The Hetero Ring Has Exactly 15 Ring Carbons Patents (Class 514/30)
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Publication number: 20130216483Abstract: A method of remotely treating an animal including launching a delivery system at the animal, wherein the delivery system comprises a dosage projectile adapted to deliver a biologically active agent to an animal substantially without piercing the skin of the animal and containing a biologically active agent and a transdermal carrier in liquid or gel form, wherein the agent and the carrier are encapsulated in one or more encapsulating agents, and wherein the encapsulating agents forms a frangible shell; impacting the projectile on the animal to release the biologically active agent and the transdermal carrier from the frangible shell substantially without piercing the skin of the animal; and delivering the biologically active agent to the animal, wherein the transdermal carrier facilitates passage of the biologically active agent across the skin of the animal to provide treatment to the animal.Type: ApplicationFiled: March 15, 2013Publication date: August 22, 2013Applicant: SMARTVET PTY LTD.Inventor: SmartVet Pty Ltd.
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Publication number: 20130209381Abstract: Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.Type: ApplicationFiled: March 27, 2013Publication date: August 15, 2013Applicant: Galderma S.A.Inventor: Galderma S.A.
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Publication number: 20130210623Abstract: The present invention provides pesticidal mixtures comprising a component A and a component B, wherein component A is an enantiomeric mixture of a compound of formula I that is enantiomerically enriched for the S enantiomer (Formula I) wherein the symbol * indicates the chiral centre; wherein A1, A2, R1, R2, R4, R5, R6 and p are as defined in claim 1, and component B is a compound as defined in claim 1. The present invention also relates to methods of using said mixtures for the control of plant pests.Type: ApplicationFiled: June 8, 2011Publication date: August 15, 2013Applicant: SYNGENTA CROP PROTECTION LLCInventors: Jerome Yves Cassayre, Elvira Molitor
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Patent number: 8507453Abstract: A novel compound that has antimicrobial activity against penicillin-resistant Streptococcus pneumoniae, and an anti-penicillin resistant pneumococci agent that includes the compound as an active ingredient are provided. Thus, an anti-penicillin resistant pneumococci agent is provided that includes as an active ingredient a compound represented by the following formula (I) or a pharmacologically acceptable salt thereof, or hydrates thereof: wherein, in the formula (I), R represents any one of a halogen atom, an azido group, Ra-Wa-, Rb-Wb-, Rc-Wc-, and RdRd?N—.Type: GrantFiled: September 23, 2011Date of Patent: August 13, 2013Assignee: Microbial Chemistry Research FoundationInventors: Toshiaki Miyake, Yoshiaki Takahashi
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Publication number: 20130203590Abstract: Mixtures comprising cis-jasmone and an agrochemical active ingredient are useful in agriculture.Type: ApplicationFiled: March 23, 2011Publication date: August 8, 2013Applicant: SYNGENTA CROP PROTECTION LLCInventors: Stephen Wilson Skillman, Christoph Grimm, Ulrich Johannes Haas
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Publication number: 20130203692Abstract: This invention relates to oral veterinary compositions for combating ectoparasites and endoparasites in animals, comprising at least one systemically-acting active agent in combination with a pharmaceutically acceptable carrier. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.Type: ApplicationFiled: January 31, 2013Publication date: August 8, 2013Applicant: MERIAL LIMITEDInventors: Mark David Soll, Diane Larsen, Susan Mancini Cady, Peter Cheifetz, Izabela Galeska
