Three Substituent Nitrogens Bonded Directly To The Three Carbons Of The Triazine Ring Patents (Class 544/196)
  • Patent number: 10336914
    Abstract: Methods and compositions related to chemically active hexahydrotriazine inorganic-organic hybrid coatings are described. The coatings have affinity for sulfur compounds, and thus may bind or capture sulfur containing contaminants and gases. The coatings have organosilicon containing functional groups and segments, and may also contain silica particles, which cumulatively enhances adhesion, abrasion resistance and further provides steric barriers to gaseous diffusion. The coatings have utility as protective barrier coatings in the field of electronics.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: July 2, 2019
    Assignee: International Business Machines Corporation
    Inventors: Dylan J. Boday, Jeannette M. Garcia, James L. Hedrick, Jason T. Wertz, Rudy J. Wojtecki
  • Patent number: 10172864
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer comprising administering to a subject in need thereof a compound described herein.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: January 8, 2019
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Zenon D. Konteatis, Janeta Popovici-Muller, Jeremy M. Travins, Robert Zahler, Zhenwei Cai, Ding Zhou
  • Patent number: 10071972
    Abstract: This invention relates to a process for the preparation of triazine carbamates by reacting a mixture of an aminotriazine A having at least two amino groups per molecule, an organic carbonate C, and a base B selected from the group consisting of alkoxides, and arylalkoxides of metals M, which may be alkali or earth alkali metals, and a solvent S which is a monohydric alcohol solvent R2OH or a mixture of solvents that comprises a monohydric alcohol R2OH, and a monohydric alcohol R3OH, or a mixture of solvents that comprises a monohydric alcohol R2OH with a further solvent selected from the group consisting of ether, alcohol, and hydrocarbon solvents, and adding to the products of the said reaction, an acid or a solution of an acid in a solvent.
    Type: Grant
    Filed: September 7, 2015
    Date of Patent: September 11, 2018
    Assignee: ALLNEX NETHERLANDS B.V.
    Inventor: Lawrence Flood
  • Patent number: 9969703
    Abstract: The present invention discloses a triazine-containing photocurable resin and a preparation method thereof. The preparation method of the resin comprises the following steps of: (1) Dissolving the hexamethylolmelamine the unsaturated fatty acids and a catalyst in a solvent, keeping a reaction going, separating and extracting the reaction product after the reaction ends, obtaining triazine-containing fatty acid ester; (2) adding 50 wt % hydrogen peroxide, a catalyst and a solvent, namely methylbenzene, into the triazine-containing fatty acid ester prepared in step (1), keeping a reaction going, obtaining triazine-containing fatty acid ester epoxy resin; (3) adding a polymerization inhibitor and a catalyst into acrylic acid, dropping the triazine-containing fatty acid ester epoxy resin prepared in step (2), keeping a reaction going, and obtaining the triazine-containing photocurable resin.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: May 15, 2018
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Ren Liu, Xiaopeng Zhang, Zhiquan Li, Jingcheng Liu, Jing Luo, Xiaoya Liu
  • Patent number: 9926231
    Abstract: The invention relates to dispersants for inorganic particles, preferably for hydraulic binders, which comprises the following structural units: i) at least one triazine structural unit, ii) at least one polyalkylene glycol structural unit, and iii) at least two phosphoric ester structural units on at least one carbon atom of one or more aromatic triazine rings of the formulae (IIa) and/or (IIb): —N—(CH2CH2—O—PO3H2)2,??(IIa) and —NH—CH2CH2—O—PO3H2.??(IIb) The invention also relates to a process for preparing the dispersants, to building material mixtures comprising one or more dispersants and one or more inorganic binders. The invention relates to the use of the dispersants as a water reducing agent, as a means for reducing the viscosity and for enhancing the early strengths of aqueous inorganic binders, and also to the use as a grinding aid in the production of cement.
