Patents by Inventor C. Bennett

C. Bennett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for the modulation of the expression of b7 protein
    Publication number: 20070135364
    Abstract: Anti sense oligonucleotide compositions which specifically hybridize with nucleic acids encoding B7 proteins, and use of these compositions for inhibiting expression of B7 mRNA.
    Type: Application
    Filed: May 19, 2004
    Publication date: June 14, 2007
    Inventors: C. Bennett, Timothy Vickers, James Karras, Susan Freier
  • Methods for slowing familial ALS disease progression
    Publication number: 20070117772
    Abstract: Methods for slowing disease progression in an individual suffering from familial ALS are provided. Also provided are methods of increasing the survival time of an individual suffering from familial ALS. These methods employ antisense oligonucleotides targeted to SOD1, for use in inhibiting the expression of SOD1 in the central nervous system of an individual suffering from familial ALS.
    Type: Application
    Filed: September 21, 2006
    Publication date: May 24, 2007
    Inventors: C. Bennett, Don Cleveland, Richard Smith
  • Throttle phase out control
    Patent number: 7222013
    Abstract: A vehicular powertrain has output torque established in accordance with various torque contributions in including throttle and brake torques. Throttle torque contribution is reduced proportionally to the amount of brake torque requested. Furthermore, such torque reductions are less aggressively applied with increasing throttle torques requested.
    Type: Grant
    Filed: February 14, 2004
    Date of Patent: May 22, 2007
    Assignee: General Motors Corporation
    Inventors: Tung-Ming Hsieh, Adam C. Bennett, Todd M Steinmetz
  • Method for active engine stop of a hybrid electric vehicle
    Patent number: 7217221
    Abstract: A method for providing an active engine stop of the engine of a hybrid electric vehicle. The method utilizes the electric machine to oppose and rapidly stop the rotation of the engine at a controlled rate. The method includes the calculation of an input speed reduction trajectory using the engine speed when the active engine stop request is made and a predetermined speed reduction interval. The speed reduction interval is less than a time from the active stop request to the shutoff command to the electric machine The method provides rapid deceleration of the engine, particularly through the powertrain resonance speed, reducing the amount of vibration energy dissipated through the powertrain and chassis. The method removes the electric machine torques from the engine prior to achieving zero engine speed in order to avoid imparting a negative engine speed or counter-rotation of the engine.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: May 15, 2007
    Assignee: General Motors Corporation
    Inventors: Jy-Jen F. Sah, Gregory A. Hubbard, Adam C. Bennett, Todd M. Steinmetz, Michael D. Foster
  • Method and system for discovering managed devices in a data network
    Patent number: 7216157
    Abstract: Network apparatuses, networks, computer program products, and management station operational methods are provided. One aspect of the invention provides a network apparatus including a management station adapted to couple with a network including a plurality of managed devices, the management station being configured to output a plurality of initial commands for application to respective managed devices, the initial commands being configured to stimulate initial responses from the managed devices, the management station being further configured to receive the initial responses, to identify responding ones of the managed devices responsive to the received initial responses, and to provide an asset table containing the identified managed devices.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: May 8, 2007
    Assignee: VerizonBusinessGlobalLLC
    Inventors: David Liu, David C. Bennett
  • Antisense modulation of superoxide dismutase 1, soluble expression
    Publication number: 20070054869
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of superoxide dismutase 1, soluble. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding superoxide dismutase 1, soluble. Methods of using these compounds for modulation of superoxide dismutase 1, soluble expression and for treatment of diseases associated with expression of superoxide dismutase 1, soluble are provided.
    Type: Application
    Filed: June 7, 2006
    Publication date: March 8, 2007
    Inventors: C. Bennett, Kenneth Dobie, Don Cleveland, Richard Smith
  • Antiviral oligonucleotides having a conserved G4 core sequence
    Publication number: 20070015723
    Abstract: Modified oligonucleotides having a conserved G4 sequence and a sufficient number of flanking nucleotides to significantly inhibit the activity of a virus or phospholipase A2 or to modulate the telomere length of a chromosome are provided. G4 quartet oligonucleotide structures are also provided. Methods of prophylaxis, diagnostics and therapeutics for viral-associated diseases and diseases associated with elevated levels of phospholipase A2 are also provided. Methods of modulating telomere length of a chromosome are also provided; modulation of telomere length is believed to play a role in the aging process of a cell and in control of malignant cell growth.
