raman spectra in each of the wave number ranges; and using the most probable candidate calibration curve as a calibration curve for the quantitative analysis of the specific components, among the respective candidate calibration curves.

Abstract: A substrate misalignment detection method includes: acquiring first image information or first position information of a substrate held to a stage by suction at a first height position; delivering the substrate from the stage to a holder in a state in which the suction of the substrate is released and causing the holder to hold the substrate at the first height position; acquiring second image information or second position information of the substrate held at the first height position; and detecting misalignment of the substrate by comparing the first image information with the second image information or by comparing the first position information with the second position information.

Abstract: Aspects of the present disclosure include methods for producing an output laser beam having two or more angularly deflected laser beams (e.g., for irradiating a sample in a flow stream) with a predetermined intensity profile. Systems for practicing the subject methods having a laser, an acousto-optic device, a radiofrequency generator and a controller for adjusting the amplitude of the radiofrequency drive signals to produce an output laser beam of angularly deflected laser beams with a predetermined intensity profile are also described.

Abstract: The technology disclosed relates to determining positional information of an object in a field of view. In particular, it relates to measuring, using a light sensitive sensor, one or more differences in an intensity of returning light that is (i) emitted from respective directionally oriented non-coplanar light sources of a plurality of directionally oriented light sources that have at least some overlapping fields of illumination and (ii) reflected from the target object as the target object moves through a region of space monitored by the light sensitive sensor, and recognizing signals in response to (i) positional information of the target object determined based on, a first position in space at a first time t0 and a second position in space at a second time t1 sensed using the measured one or more differences in the intensity of the returning light and (ii) a non-coplanar movement of the target object.

Abstract: A method for measuring a concentration of molecules, characterized in that the method measures the concentration of molecules dissolved in a continuous phase of a colloid and includes obtaining a test sample by mixing a number of molecules with a volume of colloid, obtaining a control sample by mixing a number of molecules with a volume of a composition comprising a particle-free solution extracted from a fraction of the continuous phase of same colloid used in the obtaining the test sample, so that a value of the concentration of molecules in the mixture is equal to the value of the concentration of molecules in the test sample obtained in the obtaining the test sample, and submitting the test and the control samples obtained in the obtaining the test sample and obtaining the control sample to a process in order to concentrate the particles of the test sample.

Abstract: A method for verifying semiconductor wafers includes receiving a semiconductor wafer including a plurality of layers. A first set of measurement data is obtained for at least one layer of the plurality of layers, where the first set of measurement data includes at least one previously recorded thickness measurement for one or more portions of the at least one layer. The first set of measurement data is compared to a second set of measurement data for the at least one layer. The second set of measurement data includes at least one new thickness measurement for the one or more portions of the at least one layer. The semiconductor wafer is determined to be an authentic wafer based on the second set of measurement data corresponding to the first set of measurement data, otherwise the semiconductor is determined to not be an authentic wafer.

Abstract: A flow cytometer, laser optics assembly thereof, and methods of assembling the same are provided. The flow cytometer is capable of yielding consistent and accurate results despite exposure to adverse environmental conditions such as, for example, temperature changes within a relatively wide temperature range and/or a relatively large amount of random-axis mechanical vibration. The flow cytometer of the present disclosure is additionally or alternatively relatively insensitive to real or apparent core stream shifts, employs a slowly converging beam along the axis perpendicular to core stream flow, and provides the ability to precisely measure time-of-flight.

Abstract: A device for measuring a light radiation pressure is provided which includes a torsion balance, a laser, a convex lens, and a line array detector. The laser is configured to emit a first laser beam. The convex lens is located on an optical path of the first laser beam and configured to focus the first laser beam to a surface of the reflector. The line array detector is configured to detect a reflected first laser beam reflected by the reflector. The disclosure also provides a method for measuring the light radiation pressure using the device.

Abstract: A quasi-soft catcher, a quasi-soft capture device, and a method for using the same are provided. The quasi-soft catcher includes a base and a plurality of protruding structures for capturing at least one target biological particle from a specimen. The protruding structures are regularly arranged on a board surface of the base. Each of the protruding structures includes an outer portion configured to touch the at least one target biological particle and an inner portion that is connected between the board surface and the outer portion, and a structural strength of the inner portion is less than that of the outer portion. The board surface has an interspace region arranged outside of the protruding portions, and the interspace region occupies 20-80% of the board surface.

Abstract: An assembly includes an optical element having a light-shaping region. A light emitter is aimed into the optical element along an internal reflective path. The internal reflective path extends across the light-shaping region. A photodetector is positioned along the internal reflective path. Integrity of the optical element is determined based on detection of light from the light emitter along the internal reflective path by the photodetector.

Abstract: One example provides a system for reading birefringent data. The system comprises one or more light sources, a first polarization state generator positioned to generate first polarized light from light of a first wavelength band output by the one or more light sources, a second polarization state generator positioned to generate second polarized light from light of a second wavelength band output by the one or light sources, an image sensor configured to acquire an image of the sample region via the first polarized light and the second polarized light, a polarization state analyzer disposed between the sample region and the image sensor, a first bandpass filter configured to pass light of the first wavelength band onto the image sensor, and a second bandpass filter configured to pass light of the second wavelength band onto the image sensor.

Abstract: An adhesion defect detection apparatus includes an inspection window having a first dummy area, a second dummy area, and an inspection area disposed between the first dummy area and the second dummy area. A first shape changer is disposed on the inspection window. The first shape changer is configured to change a shape of the inspection window in a first direction. A second shape changer is disposed outside of both the first dummy area and the second dummy area. The second shape changer is configured to change a shape of the inspection window in a second direction that is perpendicular to the first direction.

Abstract: A method of processing a substrate according to a PECVD process is described. Temperature profile of the substrate is adjusted to change deposition rate profile across the substrate. Plasma density profile is adjusted to change deposition rate profile across the substrate. Chamber surfaces exposed to the plasma are heated to improve plasma density uniformity and reduce formation of low quality deposits on chamber surfaces. In situ metrology may be used to monitor progress of a deposition process and trigger control actions involving substrate temperature profile, plasma density profile, pressure, temperature, and flow of reactants.

Abstract: The present application discloses a sensor system that includes a sensor having a sensor surface, a sample cartridge including one or more flexible membranes and a membrane frame, the membrane frame including one or more openings covered by the one or more flexible membranes defining one or more wells for holding one or more samples, the flexible membrane having a sample side supporting the sample and an opposite sensor side, the sample cartridge being removably insertable in the sensor system such that the sensor side of the flexible membrane is positioned above and faces the sensor surface, a displacement mechanism that can be actuated to displace the flexible membrane toward the sensor surface such that the sample is moved to a position closer to the sensor surface, and an optical imaging system that detects light emitted from the sensor. Disclosed also are a cartridge cassette and a method of use.