Heavy Metal Or Aluminum Containing Patents (Class 548/101)
  • Patent number: 5482955
    Abstract: New cyclopropyl-ethyl-azoles of the formula ##STR1## in which R represents alkyl, alkenyl, alkinyl, cycloalkyl which is optionally substituted by alkyl, or optionally substituted aryl, optionally substituted aralkyl or optionally substituted aralkenyl, andZ represents a nitrogen atom or a CH group,and addition products thereof with acids or metal salts are very effective for combating fungi.Novel oxiranes of the formula ##STR2## in which R and Z have the abovementioned meanings,are valuable intermediates.
    Type: Grant
    Filed: April 4, 1995
    Date of Patent: January 9, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Manfred Jautelat, Stefan Dutzmann, Klaus Stenzel, Heinz-Wilhelm Dehne
  • Patent number: 5462955
    Abstract: New azolylmethyl-fluorocyclopropyl derivatives of the formula ##STR1## in which R represents ##STR2## and addition products thereof which acids or metal salts are very effective for combating fungi.New oxiranes of the formula ##STR3## in which R has the abovementioned meaning, are valuable intermediates for the preparation of compounds of the formula (I).
    Type: Grant
    Filed: February 15, 1994
    Date of Patent: October 31, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jurgen Scherkenbeck, Thomas Himmler, Stefan Bohm, Hermann Hagemann, Klaus Stroech, Stefan Dutzmann, Heinz-Wilhelm Dehne, Gerd Hanssler
  • Patent number: 5460669
    Abstract: The energetic salts of 3-nitramino-4-nitrofurazan have a desirable combination of desirable properties such as sufficiently high densities, and low or no hydrogen content. The salts are useful as ingredients in various propellant, explosive, gassifier, and pyrotechnic compositions. 3-Nitramino-4-nitrofurazan is itself a useful energetic compound and is also useful in the synthesis of still further energetic compounds.
    Type: Grant
    Filed: June 28, 1993
    Date of Patent: October 24, 1995
    Assignee: Thiokol Corporation
    Inventors: Rodney L. Willer, Robert S. Day, Dennis J. Park, deceased
  • Patent number: 5409915
    Abstract: Novel bis(platinum) (IV) complexes coupled via diamine bridging agents are taught as well as methods for their preparation. These complexes are to be used as pharmaceutical agents, e.g., for the treatment of cancer and parasitic diseases.
    Type: Grant
    Filed: September 14, 1993
    Date of Patent: April 25, 1995
    Assignee: The University of Vermont and State Agricultural College
    Inventors: Nicholas Farrell, Silvano Spinelli, Mariella Valsecchi, Ernesto Menta
  • Patent number: 5397768
    Abstract: Compounds of the formula ##STR1## are fungicides and herbicides when Z is alkyl, cycloalkyl, aryl, or aralkyl; Q is a triazolyl; X is an aryl group or a heterocyclic group; and W is a variety of functional groups.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: March 14, 1995
    Assignee: Rohm and Haas Company
    Inventors: Steven H. Shaber, Luong T. Nguyen
  • Patent number: 5371065
    Abstract: Fungicidal and plant growth-regulating substituted azolylmethyloxiranes of the formula ##STR1## in which R.sup.1 stands for alkyl,R.sup.2 stands for alkyl,X stands for a nitrogen atom or the CH group,Y stands (or halogen, alkyl, cycloalkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy, halogenoalkylthio, optionally substituted phenyl, optionally substituted phenoxy, optionally substituted phenylalkyl and/or optionally substituted phenylalkoxy andm stands for the numbers 0, 1, 2 or 3,and addition products thereof with acids and metal salts.
    Type: Grant
    Filed: February 2, 1989
    Date of Patent: December 6, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Ludwig Elbe, Karl H. Buchel, Wilhelm Brandes, Stefan Dutzmann, Klaus Lurssen
  • Patent number: 5364870
    Abstract: This invention relates to novel (2-aryl-2-substituted)ethyl-1,2,4- triazoles and the enantiomorphs, acid addition salts and metal salt complexes thereof, as well as their method of preparation and their use as highly active broad-spectrum systemic fungicides.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: November 15, 1994
    Assignee: Rohm and Haas Company
    Inventors: Steven H. Shaber, Katherine E. Flynn
  • Patent number: 5346927
    Abstract: Blowing agents of tetrazoles and their derivatives which have a melting point over 200.degree. C. and are used to manufacture the high quality foaming thermoplastic synthetic resin moldings, especially engineering or superengineering plastic moldings and said blowing agents generate no harmful gases and do not cause the deterioration of the thermoplastic synthetic resin moldings.
