Abstract: The present invention relates to the use of a combination of a protease and an inner salt of a quaternary amine carboxylic acid for the preparation of an agent for the treatment and/or prophylaxis of coccidiosis and bacterial infections such as necrotic enterities in animals. Preferred embodiments of the invention comprise the inclusion of a xylanase and/or an ?-amylase in the agent. A nutritional additive comprising a combination of an inner salt of a quaternary amine carboxylic acid protease and (optionally) a xylanase and an ?-amylase is also disclosed. It can be used for improving the rate of weight gain of animals.

Abstract: A composition and method is provided for promoting weight loss in a mammal by feeding effective amounts of at least three nutrients selected from L-carnitine, chromium, Vitamin A, and a source of carbohydrates selected from a low glycemic index grain. The composition preferably includes all four nutrients and may be fed in an amount of 1.0 to 10.0 mg of L-carnitine per kilogram of body weight per day, from about 5.0 to about 15.0 micrograms of chromium per kilogram of body weight per day, and from about 1.0 to 3.0 grams of starch per kilogram of body weight per day.

Abstract: This invention describes feed supplement, and processes which increase the amount of essential fatty acids in the milk, eggs, meat and other by-products from animals including dairy cattle, beef cattle, goats and poultry. The food supplement described herein includes specific fish meal, fish oil, algae or plant dietary supplements combined with a natural ingredient/coating mixture, which can be either talc, clay or combinations; or mixtures of talc or clay with flax sprout powder to achieve enhanced levels of the essential fatty acids in the milk, eggs, meat and processed livestock products from animals fed this dietary supplement. In ruminants, the natural ingredient/coating mixture prevents microbial degradation of the essential fatty acids in the rumen stomach of the animals fed with this composition, thus providing more of the essential fatty acids to the animal, for their use. This in turn results in improved concentrations in the milk, meat and processed products from these animals.

Abstract: This invention discloses a medication combination, consisting of Baizhu, Danggui, Hanxincao, Huotanmucao, Ainaxiang, Shuodiao, Malan, Ludou, Canger, Daqinggen, Banbianlian, Xingren, Nuzhenzi, Qianhu, Jiatonghao, Yinchenhao, Yujin, Zhishi, Banxia, and Fuling for treating hepatoma and pancreatic cancer, modifies the conventional extraction procedure and is characterized by the inclusion of Poria, which possesses an anti-tumor ability, as the excipient. This medication combination is based on a novel and continuous theory for cancer therapy and traditional Chinese medicine theories. It has made use of nature and characteristics of those abovementioned medications to lead and change the environments for cancer growth inside the patients' bodies, and then to result in the discomfort and revulsion of cancer cells in such environments.

Abstract: A food supplement formulation consists essentially of flaxseed oil and lipase.

Abstract: A pet food product and process for producing the pet food product for use in maintenance of healthy joints and alleviation of arthritic symptoms in companion animals, the pet food comprising an effective amount of an active extract of Perna canaliculus. The extract can be either a powder or lipid extract. Preferably in an amount that provides for a dosage range of generally 0.18 to 114 mg of a powder extract/kg of body weight/day in a companion animal or an amount of generally 1.5 to 1000 mg of a powder extract of Perna canaliculus per 400 kcal of pet food product.

Abstract: A method of rearing aquatic species is provided, comprising feeding the aquatic species during at least part of the larval and/or post-larval state with prey organisms, such as Artemia or rotifers, having in their total lipid content a DHA content of at least 12 wt %. The method is suitable for the rearing of fish species such as halibut, turbot, bass, bream and flounder. The total lipid content of the prey organisms further including highly unsaturated fatty acids comprising 18:3, 18:4, 20:4, 20:5 (EPA) and 22:5 fatty acids. Also the prey organisms include 5 to 35 wt % phospholipids of the total lipid content, wherein the total lipid content is at least 20 wt % on a dry weight basis.

Abstract: Novel bioactive peptide compositions and process for producing the same and the use of such compositions for enhancing the growth of warm blooded animals and fish is disclosed.

