Abstract: The present invention relates to a food composition for domestic carnivores which makes it possible to prevent or correct pigmentation abnormalities and/or to improve the quality of the fur of the said domestic carnivores, characterized in that it contains a source of free tyrosine representing at least 5% of the total tyrosine supplied. The invention also relates to a method for preventing or correcting pigmentation abnormalities of the fur of domestic carnivores that uses said food composition.

Abstract: A composition and method for enhancing immune response and improving the overall health of canines is provided which includes feeding the canines a dietary composition containing an effective amount of garlic in an amount of from about 1 to 10 g/kg diet. The dietary composition, when fed to canines, provides antioxidant, anticancer, and immunomodulatory benefits. The canines are fed the composition containing an effective amount of garlic in a quantity and frequency appropriate for their nutritional needs resulting in an enhanced immune response by increased lymphocyte blastogenesis and improves the overall health of the animal.

Abstract: The present invention is directed to isolation and identification of plant proanthocyanidin extracts and particular proanthocyanidin compounds for prevention and treatment of urinary tract infections caused by P-type Escherichia coli. These extracts can be obtained from any proanthocyanidin-containing plants, including plants of the families Ericaceae, Rosaceae, Pinaceae, Vitaceae and the like. Preferably the extracts are from cranberry plants (especially, Vaccinium macrocarpon) and other plants, particularly fruit and berry plants from the Vaccinium spp. The extracts and compounds are also provided as pharmaceutical compositions, food additives and food compositions, especially beverages, ground meat preparations and cranberry-containing food products. The invention also relates to methods of reducing pathogenicity of P-type E. coli in the digestive tracts of cattle and reducing P-type E. coli contamination in ground meat as well as methods of detecting P-type bacteria.

Abstract: The present invention relates to methods for preparing collagen, especially type I collagen. In particular, the present invention provides methods for the preparation of collagen suitable for biomedical and veterinary applications. The collagen prepared according to the present invention provides numerous desirable characteristics for applications such as implantation, transplantation, and grafting.

Abstract: A polypeptide-polymer conjugate is prepared having one or more polymers covalently bound to a polypeptide. The polymer has the general formula; EOXPOY wherein EO is ethylene oxide, PO is propylene oxide, x=1−99%, y=1−99%, x+y=100%, and x and y are in a ratio range of 10:90 to 90:10, more preferably 40:60 to 60:40, or in a 50/50 ratio. The polymer, which can be a block polymer, typically has a molecular weight in a range of 100 to 100,000 daltons, and the polypeptide may contain 1 to 100 polymer molecules. Coupling the polypeptide, in particular enzymes, to the polymer reduces respiratory allergenicity of the polypeptide. Industrial compositions such as detergent compositions, personal care compositions, compositions for processing/treating textiles, and food and feed compositions containing the polypeptide-polymer conjugate have reduced respiratory allergenicity.

Abstract: The present invention provides, amongst others, a means to overcome the problem of oxidative stress in the domestic cat and dog. There is provided a method for increasing the plasma vitamin E level in a cat or dog, the method comprising the step of administering to said cat or dog, an amount of Vitamin E sufficient to increase the plasma vitamin E level. There is also provided use of vitamin C in the manufacture of a dog or cat foodstuff for the prevention or treatment of a disorder which has a component of oxidative stress. The present invention utilizes an antioxidant cocktail to overcome the problem of oxidative stress in a cat or dog. Such cocktail can be used to prevent or treat a disorder which has a component of oxidate stress or to maintain, optimise or boost immunological response.

Abstract: The invention relates to a method for increasing the concentration of the cis-9, trans-11 isomer of octadecadienoic acid in the milk fat and/or the tissue fat of a ruminant. In the method the ruminant is fed the trans-11 isomer of octadecenoic acid either as such or mixed with other feed, separately or together with other fatty acids.

Abstract: A stable product containing finely a dispersed carotenoid for use in supplementing aqueous systems, such as foods, beverages, and personal care products, with the carotenoid. An emulsifier is dissolved in water and an anti-foam agent and a source of the carotenoid are added to the solution. The concentrated product may be added to the aqueous systems or dried to form a powder that is readily dispersible in aqueous systems. The product may also include an antioxidant to preserve the activity of the carotenoid. Emulsifiers particularly suited for use include sucrose fatty acid esters. The product is produced without the use of organic solvents or elevated temperatures.