    Type: Grant
    Filed: September 8, 1992
    Date of Patent: September 13, 1994
    Assignee: Toyo Kasei Kogyo Company, Ltd.
    Inventors: Atsuhiro Onishi, Koichi Matsunami, Masanao Ebara, Hiroaki Tanaka
  • Patent number: 5334608
    Abstract: New azolylmethyl-cyclopropyl derivatives of the formula ##STR1## in which R represents cyano or a group of the formula ##STR2## Z represents halogen, alkyl having 1 to 4 carbon atoms, halogenoalkyl having 1 to 4 carbon atoms and 1 to 5 halogen atoms, alkoxy having 1 to 4 carbon atoms, halogenoalkoxy having 1 to 4 carbon atoms and 1 to 5 halogen atoms, or alkoximininoalkyl having 1 to 4 carbon atoms in the alkoxy group and 1 to 4 carbon atoms in the alkyl group andm represents the numbers 0, 1 or 2, and addition products thereof with acids or metal salts are very effective for combating fungi.New oxiranes of the formula ##STR3## in which Z and m have the abovementioned meanings, are valuable intermediates for the preparation of compounds of the formula (I).
    Type: Grant
    Filed: February 23, 1993
    Date of Patent: August 2, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jurgen Scherkenbeck, Thomas Himmler, Hermann Hagemann, Stefan Dutzmann, Heinz-Wilhelm Dehne, Gerd Hanssler
  • Patent number: 5304568
    Abstract: New ethyl-triazolyl derivatives of the formula ##STR1## in which R represents halogen,X.sup.1 represents fluorine, chlorine or bromine,X.sup.2 represents fluorine, chlorine or bromine,Z represents halogen, alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, ethyl having 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkoxy having 1 or 2 carbon atoms and 1 to 5 halogen atoms, phenyl, phenoxy, nitro or alkoximinoalkyl having 1 to 4 carbon atoms in the alkoxy moiety and 1 to 4 carbon atoms in the alkyl moiety andm represents the numbers 0, 1, 2 or 3,and addition products thereof with acids or metal salts are very effective for combating fungi.Novel ethyl-triazolyl derivatives of the formula ##STR2## in which R, Z and m have the abovementioned meanings,and addition products thereof with acids or metal salts are very effective for combating fungi.
    Type: Grant
    Filed: August 6, 1993
    Date of Patent: April 19, 1994
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jurgen Scherkenbeck, Michael Lindemann, Stefan Dutzmann, Heinz-Wilhelm Dehne
  • Patent number: 5298624
    Abstract: Stable, organometallic complexes of 5,5-diphenyl-2,4 imidazolidenedione (diphenyl hydantoin) are versatile biocides, effective when applied topically or parenterally to animal tissue, and when applied topically to plants. The diphenyl Hydantoin complexes are seen to prevent animal and plant tissue infections, and may be combined with other materials to inhibit infection.
    Type: Grant
    Filed: November 12, 1992
    Date of Patent: March 29, 1994
    Inventor: Sigmund E. Lasker
  • Patent number: 5298623
    Abstract: This invention describes Cu complexes of bis-oxazolines and their use. These compounds have the following formulas: ##STR1##This project is supported in part by N. I. H. grant GM-35879.
    Type: Grant
    Filed: November 8, 1991
    Date of Patent: March 29, 1994
    Assignee: Massachusetts Institute of Technology
    Inventors: Satoru Masamune, Richard E. Lowenthal
  • Patent number: 5294634
    Abstract: The present invention relates to an orally-administrable osteogenesis promoter, which comprises, as an active ingredient, a zinc salt or complex of L-carnosine, has excellent osteogenesis-accelerating action, and is extremely low in toxicity and side effects.
    Type: Grant
    Filed: April 2, 1992
    Date of Patent: March 15, 1994
    Assignees: Zeria Pharmaceutical Co., Ltd., Hamari Chemicals Co., Ltd.
