Abstract: A method for locating a center of a field of view of an optical element using a system having a surface disposed at a first illumination, an image receiver, a blocker disposed at a second illumination, the method including disposing the blocker at, at least one location in the field of view upon the surface in a first direction when the brightness of an image within the field of view of the optical element is disposed at a brightness and recording a first location of the blocker; repeating the disposing step in a second direction and at the brightness, wherein the second direction is opposite the first direction and each of the first direction and the second direction is parallel to the surface; and averaging the first location and the second location to yield the center of the field of view of the optical element in the first direction.

Abstract: The present technology relates to an information processing device capable of obtaining an index effective for a measurement target as an index related to light incident on the measurement target, an information processing method, and a program. The information processing device can obtain an index effective for a measurement target as an index regarding light incident on the measurement target by calculating an effective index representing the degree of light effectively utilized for the measurement target in incident light as an index regarding the light incident on the measurement target, on the basis of a measured value regarding the measurement target which is obtained by sensing performed by a sensor. The present technology can be applied to, for example, an apparatus calculating an index of plants.

Abstract: A high-temperature and high-pressure equipment and method for microscopic visual sulfur deposit seepage test is provided by the present disclosure, the equipment comprises an injection system, a high-temperature and high-pressure visual kettle, a pressure supply system, a data acquisition and analysis system, a fluid recovery system, and an injection branch pipe; the injection system comprises an ISCo micro-injection pump, an intermediate container, a thermostatic heating oven and a pressure meter; the intermediate container is arranged in the thermostatic heating oven, the ISCo micro-injection pump is connected to the intermediate container; the data acquisition and analysis system comprises a microscope, a high-brightness light source and a computer; the pressure supply system comprises an annular pressure tracking pump, a back pressure pump, a back pressure valve and a pressure gauge; the fluid recovery system comprises a wide neck flask with rubber stopper, a balance, a flowmeter and an exhaust gas absorb

Abstract: A method of performing metrology analysis of a thin film includes coupling a radiation into an optical element disposed adjacent to a surface of the thin film. The radiation is coupled such that the radiation is totally internally reflected at an interface between the optical element and the thin film. An evanescent radiation generated at the interface penetrates the thin film. The method furthers include analyzing the evanescent radiation scattered by the thin film to obtain properties of the thin film.

Abstract: The objective of the present invention is to provide a particle detection device and a particle detection method that can individually and continuously detect a wide range of particles. The objective is achieved by a particle detection device including: a particle separation channel through which particles are separated according to particle sizes in a perpendicular direction to the flow of fluid; and two or more particle recovery channels that are connected to and branched from the particle separation channel, in which each of the particle recovery channels includes a particle detection unit that includes an aperture and an electric detector.

Abstract: A process for sizing two-dimensional nanostructures includes providing the nanostructures to a liquid-liquid interface, providing probe particles to the liquid-liquid interface, obtaining an image of the nanostructures and the probe particles, and processing the image to ascertain a size property of the nanostructures.

Abstract: Disclosed is a method for capturing target cells or molecules in solution, comprising steps of: (I) getting medium containing said target cells or molecules into an apparatus comprising a capturing device for capturing said target cells or molecules; (II) getting said medium flow through said capturing device; (III) removing unbound debris, cells and molecules; (IV) getting said target cells or molecules detached from the capturing device; and (V) collecting said target cells or molecules; wherein said capturing device comprises at least one functionalized mesh comprising a mesh substrate and a functional layer formed on said mesh substrate, wherein said functional layer comprises capturing substances that can specifically bind with said target cells or molecules. The method has high specificity, as well as high throughput, and is suitable for capturing cells or molecules in a solution or expressed at the surface of cell membranes. It is particularly suited to capture and sort circulating tumor cells.

Abstract: A crack detection method includes a crack forming step of applying a laser beam to a plate-shaped workpiece that has a first side and a second side opposite to the first side linearly from the first side with a focal point of the laser beam positioned inside the workpiece, the laser beam being of a wavelength having a transmitting property to the workpiece, to thereby form a modified layer inside the workpiece and further form a crack extending from the modified layer toward the second side, a coating material applying step of applying a coating material to the second side, and a crack detecting step of detecting the crack by searching for a portion where the coating material is linearly repelled.

Abstract: A particulate matter sensor including a light source, a photodetector, and a particle filter. The light source and the photodetector are arranged in the same plane as the particle filter. Integrated particulate matter sensors are operable to detect particulate matter by measuring an optical characteristic of a filter.

Abstract: Provided is a fluid analysis apparatus and a method of controlling the same. The fluid analysis apparatus include an actuator provided on a part of the fluid analysis apparatus, a mounting portion on which a fluid accommodating cartridge is mounted thereon, the fluid accommodating cartridge provided with a well in which a fluid sample is accommodated, a measurement portion configured to transmit light to the fluid accommodating cartridge and detect an optical signal from the light passed through the fluid accommodating cartridge, and a controller configured to control an operation of the actuator based on the optical signal detected by the measurement portion such that the light transmitted from the measurement portion passes through a central portion of the well to perform an accurate inspection on the fluid sample.

