Abstract: A low-carbon, high-purity tantalum pentoxide powder has a carbon content of no greater than 15 ppm. A preparation method for the powder includes: (1) adding a fluotantalic acid (H2TaF7) solution into a reaction kettle, controlling the temperature of the reaction kettle at 30-60° C., adding a precipitator until the pH of the reaction solution is 8-10, then stopping introducing ammonia, and aging to obtain a tantalum hydroxide slurry; (2) filtering and washing the slurry obtained in step (1), and then carrying out solid-liquid separation to obtain a tantalum hydroxide filter cake; (3) drying the filter cake obtained in step (2) to obtain white tantalum hydroxide powder; (4) calcining the tantalum hydroxide powder obtained in step (3), crushing and screening the calcined sample to obtain tantalum pentoxide powder; and (5) subjecting the tantalum pentoxide powder obtained in step (4) to heat treatment at a temperature of 1000-1500° C. to obtain the powder.

Abstract: The present disclosure provides, in part, 5-membered heteroaryl carboxamide compounds, and pharmaceutical compositions thereof, useful for disruption of HBV core protein assembly, and methods of treating Hepatitis B (HBV) infection.

Abstract: The present invention provides a sidewall system and a collapsible building using the system thereof. The sidewall system has a fixed wall, a sidewall, and a single-side eave system that has an eave panel that can be unfolded and folded along with the movement of the sidewall automatically. A collapsible building with two sidewall systems and a sliding, retractable roof is also provided. The collapsible building can create an enclosed space easily and quickly. To solve the above problems, the present invention is proposed. A multi-layered folding roof fitted with a liftable ceiling is also provided. The roof can be unfolded and retracted in the horizontal direction, and the internal multi-piece ceiling structure will unfold and fall simultaneously with the roof due to the action of the internal slide rail. The invention can be used in a variety of buildings and mobile homes.

Abstract: The present disclosure is directed to inhibitors of the CBP/p300 family of bromodomains. The compounds can be useful in the treatment of disease or disorders associated with the inhibition of the CBP/p300 family of bromodomains. For instance, the disclosure is concerned with compounds and compositions for inhibition of the CBP/p300 family of bromodomains, methods of treating, preventing, or ameliorating diseases or disorders associated with the inhibition of CBP/p300 family of bromodomains, and methods of synthesis of these compounds.

Abstract: The present invention provides a sidewall system and a collapsible building using the system thereof. The sidewall system has a fixed wall, a sidewall, and a single-side eave system that has an eave panel that can be unfolded and folded along with the movement of the sidewall automatically. A collapsible building with two sidewall systems and a sliding, retractable roof is also provided. The collapsible building can create an enclosed space easily and quickly. To solve the above problems, the present invention is proposed. A retractable roof with a foldable ceiling is provided. The roof can be used on some expandable structures such as recreational vehicles or mobile houses. Compared to the traditional sliding roof, this invention combines a foldable ceiling inside the roof. The ceiling can split the roof and room which offer a better thermal insulation function.

Abstract: Disclosed are liquid vinyl functionalized cage-type polyhedral oligomeric silsesquioxane modified by low-molecular-weight polysiloxane and a preparation method thereof. Under the catalytic action of tris(pentafluorophenyl)borane, cage-type octakis (dimethylsiloxy)-T8-silsesquioxane and hetero telechelic polydimethylsiloxane undergo a Piers-Rubinsztajn reaction, to obtain liquid Vi-POSS. Side chains of the liquid vinyl functionalized POSS in the present disclosure are Si—O—Si chain links, have better heat stability than that of common long-carbon-chain side chains, and contain vinyl functional groups capable of participating in chemical reactions, which not only have good mechanical enhancement and heat resistance properties, but also have chemical reactivity.

Abstract: A micro-displacement measurement system having a picometer scale resolution and a measurement method. The measurement system comprises a probe module, a demodulation optical path module, a static lock-in amplification module, an upper computer module, and a micro-displacement drive module. The probe module comprises a measurement FBG sensor, a matching FBG sensor, a precision stainless steel needle tube, and an external support; the demodulation optical path module comprises an ASE broadband light source, a first circulator, a second circulator, and an InGaAs photodetector; the upper computer module comprises a data acquisition card and a computer; and the micro-displacement drive module comprises a piezoelectric ceramic nano-positioner, a piezoelectric ceramic driver, a three-dimensional precision micro-motion platform.

Abstract: An electroporation system including one or more of a pipette, a pipette tip, a pipette docking assembly, and a pulse generator. The pipette docking assembly includes a pipette station, a pipette station guard, and a reservoir (e.g., a buffer tube). A method for transfecting a cell with a payload including providing an electroporation system, providing the cell, providing the payload, introducing the cell and the payload into a pipette tip, and electroporating the cell within the pipette tip by operating the electroporation system.

Abstract: Disclosed are a brake apparatus, a wheel body assembly and a rollator. The brake apparatus includes a shaft body, a housing, a magnetic induction mechanism, a rectifier mechanism and an adjustment mechanism, the housing is rotatable relative to the shaft body, the magnetic induction mechanism is used to generate resisting force opposite to a rotation direction of the housing or the shaft body by a magnetic field reaction when the housing rotating relative to the shaft body, the rectifier mechanism is used to rectify a current of the magnetic induction mechanism, the adjustment mechanism is used to adjust the magnitude of the resisting force generated by the magnetic induction mechanism. By setting the rectifier mechanism to rectify output of the multiple wires of the magnetic induction mechanism, the structure of the adjustment mechanism can be simplified, making the overall structure of the brake apparatus simpler.

