Saccharomyces Patents (Class 435/255.2)
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Patent number: 11773355Abstract: A system and method for directly transferring fermentation carbon dioxide by-product to a greenhouse are disclosed. A three-way valve receives the carbon dioxide by-product from fermentation vessels in a fermentation facility, and either directs the carbon dioxide by-product to a proximately located greenhouse or diverts the carbon dioxide by-product to the external environment based on greenhouse carbon dioxide concentration levels that are monitored by sensors communicatively coupled to the valve. For example, if the concentration levels are below a threshold, the sensors may transmit a signal to the valve to direct the carbon dioxide by-product to the greenhouse; otherwise, if the concentration levels are at or above the threshold, the carbon dioxide by-product may be diverted to the external environment. The threshold may be a carbon dioxide concentration level determined to be optimal for photosynthetic efficiencies based on a number and/or type of the plants contained within the greenhouse.Type: GrantFiled: March 24, 2020Date of Patent: October 3, 2023Inventor: Mathew Halter
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Patent number: 11634366Abstract: A plant growth enhancer including a source of carbon dioxide, a source of carbohydrate, and source of acid in an amount to provide increased retention of carbon dioxide in the soil. A method of enhancing the growth of plants by applying the plant growth enhancer to the soil containing the plant, the acid increasing retention of the carbon dioxide in the soil, and the plant exhibiting enhanced growth from the combination of the carbon dioxide and carbohydrate.Type: GrantFiled: April 12, 2021Date of Patent: April 25, 2023Assignee: INNOVATIONS FOR WORLD NUTRITION, LLCInventors: Arthur R. Shirley, Jr., Melissa C. Hayes
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Patent number: 11179318Abstract: An object is to provide a cosmetic composition that: has a high soft focus effect, a high skin beautifying effect, and a high moisture retaining effect; is safe; and enables reduction in environmental impact. Yeast cell wall particles retaining shapes of yeast cell walls and having an average particle diameter ranging from 1 to 25 ?m are prepared and blended in a cosmetic composition.Type: GrantFiled: July 16, 2020Date of Patent: November 23, 2021Assignee: NIPPON PAPER INDUSTRIES CO., LTD.Inventors: Tadafumi Hashimoto, Shinji Sugiyama, Shinya Yamaguchi
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Patent number: 10165732Abstract: A system, device and method for delivering CO2 or other gases to plants in fields, orchards, vineyards and the like. A stake with a windbreak structure and gaseous emitters on the upwind side creates a leeward wind eddy surrounding a plant, such as an orchards sapling. This establishes and maintains a gaseous microclimate beneficial to the plant. The device delivers CO2 gas to a plant in an agricultural field, orchard, grove, orchard of the like. The device includes an elongated base adapted to be adjustably placed on the ground a predetermined distance from the plant, upwind of the plant. A wind foil is adjustably connected to the base along its elongated length. The wind foil has a curvilinear geometry with a first face having a generally convex configuration, and a second face having a generally concave configuration. An emitter assembly is disposed on the second face of the wind foil. A gas supply conduit is communicatively connected to the emitter and adapted to be connected to a gas supply.Type: GrantFiled: May 12, 2016Date of Patent: January 1, 2019Inventor: Stewart E. Erickson
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Patent number: 10149891Abstract: A method for improving the performance of a subject or for improving digestibility of a raw material in a feed (e.g. nutrient digestibility, such as amino acid digestibility), or for improving nitrogen retention, or for improving dietary phosphorus absorption and retention, or for improving the efficacy of the phytase, or for improving the subject's resistance to necrotic enteritis or for improving feed conversion ratio (FCR) or for improving weight gain in a subject or for improving feed efficiency in a subject or for modulating (e.g. improving) the immune response of the subject or for reducing populations of pathogenic bacteria in the gastrointestinal tract of a subject, or for reducing nutrient excretion in manure, which method comprising administering to a subject at least one direct fed microbial in combination with a phytase, wherein the phytase is administered to the subject at a dosage of more than about 1500 FTU/kg feed.Type: GrantFiled: September 25, 2015Date of Patent: December 11, 2018Assignee: DUPONT NUTRITION BIOSCIENCES APSInventors: Luis Romero, Peter Plumstead, Luke Barnard
