Elemental Chlorine Or Elemental Chlorine Releasing Inorganic Compound (e.g., Chlorties, Hypochlorites, Etc.) Patents (Class 424/661)
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Publication number: 20140050774Abstract: The wound treatment therapy deactivates pathogenic microorganisms within the wound environment without disrupting the cell walls. The wound treatment therapy of this invention combines the application of stabilized hypochlorous acid compound with the application of a hydrophobic wound dressing. The application of hypochlorous acid provides the initial anti-microbial agent, which disrupts and eradicates biofilm, as well as, deactivates the harmful pathogenic organisms within the wound environment. The application of the hydrophobic wound dressing, which is designed to bind harmful hydrophobic microorganisms and toxins, provides a mechanical vehicle for physically removing deactivated hydrophobic microorganisms form the wound environment with each dressing change.Type: ApplicationFiled: October 23, 2013Publication date: February 20, 2014Applicant: INTEGRATED HEALING TECHNOLOGIES, LLCInventors: ALBERT RODEWALD, ROBERT STEPHEN PORTER
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Publication number: 20140030360Abstract: A method for manufacturing chlorine dioxide gel includes the following steps: a step of dissolving peg-copolymer bis-decyltetradeceth in hot water to form an aqueous solution of peg-copolymer bis-decyltetradeceth; a step of heating the aqueous solution of peg-copolymer bis-decyltetradeceth obtained in the above step to form a gel like colloid; a step of dissolving pure chlorine dioxide gas in water to form an aqueous solution of chlorine dioxide; and a step of uniformly mixing the aqueous solution of chlorine dioxide and the colloid of peg-copolymer bis-decyltetradeceth to form a chlorine dioxide gel, whereby with the above steps, a method for manufacturing chlorine dioxide gel that stably preserves chlorine dioxide gas in a gel is provided.Type: ApplicationFiled: July 23, 2013Publication date: January 30, 2014Inventor: Hao Chang Yin
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Patent number: 8636987Abstract: A method of whitening a tooth surface including contacting the surface of a tooth with an efficacious amount of a substantially non-cytotoxic composition. The non-cytotoxic composition includes chlorine dioxide and no more than about 0.25 milligrams oxy-chlorine anions per gram of the composition.Type: GrantFiled: July 14, 2009Date of Patent: January 28, 2014Assignee: BASF CorporationInventors: Barry Keven Speronello, Frank S. Castellana, Linda Hratko
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Publication number: 20140023727Abstract: A biocidal composition comprising 2,2-dibromomalonamide and an oxidizing biocide, and its use for the control of microorganisms in aqueous and water-containing systems.Type: ApplicationFiled: March 12, 2012Publication date: January 23, 2014Applicant: DOW GLOBAL TECHNOLOGIES LLCInventors: Freddie L. Singleton, Bei Yin
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Patent number: 8632823Abstract: Super-oxidized water based on hypochlorous acid, such as is obtained by the electrochemical treatment of a saline solution, may be used in the treatment of leg ulcers or other open wounds. Preferably, the pH of the super-oxidized water is in a range of 4 to 7, and the water has a redox potential of >950 mV. Medicaments based on the super-oxidized water may be in liquid or gel form. The super-oxidized water is able to control the microbial population within the wound and at the same time permit cell proliferation.Type: GrantFiled: December 21, 2007Date of Patent: January 21, 2014Assignee: Puricore, Inc.Inventor: Joe B. Selkon
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Patent number: 8632794Abstract: There are provided methods for controlling microbial or biofilm growth, comprising mixing a hypochlorite oxidant and at least one nitrogen-containing compound or salt thereof selected from a particular group of nitrogen-containing compounds and salts to form a biocide, and applying the biocide. Apparatus for practicing the methods are also provided.Type: GrantFiled: January 12, 2005Date of Patent: January 21, 2014Assignee: A.Y. Laboratories Ltd.Inventor: Ayala Barak
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Patent number: 8628788Abstract: Novel formulations containing a non-oxidative biocide, such as DBNPA, and a source of an in situ produced active biocide, such as a concentrated aqueous solution of an inorganic halide salt, are disclosed. These novel formulations are particularly effective in the treatment of water, and are characterized by high stability, desirable rheological properties and an excellent biocidal activity.Type: GrantFiled: February 25, 2007Date of Patent: January 14, 2014Assignee: Bromine Compounds, Ltd.Inventors: David Feldman, Michel Adda, Raymond J. Roccon