    Type: Grant
    Filed: December 7, 2012
    Date of Patent: March 27, 2018
    Assignee: Construction Research & Technology, GmbH
    Inventors: Joachim Dengler, Alexander Kraus
  • Patent number: 9737875
    Abstract: Disclosed herein are methods and compositions for purifying proteins from crude solutions.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 22, 2017
    Assignees: Impossible Foods Inc., The Board of Trustees of the Leland Stanford Junior University
    Inventors: Patrick O'Reilly Brown, R. Edward Watts, Pehr Harbury
  • Patent number: 9603852
    Abstract: Disclosed are methods and compositions for treating pulmonary arterial hypertension and/or obesity using inhibitors of prostaglandin transporter (PGT) activity.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: March 28, 2017
    Assignee: Albert Einstein College of Medicine, Inc.
    Inventors: Victor L. Schuster, Yuling Chi
  • Patent number: 9556312
    Abstract: A polyimide precursor, a polyimide using the polyimide precursor, and a polyimide film using the polyimide. The polyimide film has excellent adhesiveness to a metal layer or an adhesive, and has improved heat resistance. The polyimide solution may be used as a coating material.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: January 31, 2017
    Assignees: NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY, UBE INDUSTRIES, LTD.
    Inventors: Yoshiyuki Oishi, Shin-ichiro Kohama, Nobuharu Hisano
  • Patent number: 9511565
    Abstract: A polyimide precursor for obtaining a polyimide film having excellent adhesiveness to metals and improved transmittance in the UV-visible range, a polyimide in which the polyimide precursor is used, a polyimide film in which the polyimide is used, and a method for manufacturing a triazine compound used for manufacturing the polyimide precursor, polyimide film and polyimide.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: December 6, 2016
    Assignees: UBE INDUSTRIES, LTD., NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY
    Inventors: Yoshiyuki Oishi, Nobuharu Hisano, Shin-ichiro Kohama, Taizou Murakami, Hiroaki Yamaguchi
  • Patent number: 9499498
    Abstract: This invention relates to a process for the preparation of triazine carbamates by reacting a mixture of an aminotriazine A having at least two amino groups per molecule, an organic carbonate C which is preferably an acyclic carbonate, and a mixture B of bases comprising at least two basic metal compounds B1 and B2 individually selected from the group consisting of hydrides, amides, alkoxides, and arylalkoxides of metals, wherein the metal in B1 is not the same as the metal in B2.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: November 22, 2016
    Assignee: ALLNEX IP S.À.R.L.
    Inventors: William Jacobs, III, Lawrence A. Flood
  • Patent number: 8987383
    Abstract: The object of the present invention is to provide a novel triazine derivative which is excellent in the heat resistance and rapid in the cross-linking rate, and can be suitably used as a crosslinking agent. The present invention relates to a triazine derivative represented by the general formula (I). (In the formula (I), Y and X are each independently, represents a diallylamino group, mono-allylamino group, allyloxy group or methallyloxy group; and Z represents an allyloxy group or methallyloxy group).
    Type: Grant
    Filed: February 3, 2011
    Date of Patent: March 24, 2015
    Assignee: Nippon Kasei Chemical Company Limited
    Inventors: Mabuko Yamaura, Yukio Orikasa, Kazuya Senzaki, Takashi Kagawa
  • Publication number: 20150073103
    Abstract: Multifunctional melamine epoxy resins, methylols and amines are provided. Methods of making multifunctional melamine epoxy resins, methylols and amines are also provided.
    Type: Application
    Filed: November 19, 2014
    Publication date: March 12, 2015
    Inventor: Georgius Abidal ADAM
  • Patent number: 8952150
    Abstract: Disclosed are compounds for inhibiting prostaglandin transporter (PGT) activity, pharmaceuticals compositions including the compounds, and methods of treating subjects using the compounds.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: February 10, 2015
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Victor L. Schuster, Yuling Chi, Andrew S. Wasmuth, Richard S. Pottorf, Gary L. Olson
  • Publication number: 20140371224
    Abstract: The present invention includes compounds, and compositions comprising the same, that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of the invention.
    Type: Application
    Filed: August 29, 2014
    Publication date: December 18, 2014
    Inventors: JAMES C. MANNION, SCOTT L. DAX, DUNCAN EUAN MACINTYRE, FRANCIS JOHN GOLDER, JAMES FRANCIS MCLEOD
  • Patent number: 8911858
    Abstract: Multifunctional melamine epoxy resins, methylols and amines are provided. Methods of making multifunctional melamine epoxy resins, methylols and amines are also provided.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: December 16, 2014
    Assignee: Empire Technology Development LLC
    Inventor: Georgius Abidal Adam
  • Patent number: 8912323
    Abstract: The present invention relates to dendrimer synthesis. Specifically, the present invention relates to triazine scaffolds capable of click chemistry for one-step synthesis of functionalized dendrimers, and methods of making and using the same.