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Patent number: 9751917Abstract: Disclosed is a polynucleotide for cell surface expression. The polynucleotide of the invention comprises a promoter, a secretion signal sequence, a sequence encoding an intended protein, and a sequence encoding a cell surface-localized protein or a cell membrane-binding domain thereof, wherein the promoter is a promoter of a gene encoding the cell surface-localized protein. Provided is a polynucleotide for cell surface expression allowing the production of yeast displaying an enzyme on the cell surface with a high activity.Type: GrantFiled: March 25, 2014Date of Patent: September 5, 2017Assignee: National University Corporation Kobe UniversityInventors: Akihiko Kondo, Tomohisa Hasunuma, Kentaro Inokuma
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Patent number: 9587218Abstract: The present invention relates to novel strains of Saccharomyces that can be produced on a carbonaceous substrate which makes it possible to completely and/or partially replace the use of sugar, and to the use thereof for the production of yeast, in particular on the industrial scale. The invention also relates to a method for producing yeast of the Saccharomyces genus on a carbonaceous substrate which makes it possible to completely or partially replace the use of sugar.Type: GrantFiled: June 13, 2014Date of Patent: March 7, 2017Assignee: Lesaffre et CompagnieInventors: Jean-Luc Fuentes, Georges Rene Marcel Parasie, Emmanuel Poilpre, Anna-Dominique Quipourt-Isnard, Gilles George Albert Stien
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Publication number: 20150132740Abstract: A concentration agent for microorganisms is provided that contains both lanthanum and carbonate. Additionally, articles that include the concentration agent and methods of concentrating a microorganism using the concentration agent are provided.Type: ApplicationFiled: May 23, 2013Publication date: May 14, 2015Inventors: Manjiri T. Kshirsagar, Evan Koon Lun Yuuji Hajime, Andrew W. Rabins
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Patent number: 9005683Abstract: Provided is a method for producing a yeast containing glutamic acid at a high concentration. In the method for culturing a yeast, a yeast in a stationary growth phase is subjected to liquid culture under the conditions that the pH of a liquid medium is 7.5 or higher and lower than 11. After the pH of the liquid medium for the yeast in a stationary growth phase is adjusted to 7.5 or higher and lower than 11, the yeast is further cultured, whereby a yeast with a high glutamic acid content can be produced. In the invention, as the yeast, Saccharomyces cerevisiae or Candida utilis can be used. Therefore, by using the yeast with a high glutamic acid content obtained by the above-said method and the extract obtained by extraction from the yeast, a seasoning composition and a food or drink with a high glutamic acid content can be provided.Type: GrantFiled: October 30, 2009Date of Patent: April 14, 2015Assignee: Asahi Group Holdings, Ltd.Inventors: Ichiro Shibuya, Hiroaki Okano, Yoshitomo Kanaoka, Nobuchika Takesue
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Patent number: 8999701Abstract: Furfural and 5-hydroxymethylfurfural (HMF) are representative inhibitors to ethanologenic yeast generated from biomass pretreatment using dilute acid hydrolysis. Few yeast strains tolerant to inhibitors are available. A novel tolerant strain of Saccharomyces cerevisiae, NRRL Y-50049, having enhanced biotransformation ability to convert furfural to furan methanol (FM), HMF to furan di-methanol (FDM), and is able to produce a normal yield of ethanol as an initial culture.Type: GrantFiled: June 23, 2008Date of Patent: April 7, 2015Assignee: The United States of America, as represented by the Secretary of AgricultureInventor: Zonglin L. Liu
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Patent number: 8986956Abstract: The present invention relates to a method for producing hEGF (human epidermal growth factor) which has the same activity as the wild form, in high concentration and with a high degree of purity. More specifically, the invention relates to an hEGF expression vector comprising a nucleic acid sequence coding for the polypeptide of sequence number 14; a host cell in which the expression vector has been genetically transformed; and a method for producing hEGF, comprising a step in which the expression vector is created and is genetically transformed in yeast from which the KEX1 gene is lacking. Using the method of the present invention, it is possible to produce a large volume of human derived EGF which has the same size and activity as human derived EGF, and this EGF can be used in various ways such as in medicine and cosmetics.Type: GrantFiled: November 4, 2011Date of Patent: March 24, 2015Assignee: Korea Research Institute of Bioscience and BiotechnologyInventors: Jung Hoon Sohn, Jung Hoon Bae, Mi Jin Kim, Hyun Jin Kim, Soon Ho Park, Kwang Mook Lim