Abstract: Aureobasidium ?-1,3-1,6 glucans and compositions containing such glucans, as well as methods of their preparation. Aureobasidium medium that contains ?-1,3-1,6 glucans, particularly medium produced by Aureobasidium strain FERM P-18099. The ?-glucans of the present invention have a variety of industrial and commercial uses, including applications in pharmaceutical or medical products or treatments, for the removal or control of environmental or microbiological contaminants, in cosmetics, and in nutritional products and foods.

Abstract: A pet food composition and method is provided for reducing inflammatory response in cats. The method includes administering a pet food composition including omega-6 and omega-3 fatty acids in a weight ratio of about 5:1, where the majority of omega-3 fatty acids comprise alpha-linolenic acid. Flaxseed oil is the preferred source of alpha-linolenic acid.

Abstract: Mutants of P. haemolytica provide excellent safety and efficacy when used as vaccines in ruminants, for example cattle, sheep, and goats, subject to pneumonic pasteurellosis. They can be administered by a variety of routes. Especially preferred is the use in animal feeds. The mutants are not reverting and contain no foreign DNA and no introduced antibiotic resistance genes.

Abstract: The present invention is to a safe, biodegradable trace metal binding system that effectively delivers chromium, cobalt, copper, iron, manganese, molybdenum, selenium and zinc to animals. The method of preparing an animal foodstuff composition involves the steps of: providing transgenic algal cells comprising a nucleotide sequence, the nucleotide sequence being capable of expressing a non-native metal-binding protein in the transgenic algal cells; binding the metal-binding protein with at least one metal so as to produce a metal-bound adduct of the metal-binding protein; and admixing the metal-bound adduct with animal foodstuff. The invention is also to a animal foodstuff composition comprising animal foodstuff and transgenic algal cells expressing a non-native metal-binding protein in the transgenic algal cells, such that the transgenic algal cells contain the metal-binding protein and the metal-binding protein being bound to a metal.

Abstract: A calendered hydrocolloid dressing for the wound care and a one step method of manufacturing the hydrocolloidal dressing are described. In particular, the invention is concerned with a hydrocolloid dressing which is absorbent, non-damaging to the skin and comfortable to the user preferably having at least a thermoplastic elastomer backing and water absorbent polymeric adhesive layer.

Abstract: Fecal bacterial contamination in an animal is reduced by providing it with drinking water containing a microbiocidally-effective amount of halogen-based microbiocide resulting from mixing with water (A) a product formed in water from (i) bromine, chlorine, or bromine chloride, or any two or more thereof, (ii) a water-soluble source of sulfamate anion, and (iii) a water-soluble base; (B) at least one 1,3-dihalo-5,5-dialkylhydantoin in which one of the halogen atoms is a chlorine atom and the other is a chlorine or bromine atom, and in which each alkyl group, independently, contains in the range of 1 to about 4 carbon atoms; (C) at least one 1,3-dibromo-5,5-dialkylhydantoin in which one of the alkyl groups is a methyl group and the other alkyl group contains in the range of 1 to about 4 carbon atoms; or (D) any two or more of (A), (B), and (C).

Abstract: It is an object of the present invention to provide immunopotentiators and immunotherapeutic formulations available at low cost and having a benign side effect profile. According to the present invention, an LAK activity enhancer containing an extract of Lentinus edodes mycelium and an LAK activity-enhancing formulation containing said enhancer are provided.

Abstract: The invention is a dietary supplement for animals, especially dogs, for treating arthritis and joint discomfort. A biscuit form of the supplement may be in the form of a conventional carrier composition of, for example, typical dog biscuit materials including cereal grains, vegetables or animal meat, fat and by-products. Typically, the biscuit contains about 89-97 weight percent (wt. %) of the conventional carrier composition. Optional vitamins and minerals may also be added to the carrier material, typically in about the 1-5 wt. % range. Importantly, the biscuit of the present invention contains about 3-7 wt. % of an arthritis-treating combination, namely, glucosamine sulfate, vitamin C and an array of intracellular ions namely potassium, sodium and iodine. The glucosamine component is present by weight at approximately the same level as the vitamin C, and at approximately 10 (ten) times the level of the sum of the above-named intracellular ions.

