Abstract: The present invention relates to a feedback for inhalation. In order to further improve feedback and instructions to further support the correct use of an inhaler, a feedback apparatus (10) for inhalation is provided that comprises an inhaler interface (11), a processor (14), a feedback device (16), and a feature assigner (13). The inhaler interface is configured to temporarily attach the feedback apparatus to an inhalation apparatus. The feedback device is configured to provide a feedback to the user to aid in inhalation with the inhalation apparatus. The feature assigner is configured to identify a type of a predetermined feature of the attached inhalation apparatus, and the feedback device is configured to provide the feedback in dependency of the identified type of feature to instruct the user to adjust inhalation maneuver adapted to the attached inhalation apparatus.

Abstract: A spraying device for producing a spray of particles in a carrier gas at ambient pressure, includes a storage volume for a liquid substance; at least one nozzle having an inlet and an outlet, the nozzle inlet fluidly communicating with the storage volume; a counter electrode; an electric supply coupled between the at least one nozzle and counter electrode for providing a first potential and create a first electric field between the nozzle outlet and the counter electrode. The device further includes at least one discharge electrode coupled to the electric supply for providing a second potential between the discharge electrode and the counter electrode, the polarity of the second potential being opposite to the polarity of the first potential. The at least one nozzle and the at least one discharge electrode are arranged adjacent and parallel to each other and facing the counter electrode from a substantially same direction.

Abstract: An e-cigarette vaporizer device filling system and method. The system and method is particularly adapted for filling sealed vaporizer devices by use of a needle, such as a hypodermic needle, and facilitates separation of the needle from the device after filling.

Abstract: A cover for a medicine container is provided. The cover contains a deactivating material within it which can, upon release into a medicine container, deactivate and/or destroy a medicine within the container. The cover may have an automated release mechanism which controls release of the deactivating material into the medicine container.

Abstract: An inhalant dispensing system is provided, comprising an inhalant delivery apparatus having a main body, a lower body coupled to the main body and comprising a mouthpiece, and an inhalant delivery mechanism disposed within the main body and configured to deliver an aerosolized solution to the mouthpiece for user inhalation; and a lock out system configured to selectively prevent delivery of the aerosolized solution to the mouthpiece. The inhalant delivery apparatus may be assembled by inserting a portion of the inhalant delivery mechanism into the main body. The lower body may be rotatably coupled to the main body and moveable between a dispensing position and a storage position. The system may be used to control and monitor dosages of a solution contained within a smart canister and administered from the canister via an inhaler, to prevent accidental or unwanted usage of the canister and/or over-dosing.

Abstract: Disclosed are an ultrasonic electronic cigarette atomization core and atomizer, the electronic cigarette atomization core including an atomization core fixing sleeve. A first atomization sheet, a first tobacco tar guide component and a bracket are arranged in the atomization core fixing sleeve. The ultrasonic electronic cigarette atomization core not only can atomize two kinds of tobacco tar at the same time, but also can atomize the solid tobacco product, and the amount of smoke is large, therefore the demands of smokers for different tastes, in particular the demands for the taste of true cigarette, can be satisfied.

Abstract: A method of delivering a medication or a pharmaceutical product to a patient includes operations of activating an active mesh of an active mesh nebulizer, the active mesh being in contact with a liquid formulation of the medication, and configured to generate a plume of particles having a particle diameter between 1 and 6 micrometers, directing the plume of particles to a mouth of a patient during an inhalation by a patient; and stopping the plume of particles during the inhalation by the patient such that a substantial majority, or nearly all, of the plume of particles is inhaled by the patient.

Abstract: An infiltration detecting apparatus includes an infiltration detecting assembly and a controller. At least a part of the infiltration detecting assembly is attached or adjacent to a liquid guide, or is inserted into the liquid guide. The infiltration detecting assembly is configured to detect a related physical quantity X, and feed back the related quantity X to the controller. The controller is configured to calculate a degree of infiltration Q according to a data as to a relationship between Q and X, and compare values of Q and a first threshold value Q1. If Q<Q1, a heater is controlled not to heat. If Q?Q1, the heater is controlled to heat. The switch shuts off or opens the electrical connection between a power module and a heater. An electronic cigarette which includes the infiltration detecting apparatus is also disclosed, together with a method of controlling an electronic cigarette.

