Abstract: Biological compositions containing animal fats and plant oils desirably are free of contaminants prior to processing into a biofuel. Disclosed herein is a method of removing such contaminants from these compositions to make that processing more efficient. The method employs a unique arrangement of mixers and centrifuges along with acidic solutions and recycle streams to remove these contaminants from the compositions.

Abstract: The present invention concerns a composition of matter comprising i) from 35 to 55% w/w of (R,Z)-3-methyl-cyclopentadec-5-en-1-one, having an ee of at least 80%; ii) from 27 to 40% of (R,E)-3-methyl-cyclopentadec-5-en-1-one, having an ee of at least 80%; iii) from 3 to 20% of (S,E)-3-methyl-cyclopentadec-4-en-1-one, having an ee of at least 80%; and iv) from 0 to 5% of (S,Z)-3-methyl-cyclopentadec-4-en-1-one, having an ee of at least 80%; as well as the use as perfuming ingredient of said composition of matter.

Abstract: The present application relates to perfume delivery systems and consumer products comprising perfume delivery systems and or perfume raw materials, as well as processes for making and using such perfume delivery systems and consumer products.

Abstract: Methods and composition are provided for recovering oil from an oil containing mixture or emulsion. The invention is particularly applicable for recovery of oil from corn in a corn to oil process. The process and compositions comprise a combination of two non-ionic surfactants i) and ii). The non-ionic surfactant i) is a non-ionic surfactant comprising a polyol derived from a sorbitol, a sorbitan, or isosorbide. The non-ionic surfactant ii) is an ester of a) polyethylene glycol and b) a fatty acid. In accordance with the methods, the combination of surfactants i) and ii) is brought into contact with a process stream mixture existing in a corn to ethanol process.

Abstract: An improved process is provided for separating corn oil from stillage comprising forming stillage from the fermentation of corn; mixing the stillage with a chemical additive comprising alkoxylated modified corn oil prepared by the transesterification of corn oil with glycerine followed by alkoxylation; and separating the corn oil from the stillage.

Abstract: The present invention relates to a method for enhancing the stability of a composition comprising the steps of adding in the composition at least a fabric conditioning compound and a cationic polysaccharide. The resulting composition has excellent stability and long storage life, as well as, superior conditioning performance.

Abstract: The present invention relates generally to methods of making surfactant compositions and detergent compositions.

Abstract: Surfactant systems and compositions incorporating the same are disclosed for use as rinse aids on plastics and other wares. The surfactant systems and compositions include both liquid and solid formulations, along with methods of use for treating plastics and other wares. The surfactant systems and compositions provide synergistic combinations allowing lower actives in composition formulations of the plastic-compatible surfactant systems providing good sheeting, wetting and drying properties.

Abstract: Surfactant systems and compositions incorporating the same are disclosed for use as rinse aids on plastics and other wares. The surfactant systems and compositions include both liquid and solid formulations, along with methods of use for treating plastics and other wares. The surfactant systems and compositions provide synergistic combinations allowing lower actives in composition formulations of the plastic-compatible surfactant systems providing good sheeting, wetting and drying properties.

Abstract: Surfactant systems and compositions incorporating the same are disclosed for use as rinse aids on plastics and other wares. The surfactant systems and compositions include both liquid and solid formulations, along with methods of use for treating plastics and other wares. The surfactant systems and compositions provide synergistic combinations allowing lower actives in composition formulations of the plastic-compatible surfactant systems providing good sheeting, wetting and drying properties.

Abstract: The present invention relates to the use of a cationic polysaccharide in a detergent composition used for treating dyed textile fibers in an aqueous medium, in order to reduce the loss of color of the dyed fibers when treating same using said detergent composition.

Abstract: Compositions including olefinic compounds are generally disclosed. In some embodiments, such compositions are cleaning compositions, and can be used to clean various surfaces and/or materials. In some embodiments, the olefinic compounds are derived from a natural oil or a natural oil derivative, for example, by catalytic olefin metathesis.