Abstract: An edible product in accordance with the present invention involves an edible inner component made from a first material and an edible outer cover component substantially completely encapsulating the edible inner component. In one form of the invention, the inner component is in the form of a hairball treatment for cats and the outer component is a dough-like material. A system for producing the edible product includes a first material source for supplying a first edible material to form the inner component of the edible product, a second material source for supplying a second edible material to form the outer component of the edible product, and an extruder for continuously coextruding the first edible material and the edible second material to produce an elongated rope of edible product. A crimping apparatus receives the longitudinal rope extruded from the extruder for crimping the longitudinal rope to separate the longitudinal rope into individual edible products.

Abstract: This invention provides methods and formulations for treating an inflammatory disease or reducing an inflammatory reaction comprising administering a fortified formulation comprising stabilized rice bran derivative and a fortification agent. Preferred rice bran derivatives are rice bran oil and the solubilized fraction of rice bran. Preferred fortification agents are glucosamine derivative, methylsulfonylmethane, yucca concentrate, and grape seed extract.

Abstract: The present invention is a method for pigmenting a food or foodstuff comprising combining in a source of feed, a carotenoid ester of formula I: wherein R is methyl, C3-16-alkyl, C3-16-alkenyl, or C5-8-cycloalkyl. Further embraced by the invention are the carotenoid-enriched feeds, e.g., for poultry, fish, or crustacea, premixes for incorporation in such feeds, and beadlets containing the carotenoid ester for incorporation in such premixes. A further aspect of the present invention is carotenoid esters of formula I.

Abstract: A rumen bypass fat supplement for ruminant animals such as cattle is produced by: (a) blending about 40 to 90 parts by weight fat and about 1 to 10 parts by weight of an emulsifier; (b) adding about 5 to 20 parts by weight water to form an emulsion; (c) adding about 5 to 20 parts by weight of a Group II metal compound to the emulsion to form a reaction mixture and to initiate a salt formation reaction; (d) stirring the reaction mixture until it forms a hardened mass; (e) cooling the hardened mass to a temperature below about 100° F.; and (f) grinding the hardened mass into small particles.

Abstract: Method of preventing parturient hypocalcemia and milk fever (parturient paresis) in lactating animals comprising administering to the animal during the dry period a compound which reduces absorption of calcium from the drinking water and/or from the ration of said animal. The method is based on the powerful, natural calcium regulating mechanisms and is applicable under commercial farming conditions.

Abstract: A ruminant direct fed microbial composition of matter comprising an acidosis inhibiting effective amount of Propionibacterium P-63 is provided. Also disclosed is a process for reducing acidosis in ruminants or scours in swine by administration of the bacterium to the ruminant or swine. The microbial composition may be administered by itself, or combined with animal feed and/or lactic acid producing cultures.

Abstract: This invention features an oral vaccine that includes a multiple-cell organism for use as food for an aquatic animal to be vaccinated, and a single-cell organism fed to, and as a result, bioencapsulated by, the multiple-cell organism. The single-cell organism has been transformed to express a recombinant antigen that induces an immune response in the aquatic animal and thereby vaccinates the aquatic animal (e.g., a fish or a shrimp).

Abstract: The invention relates to compositions and methods for promoting production gains in animals, and of enhancing the efficacy of therapeutic agents. The gains are achieved through reduction in stress, including through the use of antistress agents. Compositions comprising therapeutic agents such as anthelmintics, and antistress agents are provided.

Abstract: A liquid vitamin composition comprising (a) a first liquid vitamin formulation comprising vitamins A, D3, B12 and optionally vitamin E, (b) a second liquid vitamin formulation comprising vitamins B1, B2, B3, B5, B6, and H, and (c) a third liquid vitamin formulation comprising vitamin K3 wherein the three formulations are separate solutions.

Abstract: An attractant composition for application to fishing lures is composed of about 10-45% bees wax and up to about 75 % menhaden oil.