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Publication number: 20150079648Abstract: A stabilized biomass and a method of producing a stabilized biomass is disclosed. The biomass has active matter containing carbon atoms having an average oxidation state, inactive matter, a biological catalyst having a fermentation organism capable of converting the active matter into a renewable material, and water. The biomass has not been milled. The biomass is suitable for use in the production of renewable materials, such as ethanol.Type: ApplicationFiled: September 19, 2014Publication date: March 19, 2015Inventor: Jacob R. Borden
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Patent number: 8980617Abstract: Novel strains of yeast and methods for improved ethanol production utilizing the yeast strains are disclosed. In particular, the novel yeast strains Saccharomyces cerevisae YE1358 and YE1615 provide for increased fermentation temperature tolerance, as well as tolerance to increased levels of glucose and ethanol, and thereby provide increased ethanol production as compared to ethanol industry standard strains of Saccharomyces cerevisae. The novel yeast strains also generate decreased residual glucose than the ethanol industry standard yeasts.Type: GrantFiled: February 8, 2013Date of Patent: March 17, 2015Assignee: Pioneer Hi Bred International IncInventors: Kimberly J. Forrester, William Rutherford, Douglas Haefele
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Patent number: 8969065Abstract: A high flux in conversion of pyruvate to acetolactate was achieved in yeast through expression of acetolactate synthase in the cytosol in conjunction with reduction in pyruvate decarboxylase activity. Additional manipulations to improve flux to acetolactate are reduced pyruvate dehydrogenase activity and reduced glycerol-3-phosphate dehydrogenase activity. Production of compounds having acetolactate as an upstream intermediate benefit from the increased conversion of pruvate to acetolactate in the described strains.Type: GrantFiled: January 22, 2014Date of Patent: March 3, 2015Assignee: Butamax Advanced Biofuels LLCInventors: Larry Cameron Anthony, Lori Ann Maggio-Hall
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Publication number: 20150037845Abstract: The present disclosure relates to mutant thermostable glycosyl hydrolases family 7 enzymes, including mutant Trichoderma reesei endoglucanase I. In particular, the present disclosure relates to mutant thermostable enzymes, compositions containing the enzymes, and methods of use thereof.Type: ApplicationFiled: August 11, 2011Publication date: February 5, 2015Applicant: The Regents of the University of CaliforniaInventors: Harshal Akshay Chokhawala, Tae-Wan Kim, Harvey W. Blanch, Douglas S. Clark
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Publication number: 20140342435Abstract: The present invention relates to novel strains of Saccharomyces that can be produced on a carbonaceous substrate which makes it possible to completely and/or partially replace the use of sugar, and to the use thereof for the production of yeast, in particular on the industrial scale. The invention also relates to a method for producing yeast of the Saccharomyces genus on a carbonaceous substrate which makes it possible to completely or partially replace the use of sugar.Type: ApplicationFiled: June 13, 2014Publication date: November 20, 2014Inventors: Jean-Luc Fuentes, Georges Rene Marcel Parasie, Emmanuel Poilpre, Anna-Dominique Quipourt-Isnard, Gilles George Albert Stien
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Patent number: 8835152Abstract: Compositions of peptides and surface-active agents are described, as are methods of making and using such compositions. The compositions are capable of affecting metabolic rates in biological systems, and to accelerate nutrient uptake without a concomitant increase in biofilm production.Type: GrantFiled: December 4, 2012Date of Patent: September 16, 2014Assignee: Advanced Biocatalytics CorporationInventor: Carl W. Podella
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Patent number: 8815548Abstract: The invention features methods for producing isoprene from cultured cells using a feedback-resistant mevalonate kinase polypeptide, such as an archaeal mevalonate kinase polypeptide. The resulting isoprene compositions may have increased yields and/or purity of isoprene.Type: GrantFiled: December 28, 2012Date of Patent: August 26, 2014Assignees: Danisco US Inc., The Goodyear Tire & Rubber CompanyInventors: Zachary Q. Beck, Anthony R. Calabria, Michael C. Miller, Alex T. Nielsen, Dmitrii V. Vaviline
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Patent number: 8790908Abstract: The present invention relates to novel strains of Saccharomyces that can be produced on a carbonaceous substrate which makes it possible to completely and/or partially replace the use of sugar, and to the use thereof for the production of yeast, in particular on the industrial scale. The invention also relates to a method for producing yeast of the Saccharomyces genus on a carbonaceous substrate which makes it possible to completely or partially replace the use of sugar.Type: GrantFiled: March 13, 2009Date of Patent: July 29, 2014Assignee: Lesaffre et CompagnieInventors: Jean-Luc Fuentes, Georges Rene Marcel Parasie, Emmanuel Poilpre, Anne-Dominique Quipourt-Isnard, Gilles Georges Albert Stien