Abstract: The present invention relates to a copolymer comprising units of type A deriving from carboxylic acid monomers and units of type B deriving from sulfonic acid monomers, said units of type A and B representing more than 80 mol % of the total moles of units in the copolymer, characterized in that it comprises at least: —one first block formed of at least 95 mol % of units of type A and having a degree of polymerization DP1 comprised between 5 and 150; and —one second block formed of at least 95 mol % of units of type A and B with a molar ratio of units of type A to units of type B greater or equal to 1, wherein said units of type A and units of type B are statistically distributed, said second block having a degree of polymerization DP2 such that DP2/DP1?1. It also relates to new detergent compositions comprising such a copolymer, and to the use of this copolymer in a detergent composition, especially an ADW composition, to prevent, limit or eliminate the filming phenomena.

Abstract: The present invention relates to a an aqueous composition for removing soils from a surface to be cleaned, formed from water, a detergent mixture and a rinse aid, wherein the detergent mixture comprises a peroxidation catalyst and wherein the rinse aid comprises an oxygen source. Such a composition may provide a more effective cleaning behaviour. The present invention further relates to a method for removing soil from a surface to be cleaned comprising applying to the surface to be cleaned a composition according to the invention.

Abstract: The present invention relates generally to surfactant and detergent compositions and, more specifically, to surfactant and detergent compositions containing a propoxylated glycerine.

Abstract: A cleaning composition and process for cleaning post-chemical mechanical polishing (CMP) residue and contaminants from a microelectronic device having said residue and contaminants thereon. The cleaning compositions are substantially devoid of alkali hydroxides, alkaline earth metal hydroxides, and tetramethylammonium hydroxide. The composition achieves highly efficacious cleaning of the post-CMP residue and contaminant material from the surface of the microelectronic device without compromising the low-k dielectric material or the copper interconnect material.

Abstract: A composition for use on a hard surface. The composition has: (i) at least 7.5 wt. % of at least one surfactant selected; (ii) a blend of linear primary alcohols, or a blend of ethoxylated linear primary alcohols, wherein each alcohol of the non-ethoxylated blend or ethoxylated blend includes a carbon chain containing 9-17 carbons; (iii) a transport rate factor of less than about 55 seconds; and (iv) an adhesion time of greater than about 8 hours.

Abstract: An anchoring core for bar soap includes a planar piece with a peripheral contour having a curved area between a top face and a bottom face. The core includes depressions sunk inward of the laces, the depressions transitioning from the faces at an angle of at least ninety degrees to form a lip. Portions of the bar soap are urged into the depressions and held in place, preventing the bar soap from moving relative to the anchoring core. The depressions may be formed in predetermined patterns to constitute images, words or other preferred indicia. The depressions may also be formed as elongated channels, the elongated channels extending across the anchoring core including the curved area at the periphery so that the channels wrap around the anchoring core. The channels may be curved or form fanciful shapes and indicia as well. Additionally, the anchoring core may include multiple channels.

Abstract: The instant invention is concerned with a self-adhesive product for sanitary comprising a self-adhesive detergent unit composition shaped with a fingers grip portion, said portion being optionally covered on its external surface by a water-soluble material.

Abstract: A hair care product containing one or more hair care active agents is provided.

Abstract: The present invention relates generally to surfactant and detergent compositions and, more specifically, to surfactant and detergent compositions containing an ethoxylated glycerine.

Abstract: The invention relates to methods for producing flavour stable beverages. The methods involve reducing the level of one or more amino acids, and in particular the level of methionine. The level of amino acids may be reduced by a number of different methods, for example by increasing the level of acid or base and removal of said acid or base by Reverse Electro-Enhanced Dialysis. The level of amino acids may also be reduced by treatment with an oxidizing agent, such as H2O2. The invention also comprises combinations of such methods.