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Publication number: 20130196852Abstract: The invention provides a method for preparing an improved composition comprising at least one active agent and at least one solid carrier material, wherein the active agent is dispersed through the carrier material in nano-disperse form, which method comprises the steps of: (a) forming a liquid mixture comprising the active agent, the carrier material, a stabilizing agent, a first solvent for the active agent and the stabilizing agent and, a second solvent for the carrier material, and (b) drying the liquid mixture to remove the first and second solvents to obtain a substantially solvent-free nano-dispersion of the active agent with the stabilising agent in the carrier material, wherein the stabilizing agent is capable of stabilizing the active agent in the liquid mixture during drying and in a resultant liquid nano-dispersion of the improved composition.Type: ApplicationFiled: October 4, 2011Publication date: August 1, 2013Applicant: IOTA NANOSOLUTIONS LIMITEDInventors: Steven Paul Rannard, David Duncalf, Alison Jayne Foster, James Long, Dong Wang
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Publication number: 20130189228Abstract: This invention provides compounds of Formula 1, N-oxides and suitable salts thereof wherein R1 is Me, Cl, Br or F; R2 is F, Cl, Br, C1-C4 haloalkyl or C1-C4 haloalkoxy; R3 is F, Cl or Br; R4 is H; C1-C4 alkyl, C3-C4 alkenyl, C3-C4 alkynyl, C3-C5 cycloalkyl, or C4-C6 cycloalkylalkyl, each optionally substituted with one substituent selected from the group consisting of halogen, CN, SMe, S(O)Me, S(O)2Me, and OMe; R5 is H or Me; R6 is H, F or Cl; and R7 is H, F or Cl. Also disclosed are methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of Formula 1, an N-oxide thereof or a suitable salt of the compound (e.g., as a composition described herein).Type: ApplicationFiled: March 11, 2013Publication date: July 25, 2013Applicant: E I DU PONT DE NEMOURS AND COMPANYInventor: E I DU PONT DE NEMOURS AND COMPANY
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Publication number: 20130190260Abstract: The novel active compound combinations of extracts from seeds of the neem tree and the active compounds of groups (B) to (F) listed in the description have very good insecticidal and acaricidal properties.Type: ApplicationFiled: March 11, 2013Publication date: July 25, 2013Applicant: BAYER CROPSCIENCE AGInventor: BAYER CROPSCIENCE AG
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Patent number: 8491928Abstract: Compositions and nanoemulsions containing lipid nanocapsules dispersed in a hydrophilic phase, such nanocapsules including at least one avermectin compound, are useful for the treatment of dermatological pathologies, e.g., rosacea.Type: GrantFiled: October 9, 2012Date of Patent: July 23, 2013Assignee: Galderma S.A.Inventors: Claire Mallard, Lara Baudonnet
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Publication number: 20130178434Abstract: A method of treating otitis externa is disclosed. The method includes topically applying an otic composition containing an effective amount of one or more macrocyclic lactone compounds, including avermectin compounds or milbemycin compounds and a pharmaceutically acceptable carrier into the external auditory canal and the auricle of an affected ear of an individual suffering from otitis externa.Type: ApplicationFiled: October 14, 2011Publication date: July 11, 2013Applicant: GALDERMA S.A.Inventors: L. Dean Parks, Jeffrey D. Parks
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Publication number: 20130178432Abstract: The present invention relates to ivermectin formulations for administration to pet and domestic animals. These formulations provide long term protection against Dirofilaria parasites, without the risks for secondary adverse of conventional formulations. Preferred formulations are collars, collar strips, or medallions, attachments for collars, ear tags, bands which are affixed to limbs or parts of the body, adhesive strips and films, and peel-off films, or spot-on or pour-on forms which are administered at least twice a year up to around once a year.Type: ApplicationFiled: July 29, 2011Publication date: July 11, 2013Applicant: CEVA SANTE ANIMALEInventors: Patrick Forget, Vassilios Kaltsatos, Stephan Warin
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Publication number: 20130178433Abstract: A method of treating hemorrhoids is disclosed. The method includes locally administering a composition including an effective amount of one or more macrocyclic lactone compounds, including avermectin compounds, milbemycin compounds, or mixture thereof and a pharmaceutically acceptable carrier to the affected anorectal region of an individual suffering from hemorrhoid.Type: ApplicationFiled: October 14, 2011Publication date: July 11, 2013Applicant: GALDERMA S.A.Inventors: L. Dean Parks, Jeffrey D. Parks