    Inventor: Masayoshi Yamaguchi
  • Patent number: 5272130
    Abstract: A compound having the formula: ##STR1## and stereoisomers thereof, wherein R.sup.1 is --CH.dbd.CH--X or --C.tbd.C--X where X is hydrogen or straight chain alkyl; R.sup.2 is halophenyl, Z is OR.sup.3 where R.sup.3 is H, alkyl, alkenyl or alkynyl; and acid addition salts and metal complexes thereof. These compounds have fungicidal and plant growth regulating properties. Intermediates for these compounds are also disclosed.
    Type: Grant
    Filed: May 10, 1989
    Date of Patent: December 21, 1993
    Assignee: Imperial Chemical Industries PLC
    Inventors: Robert A. Noon, Patrick J. Crowley, Diana M. Worthington
  • Patent number: 5266586
    Abstract: Fungicidal trazoles of the formula ##STR1## in which Ar stands for optionally substituted aryl,A stands for the groups ##STR2## and X stands for the groups ##STR3## wherein R.sup.1 stands for hydrogen or alkyl,R.sup.2 stands for hydrogen or alkyl,R.sup.3 stands for hydrogen, alkyl, alkenyl, alkanoyl, for optionally substituted cycloalkyl or for in each case optionally substituted aralkyl or aroyl,R.sup.4 stands for hydrogen, alkyl, for optionally substituted cycloalkyl or for in each case optionally substituted aralkyl or aryl andR.sup.5 and R.sup.6 independently of one another stand for alkyl or for optionally substituted aralkyl or together stand for an optionally substituted doubly-linked alkylene radical,and addition products thereof with acids and metal salts.
    Type: Grant
    Filed: May 14, 1992
    Date of Patent: November 30, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerd Kleefeld, Stefan Dutzmann
  • Patent number: 5266584
    Abstract: New Ethyl-triazolyl derivatives of the formula ##STR1## in which R represents halogen,X.sup.1 represents fluorine, chlorine or bromine,X.sup.2 represents fluorine, chlorine or bromine,Z represents halogen, alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, ethyl having 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkoxy having 1 or 2 carbon atoms and 1 to 5 halogen atoms, phenyl, phenoxy, nitro or alkoximinoalkyl having 1 to 4 carbon atoms in the alkoxy moiety and 1 to 4 carbon atoms in the alkyl moiety andm represents the numbers 0, 1, 2 or 3,and addition products thereof with acids or metal salts are very effective for combating fungi.
    Type: Grant
    Filed: April 2, 1993
    Date of Patent: November 30, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jurgen Scherkenbeck, Michael Lindemann, Stefan Dutzmann, Heinz-Wilhelm Dehne
  • Patent number: 5262543
    Abstract: The present invention discloses a process to produce a compound of the formula (IA): ##STR1## or an acid addition salt or metal complex thereof, in which n represents an integer from 0 to 5; each R represents a halogen atom, or a nitro, cyano, alkyl, haloalkyl or phenyl group; R.sup.1 and R.sup.2 independently represent a hydrogen atom or an alkyl group; and A represents a nitrogen atom or a CH group; which comprises steps of:(1) reacting a compound of the formula (IVA): ##STR2## with a compound of the formula (V): R.sup.3 SO.sub.2 X (V) in which n, R, R.sup.1 and R.sup.2 are as defined above and R.sup.3 represents a C.sub.1-4 alkyl group or a phenyl group each optionally substituted by one or more substituents selected from halogen atoms, nitro, cyano, hydroxyl, C.sub.1-4 alkyl, C.sub.1-4 haloalkyl, C.sub.1-4 alkoxy, C.sub.1-4 haloalkoxy; amino, C.sub.1-4 alkylamino, di-C.sub.1-4 alkylamino, C.sub.1-4 alkoxycarbonyl, carboxyl, C.sub.1-4 alkanoyl, C.sub.1-4 alkylthio, C.sub.1-4 alkylsulphinyl, C.sub.
    Type: Grant
    Filed: June 3, 1992
    Date of Patent: November 16, 1993
    Assignee: Kureha Kagaku Kogyu Kabushiki Kaisha
    Inventor: Paul H. Briner
  • Patent number: 5262434
    Abstract: New halogenoalkyl-azolyl derivatives of the formula ##STR1## in which R.sup.1 represents optionally substituted phenyl,R.sup.2 represents hydrogen, alkyl, alkenyl, acyl or aralkyl,X.sup.1 represents halogen,X.sup.2 represents halogen,n represents 0 or 1 andY represents nitrogen or a CH groupand their acid addition salts and metal salt complexes, are outstandingly effective as microbicides in plant protection and in the preservation of materials.