Abstract: The present invention refers to the food industry. More specifically, the present invention refers to a method for preparation of cocktails which are based on sparkling wine, such as Cava, whereby it is possible to obtain cocktails at industrial scale with an appearance of coloured pearl, and when putting the bottle in motion simulates ocean waves, which is extremely attractive for consumption, especially in night clubs and discotheques. In addition, with the method of the present invention properties of the based sparkling wine are kept in the prepared cocktail.

Abstract: The present invention refers to the food industry. More specifically, the present invention refers to a method for preparation of cocktails which are based on sparkling wine, such as Cava, whereby it is possible to obtain at industrial cocktails containing edible gold in suspension, with a visual appearance of multiple flashes, and when putting the bottle in motion it makes that the prepared cocktail acquires a particular dynamism, which is extremely attractive for consumption, specially in night clubs and discotheques. In addition, with the method of the present invention properties of the based sparkling wine in the prepared cocktail are kept.

Abstract: The present invention provides an apparatus and methods for producing tetrahydrocannabinolic acid (THCA), cannabichromenic acid (CBCA) and cannabichromenic acid (CBCA) in different ratios. The apparatus comprises:(i) a bioreactor comprising (a) an automated supply system configured to deliver a first automated supply of cannabigerolic acid (CBGA), a cannabinoid acid synthase, and a reaction mixture; and (b) a second automated system to cease the reaction; (ii) a controller configured to modify a property of the reaction mixture to produce the desired products; and (iii) an extractor configured to recover the tetrahydrocannabinolic acid (THCA), cannabichromenic acid (CBCA) or cannabidiolic acid (CBDA) and cannabichromenic acid.

Abstract: A number of novel improved microfluidic configurations and systems and methods of manufacture and operation for a microfluidic invasion assay system.

Abstract: A layered, microfluidic array is disclosed. The array comprises a first layer comprising at least one culture channel; a second layer comprising at least one microfluidic channel; and a third layer, disposed between the first layer and the second layer. The third layer comprises a filter membrane with a plurality of pores, each pore fluidly connecting the microfluidic channel to the culture channel.

Abstract: A station for culturing biological cells in a microfluidic device is provided. The station includes one or more thermally conductive mounting interfaces, each mounting interface configured for having a microfluidic device detachably mounted thereon; a thermal regulation system configured for controlling a temperature of microfluidic devices detachably mounted on the one or more mounting interfaces; and a media perfusion system configured to controllably and selectively dispense a flowable culturing media into microfluidic devices detachably mounted on the one or mounting interfaces.

Abstract: Provided herein are novel methods for expansion and passaging of cell aggregates comprising stem cells and/or differentiated cells and comprising the use of closed systems on rocking platform bioreactors. The methods of the invention permit closed system serial passage expansion of pluripotent stem cells and/or progeny thereof with associated pluripotency markers and differentiation potential.

Abstract: A culturing device includes an incubator part. The incubator part includes an internal housing, a mounting part installed within the internal housing and configured to mount thereon a container which stores cells, a plurality of heating parts installed within the internal housing and disposed in a symmetrical relationship with respect to an axis of rotational symmetry extending in an up-down direction, a gas circulation part installed in an upper central position within the internal housing and configured to draw a gas existing within the internal housing and to discharge the gas thus drawn; and a diffusion member configured to diffuse the gas discharged from the gas circulation part within the internal housing in a symmetrical relationship with respect to the axis of rotational symmetry.

Abstract: Embodiments provide methods to produce an assembly that mimics in vitro the human microenvironment of a primary tumor site, a secondary distant organ, and circulation. Methods and apparatuses that provide a platform for the isolation of primary tumor, invasive, and metastatic cells to be used for evaluation of therapeutic efficacy and diagnostics as applied to metastatic cancers are also provided.