Abstract: A rapid chemical delivery system is presented. The system includes a portable handheld chemical storage receiving receptacle, wherein the receptacle is configured to receive and mate with an insertable chemical container and wherein the container houses a chemical. The system also includes a base affixed to the chemical storage receptacle, wherein a side of the base is configured to connect with an object and another opposing side is configured to attach to the chemical storage receptacle. The system further includes a rapid chemical deployment mechanism utilizing the portable handheld chemical storage receptacle and arranged to deploy the chemical from the chemical container when activated.

Abstract: A sensor device is removably attachable to a drug delivery device. The sensor device comprises an array of optical sensors arranged within the sensor device such that, when the sensor device is attached to the drug delivery device, which has a first movable element configured to move along a path parallel to the longitudinal axis of the drug delivery device, each optical sensor is operable to detect light received at different locations along the path and to output a signal indicative of an amount of detected light. Circuitry is configured to receive the signals output from the optical sensors and, based on the received signals, determine information associated with a location along the path of the first movable element.

Abstract: An accessory device for delivering medications from press and breath metered-dose inhalers (pMDIs), including those medications containing hydrofluoroalkane propellants. The device includes a collapsible flexible bag to which is attached a bidirectional mouthpiece and an adaptor that receives the press and breath MDI. The mouthpiece contains a reed that functions as an audible signal, and a screen to prevent inhalation of unwanted particles. The adaptor positions the press and breath MDI at an angle to direct the aerosol spray toward the center of the collapsible flexible bag. When the press and breath MDI is triggered, it discharges the aerosolized medication into the center of the collapsible flexible bag which is then inhaled by the user through the mouthpiece. This collapses the bag. The reed emits an audible sound if the user inhales above a pre-determined flow rate to maximize medication delivery and ensure dose-to-dose consistency.

Abstract: A medication dispenser includes a base seat, a circuitry unit and an outer casing. The base seat includes a mouthpiece. The circuitry unit includes a first circuit board, a battery, and first and second switches disposed on the first circuit board. The outer casing is movable relative to the base seat between a close position where the outer casing covers the mouthpiece and where the first switch is actuated such that electric power is prevented from being supplied from the battery to the first circuit board, and an open position where the outer casing uncovers the mouthpiece and where the second switch is actuated such that electric power is supplied from the battery to the first circuit board.

Abstract: A refill assembly (129) for use in a medicinal inhaler (100). The refill assembly includes a patient port (110), and an adapter (118) configured to cause a dose of medicament to be released. The adapter is movable between a first position in which a dose of medicament is not released and a second position in which a dose of medicament is released. The refill assembly further includes a lockout member (117) movable between (i) a first (locked) position in which the adapter is not movable from its first position to its second position, and (ii) a second (unlocked) position in which the adapter is movable from its first position to its second position.

Abstract: A system for reducing airway obstructions of a patient may include a ventilator, a control unit, a gas delivery circuit with a proximal end in fluid communication with the ventilator and a distal end in fluid communication with a nasal interface, and a nasal interface. The nasal interface may include at least one jet nozzle, and at least one spontaneous respiration sensor in communication with the control unit for detecting a respiration effort pattern and a need for supporting airway patency. The system may be open to ambient. The control unit may determine more than one gas output velocities. The more than one gas output velocities may be synchronized with different parts of a spontaneous breath effort cycle, and a gas output velocity may be determined by a need for supporting airway patency.

Abstract: The present invention provides a single-use, pre-packaged, sealed container (1) for use with a nebulizer device having an aerosol generator comprising a membrane, the container containing a cleaning liquid (3) and being configured to fit onto the nebulizer device, so that the container is held in place on the nebulizer device and the membrane is immersed in the liquid. The invention also provides a strip comprising a plurality of containers (10), wherein each container is detachable from the rest of the strip; a pack comprising a multi-day supply of a drug and containers; and a method for cleaning the membrane of a nebulizer device using the container.