    Type: Grant
    Filed: August 14, 1992
    Date of Patent: November 16, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Manfred Jautelat, Jurgen Scherkenbeck, Klaus Stroech, Stefan Dutzmann, Heinz Dehne, Gerd Haenssler, Karl-Heinz Kuck
  • Patent number: 5252317
    Abstract: Disclosed are amplifier molecules: various organic compounds having branched structures terminating with amine groups to which pharmacologically active groups can be chemically attached. A number of MRI contrast-enhancing agents were synthesized, each comprising plural active groups, such as stable nitroxides and complexes of trivalent metal cations. Such syntheses were successfully performed using a number of amplifiers having different branched structures, demonstrating the general utility of the pertinent chemistry in the synthesis of amplifiers having any of a wide variety of pharmacologically active groups. Amplifiers were also synthesized having linkers terminating with chemically reactive groups such as isothiocyanates, which render the amplifier bifunctional: attachable to polymers, biomacromolecules, or other biocompatible entity possessing multiple reactive sites such as terminal amines.
    Type: Grant
    Filed: May 22, 1992
    Date of Patent: October 12, 1993
    Assignee: The State of Oregon Acting by and through the State Board of Higher Education on Behalf of the University of Oregon
    Inventor: John F. W. Keana
  • Patent number: 5252594
    Abstract: This invention relates to novel (2-aryl-2-substituted)ethyl-1,2,4-triazoles and the enantiomorphs, acid addition salts and metal salt complexes thereof, as well as their method of preparation and their use as highly active broad-spectrum systemic fungicides.
    Type: Grant
    Filed: June 17, 1992
    Date of Patent: October 12, 1993
    Assignee: Rohm and Haas Company
    Inventors: Steven H. Shaber, Katherine E. Flynn
  • Patent number: 5250555
    Abstract: 1-Halo-1-azolylmethane derivatives of the formula ##STR1## where A and R are each alkyl, benzyl, benzoyl, acyl, biphenylyl, naphthyl, hetaryl or phenyl, it being possible for each of these radicals to be substituted;D is Cl or Br,X is CH or N,and their plant-compatible acid addition salts and metal complexes are used as fungicides.
    Type: Grant
    Filed: September 23, 1991
    Date of Patent: October 5, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Seele, Norbert Goetz, Thomas Saupe, Gisela Lorenz, Eberhard Ammermann
  • Patent number: 5248683
    Abstract: Compounds of the formula ##STR1## in which A.sub.1 and A.sub.2 independently of one another are CO--C.sub.1 -C.sub.4 alkyl, COO--C.sub.1 -C.sub.4 alkyl, CO--CF.sub.3, CO--N(R).sub.2 or cyano;A.sub.1 and A.sub.2 together are CO(X).sub.n --C.sub.1 -C.sub.3 alkylene-(X).sub.n CO, CO(X).sub.n --C.sub.1 -C.sub.3 alkylene-(X).sub.n CO which is substituted by C.sub.1 -C.sub.4 alkyl, COOR, CON(R).sub.2, cyano or phenyl, it being possible for the phenyl ring, in turn, to be substituted by halogen, methyl, trifluoromethyl, methoxy, nitro or cyano; CO--N(R)--CO--N(R)--CO;R is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.6 alkenyl or C.sub.3 -C.sub.6 alkynyl;X is oxygen, sulfur or N(CH.sub.3);X.sub.1, X.sub.2 and X.sub.3 independently of one another are hydrogen, halogen, methyl, methylthio, methoxy or nitro;n is 0 or 1;including the salts of the compounds of the formula I with agriculturally acceptable organic or inorganic bases, and including the metal complexes; have valuable microbicidal properties.