Abstract: The invention relates to a feed for neonates breeding producing a metabolic energy of 4200 calories and a process for using such feed.

Abstract: A method for increasing the hunt performance of a hunting mammal which includes orally administering to the mammal an effective amount of a diet comprising unsaturated fatty acid eicosapentaenoic acid (EPA), unsaturated fatty acid docosahexaenoic acid (DHA), or both unsaturated fatty acids, in a total amount of the diet greater than about 0.20 weight percent. The invention also provides dietary compositions that yield other beneficial results.

Abstract: The present invention is directed to a ready-to-use composition for supplementing nutritional content of a pet food. The composition comprises, on a dry matter basis, from about 15 to about 80% by weight of a protein component, from about 20 to about 85% by weight of a humectant, and from about 1 to about 50% by weight of a lipid component. The composition does not require sterilization or addition of chemical preservative, thereby making the invention suitable for delivery of nutritional functional ingredients that are heat labile.

Abstract: The present invention relates to the use of a non-digestible carbohydrate in the manufacture of a composition for treating or preventing pathogenic bacteria in the large intestine of a pet animal. It also provides a method for the prevention or treatment of a pathogenic bacteria in the large intestine of a pet animal, the method comprising administering to said pet animal a composition which comprises a non-digestible carbohydrate.

Abstract: This invention relates to an effective intervention plan. In one aspect, the invention relates to the treatment of various symptoms, conditions or diseases, such as diarrhea, constipation, congestion, eczema, asthma, fatigue, muscle weakness, tension and spasms, irritable bowel syndrome, swelling, anxiety, multiple chemical sensitivities, moderate to excessive and moderate to severe symptoms due to food allergies, sensitivities and intolerances, bloating, pain, headaches, leaky gut, hypersensitivity, sleep difficulties, severe under weight, eating disorders, obsessive, compulsive disorders, panic attacks, sensory sensitivities, Alzheimer's disease, acid refulx, irritability, delayed motor skills, delayed social skills, autism, PDD, infantile spasms and seizures by withholding for a period of at least 5 days all foods except for root crops.

Abstract: A cruciferous plant, cut pieces thereof, and juice of the plant and the cut pieces are subjected to at least one treatment selected from the group consisting of anaerobic treatment, 25 to 50° C. thermal retention treatment, and glutamic acid treatment, to enrich &ggr;-aminobutyric acid (GABA), thereby obtaining a cruciferous plant, cut pieces, and juice containing GABA in various concentrations. By performing microwave radiation, blanching, drying, and the like for the GABA-enriched plant and the like as required, dried powder of the cruciferous plant, the cut pieces, and the juice, containing GABA in a high concentration and maintaining green color, is obtained. Food material, medicine material, and feed made of the cruciferous plant containing GABA in a high concentration are obtained.

Abstract: The present invention is directed to pharmaceutical compositions, which are palatable to companion animals wherein the pharmaceutical composition comprises pharmaceutically effective amounts of pharmaceutically active agents and palatability improving agents.

Abstract: The invention relates to an animal feed which contains conventional animal feed substances like grain or grain products, maize, protein and aromatic amino acids, vitamins, mineral additives like salts, phosphates, lime, enzymes and the like, or an animal feed additive, whereby to reduce the enzymatic decomposition of the essential aromatic amino acids it contains one or more benzophenanthridine alkaloids or their derivatives or synthetic analogs in an effective amount. Furthermore the invention relates to the use of benzophenanthridine alkaloids, their derivatives or synthetic analogs and a medicament.

Abstract: A process is provided for limiting weight gain in cats. The process includes feeding the cat a pet food composition that includes a source of protein, a source of fat, and a source of carbohydrates from a grain source that excludes rice. Use of preferred low glycemic index grain sources that comprise a blend of corn and sorghum; a blend of corn, sorghum, and barley; or a blend of corn, sorghum, and oats, has the effect of decreasing the postprandial blood glucose and insulin response of the cat as compared to when feeding a rice-based diet. The result is that the animal becomes satiated and voluntarily decreases its intake of food, causing less weight gain. This effect is even more marked when the composition is fed to male cats.