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Publication number: 20140206048Abstract: The present invention provides compositions and methods for the use of oil-containing materials as feedstocks for the production the bioproducts by biofermentation. In one preferred embodiment, surfactants are not used in compositions and the methods of the invention. In one preferred embodiment the oil-containing feedstocks are the by-products of other industrial processes including microbial, plant and animal oil processing.Type: ApplicationFiled: January 22, 2014Publication date: July 24, 2014Applicant: Glycos Biotechnologies, Inc.Inventors: Daniel J. Monticello, Ryan Black, Paul Campbell
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Patent number: 8771676Abstract: The present invention provides an agrochemically active microbial formulation comprising a combination of an agrochemically active microbe with a specified ester compound and a surfactant, the formulation exhibiting a stable pest controlling effect with no harmful effect on a plant and having highly stable viability of the agrochemically active microbe.Type: GrantFiled: June 22, 2007Date of Patent: July 8, 2014Assignee: Sumitomo Chemical Company, LimitedInventors: Shinya Kimura, Yoshiki Takashima, Takeshi Maruyama
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Patent number: 8765404Abstract: Some aspects of this invention relate to methods useful for the conversion of a carbon source to a biofuel or biofuel precursor using engineered microbes. Some aspects of this invention relate to the discovery of a key regulator of lipid metabolism in microbes. Some aspects of this invention relate to engineered microbes for biofuel or biofuel precursor production.Type: GrantFiled: March 2, 2011Date of Patent: July 1, 2014Assignee: Massachusetts Institute of TechnologyInventors: Gregory Stephanopoulos, Syed Hussain Imam Abidi
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Publication number: 20140162936Abstract: The present invention relates to a polypeptide binding to a chymase (EC 3, 4, 21,39), wherein the polypeptide comprises or consists of an amino acid sequence selected from the group consisting of: (a) GVTLFVALYDY(X1)A(X2)(X3)(X4)(X5) (X6)LSFHKGEKFQIL(X7 (X8)(X9)(X10) (X11)(X12)G(X13)(X14)WEARSLTTGETGYIPSNYVAPVDSIQ (SEQ ID NO: 1), wherein (X1) is R, N, Q, E, K, H, S, T, C, or D; (X2) is E, T, D, Q, L, P, A, S, C, M, N, E, G, A, V or I; (X3) is R, T, H, N, K, S, C, N or Q; (X4) is S, W, T, C, N, Q, For Y; (X5) is T, H, L, F, C, S, M, N, Q, R, K, G, A, V, I, P, Y or W; (X6) is D, Q, H, E, S, T, C, N, R or K; (X7) is D, N, R, E, Q, S, T, C, K or D; (X8) is M, W, G, F, A, S, T, C, S, N, Q, Y, V, L, I or P; (X9) is T, H, S, D, C, N, Q, R, K, E or absent; (X10) is V, T, Q, G, A, L, I, P, S, C, M, N or absent; (X11) is P, A, D, G, K, V, L, I, E, R, M, H or absent; (X12) is N, V, P, I, E, T, S, A, G, L, C, M, Q or D; (X13) is D, E, T, P, G, A, V, L, I, S, C, M, N or Q, and (X14) is W, Y, L, G, A, V, I, P, M, or F; (b)Type: ApplicationFiled: April 24, 2012Publication date: June 12, 2014Applicant: COVAGEN AGInventors: Simon Brack, Sarah Batey, Dragan Grabulovski, Julian Bertschinger, Daniel Schlatter, Jörg Benz, David Banner, Michael Hennig
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Patent number: 8735138Abstract: The present invention relates to methods for producing Saccharomyces strains that are capable of growth on xylose as a sole carbon source at a desired growth rate (such as at least one generation per 48 hours), strains made by such methods, and Saccharomyces strains that grow at a growth rate of at least one generation per 48 hours using xylose as a sole carbon source for growth made by non-recombinant methods.Type: GrantFiled: September 16, 2009Date of Patent: May 27, 2014Assignee: Microbiogen Pty LtdInventors: Philip John Bell, Paul Victor Attfield
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Patent number: 8735338Abstract: Surfactant-containing compositions are described which include a protein component that has the effect of improving the surface-active properties of the surfactants contained in the compositions. The surfactant-containing compositions having the protein component demonstrate significantly lower critical micelle concentrations (CMC), reduced surface tensions, and reduced interfacial tensions than do comparable compositions having no protein component. In addition, the surfactant-containing compositions having the protein component has the effect of converting greasy waste contaminants to surface active materials.Type: GrantFiled: May 29, 2012Date of Patent: May 27, 2014Assignee: Advanced Biocatalytics Corp.Inventors: John W. Baldridge, Carl W. Podella
