Abstract: Provided is a system including a plurality of inhalers that each include a processor configured to determine a value of a usage parameter relating to use of the respective first inhaler, encrypt data based on the value, and transmit the encrypted data. At least two of the inhalers include different medicament, such as a rescue medicament and a maintenance medicament. The system includes an external device that includes a processor configured to distinguish between the encrypted data of each respective inhaler, determine respective usage information relating to each of the distinct types of medicament based on the respective encrypted data, and control a user interface (e.g., of the external device) to communicate the usage information related to each inhaler and/or each respective type of medicament.

Abstract: A water reservoir for use with a medical treatment apparatus includes a reservoir base including a cavity structured to hold a volume of water to humidify a supply of pressurized breathable air. The reservoir base includes a heat conductive portion, wherein the heat conductive portion is configured to thermally engage with a heating assembly of a water reservoir dock associated with the medical treatment apparatus to allow thermal transfer of heat from the heating assembly to the heat conductive portion. The water reservoir includes at least one protrusion that protrudes outwardly from a side of the reservoir base, wherein the at least one protrusion is configured to be fully inserted into at least one slot on a side of the water reservoir dock, and wherein the at least one protrusion only extends partially along the side of the reservoir base.

Abstract: The present disclosure provides a conductive component for an output electrode of an electronic cigarette. The conductive component can include a first conductive element, a second conductive element, and a seal element. The first conductive element and the second conductive element tightly clamps the seal element, and the first conductive element passes through the seal element, fixes and establishes electrical connection with the second conductive element. The unclamped part of seal element extends outwards when an extending end of the seal element is fixed the seal element partly separates the first conductive element and the second conductive element so that the first conductive element is exposed and electronically connected with the external load, whereas the second conductive element is covered by the seal element within the device and electronically connected with the internal components of the device.

Abstract: An aerosol generator has a vibratable plate with apertures therein and an annular piezo which causes movement of the vibratable plate. An annular support member supports the piezo and the vibratable plate. A first electrical power conducting pin engages directly with a first, top, surface of the piezo. A second electrical power conducting pin indirectly conducts electrical power to a second surface of the piezo, by contacting an extension tab of the support member, also on its top side. There is a film of cured epoxy adhesive on the tab, providing excellent gripping force between the pin and the support. The aerosol generator avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the same lateral and top side of the piezo and support member. The pins may have multi-point tips for particularly effective electrical contact.

Abstract: A device for delivering medication to a user may include a main body, an electronics module, and a slider. The main body may include a mouthpiece, a medication reservoir, and a mouthpiece cover, where the mouthpiece cover may be hinged to the main body. The electronics module may include a communication circuit, a pressure sensor, and a switch. The slider may be configured to engage the switch when the mouthpiece cover moves from a closed position to an open position. The switch may be configured to switch the electronics module from an off state or a sleep state to an active state. The electronics module may be configured to never return to the off state after the mouthpiece cover is moved to expose the mouthpiece for the first time by the user.

Abstract: An aerosol-generating system is provided, including: an aerosol-generating device including a power source; and a cartridge removably coupled to the aerosol-generating device, the cartridge including: a liquid storage portion including a housing having an open end and containing a liquid aerosol-forming substrate, a heater assembly at the open end of the housing and including a planar electrical heating element to heat the liquid aerosol-forming substrate to form an aerosol, and a capillary material in contact with the planar electrical heating element and being configured to convey the liquid aerosol-forming substrate to the planar electrical heating element, the liquid storage portion being at a first side of the heater assembly and an airflow channel being at a second side of the heater assembly, and the power source of the aerosol-generating device is to supply power to the heater assembly.

Abstract: Liquid drug cartridges and an associated inhaler are used to deliver one more separate doses of an aerosolized liquid drug. A cartridge includes a container for storing the liquid drug, an end cap having an ejection opening, a filter element, and a piston that is repositionable relative to the container to selectively eject a volume of liquid drug from the ejection opening. The filter element filters the liquid drug prior to ejection from the ejection opening. The liquid drug cartridge can be coupled with an inhaler that includes an aerosol generator. The aerosol generator includes a vibratable membrane onto which the liquid drug is ejected. The liquid drug is aerosolized by the vibration of the membrane for inhalation by a user.