    Type: Grant
    Filed: September 30, 2010
    Date of Patent: December 16, 2014
    Assignee: The Regents of the University of Michigan
    Inventors: James R. Baker, Jr., Hong Zong, Thommey P. Thomas
  • Patent number: 8912293
    Abstract: A resin composition is provided. The resin composition comprises: an epoxy resin; a hardener, which comprises a melamine compound of Formula I: wherein, R is the same with or different from each other and has the formula of R1 and R2 are individually selected from a group consisting of H, a halogen, a substituted or unsubstituted C1-C15 alkyl group, a substituted or unsubstituted C1-C15 aloxy group, a substituted or unsubstituted C3-C15 cycloalkyl group, a substituted or unsubstituted C6-C20 aryl group, a substituted or unsubstituted C6-C20 aryloxy group, a substituted or unsubstituted C1-C15 unsaturated hydrocarbyl group, a naphthol group, a phenanthrenol group, and a dicyclopentadiene group, with a proviso that R2 is not H; and m is 1 or 2, wherein the amount of the hardener is about 20 parts by weight to about 150 parts by weight per 100 parts by weight of the epoxy resin.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: December 16, 2014
    Assignee: Taiwan Union Technology Corporation
    Inventor: Hsin-Ho Wu
  • Patent number: 8895731
    Abstract: The invention relates to novel intermediates for the preparation of substituted triazines used in particular in the cosmetic, detergent, coating, plastics and textile industries. The invention also relates to the processes for preparation of said intermediates and for the conversion of the latter into final products.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: November 25, 2014
    Assignee: 3V Sigma S.p.A.
    Inventors: Francesco Maestri, Luca Bemporad, Ferruccio Berte′
  • Patent number: 8859679
    Abstract: The instant invention relates to storage stable aqueous solutions of stilbene optical brighteners with polyvinyl alcohols which can be directly used by the papermaker in that they may be diluted with water and/or be metered directly into a coating composition, to provide coated papers of a particularly high whiteness.
    Type: Grant
    Filed: April 5, 2006
    Date of Patent: October 14, 2014
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Andrew Clive Jackson, Alec Stewart Tindal, Mariela Gauto
  • Patent number: 8821688
    Abstract: The instant invention relates to mixed salts of optical brighteners of formula (1), wherein M represents a mixture of Mg2+ with another cation, which provide for superior optical brightening effects when applied to the surface of paper.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: September 2, 2014
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Andrew Clive Jackson, David Puddiphatt, Cédric Klein
  • Publication number: 20140235766
    Abstract: Use of one or more amino-triazine based Mannich-compounds and/or their dimers or trimers and/or one or more precondensate therefrom, including special new amino-triazine based Mannich-compounds, as antioxidant and/or UV-stabilizer for organic material, preferably for polymers; the stabilized material and use of the stabilized material.
    Type: Application
    Filed: September 20, 2012
    Publication date: August 21, 2014
    Inventors: Rene Dicke, Andreas Meinecke, Christian Paulik, Klaus Bretterbauer, Helmut Puchinger, Jingbo Wang, Clemens Schwarzinger
  • Patent number: 8802848
    Abstract: The present invention relates to Melamine based Mannich compounds of the general formulae (1)-(12) and a process for synthesizing melamine based Mannich-products comprising the steps of a) reacting at least one substituted melamine with at least one aldehyde, in particular formaldehyde, under basic conditions to form at least one OH-containing compound, b) reacting the at least one OH-containing compound in the presence of a catalyst to form at least one mannich-base, c1) reacting the at least one mannich-base with at least one enol-forming carbonyl compound, or c2) reacting the at least one mannich-base with at least one aromatic compound, and d) working up the reaction mixture. The invention relates further to precondensates obtainable from these products.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: August 12, 2014
    Assignee: Borealis Agrolinz Melamine GmbH
    Inventors: René Dicke, Christoph Hahn, Martin Burger, Andreas Endesfelder, Katarina Rot, Clemens Schwarzinger, Klaus Bretterbauer, Heinrich Trischler, Harald Schmidt
  • Publication number: 20140212980
    Abstract: The present invention provides a probe that further promotes ionization in proteomic analysis using mass spectrometry, and a high-sensitive mass spectrometry method for a protein using such a probe. Further, the present invention provides an ionization-enhancing probe that can be used even for a protein that has a high degree of hydrophobicity and quickly turns over, and a high-sensitive mass spectrometry method for a protein using such a probe. A thiol probe for a protein, which is represented by the following formula (I): [Chemical Formula 1] wherein R1 represents a linker group, and R2 represents a substituted ammonium group or a substituted amino group. A mass spectrometry method for a protein, comprising the steps of: obtaining a modified protein by reacting the thiol probe with a protein to be subjected to mass spectrometry; and subjecting the modified protein to mass spectrometry.