Abstract: The present invention provides improved chlortetracycline-containing animal feed compositions and processes and apparatuses for their preparation. In certain embodiments, raw fermentation broth comprising chlortetracycline is divided into two portions. The first portion is mixed with a compound that complexes chlortetracycline. The second portion is acidified and the solids are removed. The acidified liquid is treated with a complexing agent to produced a chlortetracycline complex. The first and second portions thus treated are then mixed and the mixture is passed on to a filter press or other means for separation of the solids to produce a wet cake comprising complexed chlortetracycline. In alternative embodiments, the second portion may be acidified and filtered and admixed with the first portion prior to the complexing step. The resulting mixture is passed on to a filter press or other means for separation of the solids.

Abstract: The present invention pertains to novel strains of lactic acid bacteria capable of reducing an individual's tendency to react allergic against a variety of different allergens. In particular, the present invention relates to recombinant strains of lactic acid bacteria that express surface polypeptides which include peptides or antibody fragments acting as mimic for at least a part of the Fc region of IgE-molecules. The invention also pertains to food or pharmaceutical compositions containing said micro-organisms or active fractions thereof.

Abstract: A method of stimulating or enhancing an ornithine-urea cycle in ruminant gut tissues, which entails either feeding to a ruminant an effective amount of a ruminant feed or feed supplement containing an effective amount of a compound which stimulates activity of one or more enzymes required in the ornithine-urea cycle.

Abstract: The present invention provides a feedstock for intensive feeding of replacement dairy heifers to promote rapid growth, and facilitate early breeding and first calving at an age of about 20-24 months. The calved heifers subsequently yield increased first lactation milk production and lifetime milk. An essential ingredient of the invention feedstock is conjugated linoleic acid derivative having remen-bypass properties. The quantity of conjugated linoleic acid derivative is effective for prevention of mammary gland tissue damage by minimizing mammary fat content. A preferred feedstock includes a content of slow-release degradable nitrogen source for efficient rumen fermentation, and a content of rumen-bypass protein.

Abstract: Methods for the formulation of microbial feed additives with animal feed and methods of administering microbial feed additives are disclosed.

Abstract: A method for the preparation of a handleable, flowable coated cottonseed product is provided which involves coating cottonseed with a composition of (a) water or a liquid feed product, (b) a soluble phosphorous source and (c) a metal compound capable of interacting with the soluble phosphorous source to form a coating on the cottonseed, and curing the coating formed thereby, and the flowable cottonseed product formed thereby, as well as its use as a feed supplement for ruminants such as cattle, as a plantable source of cottonseed, and in a method for treatment and/or prevention of urinary calculi or prevention of milk fever in cattle.

Abstract: A chewable or non-chewable, palatable and shelf stable dietary supplement for animals including a carrier matrix formed of a natural substance and an effective amount of a medicament intermixed with the carrier matrix. Methods for administering a medicament to an animal may include forming a slurry from a natural substance; mixing an effective amount of a medicament with the slurry to form a mixture; pouring the mixture into a mold; freezing the mixture to form a frozen mixture; drying the frozen mixture to form a freeze-dried dietary supplement; and administering the dietary supplement to an animal. Methods for preparing a dietary supplement may include providing a natural substance to form a carrier matrix for the medicament; slurrifying the natural substance to form a slurry; mixing an effective amount of the medicament with the slurry to form a mixture; pouring the mixture into a mold; freezing the mixture; and removing moisture from the mixture to form a shelf-stable dietary supplement.

Abstract: Improved daily ration mammal feeds are provided which include minor amounts of active such as heartworm preventative drugs, in order to ensure that a mammal consuming the feed receives quantities of active sufficient to establish and maintain substantially constant concentrations of the active in the pet's bloodstream. The feeds may be produced by methods including extrusion with addition of minor quantities of active therein so as to uniformly distribute the active throughout the product.