Abstract: The invention relates to a method of producing oily suspensions of water-soluble vitamins which comprises

Abstract: A method for reducing bacterial enteropathogens in fowl subjected to feed withdrawal, involving withdrawing feed from fowl and orally administering to the fowl an effective amount of a cocktail sufficient to reduce bacterial enteropathogens in the crop of the fowl, wherein the cocktail contains contains water, a carbohydrate (e.g., glucose, sucrose), and optionally a protein source, a vitamin source, an organic acid, an emulsifier, a mineral source, and mixtures thereof.

Abstract: Enzyme feed supplements containing fungal cellulase produced by Trichoderma viride are specially adapted for increasing protein digestability of dairy cow and cattle feed. Preferred embodiments of the present invention include enzyme formulations adapted for application to corn and enzyme formulations adapted for application to grain sorghum, to which is added Trichoderma viride cellulase. An increase in protein digestability has been evidenced by increased protein content of milk and increased nitrogen retention from the feed.

Abstract: The invention pertains to chewable controlled-release multiparticulate pharmaceutical compositions for companion animals and method of making same.

Abstract: The present invention is directed to the intramuscular use of ropivacaine for the manufacture of a medicament for use in the treatment of muskuloskeletal pain, in particular myofascial pain and tendinitis.

Abstract: The invention provides a synthetic phytase polynucleotide which is optimized for expression in plants and which encodes at thermotolerant phytase, as well as isolated thermotolerant phytase enzyme. Also provided are feed or food products comprising a thermotolerant phytase, and transgenic plants which express the thermotolerant phytase. Further provided are methods for making and using thermotolerant phytases, e.g., a method of using a thermotolerant phytase in feed and food processing.

Abstract: Deer attractant and feed comprising stabilized rice bran and calcium carbonate is disclosed. Limestone is added to the rice during the milling process. The residue from this process, rice bran and a small amount of pulverized limestone, is the cooked in an extruder, resulting in stabilized rice bran. The extrusion process destroys lipase activity and reduces the free fatty acid content to under 4%. The product contains about 12.5% or more protein, and preferably has a 2:1 ratio of calcium to phosphorous. Because of the balanced nutritional analysis and the addition of calcium carbonate to the feed, the product aids in promoting overall deer growth as well as bone growth in bucks. The product also acts as a deer attractant, moving deer toward sources of adequate food supplies and away from cultivated gardens and crops.

Abstract: A process is provided for reducing adiposity in an animal such as a companion animal by feeding the animal an effective amount of Vitamin A for a time sufficient to reduce adiposity in the animal. Preferably, the such effective amount comprises from about 50,000 IU to about 1,000,000 IU of Vitamin A per kilogram of diet. Such an effective amount provides sufficient Vitamin A to decrease accumulation of body fat, increase UCP1 levels, and decrease serum leptin levels in the animal.

Abstract: The invention concerns a rehydration fluid composition, useful in particular for feeding young animals no longer able to digest milk, comprising lactose or glucose or a product based on lactose or glucose: a mineral supplement ensuring restoration of digestive losses. The invention is characterised in that the composition further comprises an efficient quantity of soluble vegetable proteins and vegetable lipids ensuring suitable appropriate energy intake.

Abstract: A method and composition for destruction of infectious prion proteins in tissue, by thermal/enzymatic treatment of the tissue with a prion-destructive protease. The method and composition are applicable to treatment of tissue containing or contaminated with prion protein strains associated with transmissible spongiform encephalopathy (TSE) and/or other prion protein-mediated diseases.

Abstract: The present invention provides equine feedstuffs and methods by which plasma glutamine concentrations in equine animals can be increased or maintained. The present invention provides equine feedstuffs with supplemented glutamine and with optional high levels of fat or oil. Glutamine supplementation provides a pharmacological benefit to the equine animal, for example in respect of one or more or over-training, infection, other stressful conditions or catabolic stress.

Abstract: A solid phytase composition having a phytase activity of above 20 FYT/g is prepared containing a lactic acid source such as corn steep liquor to stabilize the phytase. A starch source, disaccharide, filler, carrier, vitamins and/or minerals may be present in the composition. The composition can be prepared by spray drying or granulation. Granulates are preferred for using the composition to animal feed where the phytase eliminates the anti-nutritional effects of phytic acid.

Abstract: The invention provides methods for making and using thermotolerant phytases, e.g., a method of using a thermotolerant phytase in feed and food processing and feed or food products comprising a thermotolerant phytase.

