Abstract: An atomic interferometer and methods for measuring phase shifts in interference fringes using the same. The atomic interferometer has a laser beam traversing an ensemble of atoms along a first path and an optical components train with at least one alignment-insensitive beam routing element configured to reflect the laser beam along a second path that is anti-parallel with respect to the first laser beam path. Any excursion from parallelism of the second beam path with respect to the first is rigorously independent of variation of the first laser beam path in yaw parallel to an underlying plane.

Abstract: Compositions and methods comprising bioenergetic agents for restoring the quality of aged oocytes, enhancing oogonial stem cells or improving derivatives thereof (e.g., cytoplasm or isolated mitochondria) for use in fertility-enhancing procedures, are described.

Abstract: The disclosure provides methods, compositions, and kits for enhanced detection of microbes in samples and monitoring of antimicrobial activity in a subject.

Abstract: The disclosure provides methods, compositions, and kits for enhanced detection of microbes in samples and monitoring of antimicrobial activity in a subject.

Abstract: The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing nicotinamide mononucleotide derivatives. The invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinamide mononucleotide derivative. The invention relates to methods of using nicotinamide mononucleotide derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for treating diseases and improving cell and tissue survival.

Abstract: A filter assembly including a rectangular inlet frame having a rectangular inlet opening configured to receive a primary filter and optionally a prefilter. The filter assembly may include a rectangular outlet frame and a housing body. The rectangular inlet frame may also be used as a housing by itself to support and house primary filters and prefilters. A gridwork including one or more grid dividers may be used in the rectangular inlet frame to provide 2 or more openings for receipt of filters.

Abstract: Magnetic textile fasteners are disclosed. In one embodiment, the textile fastener may include a spherical member and two receiving members. Each of the receiving members may include a surface portion and an opening within the flat surface portion, wherein the opening is configured to receive the spherical member. In an embodiment, textiles are placed between each receiving portion and the spherical member while the spherical member is inserted at least partially into the openings. The spherical member thereby applies a force between each textile and its respective receiving member. Magnetic interaction between the spherical member and the receiving members may maintain the force between the textile and the receiving members.

Abstract: Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.

Abstract: The invention relates to compositions of nicotinamide mononucleotide derivatives and their methods of use. The invention also relates to methods of preparing nicotinamide mononucleotide derivatives. The invention relates to pharmaceutical compositions and nutritional supplements containing a nicotinamide mononucleotide derivative. The invention relates to methods of using nicotinamide mononucleotide derivatives that promote the increase of intracellular levels of nicotinamide adenine dinucleotide (NAD+) in cells and tissues for treating diseases and improving cell and tissue survival.

Abstract: A filter assembly including a rectangular inlet frame having a rectangular inlet opening, a rectangular outlet frame, a housing body being collapsible to have a flattened shipping state and an erect state, the collapsible housing body in the erect state being rectangular and interposed between the rectangular inlet frame and the rectangular outlet frame in an assembled state, and at least one filter having filter media installed in the rectangular inlet opening in generally sealing relation thereto and projecting from the inlet frame toward the outlet frame in the assembled state.

Abstract: Scattered light in the sky (sky glow) from light sources at one or more known geographic locations is used as reference point(s), from which geographic location of a system observing the sky glow is automatically ascertained. The light is scattered by particulates in the atmosphere. An upward looking camera captures an image of the sky, including the sky glow. A search engine automatically searches a catalog of modeled or pre-stored sky glows for a model that matches the image. Each model is associated with a geographic location. The models characterize each sky glow, such as in terms of color, intensity, etc., as the sky glow would appear from the associated geographic location. If a matching model is found, within a predetermined match criterion, the system outputs the geographic location associated with the matching model. Optionally, the geographic location is used to select and display a map of the geographic location.

Abstract: Silica materials having high cleaning and low abrasion properties are described, together with methods of making such materials and dentifrice compositions comprising the silica materials.

Abstract: Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.

Abstract: A sequence code verification system can be designed to include a data reader, a validity engine, and an error notifier. The data reader can read sequence codes from consecutive logical blocks. The validity engine can invalidate write operations in response to checking data validity by applying comparison operations to sequence codes and block offsets of batch write operations. The error notifier can notify a user of an error for each invalidated write operation batch. The system can validate data written to logical blocks on a storage subsystem adapted so that, during write operations, an additional sequence code is written to each logical block of data. The sequence code can remain constant for each write operation batch and the sequence code can be incremented for each new write operation batch.

Abstract: Embodiments are directed to textile fasteners. In one embodiment, the textile fastener may include a spherical member and a receiving member. The receiving member may include a flange portion and an opening within the flange portion where the opening is configured to receive the spherical member. In an embodiment, the insertion of the spherical member at least partially into the opening applies a friction force between the textile and the receiving member thereby attaching the textile fastener to the textile. In particular, magnetic interaction between the spherical member and the receiving member may maintain the friction force between the textile and the receiving member. The textile fastener also includes a cover member that substantially conceals the spherical member and the receiving member from view. The cover member may be an ornamental or functional structure, including a wearable electronic device.

Abstract: Aspects of the invention relate to methods for producing NAD precursors such as nicotinamide mononucleotide (NMN), comprising providing an isolated cell that overexpresses a nicotinamide phosphoribosyltransferase (Nampt) enzyme and culturing the cell in the presence of nicotinamide (NAM).

Abstract: The invention relates to modulation of SIRT3 activity levels. The invention has applications for regulating metabolism and mimicking caloric restriction or exercise in a muscle cell.

Abstract: This disclosure relates to validating data written to logical blocks on a storage subsystem adapted so that during write operations an additional sequence code is written to each logical block of data, where the sequence code remains constant for each write operation batch and where the sequence code is incremented for each new write operation batch. A sequence code verification system may comprise a data reader, a validity engine, and an error notifier. The data reader may read sequence codes from consecutive logical blocks. The validity engine may invalidate write operations in response to checking data validity by applying comparison operations to sequence codes and block offsets of batch write operations. The error notifier may notify a user of an error for each invalidated write operation batch.

Abstract: The disclosure provides methods, compositions, and kits for enhanced detection of microbes in samples and monitoring of antimicrobial activity in a subject.

Abstract: A sun screen for a vehicle having a windshield, an A-pillar and a dashboard includes a spool rotatably coupled with the dashboard and a guide moveably coupled with the A-pillar. The sun screen further includes a unitary, flexible substrate spanning a width of the windshield and having a trailing end coupled with the spool and a leading end coupled with the guide such that the substrate is selectively extendable over the windshield and retractable on the spool.