Abstract: The present invention provides a method for beneficial control of body condition and dietary energy balance in dairy cattle during colostrum milk production. An important aspect of the beneficial control is the provision of a feedstock which has a supplemented content of trans-10, cis-12 conjugated linoleic acid derivative having rumen-bypass properties. The ingested quantity of CLA derivative ingredient per cow is effective for lowering and maintaining the fat content of colostrum milk in the range between about 4-6 weight percent and for increasing milk yield. The presence of cis-9, trans-11 conjugated linoleic acid structural isomer in an invention feedstock is minimized, because it counteracts the beneficial effects of the trans-10, cis-12 conjugated linoleic acid structural isomer, such as reduction in milk yield.

Abstract: A process for feeding an animal a diet which alters the function and morphology of the gastrointestinal tract (GIT), a large lymphoid organ in the animal and which improves glucose metabolism, satiety, and nutrient absorption. The process involves feeding a companion animal such as, for example, a dog or cat a diet of a pet food composition containing fermentable fibers which have an organic matter disappearance (OMD) of 15 to 60 percent when fermented by fecal bacteria for a 24 hour period, the fibers being present in amounts from about 1 to 11 weight percent of supplemental total dietary fiber. The animal is maintained on the diet for a sufficient period of time to allow the fermentable fibers to ferment in the GIT of the animal.

Abstract: Methods and compositions are directed towards a product comprising a food serving that includes at least one of silymarin, an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, and glucuronic acid in an amount effective to reduce volatile sulfur compounds in breath of an individual at least 10% when the food serving is administered to the individual. Preferred food servings are packaged to form a standard serving size. Thus, particularly contemplated methods comprise a step in which a standard serving size is identified. In a further step, at least one ingredient selected from the group consisting of silymarin, an antioxidant, glutathione, a methyl group donor, a sulfur group donor, acetyl CoA, and glucuronic acid is included in the serving size, and in a still further step, the product is advertised as a treatment of bad breath.

Abstract: A method of fattening fowls comprising the step of administrating one or more running neuron inhibitory substance(s) is provided. Especially, a method of fattening fowls is provided, wherein fowls are administrated by a substance selected from the group consisting of GABAB receptor agonist, GABAA receptor agonist, GABAA receptor enhancer, kainate receptor antagonist and a combination thereof or fowls are provide with a feed comprising the substance or a combination thereof.

Abstract: A method of encapsulating a product to make capsules is disclosed; each capsule (12) is comprised of a shell (10) which holds the product and is formed of polymeric material which consists substantially totally of a single polymer. A method of encapsulating comprises forming droplets (4) of a liquid mixture of the product and a single suitable prepolymer and then exposing the droplets to a polymerising medium (8) for the prepolymer so as to polymerise the outer surfaces of the droplets, thereby forming the shells and thus the desired capsules (12). An alternative method is disclosed in which the method of encapsulating comprises forming shells containing no product by exposing droplets of a prepolymer to a polymerising medium for the prepolymer, so as to polymerise the outer surfaces of the droplets and thus form the shells and exposing these shells to an environment containing the product, and causing or allowing the product to diffuse through and into the shells, thus forming the desired capsules.

Abstract: The present invention discloses a method and composition for the treatment of bacterial contamination of food by the use of a phage associated lysing enzyme, preferably blended with an appropriate carrier. The method for treating food stuffs comprises treating the food stuffs with an anti-infection agent comprising an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for the bacteria. Additionally, chimeric lytic enzymes shuffled lytic enzymes, and holin proteins, either alone or in combination, may be used to treat or prevent bacterial contamination of foodstuffs. The lytic enzyme can be used for the treatment or prevention of various strains of Staphylococcus, Streptococcus, Listeria, Salmonella, E. coli, Campylobacter, Pseudomonas, Brucella, other bacteria, and any combination thereof.

Abstract: The present invention provides a method of treating farrowing sows to increase pig production including the steps of determining the zinc concentration of swine blood or tissue samples, comparing the determined concentration with a predetermined adequate concentration range for swine, and then supplying chelated zinc to the sows when the determined concentration is below the adequate concentration range. The chelated zinc may be supplied to the sows through the water or feed, or even supplied by injection. The chelated zinc is preferably supplied during the lactation period since this is the time when the zinc is most critical in determining increased production in future litters and conception rates. Zinc in the chelated form is readily available to the sow and therefore rapidly corrects any deficiency that may exist. An alternate embodiment of this invention includes supplying chelated manganese in addition to the chelated zinc.