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Publication number: 20140120601Abstract: The present invention comprises compositions and methods for enhancing biological processes, such as plant growth or bioremediation. For example, the present invention comprises compositions and methods for effectively remediating chemical and organic wastes and reducing the environmental risk from manure, septic, sewage, oil pollution, and other contaminants.Type: ApplicationFiled: January 12, 2012Publication date: May 1, 2014Applicant: INOCUCORInventors: Margaret Bywater-Ekegard, Ananda Fitzsimmons
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Patent number: 8697406Abstract: Sugars comprising the monosaccharides glucose and fructose, and the disaccharides sucrose and mannose are catalytically converted to ethanol in a sulfate fortified acid medium in the presence of transition metal compounds possessing a degree of symmetry. This is not a fermentation process but is a catalytic chemical process where conversion efficiency is improved by saturating the acidic reaction mixture with inorganic sulfate salts to reduce competitive reactions. Ethanol formed during the reaction is removed by distillation facilitating a continuous process.Type: GrantFiled: August 16, 2010Date of Patent: April 15, 2014Inventor: Melvin Keith Carter
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Patent number: 8697425Abstract: The present invention relates to a composite yeast for high concentration alcohol fermentation, which includes thermostable Saccharomyces cerevisiae, acid protease, phytase, cellulose, ?-glucanase, and pectinase, and is suitable for the high concentration alcohol fermentation for various raw materials. In addition to normal fermentation, the composite yeast of the present invention can degrade the raw materials, increase the nutrient ingredients in the mash, promote the growth of yeast and provide stress tolerance protection.Type: GrantFiled: December 30, 2005Date of Patent: April 15, 2014Assignee: Angel Yeast Co., Ltd.Inventors: Xuefeng Yu, Zhihong Li, Minghua Yu, Juan Yao, Zhijun Li, Daiwu Liu
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Patent number: 8679786Abstract: The invention relates to a method for the preparation of a copper-enriched biomass, comprising, in a first step, culturing Saccharomyces cerevisiae yeast cells in a liquid nutrient medium comprising a carbon source, a nitrogen source, at least one amino acid and a copper salt, so as to obtain copper-enriched yeast biomass in the form of a Cu-GSH complex, wherein the intracellular content of Cu-GSH is higher than 1% dw and, in a second step, separating the copper-enriched yeast biomass from the nutrient liquid medium. Two strains of Saccharomyces cerevisiae are described, designated as SA 221 BM and SA 586 BM, respectively (accession numbers DSM 21530 and DSM 21531, deposited with the DSMZ on Jun. 6, 2008), which have the ability to accumulate particularly high levels of intracellular copper. Moreover, the invention relates to the copper-enriched yeast biomass obtainable by the method of the invention, which has an intracellular Cu-GSH content higher than 1% dw, and its use in cosmetic and probiotic products.Type: GrantFiled: July 15, 2009Date of Patent: March 25, 2014Assignee: Bioman S.R.L.Inventors: Matilde Manzoni, Manuela Silvia Rollini, Alberto Benedetti
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Publication number: 20140065172Abstract: The present invention relates to a delivery system that comprises a conjugate that facilitates the delivery of a compound such as a biologically-active macromolecule, a nucleic acid or a peptide in particular, into a cell. The present invention also relates to said conjugate for delivery of a compound, such as a biologically-active macromolecule, a nucleic acid or a peptide, into a cell. The present invention further relates to a pharmaceutical composition comprising said conjugate and to its use. The present invention also relates to a method of delivering a compound to a cell or an organism, preferably a patient.Type: ApplicationFiled: January 26, 2012Publication date: March 6, 2014Inventors: Christophe J. Echeverri, Birte Sönnichsen, Reinhard Wähler, Mike Werner Helms, Brian S. Sproat
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Patent number: 8647870Abstract: A biological photoreceptor, which is a directly light-controlled ion channel, including (i) an apoprotein and (ii) a light-sensitive polyene covalently bound to the apoprotein, the polyene interacting with the apoprotein and functioning as a direct light-sensitive gate.Type: GrantFiled: April 23, 2012Date of Patent: February 11, 2014Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V.Inventors: Peter Hegemann, Georg Nagel, Ernst Bamberg