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Publication number: 20130172281Abstract: The present invention further relates to ivermectin, most preferably formulated as an implant for administration of pet and domestic animals. These formulations provide long term protection against Dirofilaria parasites, without the risks for secondary adverse events of conventional formulations. Preferred formulations are implants and are administered at least twice a year, once a year, or at least once in 18 months, up to 24 months.Type: ApplicationFiled: July 29, 2011Publication date: July 4, 2013Applicant: CEVA SANTE ANIMALEInventors: Patrick Forget, Vassilios Kaltsatos, Stephan Warin
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Publication number: 20130172282Abstract: A method of treating herpes simplex virus infection or varicella zoster virus infection is disclosed. The method includes topically applying a composition containing an effective amount of one or more macrocyclic lactone compounds, including avermectin compounds or milbemycin compounds and a pharmaceutically acceptable carrier to the affected area of an individual suffering from herpes simplex virus infection or varicella zoster virus infection.Type: ApplicationFiled: October 14, 2011Publication date: July 4, 2013Applicant: GALDERMA S.A.Inventors: L. Dean Parks, Jeffrey D. Parks
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Patent number: 8475828Abstract: A medical device that includes at least one antibiotic in a macromolecular substance that swells upon contact with a solvent. Also, a method for preparing an antibiotic-containing medical device that involves contacting a medical device having at least a portion of the surface formed from a swellable macromolecular substance, with a solvent that swells the macromolecular substance, contacting the swollen macromolecular substance with at least one antibiotic, and removing the solvent from the swollen macromolecular substance.Type: GrantFiled: September 21, 2011Date of Patent: July 2, 2013Assignee: Covidien LPInventors: Kenichi Amano, Yoshimi Akaike
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Patent number: 8470788Abstract: Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.Type: GrantFiled: June 21, 2012Date of Patent: June 25, 2013Assignee: Galderma S.A.Inventors: Vincent Manetta, Gary R. Watkins
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Patent number: 8466115Abstract: The invention recites spirocyclic isoxazoline derivatives of Formula (V.1), Formula (V.2), Formula (V.1.1), and Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, processes for making, and their use as a parasiticide in an animal. The variables A, V, Z, W1, W2, W3, W, Y, X, R1a, R1b, R1c, R2, R3, R4, n, and “” are as described herein.Type: GrantFiled: March 8, 2012Date of Patent: June 18, 2013Assignee: Zoetis LLCInventors: Michael Curtis, Sanjay Menon, Valerie A. Vaillancourt, Nathan Anthony Logan Chubb, Denis Billen, Sean David William Greenwood, Timothy Lee Stuk
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Publication number: 20130150316Abstract: The present invention relates to levocarrimycin, its pharmaceutical compositions, preparation methods and application. Levocarrimycin is a mixture of isovalerylspiramycin III, II and I as main components and contains some isobutyrylspiramycin III and II, butyrylspiramycin III and II, propionylspiramycin III and II, as well as acetylspiramycin III and II, among which, the content of isovalerylspiramycin III is no less than 30 wt %, the total content of isovalerylspiramycin III, II and I is no less than 60 wt %, and the content of acylspiramycin is 80-98 wt %. Specific optical rotation of said levocarrimycin is [?]D=?52°˜?57° in the solution of 0.02 g/ml chloroform at temperature of 25° C. The present invention also relates to the crystalline compound of isovalerylspiramycin III, II or I in levocarrimycin, and pharmaceutical compositions containing the said levocarrimycin.Type: ApplicationFiled: May 25, 2011Publication date: June 13, 2013Applicant: Shenyang Toglian Group Co., Ltd.Inventors: Yang Jiang, Yuyou Hao