Abstract: A cosmetic device with an exchangeable application head and a device body, wherein the device body contains a motor and drive mechanism, an actuating switch, a power supply, a head recognition element and a control element adapted to control the motor and drive mechanism based on an actuation of the actuation switch and the application head recognized by the head recognition element. It is provided that the head recognition element comprises at least one mechanical switch disposed on a carrier fixed at the device body. Further, a flexible actuation area is disposed in front of the at least one mechanical switch. The exchangeable application head has at least one recognition generating protrusion actuating through the flexible actuation area on one of the at least one mechanical switches when the exchangeable application head is mounted at the device body.

Abstract: Disclosed is a portable automatic electronic drop administration device and method of operation thereof. The device comprises a microcontroller communicatively coupled to at least an accelerometer and an electromechanical assembly to administer one or more drops of a liquid, semi-liquid or gaseous substance from any flexible container held within. The device detects whether it is in a suitable orientation before automatically self actuating the electromechanical assembly to administer one or more drops. It can be used in a variety of settings including self administration of eye drops, dispensing condiments or precise metering of liquid medications. Additionally, the device may contain sensors and wireless components to track usage and event data that may be communicated to a physician or other healthcare provider remotely.

Abstract: An electronic cigarette has a base part and a cartridge configured to be assembled thereto. The base part includes a battery and at least one heating element connected to the battery. The cartridge includes: a substance chamber configured for containing therein a substance to be smoked, wherein the substance chamber has a substance outlet; a vaporization chamber in communication with the substance outlet for receiving the substance therein; and at least one heat transfer unit configured, at least when the cartridge is assembled to the base part, for being heated by the heating element of the base part and for heating the substance provided via the substance outlet.

Abstract: A vaporization device includes a housing, a fluid pathway extending through the housing, a heating chamber with a heating element proximate a first housing end, a control circuit and a battery disposed within the housing. The heating chamber is in fluid communication with the fluid pathway. The first chamber end is open and the second chamber end includes a closed end with one or more vents. The heating element is operable to generate heat at a predetermined vaporization temperature. The control circuit has a switch operable to control a flow of current from the battery to the heating element. In use, the predetermined vaporization temperature is sufficient to vaporize phyto material in contact with the heat at the predetermined vaporization temperature to emit a vapor. Inhaling from the second housing end draws mixed vapor and air through the fluid pathway.

Abstract: A usage recording smart label and inhaler, and methods for detecting, verifying and recording actuation events of the inhaler, are disclosed. The usage recording smart label comprises a capacitive touch sensing plate to detect the presence of an activating body organ such as a hand or finger. The smart label, which may be in the form of a sticker or sticker-like, is attached to a grasping or actuation surface of the inhaler. The smart label may comprise text printed thereon, used as a replacement for an existing printed label. A usage recording method comprises (a) the usage recording smart label detecting an event of proximity of a finger for a given minimal time duration; (b) recording a timestamp of the event in memory of the smart label; (c) communicating stored timestamp data from the memory to an external device; the external device can be configured to display the actuation history.

Abstract: A pharmaceutical dispenser with a housing, a medium reservoir, a discharge opening, connection channel connecting the medium reservoir to the discharge opening, and a detection device arranged in the area of the connection channel and designed to detect medium flowing therein. The connection channel is connected to and communicates with a pressure chamber, the detection device includes a membrane which delimits the pressure chamber, and includes an electrically conductive connection portion and is subjected to pressure. The detection device has an electrical mating contact surface in relation to which a membrane-side connection portion is movable when subjected to pressure, such that an electrical contact between the conductive connection portion and the mating contact surface is established or cancelled.

Abstract: An electronic cigarette or vaporizer may include a shell and a cartomizer receivable within a chamber within a portion of the shell. A basin may be included in the cartomizer to hold a vaporizable fluid, dry substance, or other vaporizable substance such as a wax. A heating element may be provided within the basin which may have a flexible non-conductive material and a flexible conductive material.