    Type: Application
    Filed: August 17, 2012
    Publication date: July 31, 2014
    Inventors: Takashi Shimada, Taka-Aki Sato, Koichi Tanaka
  • Publication number: 20140179838
    Abstract: Multifunctional melamine epoxy resins, methylols and amines are provided. Methods of making multifunctional melamine epoxy resins, methylols and amines are also provided.
    Type: Application
    Filed: October 31, 2012
    Publication date: June 26, 2014
    Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLC
    Inventor: Georgius Abidal Adam
  • Patent number: 8759584
    Abstract: Compounds of formula (I) or salts thereof, in which R1, R2, R3, R4, R5, R6, X and Y are defined as in claim 1, can be prepared by a process characterized in that a compound of the formula (II) or a salt thereof, is reacted to a compound of the formula (III) or a salt thereof, and an aluminium(III) source, optionally, in the presence of a protic additive or solvent selected from the group consisting of alcohols or amines. The compounds (I) are suitable to be used for the preparation of heterocyclic compounds corresponding to (I) where the group Al(X)(Y) is replaced with an optionally substituted carbon atom, or s-triazine derivatives thereof.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: June 24, 2014
    Assignee: Bayer Cropscience AG
    Inventor: Mark James Ford
  • Patent number: 8747999
    Abstract: The present invention related to (micro-or nano-) capsules that have two different functional groups on the outer shell of the particles that allow deposition onto the textile surfaces (i.e. exhibit substantivity) and subsequent covalent bonding of the particles onto the textile (i.e. are reactive towards the fiber).
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: June 10, 2014
    Assignee: BASF SE
    Inventors: Bryan David Grey, Kishor Kumar Mistry, Chun-tian Zhao
  • Patent number: 8742003
    Abstract: The present invention relates to silylated amino resins, to processes for preparing them, to their use, and to coating compositions comprising them.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: June 3, 2014
    Assignee: BASF SE
    Inventors: Christina Haaf, Markus Hickl, Ruediger Stark, Horst Hintze-Bruening, Bernd Bruchmann, Dirk Schmelter, Thomas Gloege, Christine Roesch
  • Patent number: 8722674
    Abstract: Disclosed herein are a 1,3,5-triazine-2,4,6-triamine compound or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a composition for preventing or treating metabolic syndromes, diabetes, or cancers with deletion of P53 gene, which comprises the same.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: May 13, 2014
    Assignee: Hanall Biopharma Co., Ltd.
    Inventors: Hyae Gyeong Cheon, Kwang-Rok Kim, Sang Dal Rhee, Won Hoon Jung, Jong-Cheol Lee, Sung Wuk Kim, Sung Soo Jun
  • Patent number: 8716472
    Abstract: A tri-podal compound according to formula (I) wherein, each Z is the same and is a substituted or unsubstituted N-heteroaromatic single-, multiple-, or fused-ring; and each A is the same, and can represent a direct bond between the cyclohexane ring and Z, or a carboxamide group (—C(O)—N(H)—). Use of the compounds in combinatorial libraries, methods of making the tripodal compounds, sensor devices for detecting carbohydrate targets, and methods of using the tripodal compounds to detect carbohydrate targets in a sample are also disclosed.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: May 6, 2014
    Assignee: University of Rochester
    Inventors: Benjamin L. Miller, Prakash B. Palde, Peter C. Gareiss
  • Publication number: 20140066552
    Abstract: The present invention relates to silylated amino resins, to processes for preparing them, to their use, and to coating compositions comprising them.