    Type: Grant
    Filed: June 4, 1992
    Date of Patent: September 28, 1993
    Assignee: Ciba-Geigy Corporation
    Inventors: Hans-Georg Brunner, Walter Kunz, Rolf Schurter
  • Patent number: 5238808
    Abstract: A chemical moiety is disclosed which comprises a chemical, biochemical, or biological substance attached to one or more electrochemiluminescent organometallic compounds. In a preferred embodiment of the invention the substance is attached to one or more ruthenium-containing or osmium-containing luminescent organometallic compounds. Methods are disclosed for detecting very small amounts of the chemical moiety using chemiluminescent, electrochemiluminescent, and photoluminescent means. Compounds are disclosed which are useful for labelling substances of interest with ruthenium-containing and osmium-containing labels or other electrochemiluminescent labels. These labelled substances are useful in methods provided for detecting and quantifying analytes of interest in binding assays and competitive binding assays. The labelled substances are of particular use in homogeneous binding assays.
    Type: Grant
    Filed: October 24, 1985
    Date of Patent: August 24, 1993
    Assignee: Igen, Inc.
    Inventors: Allen J. Bard, George M. Whitesides
  • Patent number: 5221605
    Abstract: A chemical moiety is disclosed which comprises a chemical biochemical, or biological substance attached to one or more electrochemiluminescent organometallic compounds. In a preferred embodiment of the invention the substance is attached to one or more ruthenium-containing or osmiumcontaining luminescent organometallic compounds. Methods are disclosed for detecting very small amounts of the chemical moiety using chemiluminescent, electrochemiluminescent, and photoluminescent means. Compounds are disclosed which are useful for labelling substances of interest with ruthenium-containing and osmium-containing labels or other electrochemiluminescent labels. These labelled substances are useful in methods provided for detecting and quantifying analytes of interest in binding assays and competitive binding assays. The labelled substances are of particular use in homogeneous binding assays.
    Type: Grant
    Filed: October 30, 1990
    Date of Patent: June 22, 1993
    Assignee: Igen, Inc.
    Inventors: Allen J. Bard, George M. Whitesides
  • Patent number: 5220021
    Abstract: Unsaturated geminal phosphonates (III) ##STR1## either as the esters, free acids or salts are useful in the treatment of arthritis.
    Type: Grant
    Filed: September 6, 1991
    Date of Patent: June 15, 1993
    Assignee: The Upjohn Company
    Inventors: Colin J. Dunn, Richard A. Nugen
  • Patent number: 5219876
    Abstract: The invention provides compounds of formula I wherein R, R.sub.1 and Az are as defined in the description, the fungicidal use of such compounds, compositions for facilitating such use and the preparation of compounds of formula I.
    Type: Grant
    Filed: April 6, 1992
    Date of Patent: June 15, 1993
    Assignee: Sandoz Ltd.
    Inventor: Rupert Schneider
  • Patent number: 5216006
    Abstract: Fungicidal azolyl-propanols of the formula ##STR1## in which R represents halogenoalkyl, halogenoalkenyl, a 2-phenoxy-isopropyl radical, ##STR2## Y represents nitrogen or a CH group, Z represents halogen, alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, cyano, phenoxy, halo-phenoxy, or optionally substituted aryl,m represents the number 0, 1, 2, or 3, and addition products thereof with acids and metal salts.
    Type: Grant
    Filed: June 3, 1991
    Date of Patent: June 1, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Je,uml/u/ rgen Scherkenbeck, Thomas Himmler, Klaus Stroech, Stefan Dutzmann, Gerd Hanssler, Heinz-Wilhelm Dehne
  • Patent number: 5216010
    Abstract: N-Thiocyanatomethoxyazaheterocycles of the general formula INCS--CH.sub.2 --O--Het(where Het is pyrazolyl, imidazolyl or triazolyl, each of which may be substituted, or is indazolyl, benzoimidazolyl or benzotriazolyl, where each of the fused benzene rings may furthermore be substituted, and the salts and metal complexes thereof, with the exception of 1-[(thiocyanato)methoxy]-pyrazole, and biocides containing them.
    Type: Grant
    Filed: April 29, 1991
    Date of Patent: June 1, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Wolfgang Reuther, Ulf Baus, Gisela Lorenz
  • Patent number: 5216007
    Abstract: This invention relates to substituted ethylenic imidazoles and triazoles, their enantiomorphs, acid addition salts and metal complexes as well as their methods of preparation and use as broad spectrum systemic fungicides useful in controlling phytopathogenic fungi such as barley net blotch (Helminthosporium teres), bean powdery mildew (Erysiphe polygoni), peanut cercospora (Cercospora arachidicola), and wheat stem rust (Puccinia graminis f. sp. tritici race 15B-2).