Abstract: A nebuliser device with a vibrating mesh, for administering medicaments, includes a casing, a nozzle, a nebuliser and a chamber that houses a medicament. The chamber housing a medicament is a disposable capsule forming an independent body that can be extracted from the casing of the device. The disposable capsule includes a connector for attaching to the nebuliser and to the casing. The connector allow the disposable capsule to be coupled to the nebuliser device or uncoupled therefrom.

Abstract: The disclosure relates to a nasal cannula comprising a port configured for delivery of a medicament into a flow of a fluid being delivered by the nasal cannula to a user and/or configured for interfacing with a medicament delivery device or an instrument. The disclosure also relates to a nasal cannula comprising an asymmetric profile to reduce an amount of occlusion of one nare of a user to provide access for an instrument to the nare with the nasal cannula in use.

Abstract: Disclosed is a family of intranasal spray dispensers for administering uniform low doses of desmopressin so as to achieve safe antidiuresis in human patients. The dispensers of the invention may be used in the treatment of nocturia, primary nocturnal enuresis, incontinence, urinary frequency, diabetes insipidus, or any disease or syndrome where desmopressin therapy is useful or where safe temporary suppression of urine production may lead to beneficial health effects or increased convenience in voiding control.

Abstract: A method for controlling an electronic cigarette to take account of a malfunctioning or non-functioning airflow sensor includes sensing airflow through the electronic cigarette and generating a signal according to each airflow or inhalation. The signal causes a first time counter (first stopwatch) to begin counting and the atomizer is operable, until a preset time period has been counted. Other preset time periods can be set to begin and be counted after combinations of signals and periods have occurred, to allow user to continue using electronic cigarette in a normal manner.

Abstract: Inhalator comprising an aerosol generator configured to generate an aerosol by nebulizing a fluid and a controller configured to control operation of the aerosol generator and a housing accommodating at least the aerosol generator and the controller, the housing having a base for supporting the housing on a horizontal surface, wherein a portion of the housing accommodating at least a portion of the controller is arranged further away from the base than the aerosol generator as seen in a vertical direction, when the base is supported on the horizontal surface.

Abstract: A computer-based system for receiving, analyzing, processing, managing and sending personal health information, and other information in conjunction with use of one or more personal nebulizer or vaporizing devices and personal breath analysis devices. System devices include a personal nebulizer or vaporizing unit with a mouthpiece, which may be detachable and replaceable. The mouthpiece includes an orifice through which vapor is emitted. The substance to be vaporized is contained in an ampoule inserted into the device, where the substance enters an atomization chamber where vaporization is achieved through piezoelectric transducers or atomizers providing sonic or ultrasonic vibration. The substance includes a variety of therapeutic, homeopathic, or naturopathic formulations, remedies, or serums.

Abstract: An apparatus is disclosed, comprising a detector unit comprising a detector configured to detect an actuation action performable via the detector unit to an actuation button of a medical device to cause the medical device to eject at least a portion of a medicament comprised in the medical device. The detector is configured to detect the actuation action based on a detection of a force and/or a touch applied to the detector unit as part of the actuation action. The apparatus further comprises an electric unit connected to the detector and configured to store and/or provide information related to the detected actuation action. Furthermore, an according method and a computer program for controlling this method are disclosed.

Abstract: A respiratory system includes a nebulizer pneumatically connected to a breathing unit. A pressure sensitive mechanism detects negative pressure at the breathing unit due to inspiration and initiates nebulization. The nebulizer is configured to cease nebulization prior to the end of inspiration. Residual medicament disposed in the system is cleared from the system and delivered to the patient during the remainder of the inspiration cycle. A compressor provides positive pressure to aid delivery of medicaments to the patient.

Abstract: A nasal irrigation device communicates an irrigant to a device user and comprises a mechanics module and a reservoir assembly wherein a source of saline comprising a cartridge is disposed within the mechanics module adjacent a lid assembly for piercing the cartridge upon closing of a lid for releasing the cartridge contents into the reservoir assembly. A faux collapsible cartridge for testing operability of a nasal irrigation device comprises a housing including a shaft, a spring biased rod extending from the housing shaft, and a flange depending from a housing wall whereby the rod and flange are disposed to actuate a trigger assembly of the nasal irrigation device.