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Patent number: 8647848Abstract: The invention relates to the enzymatic synthesis of sphingolipids and compositions that contain sphingolipids from lysosphingolipids and carbonic esters, and to cosmetic, dermatological or pharmaceutical formulations containing said sphingolipids or compositions.Type: GrantFiled: May 22, 2009Date of Patent: February 11, 2014Assignee: Evonik Goldschmidt GmbHInventors: Frank Hollmann, Oliver Thum, Christoph Toelle, Angelo Provinzano, Cornelis Gerrit Nijs Korevaar
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Patent number: 8642259Abstract: The present invention relates to methods for identifying substances capable of influencing the activity of a target molecule affecting cellular proliferation.Type: GrantFiled: July 23, 2003Date of Patent: February 4, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: Sabine Gratzer, Meltsje De Hoop, Bernhard Mai
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Publication number: 20140017767Abstract: The present invention relates to microbial inocula and in particular to standardised inocula for producing reference cultures of microorganisms. The invention has been developed primarily for use as a solid, disc-shaped, inoculum and will be described hereinafter with reference to this application. However, it will be appreciated that the invention is not limited to this particular field of use.Type: ApplicationFiled: June 21, 2013Publication date: January 16, 2014Applicant: AMS Laboratories Pty LtdInventors: Paul PRISCOTT, Yi-hong WANG
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Publication number: 20130344197Abstract: The present invention relates to novel broad spectrum strains of baker's yeast, i.e. yeast strains that are effective on both dough known as unsweetened dough and dough known as sweet dough.Type: ApplicationFiled: June 20, 2013Publication date: December 26, 2013Inventors: Jean-Charles Bartolucci, Didier Colavizza, Melanie Legros, Georges Pignede
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Publication number: 20130330439Abstract: The invention relates to compositions for use as silage inoculants comprising a yeast strain, one or more bacterial stains, and a suitable carrier. The invention also relates to methods of improving livestock animal silage and meat and milk performance of a livestock animal.Type: ApplicationFiled: June 11, 2013Publication date: December 12, 2013Inventors: Fredric Owens, Brenda Smiley
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Publication number: 20130295620Abstract: A method for producing a strain of Saccharomyces cerevisiae with introduced genes coding for xylose reductase, xylitol dehydrogenase and xylulokinase and with improved ethanol production, improved xylose conversion and reduced xylitol production is described. The method comprises culturing the cells in a repetitive batch series in a medium at a xylose concentration of about 15-25 g/l and at a temperature of about 28-32° C., and thereafter lowering the xylose concentration in at least one step at a temperature of about 28-32° C. to obtain an increased selection pressure for improved xylose fermentation,improved ethanol production and reduced xylitol production, and continuing the culturing of the cells in said repetitive batch series. Further, strains of Saccharomyces cerevisiae obtained by the method according to the invention are described.Type: ApplicationFiled: November 15, 2011Publication date: November 7, 2013Applicant: SCANDINAVIAN TECHNOLOGY GROUP ABInventors: Eva Albers, Lisbeth Olsson, Rakesh Koppram
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Publication number: 20130288340Abstract: An object of the present invention is to provide a microorganism which is novel at the elemental composition level, and to provide a technique for providing such a microorganism. The present inventor has succeeded in causing a microorganism to efficiently contain a non-essential element by decreasing the content of an essential nutrient source for the microorganism, a C source, an N source, a P source, or an S source, and by adding an X compound containing the non-essential element as a constitutive element in a manner to make up for the decreased amount, and then culturing the microorganism.Type: ApplicationFiled: September 5, 2011Publication date: October 31, 2013Applicants: PARA MICROBIOS LABORATORIES LLCInventor: Yoshitake Tanaka
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Patent number: 8569039Abstract: A biologically pure culture of Saccharomyces cervisiae GP-01, and a method for producing Saccharomyces Cervisiae GP-01 which is ethanol-resistant and obtained by protoplast fusing Saccharomyces Cerevisiae (KCTC 7904) and Candida Ethanolica (KCTC 7181). Further, the present invention provides yeast containing the high content of organic bio-germanium (the yeast Ge-32K) and a method for producing the yeast Ge-32K, comprising adding the yeast GP-01 into a solution of sodium metagermanate (Na2GeO3) at the volume ratio of 1:0.5˜2; adding 0.1˜0.4 wt % of surfactant, instead of germanium dioxide as used in the prior arts; and cultivating an obtained broth. The obtained yeast Ge-32K contains the higher content of the organic bio-germanium than the conventional yeast as produced by using germanium dioxide.Type: GrantFiled: December 31, 2008Date of Patent: October 29, 2013Assignee: Geranti Pharm Ltd.Inventors: Tsang-Uk Sohn, Dae-Heoun Baek