Abstract: A cell detection device and a cell detection method is provided with which it is possible to efficiently acquire images of cells to be measured. Cell detection device comprises flow cell through which a measurement specimen that contains particles is caused to flow, particle detector for detecting the particles in the measurement specimen supplied to flow cell, particle sorter for sorting particles that satisfy a detection condition and other particles on the basis of the result of detection performed by particle detector, specimen supply part for supplying, to flow cell, an image-capture specimen that includes detection-condition-satisfying particles that have been sorted by particle sorter, and particle-image-capture part for capturing images of the particles in the sorted image-capture specimen supplied to flow cell.

Abstract: A cell magnetic sorting system comprises a continuous magnetic cell sorting apparatus. The continuous magnetic cell sorting apparatus comprises a rotating magnetic field generator, a forward solenoid and a reverse solenoid; the forward solenoid and the reverse solenoid surround the rotating magnetic field generator in forward and reverse directions, one end of the forward solenoid is connected to a cell solution source, the other end of the forward solenoid is connected to one end of the reverse solenoid through a T-shaped tube, an inlet of a T-shaped tube is connected to an outlet of the forward solenoid, a first outlet of the T-shaped tube is connected to an inlet of the reverse solenoid, a second outlet of the T-shaped tube is connected to an inlet of the target cell collection container.

Abstract: The present invention directs to a centrifugal filtration device, for separating living cells, including a spindle (28), a rotary arm (211) which is connected vertically to the spindle (28), a microporous membrane filter (31A;31B) which is mounted on the rotary arm (211), and a liquid distributor (4) arranged above the spindle (28). The microporous membrane filter (31A;31B) includes an inlet (311A;311B), an outlet (312A;312B), a front cavity (313A;313B) having the inlet (311A;311B) formed thereon, a rear cavity having the outlet (312A;312B) formed thereon, and a filter membrane (315A;315B) arranged between the front cavity and the rear cavity; the diameter of each filter pore formed in the filter membrane is smaller than that of the cell which needs to be separated. The present invention also discloses a cell separation system.

Abstract: This invention relates to an improved process for culturing bacteria of the family Streptococcaceae (such as of the genus lactococcus), a medium for culturing the bacteria, and the obtained bacteria cells.

Abstract: The invention relates to a method for the protein enrichment of a microalga of the genus Chlorella, cultivated under heterotrophic conditions. The method is characterized in that the heterotrophic cultivation comprises a step intended to slow down the growth of the microalga, with the fermentation medium being deficient in a nitrogen-free nutritional source.

Abstract: A structure used for animal cells is provided which includes an elastic body layer having a flat surface on which animal cells are left. The elastic body layer has a surface whose elasticity is changed by partially supporting the elastic body layer from the rear side or by changing a thickness of the elastic body layer.

Abstract: Provided herein are methods of reducing or eliminating undifferentiated pluripotent stem cells, where the methods comprise contacting an effective amount of a compound to a heterogeneous cell population or sample comprising or suspected of comprising differentiated cell types and undifferentiated pluripotent stem cells, whereby the contacting selectively reduces or eliminates undifferentiated pluripotent stem cells from the cell population or sample. Also provided are methods for obtaining a population of stem cell-derived cell types substantially free of undifferentiated pluripotent stem cells as well as isolated populations of such of stem cell-derived cell types.

Abstract: A method is disclosed of producing a cell population with a high target cell purity, including changing a character of contaminating cells in a cell population including target cells and the contaminating cells, and removing the contaminating cells and/or collecting the target cells based on the changed character. The disclosure also relates to a cell population with a high target cell purity, produced by the method, and a method of producing a sheet-shaped cell culture, including culturing the cell population into a sheet shape, a sheet-shaped cell culture containing the cell population, a medical composition containing an effective component selected from the group including the cell population and the sheet-shaped cell culture, and a method of treating a disease in a subject, including administering an effective amount of the cell population, the sheet-shaped cell culture or the medical composition, to the subject needing the same.