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Patent number: 8623392Abstract: An allergen inactivating agent for preventing allergic manifestations or alleviating symptoms by reducing antigenicity of an allergen through contact with the allergen includes dissolved chlorine dioxide as an active ingredient.Type: GrantFiled: February 15, 2008Date of Patent: January 7, 2014Assignee: Taiko Pharmaceutical Co., Ltd.Inventors: Hirofumi Morino, Takashi Shibata
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Patent number: 8613859Abstract: Synergistic mixtures of haloamines and their use to control the growth of microorganisms in aqueous systems are disclosed. The method of using the synergistic mixtures entails adding an effective amount of a monohaloamine and an effective amount of a dihaloamine to an aqueous system. The ratio of monohaloamine to dihaloamine is selected to result in a synergistic biocidal effect.Type: GrantFiled: October 25, 2010Date of Patent: December 24, 2013Assignee: Hercules IncorporatedInventors: Michael J. Mayer, Freddie L. Singleton
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Patent number: 8609594Abstract: According to one aspect of the invention, a method of converting an oxy halide salt into a halide dioxide in a reaction zone under certain conditions is provided. More specifically, the method includes generating chlorine dioxide from a stable composition comprising an oxy halide salt by introducing said composition to a reducing agent and minimum temperature within the reaction zone. According to another aspect of the invention, a composition for a stable chlorine dioxide precursor comprising an oxy halide salt is provided.Type: GrantFiled: February 7, 2013Date of Patent: December 17, 2013Assignee: Sabre Intellectual Property Holdings LLCInventor: John Y. Mason
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Patent number: 8603355Abstract: A composition for stabilizing chlorine dioxide maintains a chlorine dioxide concentration nearly constant in the agent containing chlorine dioxide dissolved therein even when chlorine dioxide is continuously released as gas from agent, and includes a chlorite and a pH adjuster. The pH adjuster is an acid or a salt thereof having a buffering property whose pH is 2.5 to 6.8 as a 5% aqueous solution at 25° C.Type: GrantFiled: June 27, 2011Date of Patent: December 10, 2013Assignee: Taiko Pharmaceutical Co., Ltd.Inventor: Koji Abe
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Publication number: 20130323326Abstract: A composition and method are described for suppressing or preventing fibrous adhesion formation using a multicomponent aqueous oxychlorine composition. Fibrous adhesions typically form during healing of tissue, for example following a surgical procedure. A multicomponent oxychlorine composition is provided for irrigating the tissue which minimizes post-surgical adhesion formation, the composition containing both chlorine dioxide and chlorite ion, and a complex ion thereof. The chlorine dioxide level generally is in an effective range of ClO2 concentration from about 10 ppm to a maximum of about 110 ppm. In a preferred embodiment, a physiological composition is provided in a thickened form to increase retention in the area being treated.Type: ApplicationFiled: August 12, 2013Publication date: December 5, 2013Inventors: Robert D. Kross, Cleva Villanueva
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Publication number: 20130316019Abstract: A process is described for the preparation of a stabilized aqueous solution of oxidizing chlorine (anolyte). The process comprises electrolysis of an aqueous solution of sodium chloride or potassium chloride in an electrolytic cell having at least one anode compartment and one cathode compartment separated by a semi-permeable membrane to obtain an anolyte solution in the anode compartment and a catholyte solution in the cathode compartment, and the addition to the anolyte solution produced in this way of a stabilizing agent selected from the group consisting of hydrochloric acid (HCl) of 50 to 250 mg/l, sulphuric acid (H2SO4) of 50 to 350 mg/l, phosphoric acid (H3PO4) of 50 to 500 mg/l, periodic acid (HIO4) of 100 to 1000 mg/l, sodium chloride (NaCl) from 1 to 30 g/l, or any combination thereof. The stabilized anolyte solution produced with the process according to the invention has an advantage of a reduced pH value and increased redox potential value, preferably greater than 960.Type: ApplicationFiled: April 12, 2013Publication date: November 28, 2013Applicant: DUEDI SRLInventors: Cerrato Sergio, D'angelo Domenico, Monti Daniele, Tartaro Daniele, Venturello Alberto