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Patent number: 8461121Abstract: Described are methods for making macrolides, and, in particular, a method for making optionally substituted 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide and derivatives thereof, as well as uses of macrolides to make medicaments, methods of treatment using macrolides, and methods for making intermediates that, inter alia, may be used to make macrolides. Also described are solvated and non-solvated crystalline forms of 20,23-dipiperidinyl-5-O-mycaminosyl-tylonolide, as well as methods for making such crystalline forms, medicaments comprising (or derived from) such crystalline forms, methods for making medicaments comprising (or derived from) such crystalline forms, methods of treatment using such crystalline forms, and kits comprising such crystalline forms.Type: GrantFiled: February 22, 2012Date of Patent: June 11, 2013Assignee: Intervet International B.V.Inventors: Ralf Warrass, Fritz Blatter, Timo Rager
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Publication number: 20130143829Abstract: The present invention provides pyrethroid/macrocyclic lactone-containing topical formulations that are effective against animal pests, including ecto- and endoparasites. The formulations may be used for combating parasites in or on birds and mammals. The invention also provides for an improved method for eradicating, controlling and preventing parasite and/or pest infestation of birds and mammals.Type: ApplicationFiled: December 6, 2011Publication date: June 6, 2013Inventor: Robert Holmes
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Patent number: 8455452Abstract: The present invention relates to a bioadhesive endoparasiticidal gel composition comprising doramectin, having a high degree of adhesion to equine oral mucosa and having a sweet flavor greatly facilitating the dosing thereof, methods for the preparation thereof and methods for treating a condition comprising administering said composition.Type: GrantFiled: August 28, 2009Date of Patent: June 4, 2013Assignee: Agrovet Market, S.A.Inventors: Edgar Régulo Vega Carrasco, José Fernando Tang Ploog, Jorge Fabián Ruiz Herrera, Umberto Calderon Ojeda
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Publication number: 20130137571Abstract: The present invention relates to a novel crystalline modification of fipronil, to a process for the preparation of the same, to pesticidal and parasiticidal mixtures and compositions comprising said crystalline modification and to their use for combating pests and parasites.Type: ApplicationFiled: January 22, 2013Publication date: May 30, 2013Applicant: BASF SEInventors: Heidi Emilia SAXELL, Peter ERK, Claude TARANTA, Thomas KROEHL, Gerhard COX, Martin SUKOPP, Stefan SCHERER, Antti OJALA, Gautam R. DESIRAJU, Rahul BANERJEE, Prashant M. BHATT
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Publication number: 20130125267Abstract: The present invention, comprising: [(3S,4R,4aR,6S,6aS,12R,12a5,12b5)-3-(cyclopropanecarbonyloxy)-6,12-dihy-droxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,2,3,4,4a,5,6,6a,12a,12b-decahydro-11H,12H-benzo[f]pyrano[4,3-b]chromen-4-yl]methyl cydopropanecarboxylate (compound II) and a pesticidal compound II; in synergistic effective amounts.Type: ApplicationFiled: May 27, 2011Publication date: May 16, 2013Applicant: BASF SEInventors: Matthias Pohlman, Markus Gewehr, Tatjana Sikuljak, Juergen Langewald
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Patent number: 8440633Abstract: A composition comprising 2-desoxoparaherquamide and abamectin for the treatment of a parasitic infestation in mammals.Type: GrantFiled: June 16, 2008Date of Patent: May 14, 2013Assignee: AH USA 42 LLCInventors: Timothy G. Geary, Peter Rolfe
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Publication number: 20130108563Abstract: Pharmaceutical/dermatological emulsions containing at least one avermectin compound, notably ivermectin, include at least one fatty phase and at least one aqueous phase, the at least one avermectin compound being solubilized in the fatty phase, which emulsions are useful for the treatment of a variety of dermatological conditions/afflictions, in particular rosacea.Type: ApplicationFiled: December 19, 2012Publication date: May 2, 2013Applicant: Galderma S.A.Inventor: Galderma S.A.
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Publication number: 20130109642Abstract: Administration of at least one compound of the family of the avermectins or of the family of the milbemycins, notably ivermectin, is useful for the treatment of ophthalmic pathologies, including ocular rosacea.Type: ApplicationFiled: December 17, 2012Publication date: May 2, 2013Applicant: Galderma S.A.Inventor: Galderma S.A.