Abstract: The technology disclosed herein provides a system for generating a personal unclonable function (PUF) for a user based on a biometric data related to the user. Implementations of the system include a camera to generate a partial image of a user's tongue, a sensor to generate a moisture level in the user's saliva, a PUF generator configured to generate a PUF benchmark of the user based on combination of the partial image of a user's tongue and the moisture level in the user's saliva, and an access control unit configured to control access to one or more user devices based on the PUF benchmark.

Abstract: Compositions for treatment or prevention of viral infections, such as influenza A and B, coronaviruses, including but not limited to COVID-19 and any variant thereof, and rhinoviruses, along with related treatment methods. Certain compositions according to preferred embodiments may comprise chlorpheniramine and albuterol administered by inhalation in nebulized form.

Abstract: An inhaler housing (14) for an inhaler (10) for inhaling inhalable substances, the inhaler having: a body (14) and a dose counter (24) with a return spring (28), wherein a distinct guide surface (162) is provided for guiding the end of the return spring into a recess (152), the distinct guide surface being wider than an entrance mouth (160) of the recess, a dose counter chamber (22) being provided which is separated from a tubular interior space (182) of the inhaler by a barrier (180), the barrier including a stepped upper wall area (184) including at least three steps (186, 188, 190, 192) at different levels, the inhaler having a valve stem block (62) having an inner bore and a valve stem block having a seal (224) in the inner bore with a second diameter which is smaller than a first diameter of the inner bore, the inhaler having a canister (150) being adapted to move during operation between 1 and 4 mm, a drive being arranged to apply a firing force of between 15 N and 60 N of force to the canister at a pos

Abstract: An apparatus for humidifying a flow of breathable gas includes a water reservoir and a water reservoir dock forming a cavity structured and arranged to receive the water reservoir in an operative position. The water reservoir comprises a reservoir base including a cavity structured to hold a volume of water, the reservoir base including a main body and a thermally conductive portion provided to the main body. The thermally conductive portion comprises a combined layered arrangement including a metal plate and a thin film, the thin film comprising a non-metallic material and including a wall thickness of less than about 1 mm. The thin film is adapted to form at least a bottom interior surface of the water reservoir exposed to the volume of water, and the metal plate is adapted to form a bottom exterior surface of the water reservoir.

Abstract: A method for controlling operation of a lighting system is provided. The method includes operating the lighting system in a first mode during a time period to provide a first light output. The first output can be a blend of HINS light and non-HINS light. The method includes determining a dosage amount of HINS light provided during the time period. Furthermore, the method includes operating the lighting system in a second mode to provide a second lighting output. The second light output can be HINS light or a blend of HINS light and non-HINS light. Furthermore, spectral energy associated with HINS light in the second light output is greater than spectral energy associated with the HINS light in the first light output.

Abstract: A flow governor assembly for use with a medicinal inhaler. The assembly can include a housing that defines an air flow path; a flow governor positioned in the air flow path to govern air flow in the air flow path to a target governing volumetric flow rate; and a constriction in the air flow path. The flow governor can be configured to provide a variable, or dynamic, resistance to air flow in the air flow path as a function of air pressure drop between an inlet and an outlet of the flow governor. The constriction can be configured to provide a fixed, or static, resistance to air flow in the air flow path.

Abstract: Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO2 gas analysis sensors without the use of a calibration gas.

Abstract: The present disclosure relates to aerosol delivery devices comprising a power unit and a cartridge that is configured for engagement with the power unit. In particular, the cartridge can be configured for rotation about a longitudinal axis thereof so as to be insertable into a chamber of the power unit in a plurality of different orientations. Further, the aerosol delivery device can include processing circuitry that can be configured for detection of the cartridge orientation and execution of a control function assigned to the respective orientation.