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Publication number: 20130316020Abstract: This application described a wound dressing comprising an absorbent material, an effective amount of chlorite and an amount of a base to provide a pH of the dressing material greater than or equal to about (10). Advantageously, the wound dressings of the present application provide a convenient source of chlorite that is stable and easy to use.Type: ApplicationFiled: February 9, 2012Publication date: November 28, 2013Inventors: Servet Buyuktimkin, Nadir Buyuktimkin, Edward T. Kisak, Dominic King-Smith, John M. Newsam, Jagat Singh
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Patent number: 8591767Abstract: A functional fluid for the removal of contaminates such as but not limited to, acid causing components in gas, sulfur components and carbon oxides from fluid streams, and removal and treatment of NOX & SOX from post combustion emissions. Also described is the manufacturing process to produce the functional fluid both in a batch atmospheric process system as well as a closed system capable of operating at above or below atmospheric conditions.Type: GrantFiled: December 1, 2011Date of Patent: November 26, 2013Assignee: Specialist Process Technologies LimitedInventors: Theodore E. Dickinson, David John Parkinson, Kevin E. Collier
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Publication number: 20130302443Abstract: Microbial growth in an aqueous system containing borohydride residues is controlled by adding an aldehyde or aldehyde source, followed by adding an active halogen biocide. The active halogen biocide is preferably stabilized by an N-hydrogen compound.Type: ApplicationFiled: January 20, 2012Publication date: November 14, 2013Applicant: Lonza Inc.Inventor: Kevin Janak
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Patent number: 8580233Abstract: A method of whitening a tooth surface including contacting the surface of a tooth with an efficacious amount of a substantially non-cytotoxic composition. The non-cytotoxic composition includes chlorine dioxide and no more than about 0.25 milligrams oxy-chlorine anions per gram of the composition.Type: GrantFiled: July 14, 2009Date of Patent: November 12, 2013Assignee: BASF CorporationInventors: Barry Keven Speronello, Frank S. Castellana, Linda Hratko
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Publication number: 20130295200Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.Type: ApplicationFiled: April 5, 2013Publication date: November 7, 2013Inventor: Nuvo Research AG
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Patent number: 8574605Abstract: The invention includes convenient methods of preparing: (1) highly concentrated liquid bromine-containing biocidal solutions, (2) highly concentrated mixed halogen liquid bromine and chlorine-containing biocidal solutions, and (3) high-activity bromine-containing biocidal solids, all having excellent physical and chemical stability. One method yields solutions that have concentrations of bromine in excess of 18% as Br2 (8% as Cl2) in which the mole ratio of hydroxide ion to hydrogen ion source is at least 1.9:1. Another method employs elemental bromine in conjunction with a solid organic or inorganic halogenating agent to yield halogen solutions at concentrations greater than 22.9% as Br2 (10.2% as Cl2). This method can be performed under conditions that exceed the solubility of the active ingredient such that it crystallizes and is recovered as a hydrated or anhydrous salt in good yield.Type: GrantFiled: October 19, 2007Date of Patent: November 5, 2013Assignee: Enviro Tech Chemical Services, Inc.Inventors: Jonathan N. Howarth, Michael S. Harvey
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Publication number: 20130287722Abstract: The invention relates to a method for producing an ultrapure, aqueous, long-term- and storage-stable, and thus transportable, chlorine dioxide solution, comprising the steps of: providing chlorite, providing peroxodisulfate, and combining chlorite and peroxodisulfate in an aqueous system and in a molar ratio of peroxodisulfate to chlorite [S2O82?]/[ClO2?] of greater than 1, forming the aqueous chlorine dioxide solution, wherein no additional buffer is added to produce the aqueous chlorine dioxide solution. The invention further relates to a corresponding chlorine dioxide solution, to the use of said chlorine dioxide solution, and to a device for producing the chlorine dioxide solution.Type: ApplicationFiled: December 22, 2011Publication date: October 31, 2013Applicant: A.P.F. AQUA SYSTEM AGInventor: Helmut Uhlmann