    Type: Grant
    Filed: January 15, 1992
    Date of Patent: June 1, 1993
    Assignee: Rohm and Haas Company
    Inventors: George A. Miller, Hak-Foon Chan
  • Patent number: 5206232
    Abstract: The present invention concerns improved crystalline metal complexes of the fungicide 1-[N-propyl-N-2-(2,4,6-trichlorophenoxy)-ethyl carbamoyl]-imidazole, known by the common name prochloraz, its improved formulations and their use in combatting fungi, especially powdery mildew (Sphaerotheca fuliginia) and coffee berry disease (Colletotrichum coffeanum).
    Type: Grant
    Filed: March 1, 1991
    Date of Patent: April 27, 1993
    Assignee: Makhteshim Chemical Works Ltd.
    Inventors: Joseph Sharvit, Daniel Shohat, Yosef Gur
  • Patent number: 5204362
    Abstract: Azolylethane derivatives of the formula I ##STR1## where A and R.sup.1 are each alkyl, phenyl, biphenyl, naphthyl, benzyl, cycloalkyl, alkoxy, alkylthio, phenoxy, benzyloxy, phenylthio, methoxycarbonylethyl or hetaryl, these radicals being substituted or unsubstituted,D is halogen, alkoxy, alkylthio, phenylthio or phenoxy, these radicals being substituted or unsubstituted,X is CH or N,plant-tolerated acid addition salts and metal complex compounds thereof, and fungicides containing these compounds.
    Type: Grant
    Filed: March 26, 1991
    Date of Patent: April 20, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Seele, Norbert Goetz, Wolfgang Brox, Reiner Kober, Eberhard Ammermann, Gisela Lorenz
  • Patent number: 5204363
    Abstract: Triazole and imidazole compounds having the general formula (I): ##STR1## wherein R.sup.1 and R.sup.2, which may be the same or different, are hydrogen, alkyl, optionally substituted cycloalkyl, cycloalkylmethyl, alkenyl, heterocyclyl, aryl or aralkyl optionally substituted with halogen, nitro alkyl, haloalkyl, haloalkoxy, alkoxy, phenyl, phenoxy, benzyl, benzylosy, halophenyl or haloalkoxy; R.sup.3 is hydrogen, alkyl, alkenyl, alkynyl, aralkyl or acyl; R.sup.4 and R.sup.5, which may be the same or different, are hydrogen, alkyl, alkenyl or optionally substituted aryl; R.sup.6 and R.sup.7, which may be the same or different, are hydrogen, alkyl, alkenyl or optionally substituted aryl; X is oxygen or sulphur or is SO or SO.sub.2 ; and Az is 1,2,4- or 1,3,4-triazole or imidiazole ring; and isomers, acid addition salts and metal complexes thereof. The compounds are useful as plant fungicides.
    Type: Grant
    Filed: January 18, 1991
    Date of Patent: April 20, 1993
    Assignee: Imperial Chemical Industries PLC
    Inventors: Balasubramanyan Sugavanam, Paul A. Worthington, John M. Clough
  • Patent number: 5194444
    Abstract: Azolylmethyloxiranes of the general formula I ##STR1## where A and B are cycloalkyl, tetrahydropyranyl, tetrahydrofuranyl, dioxanyl, norbornyl, cycloalkenyl or phenyl, each of these radicals being unsubstituted or substituted, with the proviso that A and Z are not simultaneously phenyl, D is O, X is CH or N, and their plant-tolerated acid addition salts or metal complexes, and fungicides containing these compounds.
    Type: Grant
    Filed: February 11, 1992
    Date of Patent: March 16, 1993
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Seele, Stefan Karbach, Thomas Kuekenhoehner, Hubert Sauter, Gisela Lorenz, Eberhard Ammermann
  • Patent number: 5194626
    Abstract: Metal complexes of azines of the formula ##STR1## in which X denotes hydrogen or halogen,R denotes hydrogen or an organic radical,R.sub.1 denotes hydrogen or an organic radical,R.sub.2 denotes an organic radical, in which R.sub.1 and R.sub.2 together with the C atom linking them can also form a carbocyclic or heterocyclic ring or a carbocyclic or heterocyclic ring system in which the rings and ring systems mentioned can also be substituted, and one of the radicals R.sub.1, R.sub.2 or R.sub.1 and R.sub.2 together contain a group capable of forming a metal salt, and processes for pigmenting using these metal complexes.
