Abstract: In one example, a textile fastener may include a pegging member, and a receiving member. The receiving member may include a flange portion configured to support at least a portion of the textile, and an opening disposed within the flange portion configured to receive the pegging member. In some cases, the pegging member may be configured to apply a friction force between the textile and the receiving member when the pegging member is inserted into the opening. Magnetic interaction between the pegging member and the receiving member may maintain the friction force between the textile and the receiving member.

Abstract: A sequence code verification system can be designed to include a data reader, a validity engine, and an error notifier. The data reader can read sequence codes from consecutive logical blocks. The validity engine can invalidate write operations in response to checking data validity by applying comparison operations to sequence codes and block offsets of batch write operations. The error notifier can notify a user of an error for each invalidated write operation batch. The system can validate data written to logical blocks on a storage subsystem adapted so that, during write operations, an additional sequence code is written to each logical block of data. The sequence code can remain constant for each write operation batch and the sequence code can be incremented for each new write operation batch.

Abstract: Compositions and methods comprising bioenergetic agents for restoring the quality of aged oocytes, enhancing oogonial stem cells or improving derivatives thereof (e.g., cytoplasm or isolated mitochondria) for use in fertility-enhancing procedures, are described.

Abstract: Provided herein are methods and compositions for enhancing the cognitive performance of a subject in need thereof. A method may include administering to a subject an agent that increases the level of protein or activity of a sirtuin, such as SIRT1.

Abstract: A filter assembly including a rectangular inlet frame having a rectangular inlet opening, a rectangular outlet frame, a housing body being collapsible to have a flattened shipping state and an erect state, the collapsible housing body in the erect state being rectangular and interposed between the rectangular inlet frame and the rectangular outlet frame in an assembled state, and at least one filter having filter media installed in the rectangular inlet opening in generally sealing relation thereto and projecting from the inlet frame toward the outlet frame in the assembled state.

Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction. The invention relates to methods for treatment and prevention of cancer by administering agents that increase levels of NAD+, such as NAD+ precursors or agents involved in NAD+ biosynthesis.

Abstract: Embodiments of the invention are directed to textile fasteners. In one embodiment, the textile fastener may include a spherical member and a receiving member. The receiving member may include a flange portion and an opening within the flange portion where the opening is configured to receive the spherical member. In an embodiment, the insertion of the spherical member at least partially into the opening applies a friction force between the textile and the receiving member thereby attaching the textile fastener to the textile. In particular, magnetic interaction between the spherical member and the receiving member may maintain the friction force between the textile and the receiving member. The textile fastener also includes a cover member that substantially conceals the spherical member and the receiving member from view. The cover member may be an ornamental or functional structure, including a wearable electronic device.

Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction. The invention relates to methods for treatment and prevention of disorders associated with inflammation by administering agents that increase levels of NAD+, such as NAD+ precursors or agents involved in NAD+ biosynthesis.

Abstract: A filter assembly including a rectangular inlet frame having a rectangular inlet opening, a rectangular outlet frame, a housing body being collapsible to have a flattened shipping state and an erect state, the collapsible housing body in the erect state being rectangular and interposed between the rectangular inlet frame and the rectangular outlet frame in an assembled state, and at least one filter having filter media installed in the rectangular inlet opening in generally sealing relation thereto and projecting from the inlet frame toward the outlet frame in the assembled state.

Abstract: Disclosed herein are novel compositions and methods for the treatment of age-related diseases, mitochondrial diseases, the improvement of stress resistance, the improvement of resistance to hypoxia and the extension of life span. Also described herein are methods for the identification of agents useful in the foregoing methods. Methods and compositions are provided for the treatment of diseases or disorders associated with mitochondrial dysfunction.

Abstract: An optical probe is provided. The optical probe includes a lens extending along an axis between a first end and a second end. A spacer extends along the axis between a first end and a second end. The first end of the spacer is connected to the second end of the lens. A prism is connected to the second end of the spacer such that the prism is spaced apart from the lens by the spacer.

Abstract: A filter system includes a housing having an inlet opening surrounded by a sealing surface, an outlet opening. The housing may be rotational molded or be configured to be nestable with additional housings for shipping purposes. The system may also be configured such that the filter to be mounted therewith can be placed interior to the filter housing during shipment. A V-bank filter or a single-header box filter is positioned in the inlet opening, has a flange in general alignment with the sealing surface, and a plurality of filter media sections projecting away from the flange and into the housing interior. A seal is disposed between the flange of the V-bank or single-header box filter and sealing surface. A pre-filter, such as a panel filter, may be provided upstream from the primary filter.

Abstract: The invention relates to detection and modulation of cytochrome c acetylation. The invention has diagnostic and therapeutic applications for neurodegenerative disorders and cancer.

Abstract: A filter assembly including a rectangular inlet frame having a rectangular inlet opening to receive a primary filter and optional a prefilter. The filter assembly may include a rectangular outlet frame and a housing body that is collapsible to have a flattened shipping state and an erect state. The rectangular inlet frame may also be used as a housing by itself to support and house primary filters and prefilters. A gridwork including one or more grid dividers may be used in the rectangular inlet frame to provide 2 or more openings for receipt of filters.

Abstract: Aspects of the present invention provide machines, systems, and methods in which industrial control systems may be secured from compromise and/or disruption via authentication and firewall. In particular, an industrial controller may: randomly generate an exchange key and send the exchange key to a client device in response to a transaction request originating from the client device; combine the exchange key with a locally stored pass key to produce an authentication code; and compare a challenge key received from the client device to the authentication code to determine a match between the challenge key and the authentication code. A successful match between the challenge key and the authentication code may allow the client device to further access the industrial controller using a common industrial protocol (CIP), and a failed match between the challenge key and the authentication code may prevent the client device from further access to the industrial controller.

Abstract: Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.

Abstract: A sun screen for a vehicle having a windshield, an A-pillar and a dashboard includes a spool rotatably coupled with the dashboard and a guide moveably coupled with the A-pillar. The sun screen further includes a unitary, flexible substrate spanning a width of the windshield and having a trailing end coupled with the spool and a leading end coupled with the guide such that the substrate is selectively extendable over the windshield and retractable on the spool.

Abstract: This disclosure relates to validating data written to logical blocks on a storage subsystem adapted so that during write operations an additional sequence code is written to each logical block of data, where the sequence code remains constant for each write operation batch and where the sequence code is incremented for each new write operation batch. A sequence code verification system may comprise a data reader, a validity engine, and an error notifier. The data reader may read sequence codes from consecutive logical blocks. The validity engine may invalidate write operations in response to checking data validity by applying comparison operations to sequence codes and block offsets of batch write operations. The error notifier may notify a user of an error for each invalidated write operation batch.

Abstract: The present disclosure provides an OCT imaging system to reduce or eliminate frequency-domain aliasing artifacts. The frequency is shifted using a carrier frequency to define a sampling range substantially centered on the carrier frequency. An image of the sample is generated from a displayed imaging range that consists of a subset of the frequencies within the sampling range. Furthermore, the system may be configured to determine the carrier frequency such that a Nyquist frequency corresponding to the shifted frequency is extended beyond either an upper or a lower bound of an OCT quality envelope corresponding to the first portion of light. Additionally, the carrier frequency may be determined such that a lower bound of the OCT quality envelope is greater or less than a zero-frequency DC limit.

Abstract: A system for reducing artifacts produced in images using an optical probe system is provided. The artifacts are reduced by reducing power of secondary beam paths produced by non-Fresnel reflections by at least one of absorption, scattering and rejection of the secondary beam paths.