Abstract: The invention relates to microscale cell separating apparatus which are able to separate cells on the basis of size of the cells, interaction of the cells with surfaces of the apparatus, or both. The apparatus comprises a stepped or sloped separation element (16) interposed between an inlet region (20) and an outlet region (22) of a void that can be tilled with fluid. The void can be enclosed within a cover (12) and fluid flow through the void engages cells with the separation element. Only cells which have (or can deform to have) a characteristic dimension smaller than or equal to the distance between a step and the cover or body can pass onto or past a step. Modifications of surfaces within the apparatus can also inhibit passage of cells onto or past a step.

Abstract: Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising definitive endoderm cells into cells which are capable of forming tissues and/or organs that are derived from the gut tube.

Abstract: A method for stem or progenitor cell culture. More precisely, the invention relates to a method for cell culture using one or more I?I (inter-alpha trypsin inhibitor or inter-alpha inhibitor) protein(s) or part(s) thereof as a component in a cell culture media or a coating on a cell culture surface material. Furthermore the invention relates to a cell culture media and a cell culture coating/matrix provided with one or more I?I proteins(s) or part(s) thereof.

Abstract: Compositions and methods for inducing differentiation of stem cells such as cancer stem cells (CSCs), and increasing sensitivity of CSCs to at least one oxidizing agent in a subject include sulindac and/or epimers thereof. These sulindac-based compositions and methods are particularly useful for treating cancers such as glioblastoma (GBM) and for differentiating stem cells in vitro that can be used for cell replacement therapy in a subject in need thereof.

Abstract: Compositions and methods are provided for the purification of astrocytes from biological samples or from in vitro cultures. An advantage of the methods of the invention is the ability to isolate astrocytes in a quiescent state, which allows analysis of the cells in a more natural state.

Abstract: Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes IL-13 or a variant thereof that binds interleukin-13R?2 (IL13R?2), a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.

Abstract: Neutrophil extracellular traps (NETS) are webs of DNA held together with immunogenic peptides, released by neutrophils subsequent to activation. NETS are the most potent stimulator of dendritic cells, monocytes and T cells given their ability to activate TLR3, TLR4, TLR7 and TLR9. The use of NETS for in vivo stimulation of immunity in a therapeutic sense has not been utilized due to fear of anti-DNA antibody formation and subsequent development of systemic lupus erythromatosis. The current invention provides means of safely generating NETS in vitro through peripheral blood utilizing clinically safe means such as yeast-derived component zymosan, isolating said NETS, utilizing said NETS to in vitro activate cytokine production from PBMC in vitro, and concentrating said cytokines. Cytokines generated by this methodology have superior ability to stimulate NK cells in vitro as compared to isolated NK stimulatory cytokines.

Abstract: The present invention relates to novel methods of growing or otherwise producing unpassaged or minimally passaged dermal cells from a small biopsy specimen for treating skin injuries significantly larger than the biopsy.

Abstract: Media for the culture of pluripotent stem cells and differentiation of cardiomyocytes, and methods of using this media to produce cardiomyocytes. These media and methods can support cloning, differentiation and induced pluripotent stem (iPS) cell derivation.

Abstract: Described herein are compositions relating to alphavirus-based virus-like particles (VLPs) and methods for making and using the described VLPs. The described compositions include VLPs and vectors and cells used to produce the VLPs. Also included are related methods to produce the VLPs, to transduce cells using the VLPs, and to produce a protein or polynucleotide of interest in a target cell using the VLPs. Also described are alphavirus-based replicons that allow for expression of proteins or polynucleotides of interest in a target cell without a cytopathic effect.

Abstract: A modified luciferase protein which is a sensor for molecules including cAMP, cGMP, calcium, chelators thereof, kinases, or phosphatases is provided. Also provided is a circularly permuted anthozoan luciferase protein and a decapod crustacean luciferase protein, optionally containing one or more heterologous amino acid sequences, at least one of which directly or indirectly interacts with a molecule of interest. Further provided is a modified anthozoan luciferase protein and a decapod crustacean luciferase protein containing an insertion of one or more heterologous amino acid sequences, at least one of which directly or indirectly interacts with a molecule of interest.