    Type: Application
    Filed: May 17, 2006
    Publication date: January 18, 2007
    Inventors: Ronnie Hanecak, Kevin Anderson, C. Bennett, Ming-Yi Chiang, Vickie Brown-Driver, David Ecker, Timothy Vickers, Jacqueline Wyatt
  • Antisense modulation of superoxide dismutase 1, soluble expression
    Publication number: 20060293269
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of superoxide dismutase 1, soluble. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding superoxide dismutase 1, soluble. Methods of using these compounds for modulation of superoxide dismutase 1, soluble expression and for treatment of diseases associated with expression of superoxide dismutase 1, soluble are provided.
    Type: Application
    Filed: June 7, 2006
    Publication date: December 28, 2006
    Inventors: C. Bennett, Kenneth Dobie
  • Metal matrix composite structure and method
    Patent number: 7141310
    Abstract: Compound preforms are provided having a first region, including a porous ceramic and a second region including a porous or solid ceramic in which the two regions differ in composition. The compound preform is infiltrated with a liquid metal which is then solidified to form a metal matrix composite.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: November 28, 2006
    Assignee: Ceramics Process Systems Corporation
    Inventors: Richard W. Adams, Grant C. Bennett, Kevin Fennessy, Robert A. Hay, Mark Occhionero
  • Silent operating mode for reducing emissions of a hybrid electric vehicle
    Patent number: 7127337
    Abstract: This novel silent operating mode for a hybrid electric vehicle (HEV) reduces noise and emissions compared to traditional HEV operating modes. It is a complementary series of software control functions that allows the vehicle to operate with reduced noise and emissions where specifically needed, while phasing-in engine power where allowed. The method utilizes an energy storage system budget associated with a modal quantity of energy allocated for the mode, and is adapted to automatically adjust the operation of the vehicle to accommodate deviations from the budgeted energy amount. The mode also adjusts the vehicle operation in conjunction with changes in the parametric conditions of the ESS.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: October 24, 2006
    Assignee: General Motors Corporation
    Inventors: Adam C. Bennett, William R. Cawthorne, Tung-Ming Hsieh, Gregory A. Hubbard
  • Antisense modulation of integrin beta 4 binding protein expression
    Publication number: 20060172957
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of Integrin beta 4 binding protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Integrin beta 4 binding protein. Methods of using these compounds for modulation of Integrin beta 4 binding protein expression and for treatment of diseases associated with expression of Integrin beta 4 binding protein are provided.
    Type: Application
    Filed: November 13, 2001
    Publication date: August 3, 2006
    Inventors: C. Bennett, Susan Freler
  • Antisense modulation of CD40 ligand expression
    Publication number: 20060160758
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of CD40 ligand. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CD40 ligand. Methods of using these compounds for modulation of CD40 ligand expression and for treatment of diseases associated with expression of CD40 ligand are provided.
    Type: Application
    Filed: January 20, 2005
    Publication date: July 20, 2006
    Inventors: C. Bennett, Susan Freier, Brenda Baker, Brett Monia, Nicholas Dean, Hong Zhang, Susan Murray, Lex Cowsert, Madeline Butler, Robert McKay, Donna Ward, William Gaarde, Ian Popoff, Jacqueline Wyatt, Andrew Watt
  • Stretch removable adhesive articles and methods
    Patent number: 7078582
    Abstract: Pressure sensitive adhesive articles and methods, particularly stretch removable adhesive articles that are preferably for use in adhering to skin or like delicate surfaces. Preferably, stretch removability of the article occurs as a result of the selection of a stretch removable pressure sensitive adhesive. In one embodiment of the articles and methods, the adhesive and backing delaminate upon removal. In another embodiment of the articles and methods, the backing includes a predefined tab located in a central location of the backing.
    Type: Grant
    Filed: August 21, 2001
    Date of Patent: July 18, 2006
    Assignee: 3M Innovative Properties Company
    Inventors: William L. Stebbings, Kevin D. Landgrebe, Dave J. Hastings, Wayne K. Dunshee, Albert I. Everaerts, Zhiming Zhou, Robert C. Bennett
  • Modulation of SLC26A2 expression
    Publication number: 20060154885
    Abstract: Compounds, compositions and methods are provided for modulating the expression of SLC26A2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding SLC26A2. Methods of using these compounds for modulation of SLC26A2 expression and for diagnosis and treatment of disease associated with expression of SLC26A2 are provided.