    Type: Application
    Filed: November 8, 2013
    Publication date: March 6, 2014
    Applicant: BASF SE
    Inventors: Bastian NOLLER, Reinhold SCHWALM, Christine ROSCH, Thomas BREINER, Jean-Francois STUMBE, Christina HAAF
  • Patent number: 8657947
    Abstract: The present invention relates to silylated amino resins, to processes for preparing them, to their use, and to coating compositions comprising them.
    Type: Grant
    Filed: September 10, 2012
    Date of Patent: February 25, 2014
    Assignee: BASF SE
    Inventors: Bastian Noller, Reinhold Schwalm, Christine Roesch, Thomas Breiner, Jean-Francois Stumbe, Christina Haaf
  • Publication number: 20140011715
    Abstract: Melamine derivatives and mixtures thereof with aqueous systems, a process for inhibiting corrosion of metals and metal alloys with melamine derivatives and mixtures thereof and the use of melamine derivatives and mixtures thereof as corrosion inhibitors for aqueous systems, for example water/oil mixtures, especially in the field of cleaning compositions, cooling fluids, oilfield chemicals or lubricants.
    Type: Application
    Filed: July 2, 2013
    Publication date: January 9, 2014
    Applicant: BASF SE
    Inventors: Roland BOEHN, Benjamin SCHAEFER, Christian BITTNER, Fabien Jean BRAND, Peter HAENGGI
  • Patent number: 8501939
    Abstract: Compounds of the general formula (I): in which inter alia Q1 represents —NR1R3, —OR1 or —SR1 and Q2 represents —NR2R4, —OR2 or —SR2, and A represents the point of attachment to a support matrix, are useful as protein binding ligands when (a) at least one of R1, R2, R3 and R4 includes an alkyl group —CnH2n+1 in which n is greater than or equal to 7; (b) at least two of R1, R2, R3 and R4 independently include an alkyl group —CnH2n+1 or a cycloalkyl group —CnH2n?1 in which n is greater than or equal to 4; or (c) at least three of R1, R2, R3 and R4 independently include a C1-12 alkyl group substituted by —NR5R6 or aryl.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: August 6, 2013
    Assignee: Prometic Biosciences Limited
    Inventors: Jason Richard Betley, James Christopher Pearson, Helen Rosemary Tatton, Ben Martin Beacom
  • Patent number: 8471007
    Abstract: Process for preparing higher 1,3,5-triazine carbamates and 1,3,5-triazine ureas from lower 1,3,5-triazine carbamates.
    Type: Grant
    Filed: April 8, 2005
    Date of Patent: June 25, 2013
    Assignee: BASF SE
    Inventors: Yvonne Heischkel, Eva Wagner, Joerg Schneider, Reinhold Schwalm, Guenter Scherr, Karl Haeberle
  • Publication number: 20130048564
    Abstract: A method of treating an aqueous liquid. The method comprises providing an aqueous feed liquid comprising water and at least one solute to a first side of a membrane. A draw solution comprising water and a draw solute comprising at least one of a phosphazene compound and a triazine compound is provided to a second side of the membrane. At least a portion of the water of the aqueous feed liquid is osmosed across the membrane and into the draw solution to form a diluted draw solution comprising water and the draw solute. The water of the diluted draw solution is separated from the draw solute of the diluted draw solution to form a purified water product. Draw solutes comprising phosphazene compounds and draw solutes comprising triazine compounds are also disclosed, as are methods of forming the draw solutes.
    Type: Application
    Filed: May 24, 2012
    Publication date: February 28, 2013
    Applicant: BATTELLE ENERGY ALLIANCE, LLC
    Inventors: Frederick F. Stewart, Michael T. Benson, Mark L. Stone
  • Publication number: 20130053520
    Abstract: The object of the present invention to provide a cross-linking agent for a cross-linkable elastomer which is excellent in the heat resistance and rapid in the cross-linking rate in comparison with triallyl isocyanurate (TAIC). The present invention relates to a cross-linking agent for a cross-linkable elastomer comprising a triazine derivative represented by the general formula (I) or prepolymer thereof. (In the formula (I), at least two of X, Y and Z are each independently a diallylamino group, a mono-allyl amino group or allyl-methylamino group, and the rest is a hydrogen atom or a hydrocarbon group which may be substituted.