    Type: Grant
    Filed: January 17, 1992
    Date of Patent: March 16, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Meinhard Rolf, Bernd Kaletta
  • Patent number: 5192783
    Abstract: This invention relates to 1 and 4-aralkyl-1,2,4-triazoles, their enantiomorphs, acid addition salts and metal salt complexes. This invention also relates to the method of preparation and use of these compounds. These compounds are highly active broad-spectrum systemic fungicides effective in controlling phytopathogenic fungi such as barley net blotch (Helminthosporium teres), grey mold (Botrytis cinerea), bean powdery mildew (Erysiphe polygoni), grape downy mildew (Plasmopora viticola), rice blast (Piricularia oryzae), tomato late blight (Phytophthora infestans) and wheat stem rust (Puccinia graminis f. sp. tritici race 15B-2).
    Type: Grant
    Filed: September 30, 1985
    Date of Patent: March 9, 1993
    Assignee: Rohm and Haas Company
    Inventors: George A. Miller, Hak-Foon Chan, Hak-Foon Chan
  • Patent number: 5190565
    Abstract: A new class of sulfonated 2-(2'-hydroxyaryl)-2H-benzotriazole compounds and method for using them and other sulfonated hydroxyaryl benzotriazoles on nylon fibers to improve stain resistance and dye lightfastness has been discovered. A process is provided for improving stain resistance of nylon fibers by treatment with sulfonated aromatic-formaldehyde condensate and fluorinated dry soil resist agents.
    Type: Grant
    Filed: February 1, 1991
    Date of Patent: March 2, 1993
    Assignee: Allied-Signal Inc.
    Inventors: Morris B. Berenbaum, John H. Bonfield, Charles J. Cole, Paul W. Harris, Thomas P. J. Izod, Harry E. Ulmer, Frederick R. Hopf, James T. Yardley, Karen M. Bland
  • Patent number: 5187178
    Abstract: Fungicidal triazoles of the formula ##STR1## in which Ar stands for optionally substituted aryl,A stands for the groups ##STR2## and X stands for the groups ##STR3## wherein R.sup.1 stands for hydrogen or alkyl,R.sup.2 stands for hydrogen or alkyl,R.sup.3 stands for hydrogen, alkyl, alkenyl, alkanoyl, for optionally substituted cycloalkyl or for in each case optionally substituted aralkyl or aroyl,R.sup.4 stands for hydrogen, alkyl, for optionally substituted cycloalkyl or for in each case optionally substituted aralkyl or aryl andR.sup.5 and R.sup.6 independently of one another stand for alkyl or for optionally substituted aralkyl or together stand for an optionally substituted doubly-linked alkylene radical,and addition products thereof with acids and metal salts.
    Type: Grant
    Filed: April 17, 1991
    Date of Patent: February 16, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Gerd Kleefeld, Stefan Dutzmann
  • Patent number: 5187172
    Abstract: Compounds having a 5 membered, nitrogen containing ring with a thione group adjacent to a nitrogen atom substituted with an OR group have antimicrobial properties. Metal complexes or salts of these compounds also have antimicrobial properties. The compounds, or the metal complexes or salts thereof, can be used as a cutting fluid preservative, a wood preservative, in cooling water applications or as an antimicrobial agent in a paint. Some of the compounds are new. The metal complexes or salts are new.
    Type: Grant
    Filed: February 18, 1992
    Date of Patent: February 16, 1993
    Assignee: Imperial Chemical Industries PLC
    Inventor: Peter W. Austin
  • Patent number: 5175169
    Abstract: New halogenovinyl-azole derivatives of the formula ##STR1## in which R.sup.1 represents optionally substituted alkyl, optionally substituted alkenyl, optionally substituted cycloalkyl or optionally substituted aryl, or represents optionally substituted heteroaryl,R.sup.2 represents hydrogen, alkyl, alkenyl, acyl or aralkylX.sup.1 represents halogen,X.sup.2 represents halogen,X.sup.3 represents hydrogen or halogenY represents nitrogen or a CH group,and acid addition salts and metal salt complexes thereofare very effective for combating microbes in plant protection and in the preservation of materials.