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Publication number: 20130102552Abstract: A composition comprising a carboxamide compound represented by following formula (I), wherein R1 represents a hydrogen atom or a methyl group, and R2 represents a methyl group, a difluoromethyl group or a trifluoromethyl group, and abamectin is provided by the present invention, and this composition has an excellent pesticidal effect.Type: ApplicationFiled: April 25, 2011Publication date: April 25, 2013Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventor: Yuichi Matsuzaki
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Patent number: 8425925Abstract: Pesticidal compositions and articles providing topical application of a mixture of (1) a macrolide of the avermectin/milbemycin class, such as, but not limited to ivermectin, abamectin, or milbemectin, and (2) a synergist of the aryl aliphatic ether-class, such as, but not limited to piperonyl butoxide, present in (3) a weight ratio of synergist:macrolide that is great than 1:1. The compositions and articles demonstrate efficacy, even in point-of-contact applications, against various pests of domestic animals, such as, but not limited to arthropod ectoparasites including horn flies and buffalo flies. Methods are provided in which compositions can be employed as pour-ons, spot-ons, dusts, or sprays for direct topical application to the domestic animal; or in which articles comprising a polymer resin base, such as an ear tag, from which the active ingredients of the composition can be released, are affixed to the animal to provide long-term delivery.Type: GrantFiled: March 5, 2008Date of Patent: April 23, 2013Assignee: Y-Tex CorporationInventor: Joe D. Kellerby
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Publication number: 20130096077Abstract: A method for the synergistic plant nematode control in sugar cane with a mixture of fipronil and abamectin comprising fipronil and abamectin in a ratio by weight of from 1:10 to 10:1, wherein the mixture is applied to sugar cane in furrow, a method for the synergistic plant nematode control in sugar cane with a mixture of fipronil and abamectin comprising fipronil and abamectin in a ratio by weight of from 1:10 to 10:1, wherein the mixture is applied to plant propagation materials of sugar cane, and a method which combines synergistic plant nematode control with (preferably synergistic) improvement of the plant health of sugar cane plants.Type: ApplicationFiled: June 21, 2011Publication date: April 18, 2013Applicant: BASF SEInventors: Alexander Guttenkunst Prade, Antonio Cesar Azenha
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Publication number: 20130095051Abstract: Pharmaceutical/dermatological compositions containing at least one avermectin compound, e.g., ivermectin and metronidazole or salt, ester or derivative thereof, are useful for treating afflictions of the skin, especially rosacea.Type: ApplicationFiled: December 6, 2012Publication date: April 18, 2013Applicant: GALDERMA S.A.Inventor: Galderma S.A.
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Publication number: 20130090296Abstract: The present invention relates to formulations for controlling parasites, comprising a combination of macrocyclic lactone compound and levamisole wherein the levamisole is in particulate form suspended in a non-aqueous solventType: ApplicationFiled: June 23, 2011Publication date: April 11, 2013Inventors: Hyun Sun Cho, Perterson Fabiano Lopes
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Publication number: 20130090295Abstract: A method of promoting or improving the feed efficiency and the muscle to fat ratio in animals by administering to the animals a therapeutically effective amount of a pure or substantially pure RR-isomer of ractopamine is disclosed. Also disclosed are animal feed preparations and compositions and pharmaceutical preparations capable of increasing lean meat deposition in an animal or decreasing body fat, or promoting or improving the growth of an animal or improving the feed efficiency of an animal. Feed preparation, compositions and pharmaceutical preparations including therapeutically effective amounts of a pure or substantially pure RR-isomer of ractopamine are disclosed.Type: ApplicationFiled: November 29, 2012Publication date: April 11, 2013Applicant: BRIDGE PHARMA, INC.Inventor: BRIDGE PHARMA, INC.