Abstract: A delivery device for and method of modulating a condition relating to sodal cognition and/or behaviour in a human subject using oxytocin, non-peptide agonists thereof and/or antagonists thereof, comprising: providing a nosepiece to a first nasal cavity of the subject; and providing a supply unit for administering less than 24 IU of oxytocin, non-peptide agonists thereof and/or antagonists thereof through the nosepiece to an upper region posterior of the nasal valve which is innervated by the trigeminal nerve.

Abstract: A respiratory therapy device that is adapted to matingly connect with two standardized respiratory devices simultaneously to allow for combination, enhanced, single device, respiratory treatments. It monitors the number of PEP treatment events utilizing a motion sensor, and presents a resettable, visual stimulus for each event as well as providing a record of the events in each therapy cycle.

Abstract: An electronic cigarette comprises nicotine without harmful tar. The cigarette includes a shell, a cell, nicotine solution, control circuit, and an electro-thermal vaporization nozzle installed in the air suction end of the shell. The advantages of the present invention are smoking without tar, reducing the risk of cancer, the user still gets a smoking experience, the cigarette is not lit, and there is no fire danger.

Abstract: A respiratory treatment device comprising at least one chamber, a chamber inlet configured to receive exhaled air into the at least one chamber, at least one chamber outlet configured to permit exhaled air to exit the at least one chamber, and an exhalation flow path defined between the chamber inlet and the at least one chamber outlet. A restrictor member positioned in the exhalation flow path is moveable between a closed position, where a flow of exhaled air along the exhalation flow path is restricted, and an open position, where the flow of exhaled air along the exhalation flow path is less restricted. A vane in fluid communication with the exhalation flow path is operatively connected to the restrictor member and is configured to reciprocate between a first position and a second position in response to the flow of exhaled air along the exhalation flow path.

Abstract: Disclosed are an ultrasonic atomization piece, an electronic cigarette atomization core and an electronic cigarette atomizer. The ultrasonic atomization piece includes a piezoelectric ceramic main body; one surface of the piezoelectric ceramic main body is in contact with a positive electrode conducting layer, and the other surface of the piezoelectric ceramic main body is in contact with a negative electrode conducting layer, the negative electrode conducting layer extends to the surface of the piezoelectric ceramic main body on which the positive electrode conducting layer is located along a side edge of the piezoelectric ceramic main body, and a plurality of convex point areas, which cover the edge of the positive electrode conducting layer are provided on an edge of the negative conductive layer.

Abstract: A side-by-side cartridge assembly for dispensing a first fluid and a second fluid includes a first cartridge body and a second cartridge body having first and second cartridge coupling elements, respectively. The first cartridge body extends along an axial direction and has a radial boundary or periphery transverse to the axial direction. The first cartridge has a first neck portion of a neck, and the second cartridge has a second neck portion of the neck. The first neck portion projects from the first cartridge body such that the first neck portion is within the radial boundary or periphery of the first cartridge. As such, the first cartridge coupling element operatively connects to the second cartridge coupling element to secure the first cartridge to the second cartridge and form the neck for discharging a first fluid and a second fluid.

Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.

Abstract: A vaporization device assembly includes a battery, a first dampening spacer, a second dampening spacer, a printed circuit board, a vibrator, a microprocessor, a coil holder, a vaporization chamber, multiple wicks, a tank with a reservoir, a reservoir plug, and a pressure sensor in pneumatic communication with the reservoir of the tank. During operation, the vaporization device assembly notifies a user of timing related to inhalation of a vaporizable sub stance.

Abstract: Various embodiments include an inhaler for oral delivery of medication that includes an actuation detector configured to provide an actuation signal in response to release of the medication from the inhaler, and an accelerometer configured to measure an orientation of the inhaler. The inhaler may include a processor, coupled to the actuation detector and the accelerometer, configured with processor-executable instructions to perform operations to determine a quality of use of the inhaler based on the actuation signal provided by the actuation detector and the orientation of the inhaler measured by the accelerometer.

Abstract: Described herein are syringe devices comprising a syringe including a therapeutic dose of at least one drug to be used in a drug or substance overdose. Also provided herein are compositions and methods of treating opioid overdose using high dose naloxone.