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Publication number: 20130273587Abstract: Provided are compositions and methods related to heme transporters and high-throughput methods of identifying agents that can modulate heme transporters. An approach for identifying a modulator of a eukaryotic heme transporter involves adding a toxic heme analog and at least one test agent to a culture of cells, wherein the cells express a recombinant heterologous eukaryotic heme transporter. The cells are incubated with the toxic heme analog and the test agent for a period of time. A change in toxic effect of the toxic heme analog relative to a control is indicative that the test agent is a modulator of the eukaryotic heme transporter. Heme transporter agonists and antagonists can be identified. Also provided is a cell culture comprising a plurality of cells which express a recombinant heterologous eukaryotic heme transporter. The plurality of cells are divided into a plurality of reaction chambers, each of which may contain a test agent, and may further contain a toxic heme analog.Type: ApplicationFiled: April 17, 2013Publication date: October 17, 2013Applicant: University of Maryland, College ParkInventors: Iqbal Hamza, Richard Bruick
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Publication number: 20130260441Abstract: Systems, compositions, and methods for the bioremediation of a contaminant contained within a contaminated region. The systems, compositions, and methods may include supplying a first bioremediation formulation that includes an ion exchange resin to a first treatment zone that is associated with the contaminated region. The systems, compositions, and methods further may include supplying a second bioremediation formulation that includes a high-mobility oxidant, a low-mobility oxidant, and a nutrient material to a second treatment zone that is associated with the contaminated region. The systems, compositions, and methods also may include a kit of bioremediation formulations that includes the first bioremediation formulation and the second bioremediation formulation and is to be utilized during the bioremediation of the contaminated region.Type: ApplicationFiled: August 2, 2012Publication date: October 3, 2013Applicant: Bioremediation Specialists, LLCInventor: Troy John Fowler
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Patent number: 8530226Abstract: The invention relates to a yeast cell producing isobutanol, characterized in that the cell has an increased metabolic flow of material from pyruvate and acetolactate, 2,3-dihydroxy isovalerate, 2-ketoisovalerate, isobutyraldehyde to isobutanol, in that at least one of the genes coding the enzymes, which are involved in this conversion, is over-expressed, and without any of said genes being heterologous to said yeast cell, and to a method for the production of isobutanol using yeast cells, comprising the provision of the yeast cells according to the invention, and bringing the yeast cell into contact with a fermentable carbon source.Type: GrantFiled: February 19, 2009Date of Patent: September 10, 2013Assignee: Butalco GmbHInventors: Gunter Festel, Eckhard Boles, Christian Weber, Dawid Brat
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Patent number: 8518683Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce ethanol and/or butanol, e.g., by fermentation.Type: GrantFiled: July 20, 2012Date of Patent: August 27, 2013Assignee: Xyleco, Inc.Inventors: Marshall Medoff, Thomas Craig Masterman
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Publication number: 20130189298Abstract: The present invention provides an isolated Saccharomyces pastorianus No 54, which is found to be effective in regulating blood glucose levels and fat or its related disease. Therefore, not only could it control the high blood sugar levels in type 1 diabetic patients, but also it would help to control both of the high blood glucose levels and fat of type 2 diabetic patients.Type: ApplicationFiled: March 13, 2012Publication date: July 25, 2013Applicant: GUO-JANE TSAIInventors: GUO-JANE TSAI, Chien-Hui Wu
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Publication number: 20130183732Abstract: This disclosure provides compositions and methods for culturing microorganisms. The disclosure includes mixtures of different microorganisms, especially mixtures of cyanobacteria with fermentative microorganisms. For example, methods and compositions related to co-cultures of yeast and cyanobacteria are provided. Also provided are feedstocks derived from cyanobacteria as well as methods of making such feedstocks and methods of culturing microorganisms in such feedstocks.Type: ApplicationFiled: December 19, 2012Publication date: July 18, 2013Applicant: HELIOBIOSYS, INC.Inventor: HELIOBIOSYS, INC.