    Type: Application
    Filed: February 3, 2011
    Publication date: February 28, 2013
    Inventors: Mabuko Yamaura, Yukio Orikasa, Kazuya Senzaki, Takashi Kagawa
  • Patent number: 8361301
    Abstract: The present invention relates to an electrodepositable coating composition comprising a crater control additive.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: January 29, 2013
    Assignee: PPG Industries Ohio, Inc.
    Inventors: Ellor James Van Buskirk, Alan J. Kaylo, Michael G. Sandala, Debra L. Singer, Benjamin Kabagambe, Joseph R. Swanger
  • Publication number: 20130000516
    Abstract: The present invention relates to silylated amino resins, to processes for preparing them, to their use, and to coating compositions comprising them.
    Type: Application
    Filed: September 10, 2012
    Publication date: January 3, 2013
    Applicant: BASF SE
    Inventors: Bastian Noller, Reinhold Schwalm, Christine Rösch, Thomas Breiner, Jean-Francois Stumbe, Cristina Haaf
  • Patent number: 8324379
    Abstract: The present invention provides hydrophobic prodrugs of bases, nucleosides, and nucleotides as well as methods of using the prodrugs as antiviral and anti-cancer chemotherapeutic agents.
    Type: Grant
    Filed: May 16, 2011
    Date of Patent: December 4, 2012
    Assignee: Koronis Pharmaceuticals, Inc.
    Inventors: Richard Daifuku, Alexander Gall, Dmitri Sergueev, Dina Sologub, Kevin Harris
  • Publication number: 20120295911
    Abstract: The present invention includes compositions that are useful in the treatment of breathing control diseases or disorders in a subject in need thereof. The present invention also includes a method of treating a respiratory disease or disorder in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention. The present invention further includes a method of preventing destabilization or stabilizing breathing rhythm in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a pharmaceutical formulation of the invention.
    Type: Application
    Filed: May 29, 2012
    Publication date: November 22, 2012
    Inventors: James C. Mannion, Scott L. Dax, Duncan Euan MacIntyre, Francis John Golder, James Francis McLeod
  • Patent number: 8299244
    Abstract: A melamine derivative of Formula I and its preparing method are provided: wherein, R is the same with or different from each other and has the formula of R1 and R2 are independently selected from a group consisting of H, a halogen, a substituted or unsubstituted C1-C15 alkyl, a substituted or unsubstituted C1-C15 alkoxy, a substituted or unsubstituted C3-C15 cycloalkyl, a substituted or unsubstituted C6-C20 aryl, a substituted or unsubstituted C6-C20 aryloxy, a substituted or unsubstituted C1-C15 unsaturated hydrocarbyl, a naphthol group, a phenanthrenol group, and a dicyclopentadiene group, with a proviso that R2 is not H; and m is 1 or 2.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: October 30, 2012
    Assignee: Taiwan Union Technology Corporation
    Inventor: Hsin-Ho Wu
  • Patent number: 8278443
    Abstract: The present invention relates to a resin composition for an optical film, comprising a polyarylate resin and an amino resin having a triazine structure, and to an optical film prepared by using the same. By using the resin composition for an optical film, a thickness direction retardation can be controlled, while having a negative value, during a step of fabricating the optical film, an in-plane retardation can be controlled, and the optical film can be used as a substrate of a display instead of a glass substrate without an additional retardation compensation film.
    Type: Grant
    Filed: January 4, 2008
    Date of Patent: October 2, 2012
    Assignee: LG Chem, Ltd.
    Inventors: Sang-Uk Ryu, Dong-Ryul Kim, Dae-Woo Nam
  • Patent number: 8263766
    Abstract: A melamine skeleton-bearing organosilicon compound has a film forming ability, water solubility and compatibility with resins. It is prepared by reacting cyanuric chloride with a primary and/or secondary amine compound and neutralizing with a base.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: September 11, 2012
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventor: Kazuhiro Tsuchida
  • Patent number: 8227466
    Abstract: Provided are methods of inhibiting prostaglandin transporter (PGT) activity in mammals. Also provided are methods of determining whether a test compound is an inhibitor of a prostaglandin transporter. Additionally provided are compounds that inhibit prostaglandin transporter activity, and pharmaceutical compositions of those compounds. Methods of inhibiting COX-2 in a mammal are also provided. Additionally, methods of treating pain or inflammation in a mammal are provided.