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Patent number: 8415311Abstract: Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin.Type: GrantFiled: December 2, 2011Date of Patent: April 9, 2013Assignee: Galderma S.A.Inventors: Vincent Manetta, Gary R. Watkins
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Patent number: 8415310Abstract: This invention recites isoxazoline substituted azetidine derivatives of Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, and their use as a parasiticide in mammals and birds. R1a, R1b, R1c, R2, R3, R4, R6, and n are as described herein.Type: GrantFiled: August 4, 2011Date of Patent: April 9, 2013Assignee: AH USA 42 LLCInventors: Valerie A. Vaillancourt, Nathan Anthony Logan Chubb, Michael Curtis, William Howson, Graham M. Kyne, Sanjay Menon, Susan M. K. Sheehan, Donald J. Skalitzky, John A. Wendt
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Publication number: 20130085064Abstract: The present invention relates to pesticidal mixtures comprising a component A and a component B, wherein component A is a compound of formula (I) wherein A1, A2, R1, R2, R3, R4 and R5 are as defined in claim 1 and one of Y1 and Y2 is S, SO or SO2 and the other is CH2 and component B is an insecticide or nematicidal biological agent as defined in claim 1. The present invention also relates to methods of using said mixtures for the control of pests.Type: ApplicationFiled: February 3, 2011Publication date: April 4, 2013Applicant: SYNGENTA CROP PROTECTION LLCInventors: Patrik Hoegger, Ana Cristina Dutton, Max Angst, Jérôme Yves Cassayre
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Patent number: 8404649Abstract: This invention recites naphthyl isoxazoline oxime derivatives of Formula (1) geometric isomers, stereoisomers thereof, pharmaceutically or veterinarily acceptable salts thereof, compositions thereof, and their use as a parasiticide in animals. The variables, R1a, R1b, R1c, R2, R3, and are as described herein.Type: GrantFiled: September 15, 2011Date of Patent: March 26, 2013Assignee: AH USA 42 LLCInventors: Michael Curtis, Edmund L. Ellsworth
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Publication number: 20130065846Abstract: This invention relates to topical compositions for combating ectoparasites and endoparasites in animals, comprising at least one isoxazoline active agent and a pharmaceutically acceptable carrier, optionally in combination with one or more additional active agents. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.Type: ApplicationFiled: September 12, 2012Publication date: March 14, 2013Inventors: Mark D. Soll, Joseph K. Rosentel, JR., James Pate, Natalya Shub, Monica Motwani-Tejwani, Carol Belansky
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Publication number: 20130065848Abstract: Disclosed are levoisovalerylspiramycin I, II or III, preparations, preparing methods and uses thereof. The preparations comprise levoisovalerylspiramycin I, II or III and pharmaceutically acceptable carrier and/or adjuvant, wherein the purity of levoisovalerylspiramycin I, II or III is above 90 wt %. The levoisovalerylspiramycin I, II or III has a good antibacterial activity, and the preparations include solution for injection, powder for injection or lyophilized powder for injection.Type: ApplicationFiled: May 25, 2011Publication date: March 14, 2013Applicant: Shenyang Tonglian Group Co., Ltd.Inventors: Yang Jiang, Yuyou Hao
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Publication number: 20130065847Abstract: The invention relates to a synergistic composition for controlling endoparasites in and on animals, which comprises a combination of (A) a compound of formula (I) and (B) abamectin. (C) The compositions are useful in the control of endoparasites, in particular helminths, in and on warm-blooded animals.Type: ApplicationFiled: March 24, 2011Publication date: March 14, 2013Inventors: Peter Francis Rolfe, Sarah Miller, Miriam Reiser, Susanne Christine Wieland-Berghausen
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Publication number: 20130064780Abstract: Pharmaceutical/dermatological compositions useful for the prevention/treatment of disorders of the skin, especially rosacea, contain thus effective amounts of at least one avermectin compound, e.g., ivermectin, and at least one azelaic acid compound or salt or derivative thereof, formulated into a physiologically acceptable medium therefor.Type: ApplicationFiled: March 1, 2012Publication date: March 14, 2013Applicant: Galderma S.A.Inventors: Alexandre KAOUKHOV, Colette PERNIN
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Publication number: 20130059730Abstract: A method of controlling or preventing damage to a plant, which comprises applying to the plant, part of a plant, plant organ, and/or plant propagation material thereof, or surrounding area thereof a combination comprising (I) abamectin, and (II) etoxazole, in any desired sequence or simultaneously.Type: ApplicationFiled: January 24, 2011Publication date: March 7, 2013Applicants: Kyoyu Agri Company, Ltd., Syngenta Participations AGInventors: Shinji Sugii, Teruichi Morimoto, Manami Tanji