Abstract: A compound including a first ligand LA of is disclosed. In the structure of Formula I, one of L1 and L2 is C, and the other is N; Y1 to Y14 are each C or N; at least two adjacent Y7, Y8, Y9, and Y10 are carbon atoms that are fused to a structure of Z1 and Z2 are each O, S, Se, NR, CRR?, or SiRR?; and each R, R?, RA, RB, RC, and RD is hydrogen or a substituent; and any two substituents may be joined or fused together to form a ring. In the compound, LA is complexed to a metal M by L1 and L2, and M has an atomic weight greater than 40. Organic light emitting devices and consumer products containing the compounds are also disclosed.

Abstract: An anti-cavitation damping composite metal structure for a flow passage component and a preparation method thereof are provided. The preparation method includes: cladding a gradient functional material layer by layer on a substrate of a flow passage component; forming periodic structures on a surface of each layer of the gradient functional material through etching by an ultrafast laser to absorb a part of an impact load energy caused by cavitation of the flow passage component, where the layers of the gradient functional material form a gradient coating with a toughness increasing layer by layer and a hardness decreasing layer by layer from bottom to top; and forming nano twins on a surface layer by a laser shock peening technique, and implanting a residual compressive stress to further improve anti-cavitation resistance of a surface.

Abstract: In aspects, the invention provides novel compositions and methods for dominant inhibition of viral infection.

Abstract: A portable hydrogen electrolyzer integrated with water purifier indicating lifetime percentage of purification materials includes an electrolysis cell, a purification chamber, and an alterable color drying tower. A purification chamber ensures that the device can use regular water, instead of deionized water, for hydrogen production. Various configurations have been contemplated using fewer parts than other devices to decrease the risk of hydrogen leakage and improve the user experience.

Abstract: The present invention provides a preparation method and use of a TNFR2 and APRIL/BAFF receptor protein fusion. Specifically, the present invention provides a fusion protein, the fusion protein comprising a TNFR2 extracellular segment and a BAFFR or BCMA or TACI extracellular segment. The fusion protein of the present invention inhibits TNF ?-induced inflammation, and also by means of combining with BAFF or APRIL, inhibits the activation of B cells, and plays a synergistic role with TNFR2, thus enhancing the effect of treating various autoimmune diseases.

Abstract: The present invention provides a single-crystal high-nickel positive electrode material and a preparation method therefor and an application thereof. The preparation method comprises the following steps: (1) mixing a precursor, a lithium source, and a nano oxide, and performing primary sintering treatment in an oxygen-containing atmosphere to obtain a primary sintered material; and (2) mixing the primary sintered material obtained in step (1) with a titanium source and a cobalt source, and performing secondary sintering treatment in an oxygen-containing atmosphere to obtain the single-crystal high-nickel positive electrode material. The present invention uses a Ti/Co co-coating method, the residual alkali amount of the prepared single-crystal high-nickel positive electrode material can be greatly reduced, and the capacity and the rate capability can also be kept at a high level, so that the technological process is reduced, and the cost is reduced.

Abstract: The present application provides anti-IGFBP7 constructs that bind to IGFBP7 (e.g., anti-IGFBP7 antibodies), nucleic acid molecules encoding an amino acid sequence of the anti-IGFBP7, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of preparing the anti-IGFBP7 construct, pharmaceutical compositions containing the anti-IGFBP7 construct, and methods of using the anti-IGFBP7 construct or compositions.

Abstract: A method is disclosed of growing an epitaxial layer on a substrate (20) of monocrystalline Silicon Carbide, SiC. The method comprises providing (S100) a source material (10) of monolithic polycrystalline SiC with a columnar micro-grain structure and the substrate (20) of monocrystalline SiC, in a chamber (5) of a crucible with a distance therein between, arranging (S102) a carbon getter (1) in said chamber (5) of the crucible close to the source material (10) and the substrate (20), said carbon getter (1) having a melting point higher than 2200° C. and an ability of forming a carbide layer with carbon species evaporated from SiC, reducing (S106) pressure in the chamber (5), inserting (S108) an inert gas into the chamber (5), raising (S110) the temperature in the chamber (5) to a growth temperature, such that a growth rate between 1 ?m/h and 1 mm/h, is achieved, and keeping (S112) the growth temperature until a growth of at least 5 ?m has been accomplished on the substrate (20).

Abstract: Provided herein are methods of treating B7-H1-expressing tumors comprising administering an effective amount of MEDI4736 or an antigen-binding fragment thereof.

Abstract: A subsurface representation of a subsurface region includes cells that define subsurface propert(ies) at different locations within the subsurface region. Initial classification of rock types within portions of the subsurface representation is obtained and used to determine probability distributions of the subsurface propert(ies) for the rock types. The probability distributions of the subsurface propert(ies) for the rock types and a spatial distribution of rock types within the subsurface representation are used in an iterative process to determine classification of rock types within the subsurface representation.

Abstract: A method of manufacturing a preform, the method including positioning at least one glass tube in a glass outer cladding to form a preform precursor, the glass tube comprising a first open end and a second open end, forming a preform from the preform precursor, and thermally treating at least one of the preform precursor and the preform. The thermally treating including sealing the first open end and the second open end of the glass tube to form a closed tube and heating and/or cooling the glass tube to manipulate gas pressure within the closed glass tube.