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Patent number: 8563046Abstract: Certain exemplary embodiments can provide a composition of matter comprising chlorine dioxide dissolved in acetic acid. When stored, a concentration of the chlorine dioxide in the composition of matter can be retained, with respect to an initial concentration of chlorine dioxide in said composition of matter, at, for example, greater than 30% for at least 28 days. Certain exemplary embodiments can provide a method comprising releasing chlorine dioxide from a composition comprising chlorine dioxide dissolved in acetic acid.Type: GrantFiled: August 15, 2008Date of Patent: October 22, 2013Assignee: Dharma IP, LLCInventors: Ken Harrison, Nick Blandford
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Publication number: 20130273174Abstract: The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellancy, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions where the one polyelectrolyte present in molar excess is added in the form of a first aqueous solution during a mixing step to a second aqueous solution comprising the oppositely charged polyelectrolyte present in molar deficiency.Type: ApplicationFiled: May 3, 2013Publication date: October 17, 2013Inventors: David R. Scheuing, David J. Lestage, Carl W. Bennett, Mona M. Knock, Charles W. Scales, William L. Smith, Rui Zhang
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Patent number: 8551534Abstract: The invention described herein is directed to method of treating chronic obstructive pulmonary disease, comprising administering an effective amount of an osmolyte by at least one nasal cannula to a subject in need thereof. Also provided is a nasal cannula system for delivering an osmolyte, comprising a nebulizer and tubing having two ends, where the first end of the tubing is connected to the nebulizer and the second end of the tubing is tapered to fit in the nostril of a subject.Type: GrantFiled: October 10, 2008Date of Patent: October 8, 2013Assignee: Parion Sciences, Inc.Inventors: Richard C. Boucher, Michael Ross Johnson
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Publication number: 20130259955Abstract: The present invention relates to methods of treating or preventing an infection or infectious disease in a mammal, or sanitizing mammalian tissue, or treating or preventing psoriasis in a mammal, comprising topically administering to said mammal an electrolytic acid water comprising free chlorine, wherein: a) from 90% to 99.9% of said free chlorine is present in the form of hypochlorous acid; b) said water has a pH of from 0.5 to 5.0; and c) said water has oxidation reduction potential (ORP) of greater than 1100 mV. The present invention also relates to methods of healing, repair or regeneration of a tissue in a mammal comprising topically administering to said tissue said electrolytic acid water.Type: ApplicationFiled: February 15, 2013Publication date: October 3, 2013Applicant: APR Nanotechnologies s.a.Inventors: Yongge Chen, Roberto De Noni, Giorgio Reiner, Paolo Galfetti
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Patent number: 8545898Abstract: A composition for a broad-spectrum antiviral agent with excellent preservation stability, which comprises a pure chlorine dioxide solution comprising a chlorine dioxide gas dissolved therein, a chlorite, and a pH adjuster.Type: GrantFiled: February 15, 2008Date of Patent: October 1, 2013Assignee: Taiko Pharmaceutical Co., Ltd.Inventors: Toshiaki Fukuda, Koji Abe, Takashi Shibata
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Publication number: 20130251822Abstract: A combination biocide (Glutaraldehyde or OPA), quaternary phosphonium biocide, alcohol, and functional excipients for surface-sterilization of medical instruments and other objects. The quaternary phosphonium biocide is preferably TTPC, and the alcohol isopropyl alcohol. The OPA is the dialdehyde C6H4(CHO)2, which produces an inherent bacteriostatic effect, lowering surface tension, and aiding in the spread of the TTPC on the instrument surface where it is readily absorbed by the negative surfaces of proteins and bacteria. It thus serves as a binding agent between the TTPC and the application surface.Type: ApplicationFiled: May 21, 2013Publication date: September 26, 2013Inventor: Howard Martin
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Publication number: 20130236569Abstract: There is provided an automated electrochemical device for generating a biocidal output solution, said device comprising: a flow-through electrochemical cell comprising an anodic chamber and a cathodic chamber for electrolysing an electrolyte to generate an anolyte solution and a catholyte solution; characterised in that the device further comprises: (i) a reservoir for storing catholyte; and (ii) a hydraulic circuit for recirculating catholyte from the reservoir to the anolyte on start-up of the cell, wherein input of catholyte of a compensating strength to the cell anodic chamber, is arranged so as to optimise the cell anolyte pH to produce a stable output solution at the start of the electrolysis process.Type: ApplicationFiled: February 1, 2013Publication date: September 12, 2013Applicant: TRUSTWATER LIMITEDInventors: David-Lee VAN NIEKERK, Edmond O'REILLY, Kevin KEANE, Eoin CROKE, Michael CAMPION, Brendan KENNEDY