Abstract: Anthrax bio-terrorism is a poor man's nuclear bomb with devastating effects on the freedom and economy of any nation. No nation is immune. Urgently, there is a need for life saving technology that can be readily available and deployed in real time. Polystyrene sulfonate is the answer. It is life saving and will help in the development of next generation superior vaccines.

Abstract: A nutritional feed supplement composition for post rumen metabolism in ruminant animals composed of spheroid nutrient particles coatingly covered with divalent metal salts which are insoluble in near-neutral rumen fluid but soluble in acidic post rumen digestive fluids. The composition protects nutrients which would be of no value if exposed to rumen fluids but are beneficial when available for metabolism in post rumen digestive fluids. The nutrients may be dispersed in inert powders formed into spheroid particles, and the divalent metal salts may be dispersed in a resin membrane insoluble in all ruminant fluids. Nutrient particles in the composition include enzymes, amino acids, vitamins, single cell proteins, and medicinal materials. The divalent metal salts include magnesium phosphate, magnesium ammonium phosphate, and magnesium stearate. The resin membranes include polyurethane, polyethylene and polyacrylonitrile-butadiene-styrene.

Abstract: The present invention provides an oral administration form for animals, especially pets, comprising an oily liquid and at least one solid, oil-insoluble active ingredient dispersed in said oily liquid. The suspension is of a kind that n may be homogenized by shaking, and that may be easily poured out of a bottle. The oral administration form of the invention is preferably palatable to animals, it exhibits outstanding stability with water-sensitive active ingredients, and is readily accepted by animals that has to take it.

Abstract: The present invention relates to a solid dispersion of quinolone- or naphthyridonecarboxylic acids in an insoluble matrix representative of a shellac, and methods preparing and using the same in masking the taste and improving the uptake by animals.

Abstract: The invention provides a method of increasing fiber digestion in ruminants by providing a feed additive or feed composition comprising at least one protease. Specifically, the invention provides a method of increasing digestibility of a forage or a grain feed comprising providing at least one protease; providing a forage or a grain feed suitable for a ruminant animal; applying the protease to the forage or the grain feed; and administering the composition to the animal, whereby an increase in digestibility is effected. The invention further extends to feed additives and feed compositions comprising proteases, preparations and uses thereof.

Abstract: The subject invention provides methods of inducing the loss of adipose tissue by providing a diet high in calcium. In one aspect of the invention, the calcium is provided in the form of dairy products. In yet another aspect of the invention, calcium is provided in the form of a dietary supplement, such as calcium carbonate, of vitamin supplements. Methods of suppressing [Ca2+]i levels in individuals are also provided. The subject invention also provides methods of stimulating lipolysis, inhibiting lipogenesis, and increasing the expression of white adipose tissue uncoupling protein 2 (UCP2). The subject invention also provides methods of increasing the core temperature of an individual.

Abstract: An animal feed composition utilizing a humate and/or a modified humate as an ingredient thereof to reduce the odor of manure. The humate and/or modified humate is incorporated with the animal feed in an amount of from about 0.05% to about 5% on a dry weight basis.

Abstract: Health foods are produced containing a biomass obtained by culturing cells of a purple photosynthetic bacterium (for example, Rhodopseudomonas capsulate FERMBP-7434 strain) and optionally in a mixture with a lactic acid bacterium (for example, lactobacillus). These health foods contribute to the maintenance of human health in good conditions or regain thereof even at a small dose causing little burden.

Abstract: The subject invention concerns novel biopesticides and their use to control cockroaches, carpenter ants, and pharaoh ants. Specifically, highly virulent isolates of Beauveria bassiana in an agricultural composition, can be used to effectively control these pests. Exemplified are Beauveria bassiana No. 447, ATCC 20872, and Beauveria bassiana Sp111, ATCC 74038. Also described are unique formulations which are highly effective for delivering biocontrol agents to target pests. By using these novel compositions, target pests can be controlled without the environmental and public safety hazards presented by chemical control agents.