    Type: Application
    Filed: March 4, 2005
    Publication date: July 13, 2006
    Inventors: C. Bennett, Brett Monia, Nicholas Dean, Xiaoxing Xu, Sanjay Bhanot, Brenda Baker, Susan Freier, Lex Cowsert, Robert McKay, Muthiah Manoharan, F. Dorr, Jon Holmlund, Alexander Borchers, Vickie Brown-Driver, Jacqueline Wyatt, Shin Flournoy, Elizabeth Ackermann, Hong Zhang, Andrew Watt, Eric Maracusson, Scott Cooper, Erich Koller, Loren Miraglia, William Ricketts, Kenneth Dobie, Tamara Sipes
  • Use of antisense oligonucleotide libraries for identifying gene function
    Publication number: 20060099613
    Abstract: A method for identifying one or more genes involved in a phenotype of cells, tissues or organisms, comprising the steps of contacting cells, tissues or organisms which exhibit the phenotype with a library of antisense oligonucleotides and performing a primary phenotypic assay to determine which antisense oligonucleotides in the library attenuate the phenotype. These antisense oligonucleotides correspond to genes involved in the phenotype. The method may be used to identify genes involved in various disease states.
    Type: Application
    Filed: September 9, 2005
    Publication date: May 11, 2006
    Applicant: ISIS Pharmaceuticals, Inc.
    Inventors: C. Bennett, Alexander Borchers, James Karras
  • Conjugates for use in hepatocyte free uptake assays
    Publication number: 20060084094
    Abstract: The present invention provides methods of identifying oligomeric compounds, such as siRNA and double-stranded RNA compounds, having bioactivity in vivo, and kits.
    Type: Application
    Filed: September 7, 2005
    Publication date: April 20, 2006
    Applicant: ISIS Pharmaceuticals, Inc.
    Inventors: C. Bennett, Robert McKay, Brett Monia, Brenda Baker, Namir Sioufi, Richard Griffey, Balkrishen Bhat, Eric Swayze
  • Antisense modulation of MEKK4 expression
    Publication number: 20060019920
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of MEKK4. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding MEKK4. Methods of using these compounds for modulation of MEKK4 expression and for treatment of diseases associated with expression of MEKK4 are provided.
    Type: Application
    Filed: July 11, 2005
    Publication date: January 26, 2006
    Inventors: C. Bennett, Susan Freier, Brett Monia, Nicholas Dean, Hong Zhang, Robert McKay, Donna Ward, William Gaarde, Jacqueline Wyatt, Andrew Watt, Rosanne Crooke, Mark Graham, Pamela Nero, Kenneth Dobie, Alexander Borchers, Eric Marcusson, Mark Roach
  • Compositions and their uses directed to bone growth modulators
    Publication number: 20060003953
    Abstract: Disclosed herein are compounds, compositions and methods for modulating the expression of a bone growth modulator in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.
    Type: Application
    Filed: December 3, 2004
    Publication date: January 5, 2006
    Inventors: C. Bennett, Madeline Butler, Nicholas Dean, Kenneth Dobie, Joshua Finger, Ravi Jain, Robert McKay, Brett Monia, Kathleen Myers
  • Antisense modulation of p70 S6 kinase expression
    Publication number: 20050267063
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of p70 S6 kinase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding p70 S6 kinase. Methods of using these compounds for modulation of p70 S6 kinase expression and for treatment of diseases associated with expression of p70 S6 kinase are provided.
    Type: Application
    Filed: April 27, 2005
    Publication date: December 1, 2005
    Inventors: C. Bennett, Brett Monia, Susan Freier, Brenda Baker, William Gaarde, Erich Koller, Susan Murray, Andrew Watt, Jacqueline Wyatt, Pamela Nero, Mark Roach, Lex Cowsert, Kenneth Dobie
  • Antisense modulation of interleukin 12 P35 subunit expression
    Publication number: 20050261228
    Abstract: Compounds, compositions and methods are provided for modulating the expression of Interleukin 12 p35 subunit. The compositions comprise chemically modified antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Interleukin 12 p35 subunit. Methods of using these compounds for modulation of Interleukin 12 p35 subunit expression and for treatment of diseases associated with expression of Interleukin 12 p35 subunit are provided.
    Type: Application
    Filed: March 23, 2005
    Publication date: November 24, 2005
    Inventors: C. Bennett, Brenda Baker, Susan Freier, Susan Gregory, Ronnie Hanecak, Kevin Anderson, Ming-Yi Chiang, Vickie Brown-Driver, David Ecker, Timothy Vickers, Jacqueline Wyatt, Eric Marcusson, Nicholas Dean, Sanjay Bhanot, Elizabeth Ackermann, Lex Cowsert