Abstract: There is provided a mesh for use in forming droplets of liquid in a nebuliser, the mesh comprising a first portion (22) made of a first material having a plurality of holes passing therethrough; and a second portion (26) made of a second material that is in contact with the first portion (22), the second portion (26) having a corresponding plurality of holes passing therethrough, the plurality of holes in the second portion forming nozzles (28) for an outlet side of the mesh; wherein the first material has a higher density than the second material.

Abstract: A handheld device for dispensing a pharmaceutical substance has a housing in which a storage container with the pharmaceutical substance and a counter are arranged. The storage container dispenses the pharmaceutical substance by pressure actuation by a user after a specified displacement path has been traversed, and the counter carries out an action in order to rotate a counter wheel of the counter on the basis of the displacement path being traversed. The counter additionally has a drive part rotates the counter wheel, and the counter wheel is rotatably attached to a mounting part. The mounting part is formed independently of the housing, and the drive part is directly attached to the mounting part. The handheld device advantageously dispenses a pharmaceutical substance in that the action is first carried out on the counter wheel of the counter upon the pressure actuation, and the pharmaceutical substance is then dispensed.

Abstract: The present invention provides a novel method of converting AF and monitoring normal sinus rhythm using an initial IV dose of sotalol followed by oral sotalol maintenance therapy. This method provides a method of acute assessment of QTc prolongation to determine the safety of chronic oral sotalol therapy and reduces the hospitalization stay required for conversion and sotalol initiation.

Abstract: A method of treating respiratory system tissue, includes operations of generating a plume of particles of a treating solution from a nebulizer, inhaling particles of the treating solution, delaying exhalation of an inhalation having particles of the treating solution therein, and determining whether a dose of the treating solution has been delivered, wherein the treating solution is a solution of at least 40% ethyl alcohol, by volume.

Abstract: An inhalation system including a metered dose inhaler and a separate computing device. The inhaler includes a flow rate sensor for detecting an inhalation flow through the actuator housing upon patient inhalation and a transmitting unit for transmitting a signal of the at least first switch as well as of the flow rate sensor to the computing device. The computing device generates visual and/or acoustic messages independently of the signals of the at least one switch and the flow rate sensor in order to guide the patient through multiple steps. The computing device further evaluates the use of the inhaler by comparing the transmitted signals of the at least first switch and of the flow rate sensor with the visual and/or acoustic messages. The transmitting unit transmits the signals of the at least first switch and the flow rate sensor to the computing device after the use of the inhaler.

Abstract: The apparatus has an atomizer for the dispersal of a liquid and has an enclosed removable cartridge assembly with a reservoir of liquid and a wick with one end in communication with the liquid and a vibrating transducer in contact with another end of the wick; the transducer, wick and cartridge of liquid are arranged to allow a capillary volume of liquid from the wick to vibrate together to disperse the liquid in a direction away from the wick.

Abstract: A nebulizer with orientation independent operation is provided. The nebulizer includes an outer tube, an inner tube provided in the outer tube, and a mesh structure disposed above an end of the outer tube. A first channel, a main channel, and a second channel are formed between the outer tube and the inner tube. When in use, capillary force is created in the main channel, such that a liquid contained in the inner tube can be transported sequentially through the second channel, the main channel, and the first channel to the mesh structure. The liquid is nebulized and dispersed into the air through vibrations of the mesh structure actuated by an annular vibration source.

Abstract: A dry powder inhaler (1) for pulmonary or nasal use, employing capsules (6) containing a dose of powder for inhalation, comprising four components: a capsule tray (2), a cover (4) and a mouthpiece (8) and an inhaler body (3). Air is drawn by the patient via the mouthpiece (8) which is in communication with the capsule (6) and travels via air paths through the device (1) and through the capsule (6) thereby dispersing and entraining the dose of powder. The capsule (6) is cut by cutting means (18, 19) located on the body (3). The inhaler body (3), the mouthpiece (8) and the cover (4) are provided with hinge segments (20, 35, 42) which when assembled together and the mouthpiece (8) is locked into the body (3), form a single hinge (5) and which allows the cover (4) to freely pivot around the body (3) and the mouthpiece (8).