Abstract: A nebulizer comprises a controller linked at its output to a nebulizer head, and at its input to a USB cable and USB plug for connection to a host system. The link between the USB plug and the controller is a USB cable with power and data channels. The controller comprises a boost circuit, a microcontroller 11, and a drive circuit. The latter provides power and control signals via a cable and proprietary plug to the nebulizer head. These signals provide power and control for a vibrating membrane receiving a liquid to be aerosolised. The controller has a housing with LED status lamps, and an ON/OFF button. The controller can be controlled via a host, either locally or remotely.

Abstract: An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes. A controller couples to the aerosol generator, the pump, and the breath sensor. In operation, the controller receives the signal from the breath sensor, controls a flow of fluid to the aerosol generator in response to the signal, and controls the aerosol generator to start aerosolizing the fluid before the patient inhales.

Abstract: There is provided an aerosol-generating system including an aerosol-generating device in cooperation with an aerosol-generating article. The aerosol-generating article includes a first compartment including a volatile liquid; and a second compartment including a delivery enhancing compound. The aerosol-generating device includes an outer housing configured to receive the aerosol-generating article; a power supply; a heater, configured to receive power from the power supply and arranged to heat the first compartment when the aerosol-generating article is received in the outer housing; an input, configured to receive an input from a user; and a controller, configured to control an amount of power supplied to the heater in dependence on a user input, such that a quantity of volatile liquid aerosolised is determined by the user input.

Abstract: The present invention is directed to improved systems, devices, and methods for delivery of a cryogen to the skin of a patient for skin treatment. A cryospray device configured to deliver a cryogen to a patient's skin can include an applicator, a supply channel, and a nozzle assembly. The applicator can include a head portion, and the supply channel can extend through at least a portion of the head portion. The nozzle assembly can be coupled to the head portion and can be fluidly coupled to the supply channel. The nozzle assembly can include a linear array of orifices that are configured to direct a planar spray of the cryogen to cool an area of a skin tissue of the patient in a linear cooling treatment.

Abstract: An apparatus such as a fluid mixer, suitable for use with a respirator, including a venturi nozzle for flow of a pressure-controlled fluid; an ambient fluid aperture in fluid communication with the venturi nozzle; a fluid port; a pressure force multiplier in fluid communication with the fluid port; and a valve moveable relative to the venturi nozzle between a start flow position and a stop flow position; where the pressure force multiplier is configured such that fluid forced into the fluid port actuates the valve relative to the venturi nozzle; and where the pressure force multiplier is configured such that fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle.

Abstract: A spacer device for use with a metered dose inhaler (MDI). The spacer device comprises an aerosol chamber for holding the aerosolized medication sprayed from the MDI. According to one particular design, the aerosol chamber has a forward shell, a rear shell, and an extendable barrel in between. The extendable barrel comprises a flexible plastic sheath that is supported by a coiled wire spring. The spacer device further comprises a mounting bracket to hold the MDI. The mounting bracket holds the MDI such that the spray outlet of the MDI is mated with the aerosol chamber. Also, the assembly is configured such that the aerosol chamber is aligned substantially parallel to the actuator boot of the MDI. During use, the aerosol chamber is folded downward away from the MDI. The aerosol chamber is then extended outward to increase its volume.

Abstract: In an example, an apparatus includes a container to hold a quantity of a consumable resource. A mechanical drive coupling is attached to the container. The mechanical drive coupling includes a bore and a locking mechanism integrated into the bore. The locking mechanism locks the container to a drive mechanism when the bore and the drive mechanism are rotatably engaged.

Abstract: The present embodiments provide apparatus and methods suitable for delivering a therapeutic agent to a target site. The apparatus generally comprises at least one container for holding a therapeutic agent, and a pressure source for facilitating delivery of the therapeutic agent. In one embodiment, the pressure source may be placed in selective fluid communication with a proximal region of the container and fluid from the pressure source may flow through at least a portion of the container to urge the therapeutic agent through container towards the target site. In an alternative embodiment, the container and the pressure source may be coupled to first and second inlet ports of a connecting member, respectively, such that the therapeutic agent flows through an outlet port of the connecting member and towards the target site.