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Publication number: 20130233696Abstract: Source water is treated by mixing a first component selected from the group comprising neutralized phosphonic acid compounds, neutralized phosphonate compounds, neutralized derivatives of phosphorus, neutralized anti-scalent polymers, and mixtures thereof, a second component from the group comprising chlorite salt and chlorate salt is admixed to the mixture of the water and the first component, and water. The water and the first and second components are present in amounts sufficient to form a stable liquid composition in which there is substantially no conversion of the second component to chlorine dioxide.Type: ApplicationFiled: October 4, 2012Publication date: September 12, 2013Inventor: Carl E. Iverson
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Publication number: 20130224314Abstract: The present invention relates to methods of treating or preventing an infection or infectious disease in a mammal, or sanitizing mammalian tissue, or treating or preventing psoriasis in a mammal, comprising topically administering to said mammal an electrolytic acid water comprising free chlorine, wherein: a) from 90% to 99.9% of said free chlorine is present in the form of hypochlorous acid; b) said water has a pH of from 0.5 to 5.0; and c) said water has oxidation reduction potential (ORP) of greater than 1100 mV. The present invention also relates to methods of healing, repair or regeneration of a tissue in a mammal comprising topically administering to said tissue said electrolytic acid water.Type: ApplicationFiled: February 15, 2013Publication date: August 29, 2013Applicant: APR Nanotechnologies s.a.Inventors: Yongge Chen, Roberto De Noni, Giorgio Reiner, Paolo Galfetti
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Patent number: 8518456Abstract: Disclosed are compositions related to a substantially non-cytotoxic chlorine dioxide solution. The solution may be a thickened fluid composition. Also disclosed are methods of making and using a substantially non-cytotoxic thickened fluid compositions or solutions comprising chlorine dioxide solution. An oxidizing composition of reduced irritation is also disclosed.Type: GrantFiled: July 14, 2009Date of Patent: August 27, 2013Assignee: BASF CorporationInventors: Barry Keven Speronello, Frank S. Castellana, Linda Hratko
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Publication number: 20130216293Abstract: This invention relates to extend the benefits of using hypochlorite compounds such as sodium hypochlorite to clean and disinfect articles while reducing or eliminating the side effects of treating an article with a strong oxidant material. The invention relates to a single step process involving mixing of precursor compositions of a suitable hypohalite or hypohalous acid with a solution of a reducing agent. Optionally a boiler may be present in either or both precursor compositions, such that at time of use such active hypohalous acid concentration, in the resulting aqueous mixture remains at a sufficient activity level to effect one or more desired benefits against a target substrate for a desired period of time. The oxidant is substantially consumed by reaction with the reducing agent after the time needed for achieving the desired benefit has passed.Type: ApplicationFiled: November 9, 2012Publication date: August 22, 2013Applicant: The Clorox CompanyInventor: The Clorox Company
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Publication number: 20130216631Abstract: This invention relates to extend the benefits of using hypochlorite compounds such as sodium hypochlorite to clean and disinfect articles while reducing or eliminating the side effects of treating an article with a strong oxidant material. The invention relates to a single step process involving mixing of precursor compositions of a suitable hypohalite or hypohalous acid with a solution of a reducing agent. Optionally a buffer may be present in either or both precursor compositions, such that at time of use such active hypohalous acid concentration in the resulting aqueous mixture remains at a sufficient activity level to effect one or more desired benefits against a target substrate for a desired period of time. The oxidant is substantially consumed by reaction with the reducing agent after the time needed for achieving the desired benefit has passed.Type: ApplicationFiled: November 8, 2012Publication date: August 22, 2013Applicant: The Clorox CompanyInventor: The Clorox Company