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Publication number: 20130171707Abstract: [Problem] To provide an alcoholic fermentation yeast having resistance to limonene, which is a fermentation inhibitor, and a method for producing ethanol using the alcoholic fermentation yeast. [Solution] An alcoholic fermentation yeast Saccharomyces cerevisiae (Deposition No. NITE BP-890), which has resistance to limonene and can grow in the presence of limonene at a concentration of 0.1-0.5 wt %, and a method for producing ethanol using the alcoholic fermentation yeast.Type: ApplicationFiled: August 4, 2011Publication date: July 4, 2013Applicants: Ehime Prefecture, Nippon Steel Engineering Co., Ltd.Inventors: Natusuki Maekawa, Yasuhiko Katoh, Takafumi Kiuchi, Praneetrattananon Suthasinee, Shinji Okamoto, Kazuko Hirayama, Syunsuke Miyaoka, Hideaki Tadanobu, Masahiko Sudo
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Patent number: 8476058Abstract: The invention relates to novel yeast strains, to the yeasts resulting from these strains, to a composition containing at least one Saccharomyces cerevisiae yeast and/or derivatives of a yeast having a particular interest as a food additive and/or probiotic and/or functional food and/or neutraceutic and/or functional ingredient and/or cosmeceutical and/or pharmaceutical active agent. The invention also relates to the use of the same in human and/or animal nutrition, or for the treatment or prevention of inflammatory diseases.Type: GrantFiled: December 12, 2008Date of Patent: July 2, 2013Assignees: Lesaffre et Compagnie, Universite du Droit et de la Sante Lille 2, Universite d 'Auvergne Clermont 1Inventors: Jean-Luc Simon, Georges Pignede, Pascal Vandekerckove, Pierre Desreumaux, Daniel Poulain, Arlette Darfeuille-Michaud, Adeline Sivignon
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Publication number: 20130149760Abstract: Novel strains of yeast and methods for improved ethanol production utilizing the yeast strains are disclosed. In particular, the novel yeast strains Saccharomyces cerevisae YE1358 and YE1615 provide for increased fermentation temperature tolerance, as well as tolerance to increased levels of glucose and ethanol, and thereby provide increased ethanol production as compared to ethanol industry standard strains of Saccharomyces cerevisae. The novel yeast strains also generate decreased residual glucose than the ethanol industry standard yeasts.Type: ApplicationFiled: February 8, 2013Publication date: June 13, 2013Applicant: PIONEER HI BRED INTERNATIONAL, INC.Inventor: PIONEER HI BRED INTERNATIONAL, INC.
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Patent number: 8450099Abstract: An object of the present invention is to provide a process for conveniently and efficiently producing high purity thioredoxin from yeast. In the production of thioredoxin using yeast, thioredoxin is produced through the following steps (i) to (iii): (1) culturing the yeast; (2) stressing the yeast obtained in step (1) to cause a release of thioredoxin from a cell of the yeast; and (3) collecting the thioredoxin released from the yeast cell.Type: GrantFiled: September 15, 2006Date of Patent: May 28, 2013Assignees: Kyoto University, Redox Bioscience Inc., Kizakura Co., Ltd.Inventors: Junji Yodoi, Yoshiharu Inoue, Shingo Izawa, Hiroshi Masutani, Kazuo Murata, Shogo Tamasu
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Publication number: 20130065270Abstract: The present invention relates to methods for producing Saccharomyces strains that are capable of growth on xylose as a sole carbon source at a desired growth rate, (such as at least one generation per 48 hours), strains made by such methods, and Saccharomyces strains that grow at a growth rate of at least one generation per 48 hours using xylose as a sole carbon source for growth made by non-recombinant methods.Type: ApplicationFiled: August 20, 2012Publication date: March 14, 2013Applicant: Microbiogen Pty Ltd.Inventors: Philip John Livingstone Bell, Paul Victor Attfield