Abstract: An object of the present claimed invention is to improve cell cooling performance, keep a temperature of a dispersion medium constant, and improve measurement accuracy. The particle size distribution measuring device of this invention comprises a cell holding body 31 that holds a cell 2 housing a measurement sample and that is rotated by a motor 322, a case (C) having a housing space (S) for rotatably housing the cell holding body 31, and a cooling mechanism 8 for cooling the cell 2. The cooling mechanism 8 comprises a cooler 81, and a supply channel 82 that supplies a gas that has been cooled by the cooler 81 to the housing space (S).

Abstract: An apparatus and method for testing dissolution properties of a drug, especially anti-inflammatory drugs administered by aerosol into the respiratory system. The apparatus shortens the time it takes for a drug to dissolve and thus provides for rapid testing of new drugs for quality control as well as for regulatory purposes. It is suitable for evaluating bioequivalence or to study the pharmacokinetics of drugs administered into the respiratory system. This method shortens dissolution times for testing a drug to about 10 and 20 minutes and thus provides for rapid testing.

Abstract: A mold sensor is configured with an enclosed chamber in which a nutrient-treated substrate is positioned. The mold sensor includes a sensing system that is configured to measure properties of pressure waves within the enclosed chamber. A controller operates the sensing system and is programmed to detect a presence of mold growing in the chamber based on the characteristics of the pressure wave response within the chamber.

Abstract: A method can be provided for analyzing a fluidic sample with dispersed particles. Using such exemplary method, it is possible to irradiate the sample with light, so that the photons of the light transfer momentum to the particles. It is also possible to measure at least one property of the particles that is altered by the momentum transfer. The light can be a propagating beam with an intensity distribution that has gradients pointing to more than one point within each plane normal to the direction of propagation, while varying steadily along the direction of propagation, and/or a 3D vortex trap beam that is configured to confine the particles in a three-dimensional volume by means of high-intensity gradients. An exemplary device can also be provided (e.g., for performing the method), comprising a chamber for holding a sample that is elongate along an axis and configured to pass a beam of light along the axis.

Abstract: Metrology targets and methods are provided, which comprise at least two overlapping structures configured to be measurable in a mutually exclusive manner at least at two different corresponding optical conditions. The targets may be single cell targets which are measured at different optical conditions which enable independent measurements of the different layers of the target. Accordingly, the targets may be designed to be very small, and be located in-die for providing accurate metrology measured of complex devices.

Abstract: Corrosion detection systems and methods can include at least one fiber optic cable embedded in a material having at least two layers. Two of the layers can define an interface, and the fiber optic cable can be embedded at the interface. Each fiber optic cable can have a plurality of Fiber Bragg Gratings (FBG's) formed therein at predetermined intervals. Each FBG can have a preselected geometry that can only allow a predetermined light wavelength to pass therethrough. A light source for inputting light and a photodetector can be connected to opposite exposed ends of the fiber optic cable. As corrosion occurs near an FBG, it experiences mechanical strain, which can further cause a slightly different wavelength to pass through the fiber optic cable. The change in in wavelength can be detected by the photodiode as being indicate of corrosion occurring at the site near the FBG.

Abstract: An ore volume-based zonal injection method for ionic rare earth includes six steps of ore body data acquisition; ore volume calculation by units; calculation of leaching agent consumption ? per unit ore volume; calculation of unit ore volume-based zoning range difference; merging of the units into injection zones; and injection.

Abstract: A fluid analyzer includes an optical source and detector defining a beam path of an optical beam, and a fluid flow cell on the beam path defining an interrogation region in a fluid channel in which the optical beam interacts with fluids. One or more flow-control devices conduct a particle in a fluid through the fluid channel. A motion system moves the interrogation region relative to the fluid channel in response to a motion signal, and a controller (1) generates the motion signal having a time-varying characteristic, (2) samples an output signal from the optical detector at respective intervals of the motion signal during which the interrogation region contains and does not contain the particle, and (3) determines from output signal samples a measurement value indicative of an optically measured characteristic of the particle.

Abstract: A method to measure the refractive index of a sample, includes: providing a plasmonic sensor including a sensing surface in contact with the sample; providing an optical resonator, the plasmonic sensor being integrated therein as a reflecting surface; providing a first input field of electromagnetic radiation as a primary carrier; providing a second input field of electromagnetic radiation as a secondary carrier having a second frequency different from the first and defined as: second frequency=first frequency+?v and having a TE and/or a TM polarized component; impinging simultaneously with the first and second input field the plasmonic sensor; tuning the frequency of the first field and/or the value of ?v; detecting a resonator output power corresponding to the first and second intra-cavity fields resonating; determining a difference between the first and the second resonating frequencies; and calculating the refractive index of the sample from the difference.

Abstract: Flow cytometers having an enclosed particle sorting module are provided. Aspects of the flow cytometers include, in addition to the enclosed particle sorting modules, a sample input module fluidically coupled to an inlet of the enclosed particle sorting module, a waste reservoir fluidically coupled to first outlet of the enclosed particle sorting module and a first sorted particle collection system fluidically coupled to a second outlet of the enclosed particle sorting module. Flow cytometers as described herein are configured to control aerosol content in the enclosed particle sorting modules, including the sort chambers of such modules. Also provided are methods of using the flow cytometers, as well as kits that include one or more components of the flow cytometers are consumables for use therewith.