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Publication number: 20130053336Abstract: The invention relates to a method for treating infections of bacteria of the Chlamydiaceae family using a ?-lactam. The invention also relates to a method for treating diseases caused by an infection of bacteria of the Chlamydiaceae family using a ?-lactam.Type: ApplicationFiled: January 13, 2011Publication date: February 28, 2013Inventors: Philippe Verbeke, Maud Dumoux, Colette Kanellopoulos
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Publication number: 20130035284Abstract: The present invention concerns methods and compositions involving small molecule inhibitors for the treatment or prophylaxis of flavivirus infection, such as dengue virus and West Nile virus.Type: ApplicationFiled: March 5, 2012Publication date: February 7, 2013Applicant: The Board of Regents of the University of Texas SystemInventors: Stanley J. Watowich, Suzanne M. Tomlinson, Scott Gilbertson
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Publication number: 20130035303Abstract: The invention relates to a new rapid release oral formulation of fipronil or imidacloprid for the effective control of blood-sucking insect populations. Embodiments of the invention relate to their use by incorporation into a feed-through formulation that can be administered orally to host animals such as birds, goats, dogs, and cattle for the rapid effective control of blood sucking insects. The formulation is fast acting and the residue of the chemicals present in the feces serves as a larvacide, effectively controlling newly hatched larvae.Type: ApplicationFiled: April 21, 2011Publication date: February 7, 2013Applicant: Genesis Laboratories, Inc.Inventor: Richard Poche
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Publication number: 20130034612Abstract: Compositions and nanoemulsions containing lipid nanocapsules dispersed in a hydrophilic phase, such nanocapsules including at least one avermectin compound, are useful for the treatment of dermatological pathologies, e.g., rosacea.Type: ApplicationFiled: October 9, 2012Publication date: February 7, 2013Applicant: GALDERMA S.A.Inventor: Galderma S.A.
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Patent number: 8361974Abstract: Administration of at least one compound of the family of the avermectins or of the family of the milbemycins, notably ivermectin, is useful for the treatment of ophthalmic pathologies, including ocular rosacea.Type: GrantFiled: June 14, 2011Date of Patent: January 29, 2013Assignee: Galderma S.A.Inventors: Alexandre Kaoukhov, Christophe Villard, Philippe Bouissou
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Publication number: 20130023490Abstract: The present invention provides for, inter alia, novel topical formulations comprising at least one 1-N-arypyrazole derivative and amitraz and to methods for treating, controlling, or preventing parasite infestations on mammals or birds The inventive formulations include spot-on, pour-on or spray formulations and may include a further ectoparasiticide, such as an IGR compound, an avermectin or milbemycin derivative, or a pyrethroid insecticides, and anthelmintics, such as benzimidazoles and imidazothiazoles. The inventive formulation provides a larger duration of parasite control at a faster rate of control. The inventive formula remains effective up to three months from the first application. Moreover, the inventive formulations prevent tick attachment to the animal, thereby providing protection against tick borne diseases. The ectoparasites which may be controlled, treated or prevented by the present invention includes ticks, fleas, mites, mange, lice, mosquitoes, flies and cattle grubs.Type: ApplicationFiled: July 23, 2012Publication date: January 24, 2013Inventors: Albert BOECKH, Luiz Gustavo CRAMER, Mark D. SOLL
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Patent number: 8357717Abstract: Substituted spiroamide compounds corresponding to formula (I): wherein A, B, Q1, Q2, Q3, Q4, R1, R8, R9a, R9b, R12, R13, R200 and R210 have defined meanings, processes for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds for treating or inhibiting pain or other conditions mediated at least in part by the bradykinin 1 receptor (B1R).Type: GrantFiled: February 5, 2010Date of Patent: January 22, 2013Assignee: Gruenenthal GmbHInventors: Stefan Schunk, Melanie Reich, Michael Engels, Tieno Germann, Ruth Jostock, Sabine Hees
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Publication number: 20120316124Abstract: The present invention relates to compounds formula (I), wherein P is P1, P2, heterocyclyl or heterocyclyl substituted by one to five Z; and wherein A1, A2, A3, A4, G1, R1, R2, R3, R4, R5, R6, R17, R18, R19 and R20 are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present invention relates to processes and intermediates for preparing compounds of formula (I), to insecticidal, acaricidal, nematicidal and molluscicidal compositions comprising the compounds of formula (I) and to methods of using the compounds of formula (I) to control insect, acarine, nematode and mollusc pests.Type: ApplicationFiled: February 17, 2011Publication date: December 13, 2012Applicant: SYNGENTA CROP PROTECTION LLCInventors: Thomas Pitterna, Myriem El Qacemi, Jerome Yves Cassayre, Peter Renold, Vladimir Bobosik