Abstract: A mesh nebulizer that nebulizes and ejects a medicinal liquid through a mesh portion, includes a main body including a vibration portion including a vibration surface, and a medicinal liquid pack to be detachably mounted on the main body. The medicinal liquid pack includes a lid in which the mesh portion is provided, and a medicinal liquid container that includes a recessed portion that is open toward the mesh portion and is covered by the lid, the medicinal liquid being contained in the recessed portion. At least a portion of a bottom surface of the recessed portion of the medicinal liquid container that is to oppose the vibration surface is made of a stretchable material. When the medicinal liquid pack is mounted on the main body, the stretchable material of the bottom surface stretches, allowing the vibration surface to approach the mesh portion of the lid.

Abstract: There is described an aerosol-forming substrate for use in combination with an inductive heating device. The aerosol-forming substrate comprises a solid material which is capable of releasing volatile compounds that can form an aerosol upon heating of the aerosol-forming substrate and at least a first susceptor material for heating the aerosol-forming substrate. The at least first susceptor material is arranged in thermal proximity of the solid material. The aerosol-forming substrate further comprises at least a second susceptor material which has a second Curie-temperature which is lower than a first Curie-temperature of the first susceptor material. The second Curie-temperature of the second susceptor material corresponds to a predefined maximum heating temperature of the first susceptor material. There is also described an aerosol-delivery system.

Abstract: A user interface, such as a visual user interface, is configured to display a static or motion image around an aerosol-generating device (10). The aerosol-generating device includes a housing having a curved outer surface surrounding a longitudinal axis and a flexible display (20) having a curved viewing surface at least partially surrounding the longitudinal axis disposed adjacent to the curved outer surface. A control circuit (54) is operatively coupled to the flexible display and includes a memory to store a motion image (30). The control circuit is configured to display the motion image on the curved viewing surface in response to activation of the aerosolizer, which may be executed according to a method, which may be stored on a non-transitory computer readable storage medium. A remote user device may be used with the aerosol-generating device.

Abstract: To provide an inhaler cartridge and an inhaler including a novel structure. Provided is a cartridge for an inhaler with a tank capable of containing a liquid. The cartridge includes a cap configured to seal at least part of a space in the tank. The cap includes a seal region configured to seal at least part of the space in the tank, and a reception portion that receives a conductor constituting part of an electric path between a heater for heating the liquid and the battery portion. The reception portion is provided on an outer side of the seal region.

Abstract: A nebulizer device includes an air intake port positioned downstream of a nebulizer element, and a mouthpiece positioned upstream of the nebulizer element. A flow sensor is coupled to a controller. The controller is configured to integrate an inhaled air flow signal received from the flow sensor for determining an inhaled air volume. The controller is also configured to turn on the nebulizer element when the inhaled air volume reaches a first predetermined threshold, and turn off the nebulizer element when the inhaled air volume reaches a second predetermined threshold. A method for targeted delivery of aerosolized particles to the lungs is also disclosed.

Abstract: Irrigation and/or aspiration devices and methods may be configured to aspirate and irrigate alone, sequentially, or concurrently. The devices and methods may provide a base with a removable head, and adapted for partial or complete separation of the irrigation and aspiration functions. The devices and methods can be configured to aspirate and/or irrigate the nasal and sinus cavities. The devices and methods may be manually and/or automatically controlled. The devices and methods may include removable, and/or replaceable, and/or refillable, and easily cleanable reservoirs for aspirant and irrigant. The device head and/or aspirant reservoir may comprise a diagnostic device, i.e., test device and/or container after use of the devices and methods.

Abstract: A control body is coupled or coupleable with a cartridge that is equipped with a heating element and contains an aerosol precursor composition, the control body and cartridge forming an aerosol delivery device. The control body includes a control to control the heating element to activate and vaporize components of the aerosol precursor composition. The proximity sensor detects a presence of an object nearby the control body without requiring any physical contact with the object. And the proximity sensor or control component controls operation of at least one functional element of the aerosol delivery device in response to the presence of the object so detected. In another aspect, a cartridge may include a proximity sensor to detect a level of the aerosol precursor composition, and operation of functional element(s) may be controlled in response to the level of the aerosol precursor composition so detected.