    Type: Grant
    Filed: May 15, 2007
    Date of Patent: July 24, 2012
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Victor L. Schuster, Yuling Chi, Young-Tae Chang, Jaeki Min
  • Patent number: 8211550
    Abstract: A process for the production of leather using one or more reaction products of (a) triamines or higher amines with (b) at least one compound of the general formula I A1-R1??I where R1 is selected from hydrocarbon radicals having 10 to 5000 carbon atoms, straight-chain or branched, saturated or having from one to three C—C double bonds, and A1 from groups capable of reacting with amines.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: July 3, 2012
    Assignee: BASF SE
    Inventors: Stephan Hüffer, Sebastien Garnier, Oliver Reese, Günter Scherr, Harald Kiesow
  • Patent number: 8198387
    Abstract: Provided is a proton-conducting compound which provides proton conductivity without humidification and is suitable for electrochemical device materials such as solid electrolytes for fuel cells and electrolytes for batteries. Provided also is a proton-conducting polymer. The proton-conducting compound is composed of a melamine compound salt obtained from a melamine compound represented by the following formula (1) and a Bronsted acid and the proton-conducting polymer is obtained by homopolymerizing or copolymerizing the melamine compound salt. In formula (1), R1, R2, R3, R4, and R5 each is independently an alkyl group, an aryl group, an alkenyl group, a heterocyclic group, or a hydrogen atom; at least one of them is a group other than hydrogen; R2 and R3 or R4 and R5 may join together to form a heterocyclic structure; and the alkyl group, the aryl group, the alkenyl group, or the heterocyclic group may have a substituent.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: June 12, 2012
    Assignee: Nippon Steel Chemical Co., Ltd.
    Inventors: Atsushi Kawada, Aya Tashiro
  • Patent number: 8163748
    Abstract: Novel s-triazine compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, where microbial infection is either a direct cause or a related condition.
    Type: Grant
    Filed: May 23, 2008
    Date of Patent: April 24, 2012
    Assignee: New York University
    Inventors: Neville Robert Kallenbach, Young-Tae Chang, Zhigang Liu, Chunhui Zhou, Jaeki Min
  • Patent number: 8153788
    Abstract: Compounds of the formula (I) or salts thereof, in which in which R1 is an optionally substituted amino group or analogous group, and R2 to R7 are each as described herein, are suitable as herbicides and crop growth regulators. The compounds (I) can be prepared by the processes described, via intermediates including novel intermediates for example of the formula (III).
    Type: Grant
    Filed: December 14, 2007
    Date of Patent: April 10, 2012
    Inventors: Hartmut Ahrens, Hansjörg Dietrich, Thomas Auler, Martin Hills, Heinz Kehne, Dieter Feucht, Stefan Herrmann, Kristian Kather, Stefan Lehr
  • Patent number: 8138338
    Abstract: The present invention provides, at least in part, compounds of formula (I): or a pharmaceutically acceptable salt thereof, wherein Z1, Z2, Z3, R1, x, y, R2, R3, R4a, R4b, R5, R6 and R7 are described herein, as well as methods for their identification, their preparation, pharmaceutical compositions containing them, and their use as Aurora A kinase inhibitors in treatment, e.g., of cancer and other proliferative disorders.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: March 20, 2012
    Assignee: GlaxoSmithKline LLC
    Inventor: Matthew Clark
  • Publication number: 20120063976
    Abstract: Methods of removing carbon dioxide comprising contacting a gas mixture comprising carbon dioxide with a sorbent. The sorbent comprises the following chemical structure: wherein at least one of R1, R2, and R3 comprises a primary amine group and wherein the sorbent is not melamine and does not comprise the following chemical structure: Sorbents for removing carbon dioxide are also disclosed.
    Type: Application
    Filed: September 9, 2010
    Publication date: March 15, 2012
    Applicant: BATTELLE ENERGY ALLIANCE, LLC
    Inventor: Michael T. Benson