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Patent number: 8507011Abstract: A composition and method are described for suppressing or preventing fibrous adhesion formation using a multicomponent aqueous oxychlorine composition. Fibrous adhesions typically form during healing of tissue, for example following a surgical procedure. A multicomponent oxychlorine composition is provided for irrigating the tissue which minimizes post-surgical adhesion formation, the composition containing both chlorine dioxide and chlorite ion, and a complexion thereof. The chlorine dioxide level generally is in an effective range of ClO2 concentration from about 10 ppm to a maximum of about 110 ppm. In a preferred embodiment, a physiological composition is provided in a thickened form to increase retention in the area being treated.Type: GrantFiled: March 19, 2010Date of Patent: August 13, 2013Inventors: Robert D. Kross, Cleva Villanueva
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Publication number: 20130202719Abstract: Pharmaceutical compositions for treating neoplastic disorders and uses thereof are provided. Said pharmaceutical compositions comprise stabilized chlorite solutions (e.g. WFIO) and a fluoropyrimidine, 5-FU, or a 5-FU prodrug (e.g. capecitabine, doxifluridine, UFT, S-1, or BOF-A2). The use of the above stabilized chlorite solution in combination with a fluoropyrimidine dramatically improves the quality of life index (QOL) of a patient undergoing cancer chemotherapy. Cancers that can be treated include cancers of the pancreas, gastrointestinal, head, neck, and breast.Type: ApplicationFiled: January 24, 2013Publication date: August 8, 2013Applicant: NUVO RESEARCH AGInventor: NUVO RESEARCH AG
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Patent number: 8501244Abstract: Described herein are chlorite formulations having a pH between about 7 and about 8.5, wherein the chlorite formulations are substantially free of deleterious non-chlorite components. Described herein are chlorite formulations, including pharmaceutical formulations, which are formulated for systemic, parenteral, or intravenous administration. Described herein are methods of preparing and methods of using the chlorite formulations described herein.Type: GrantFiled: September 29, 2011Date of Patent: August 6, 2013Assignee: Neuraltus Pharmaceuticals, Inc.Inventors: William Boulanger, Arasteh Ari Azhir
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Patent number: 8492419Abstract: Solid formulations for use in water conditioning of circulating reservoirs, processes of preparing same and methods for water conditioning utilizing same are disclosed. The solid formulations combine a sanitizer with a bath salt and/or an odoriferous substance.Type: GrantFiled: April 25, 2007Date of Patent: July 23, 2013Assignee: Bromine Compounds Ltd.Inventors: David Feldman, Theodore M. Fishler, Amiram Groweiss, Aharon Weissman, Gideon Shikolsky, Moshe Link
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Patent number: 8486431Abstract: A method of controlling floating virus infection. The method includes the step of: supplying chlorine dioxide gas into a space where floating virus can be present by a gas concentration which allows the animal to live or stay, but deactivates the virus.Type: GrantFiled: November 27, 2006Date of Patent: July 16, 2013Assignee: Taiko Pharmaceutical Co., Ltd.Inventor: Norio Ogata
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Publication number: 20130177629Abstract: The present application includes liposomes and liposomal compositions that comprise chlorite, chlorate or a mixture thereof entrapped inside the liposome core, methods for their preparation and methods of use, in particular as medicaments.Type: ApplicationFiled: December 21, 2012Publication date: July 11, 2013Applicant: Nuvo Research GmbHInventor: Nuvo Research GmbH
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Publication number: 20130171239Abstract: The instant invention provides preparations comprising an oxidizing antimicrobial agent such as chlorine dioxide and a heterocyclic compound that improves the antibacterial effect of the oxidizing antimicrobial agent preparation. The invention has particular use as an eye care preparation such as an eye drop. The invention further provides methods for reducing bacterial colonization and treating infection.Type: ApplicationFiled: February 25, 2013Publication date: July 4, 2013Applicant: ADVANCED VISION RESEARCH, INC.Inventor: ADVANCED VISION RESEARCH, INC.