Abstract: The invention relates to the use of polydextrose for stimulating the immune response (IgA) in the gastrointestinal tract of a mammal. Furthermore, the invention provides a method to potentiate the immunostimulative effect of polydextrose by mixing at least one polyol with polydextrose, said polyol being effective to synergistically increase the immunoglobulin A (IgA) concentration in the gut of a mammal. On the other hand, the invention provides also compositions containing polydextrose and polyols in which the laxative effects of polyols are reduced and which are effective to reduce the amount of biogenic amines in the gut of a mammal.

Abstract: Methods are described for relieving discomforts associated with osteoarthritis or fibromyalgia. The methods comprise the step of delivering by oral ingestion a nutritional supplement consisting essentially of an effective amount of hyaluronic acid, or a salt or digest thereof, and a food acceptable carrier, wherein the effective amount of hyaluronic acid, or a salt or digest thereof, is from about 0.1 &mgr;g to about 400 &mgr;g/kg of body weight.

Abstract: A composition and method for supplementing feed, nutrition and diet systems with bioactive glycerides of conjugated linoleic acid comprised of a synergistic blend of conjugated linoleic bioactive isomers acid in mono-, di-, and/or triglyceride form. The composition comprises (A) bioactive glycerides of conjugated linoleic acid comprised of a synergistic blend of conjugated linoleic bioactive isomers acid in mono-, di- and/or triglyceride form, (B) a carrier medium, and (C) a delivery system as a dietary supplement. The composition provides an effective increase in nutritional, therapeutic, and pharmacological properties in nutrition and diet systems.

Abstract: A food supplement with advantageous physiological effects containing the following essential constituents in a support material (e.g. dairy products, margarine, fruit juice, plant juice, yeast, pectin or olive oil): lecithin, red wine extract and D-alpha-tocopherolacetate in amount ranging from 0.05 to 10.0 parts by weight.

Abstract: An enzymatic synthesis and composition of &agr;-hydroxy carboxylic acid and &agr;-amino acid or peptide co-oligomers is disclosed wherein a residue of the &agr;-hydroxy carboxylic acid is linked to a residue of the &agr;-amino acid or peptide by an amide linkage. Proteolytic enzyme papain catalyzes co-oligomerization of the &agr;-hydroxy carboxylic acid and &agr;-amino acid. The degree and distribution of oligomerization varies upon the type and concentrations of different reaction mixtures utilized and upon the length of allowed reaction time. The resultant oligomers may be provided to ruminants as bioavailable amino acid supplements that are resistant to degradation in the rumen.

Abstract: An antiviral agent which is characterized in containing at least one compound selected from a group consisting of 4,5-dihydroxy-2-cyclopenten-1-one represented by the following formula [I] and an optically active substance and a salt thereof as an effective component.

Abstract: An agent is provided to help animals such as cats, rabbits and ferrets to evacuate the hair taken in at grooming by defecation and thereby avoid a hairball symptom which can cause an alimentary canal fault in the animal. The agent includes more than one of the following materials: kelp, papaya, molokheiya or plantago. In addition, the agent can be incorporated into an animal feed. The agent preferably is only about 1-10% of the content or composition of the animal feed.

Abstract: The present invention relates to a method for supplying bioavailable methionine to a cow which comprises supplying to the cow an ester of methionine or methionine amide and/or an ester of the hydroxy analogue of methionine or a salt thereof.

Abstract: Antibacterial protein complexes designated as Anti-adhesive Lactalbumin Like Protein (ALLP) are obtained by ion-exchange chromatography of casein and alpha-lactalbumin. Casein isolated from human milk by acid precipitation is subjected to ion-exchange chromatography using an NaCl gradient to obtain six fractions. Fraction six contains the antibacterial protein complex and is recovered. Ion-exchange chromatography of human or bovine alpha-lactalbumin using an NaCl gradient resulted in a fraction that was retained and eluted that contained an antibacterial multimeric protein complex. The protein complexes inhibit attachment of S. pneumoniae and H. influenzae to human respiratory tract epithelial cells when tested in vitro, and the protein complexes can be used to treat a bacterial infection in the respiratory tract. The protein complexes are administered in a pharmaceutical composition or in a food or feed-stuff.