Abstract: Adherence monitors are disclosed, incorporating cap removal sensors together with a determined time period in order to determine that a dose of medicament has been dispensed. In another form, cap removal data is combined with acoustic data to determine that a dose of medicament has been dispensed. Several specific structural arrangements are also disclosed.

Abstract: At least one example embodiment provides a non-combustible smoking system or kit, comprising: a cartridge having a first end and a second end; and a tobacco containing section having a third end and a fourth end. The cartridge includes: a pre-vapor formulation reservoir element and a pre-vapor heating element coupled to the pre-vapor formulation reservoir element. The tobacco containing section includes a tobacco housing and a tobacco heating element. The first end of the cartridge is configured to be connected to the fourth end of the tobacco containing section, and the second end of the cartridge is configured to be connected to the third end of the tobacco containing section.

Abstract: A surface acoustic wave electronic cigarette system includes a piezoelectric substrate, a liquid guiding cavity, an atomization cavity, and a power feeder port. The liquid guiding cavity and the atomization cavity are provided on an upper surface of the piezoelectric substrate. An isolation board is provided between the liquid guiding cavity and the atomization cavity. The power feeder port is provided on an outer side surface of the piezoelectric substrate. The surface acoustic wave electronic cigarette of the present disclosure generates an aerosol with a smaller particle diameter by atomization, which has a comfortable smoking experience and a pure and subtle fragrance.

Abstract: There is described a handheld aerosol-generating device which comprises an elongate tubular component having an axial length and which accommodates an electric power source. A mouthpiece portion having at least one air inlet and an outlet communicating with one another is detachably connected with the elongate tubular component. The electric power source is of an annular configuration extending at least about a major part of the axial length of the tubular component, and encloses an elongate receptacle which is open towards the mouthpiece portion, for accommodation of a cartridge comprising a supply of aerosol-forming substrate and an electrically operated vaporizer.

Abstract: A method and device can alternately deliver high concentration of nitric oxide and oxygen-enriched air. A method of providing a therapeutic amount of nitric oxide to a mammal can include delivering one or more breaths of a therapeutic amount of nitric oxide to the mammal and delivering one or more breaths of an amount of oxygen-enriched air to the mammal immediately after the one or more breaths of the therapeutic amount of nitric oxide.

Abstract: A nasal mask has a flexible bottom edge portion and side portions. A delivery device includes a holding chamber coupled to the nasal mask. A method of delivering an inhalable substance includes positioning a nose of a user in a cavity of the nasal mask, inhaling through the nose, and orally soothing the user with a soothing device.

Abstract: There is described an aerosol-forming substrate for use in combination with an inductive heating device. The aerosol-forming substrate comprises a solid material capable of releasing volatile compounds that can form an aerosol upon heating of the aerosol-forming substrate and at least a first susceptor material for heating of the aerosol-forming substrate. The first susceptor material is arranged in thermal proximity of the solid material. The aerosol-forming substrate further comprises at least a second susceptor material having a second Curie-temperature which is lower than a predefined maximum heating temperature of the first susceptor material. There is also described an aerosol-delivery system.

Abstract: A nosepiece for delivering substance to a nasal cavity of a subject, the nosepiece comprising a body part which comprises a base portion which defines a flow passage therethrough, and a projection at a distal end of the base portion which at least in part provides a tip of the nosepiece and confers a rigidity in the sagittal direction, which enables the tip to open fleshy tissue at an upper region of the nasal valve and thereby expand an open area of the nasal valve, and a flexibility in a lateral direction, orthogonal to the sagittal plane, which facilitates insertion of the tip into the nasal valve.

Abstract: A personalized drug delivery apparatus including drug containing structure; a spout configured to receive full lung exhalation; a mechanism configured to determine a personalized drug dosage according to the exhalation, the spout further configured to enable inhalation of the determined dosage.

Abstract: A portable heated mist inhaler has a body, a supply tank of liquid, an atomizer for atomizing the liquid, and a thermostatically controlled heated nozzle. The supply tank feeds liquid to the atomizer. The atomizer creates a stream of mist from the liquid and entrained surrounding air. The mist is heated inside the nozzle so that it will be comfortable for the user. The portable heated mist inhaler has a battery which powers the atomizer and the heated nozzle.