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Publication number: 20130164388Abstract: According to one aspect of the invention, a method of converting an oxy halide salt into a halide dioxide in a reaction zone under certain conditions is provided. More specifically, the method includes generating chlorine dioxide from a stable composition comprising an oxy halide salt by introducing said composition to a reducing agent and minimum temperature within the reaction zone. According to another aspect of the invention, a composition for a stable chlorine dioxide precursor comprising an oxy halide salt is provided.Type: ApplicationFiled: February 7, 2013Publication date: June 27, 2013Applicant: SABRE INTELLECTUAL PROPERTY HOLDINGS LLCInventor: SABRE INTELLECTUAL PROPERTY HOLDINGS LLC
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Patent number: 8460717Abstract: The invention relates to an oral care liquid composition in a unique collapsible, air-tight, condiment like package geared toward sterilize and disinfect a toothbrush head. The product is poured onto a toothbrush head removing potentially harmful bacteria and germs from their toothbrush head.Type: GrantFiled: March 14, 2011Date of Patent: June 11, 2013Inventor: Larry Tabb
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Publication number: 20130136805Abstract: The present application relates to foamable compositions and foams comprising stabilized chlorite, including stabilized chlorite solutions such as Oxovasin™, and to medical uses thereof, in particular for wound healing. The foamable compositions comprise at least one foaming agent, stabilized chlorite, water and optionally, a buffering agent.Type: ApplicationFiled: August 12, 2011Publication date: May 30, 2013Inventors: Servet Buyuktimkin, Nadir Buyuktimkin, Edward T. Kisak, John M. Newsam, Dominic King-Smith, Jagat Singh, Rainer Martin
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Patent number: 8445030Abstract: Antiseptic compounds that act as persistent and fast acting antiseptics and disinfectants. The base of these antiseptic actions is CaF2 as the persistent part, preventing the colonization of tissue and nonliving surfaces with microorganisms through the targeted on-demand release of fluorine ions. For fighting heavy contamination and invasion of transient microbes through new application of the solution, fast acting alcohols and toxic solutions have been added in small percentage. They act fast and evaporate fast, leaving the natural protection of skin undamaged and coated with a persistent antiseptic.Type: GrantFiled: September 15, 2010Date of Patent: May 21, 2013Inventors: Fridolin Voegeli, Frank Flechsig, Thomas Flechsig
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Patent number: 8442629Abstract: Provided is to enhance the therapeutic effect of an iontophoretic preparation for treatment of breast cancer or mastitis. An iontophoretic preparation for treatment of breast cancer and/or mastitis containing, as an active ingredient, a nonsteroidal anti-inflammatory analgesic agent and/or an anticancer agent, wherein an electrolyte is topically administered through the nipple part into the mammary gland; subsequently, a donor is applied to the nipple part; and the active ingredient is topically administered through the nipple part into the mammary gland by application of current.Type: GrantFiled: April 17, 2009Date of Patent: May 14, 2013Assignee: Kowa Co., Ltd.Inventors: Kenichi Suzuki, Makoto Kanebako, Toshio Inagi
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Publication number: 20130115259Abstract: The invention relates to polymeric systems for stabilizing, storing and delivering hypohalide salts. One system consists of material coated with two layers: one prepared from polyethylene glycol epoxide and melamine solution and second prepared from inorganic hypohalide salt solution. The material can be fabric, cotton, bamboo, cellulosic materials, blend of cellulosic and synthetic fibres. Antimicrobial materials comprising this system are also described. Another system consists of material containing pre-formed spaces coated with water-polyethylene glycol solution of hypohalide salt and encapsulated by film forming polymer. Hypohalide salts within both systems are in some cases storage stable for at least three months.Type: ApplicationFiled: January 20, 2011Publication date: May 9, 2013Applicant: THE UNIVERSITY OF SOUTH DAKOTAInventors: Yuyu Sun, Zhengbing Cao, Simon Johnston