Abstract: A stabilized lipid composition of randomly interesterified triacylglycerols (TAGs) that includes, by weight of fatty acid components, long-chain polyunsaturated fatty acids (LC-PUFAs) having at least 20 carbon atoms and a degree of unsaturation of at least 4 and being present in a nutritionally beneficial amount but less than 5% by weight; and medium-chain saturated fatty acids (MC-SFAs) having six to fourteen carbon atoms and being present to promote absorption of the LC-PUFAs. The LC-PUFAs are mono-LC-PUFAs. Also, a nutritional product or infant food product that contains the lipid composition as a portion of the lipids therein, and methods to make such compositions and products.

Abstract: A diet system for promoting comprehensive weight management in companion animals. The diet system includes a stage I pet food product for promoting weight loss and building lean body mass and a stage II pet food product for maintaining the weight loss and the lean body mass.

Abstract: A process for the heterotrophic or predominantly heterotrophic production of whole-celled or extracted microbial products with a high concentration of omega-3 highly unsaturated fatty acids, producible in an aerobic culture under controlled conditions using biologically pure cultures of heterotrophic single-celled fungi microorganisms of the order Thraustochytriales. The harvested whole-cell microbial product can be added to processed foods as a nutritional supplement, or to fish and animal feeds to enhance the omega-3 highly unsaturated fatty acid content of products produced from these animals. The lipids containing these fatty acids can also be extracted and used in nutritional, pharmaceutical and industrial applications.

Abstract: The present invention includes a method for increasing meat production while reducing fat in ruminant and non-ruminant animals and for increasing egg production in poultry and milk production in ruminant animals. The method includes mixing ingredients that include 190 proof ethanol in a concentration of about 9% by weight of a food supplement with clay and a nitrogen source such as urea to form the food supplement. The food supplement for ruminant animals additionally includes a condensed distiller's soluble fraction. The mixed ingredients are added to an animal feed such as corn. The animal feed and supplement are fed to an animal at least one per day.

Abstract: A pet food product and process for producing the pet food product for use in maintenance of healthy joints and alleviation of arthritic symptoms in companion animals, the pet food comprising an effective amount of an active extract of Perna canaliculus. The extract can be either a powder or lipid extract. Preferably in an amount that provides for a dosage range of generally 0.18 to 114 mg of a powder extract/kg of body weight/day in a companion animal or an amount of generally 1.5 to 1000 mg of a powder extract of Perna canaliculus per 400 kcal of pet food product.

Abstract: The development of oviparous species such as birds after hatch is enhanced by feeding a subject prior to hatch. The subject is fed with a nutrient composition and/or an enteric modulator. A preferred nutrient composition contains at least one protein, peptide, amino acid or carbohydrate; a preferred enteric modulator is hydroxymethylbutyrate. Feeding may be accomplished by administering the nutrient composition and/or enteric modulator into the amnion where it is then orally ingested by the subject.

Abstract: A dietary supplement for animals comprising one or more enzymes and a physiologically acceptable carrier.

Abstract: The present invention relates to methods of imprinting fish to be sensitized to an odorant so that modulation of the PVCR in the olfactory apparatus occurs, and then exposing the fish with the same odorant after transfer to seawater or freshwater. The present invention also includes methods of homing or attracting fish, as well as methods for repelling fish by modulating the expression and/or sensitivity of the PVCR in the olfactory apparatus of the fish.

Abstract: An agent protective against drug-induced hepatopathy containing Lentinus edodes mycelium extract.

Abstract: The present invention provides a therapeutic or preventing agent for diseases caused by a decrease in the expression level of Klotho protein in animals or humans and a feed or food and drink for the treatment or prevention of such diseases, which comprise ornithine or a salt thereof as an active ingredient. Also provided are a therapeutic or preventing agent for premature aging-like syndrome of homozygous klotho mutant animals and a feed for the treatment or prevention of the syndrome, which comprise ornithine or a salt thereof as an active ingredient, as well as a method for the treatment or prevention of premature aging-like syndrome of homozygous klotho mutant animals which comprises feeding the animals with the above feed.

Abstract: A composition for use in treating hepatitis includes: 4%-28% Gulancha by weight; 20%-7% Sodium Biborate by weight; 5%-47% Horseradish by weight; and 3%-14% Mysore Gamboge be weight.