Abstract: Breath-actuated nebulizers for delivering medicine are provided, including an outlet port; an opening; and a medicine cup coupled to the opening through a venturi tube. The medicine cup receives a medicine to be delivered through the outlet port, and is coupled to the outlet port. Some embodiments include a jet nozzle coupled to a pressurized gas source and protruding into the medicine cup, and a sleeve in the medicine cup fluidically coupling the venturi tube to the medicine cup and forming a capillary volume with the jet nozzle. In some embodiments, a rib supports a diverter disposed above a nozzle tip to form a radial flow of the pressurized gas away from a nozzle axis. Also provided is a method for manufacturing and using the above nebulizer.

Abstract: A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 ?m, so as to target the pulmonary system of the user.

Abstract: A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 ?m, so as to target the pulmonary system of the user.

Abstract: A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 ?m, so as to target the pulmonary system of the user.

Abstract: A droplet delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device includes a housing, a reservoir, and ejector mechanism, and at least one differential pressure sensor. The droplet delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a stream of droplets having an average ejected droplet diameter within the respirable size range, e.g, less than about 5 ?m, so as to target the pulmonary system of the user.

Abstract: Aspects of the invention include a device for fluid delivery to the ocular surface having a self-alignment system. The fluid delivery device includes a fluid package having a reservoir and one or more apertures, an actuator component configured to eject fluid from the reservoir through the one or more apertures and an image-based self-alignment system configured to align fluid ejected through the one or more apertures with a target location on the eye of a user. Also provided are methods of using the devices in fluid delivery applications, as well as a kit that includes components of the devices.

Abstract: A user-replaceable e-liquid reservoir for dispensing e-liquid, the reservoir being inserted into, or otherwise attached to, a portable, personal e-cigarette device and engaging with an electrical or electronic pump fluid transfer system in the device, the device including: an electrical or electronic pump, being configured to transfer e-liquid from the e-liquid reservoir to an atomizing unit in the device, the pump delivering a pre-defined or variable quantity of e-liquid from the reservoir; and in which the reservoir is not user-refillable.

Abstract: A cushion member (10) for a mask structured to be worn on a face of a user. The cushion member includes a cushion portion (12) having a sealing portion (13) and a body portion (14) extending from the sealing portion, the sealing portion being structured to engage the face of the user; and at least one mesh member (22) embedded in at least one of the sealing portion and the body portion.

Abstract: An aerosol-generating system is provided, including an aerosol-generating article and an aerosol-generating device. The aerosol-generating article includes a first compartment having a first one of a volatile delivery enhancing compound source and a medicament source; and a second compartment having a second one of the volatile delivery enhancing compound source and the medicament source. The aerosol-generating device includes a cavity configured to receive the first compartment and the second compartment; and an external heater positioned about a perimeter of the cavity. The aerosol-generating device is configured to heat the first compartment and the second compartment so that the first compartment has a lower temperature than the second compartment.

Abstract: An atomizing nozzle structured particularly for nasal therapy. Preferred embodiments include a 2-piece atomizing nozzle structured to couple with luer-locking structure carried by a syringe. Such an atomizing nozzle includes a nasal stopper and a stem. A preferred nasal stopper includes a distal tip sized for insertion into a nostril of a human child, with a proximal shield portion being structured to resist over-insertion of a discharge orifice into the nostril. A nasal stopper desirably provides a centering function to urge the discharge orifice away from a nasal wall. One operable stem is structured to couple with the stopper and desirably carries unitary thread structure at a proximal end. A second operable stem is structured as a unitary part of the nasal stopper and also desirably carries unitary thread structure at a proximal end. Certain embodiments may also include spacer structure configured to reduce a dead volume inside the atomizing nozzle.

Abstract: Provided herein is a delivery device and vaporizable formulations that provide users or patients with the ability to safely, reliably, and conveniently obtain a high-quality, therapeutic vapor comprising an ayahuasca-like substance. The delivery device includes a chamber coupled to a power unit capable of providing power to vaporize the formulations for consumption of the substance in a consistently desirable and safe manner. Further included are kits and methods of treating psychological disorders using the delivery device and vaporizable formulations provided herein.