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Patent number: 8435568Abstract: The present invention provides a method of treating or inhibiting at least one of allergic asthma, allergic rhinitis and atopic dermatitis, or of reducing, inhibiting or treating allergy like symptoms. The methods use compositions comprising chlorite, chloride, chlorate and/or sulfate ions.Type: GrantFiled: July 27, 2012Date of Patent: May 7, 2013Assignee: Nuvo Research AGInventors: Mathias Brosz, Friedrich-Wilhelm Kuhne, Klaus Blaszkiewitz, Thomas Isensee
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Publication number: 20130108575Abstract: This invention provides novel antimicrobial peptides and formulations thereof. The peptides and/or formulations are effective to kill or to inhibit the growth and/or proliferation of various bacteria, yeast, and fungi.Type: ApplicationFiled: October 16, 2012Publication date: May 2, 2013Applicant: C3 JIAN, INC.Inventor: C3 Jian, Inc.
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Publication number: 20130101682Abstract: A composition and methods of its use, the composition comprising: a halogen source, urea, and an additional halogen stabilizer excluding urea, optionally an alkali in a concentration sufficient to provide said composition with a pH of greater than 10; and optionally excluding a stabilized bromine compound from said composition is disclosed. Additionally, a method for reducing biological activity in a process stream is disclosed. The method comprises: providing a composition to a process stream, wherein said composition contains: a halogen, urea, and an additional halogen stabilizer excluding urea, optionally an alkali in a concentration sufficient to provide said composition with a pH of greater than 10; and optionally excluding a stabilized bromine compound from said composition. The invention is also directed to compositions and methods of their use as effective biocidal agents for water streams.Type: ApplicationFiled: November 4, 2011Publication date: April 25, 2013Applicant: NALCO COMPANYInventors: Laura E. RICE, Andrew J. COOPER, Elisa M. LUTH, Wen Li TU
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Publication number: 20130101683Abstract: The invention is directed to compositions and methods of their use as effective biocidal agents for water streams. The composition comprises a halogen source, halogen stabilizers containing a sulfur bearing species and ammonium salts/urea, and an alkali. The sulfur bearing species includes sulfamic acid or its salt equivalent. By having optimized mixing ratio of halogen to stabilizer and that of ammonium salts to sulfamic acid or sulfamate, a synergistic effect occurs which both increases the efficacy of the composition as a biocide and it avoids adverse impacts on other chemicals that are present in the water stream. Best of all the composition is easy to form and easy to introduce into a water stream of concern. Its introduction can be as simple as mixing two containers of reagent prior to introduction to the water process stream.Type: ApplicationFiled: November 4, 2011Publication date: April 25, 2013Applicant: NALCO COMPANYInventors: Wen Li TU, Laura E. RICE, Andrew J. COOPER, Elisa M. LUTH, Yu-mei LU, Jian Kun SHEN
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Patent number: 8420129Abstract: There are provided a chlorine dioxide solution composition whose solute includes dissolved chlorine dioxide and chlorite; and a solution composition encapsulating body including a glass vessel or enameled vessel and the chlorine dioxide solution composition hermetically sealed therein.Type: GrantFiled: January 19, 2009Date of Patent: April 16, 2013Assignee: Taiko Pharmaceutical Co., Ltd.Inventors: Norio Ogata, Takashi Shibata, Kazuhiko Taguchi, Koichi Doi