    Type: Grant
    Filed: September 17, 1991
    Date of Patent: December 29, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Manfred Jautelat, Dieter Berg, Stefan Dutzmann, Wilhelm Brandes, Gerd Hanssler, Astrid Mauler, Wilfried Paulus, Monika Frie
  • Patent number: 5175311
    Abstract: A chiral catalyst is disclosed together with methods of using it for enantioselective syntheses. The chiral catalyst includes a nucleus with two metal atoms that has four bridging ligands oriented radially to the axis of the nucleus. Each of these ligands includes two complexing atoms each complexed to one of the metal atoms. At least one of the bridging ligands includes a chiral center which is bonded to one of the complexing atoms. Preferably, all four of the bridging ligands include a chiral center bonded to one of the complexing atoms. The catalyst of the invention has been found to be useful in catalyzing carbenoid transformation reactions such as cyclopropanation.
    Type: Grant
    Filed: March 29, 1990
    Date of Patent: December 29, 1992
    Assignee: Research Corporation Technologies, Inc.
    Inventor: Michael F. Doyle
  • Patent number: 5171748
    Abstract: The invention concerns novel heterocyclic compounds of the formula I as defined herein and their physiologically acceptable salts, together with pharmaceutical compositions containing them. The heterocyclic compounds antagonize the actions of angiotensin II and are of value in treating diseases or medical conditions such as hypertension and congestive heart failure in warm-blooded animals. The invention further includes processes for the manufacture of the novel compounds and their use in medical treatment.
    Type: Grant
    Filed: May 22, 1990
    Date of Patent: December 15, 1992
    Assignee: Imperial Chemical Industries plc
    Inventors: David A. Roberts, Simon T. Russell
  • Patent number: 5164408
    Abstract: 1,2-Dihaloazolylethane derivatives of the general formula I ##STR1## where R.sup.1 and R.sup.2 are each substituted or unsubstituted phenyl, biphenyl, naphthyl or hetaryl, Z is chlorine or bromine, and X is CH or N, and their plant-tolerated acid addition salts and metal complexes, and fungicides and growth regulators containing these compounds.
    Type: Grant
    Filed: July 13, 1990
    Date of Patent: November 17, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Seele, Norbert Goetz, Walter Himmele, Reiner Kober, Wolfgang Rohr, Eberhard Ammermann, Gisela Lorenz, Wilhelm Rademacher, Johann Jung
  • Patent number: 5162357
    Abstract: and their acid addition salts and metal complexes,with the exception of 2-(imidazol-1-ylmethyl)-2-(4-fluorophenyl)-3-(pyrid-3-yl)-oxirane.The compounds I are suitable as fungicides.
    Type: Grant
    Filed: September 7, 1990
    Date of Patent: November 10, 1992
    Assignee: BASF Aktiengesellschaft
    Inventors: Rainer Seele, Norbert Goetz, Reiner Kober, Bernhard Zipperer, Eberhard Ammermann, Gisela Lorenz, Joachim Gebhardt
  • Patent number: 5162358
    Abstract: New halogenoalkyl-azolyl derivatives of the formula ##STR1## in which R.sup.1 represents optionally substituted alkyl, optionally substituted alkenyl or optionally substituted cycloalkyl,R.sup.2 represents hydrogen, alkyl, alkenyl, acyl or aralkyl,X.sup.1 represents halogen,X.sup.2 represents halogen,n represents 0 or 1 andY represents nitrogen or a CH group,and acid addition salts and metal salt complexes thereofare very effective for combating undesired microorganisms in plant protection and in the preservation of materials.
    Type: Grant
    Filed: July 30, 1991
    Date of Patent: November 10, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Manfred Jautelat, Jurgen Scherkenbeck, Klaus Stroech, Stefan Dutzmann, Heinz-Wilhelm Dehne, Gerd Hanssler, Harl-Heinz Kuck
  • Patent number: 5160527
    Abstract: A composition comprising:(a) A 3-isothiazolone compound(b) a stabilizing amount of a metal salt, said metal salts selected from the group where the cation is copper, zinc, manganese, ferrous or ferric, and the anion is selected from the group consisting of an organic carboxylic acid of at least of six carbon atoms, EDTA, 8-hydroxyquinolinate, gluconate, o-phenanthroline, quinolinate, N,N-bis(2-hydroxy-5-sulfobenzyl) glycine, lignosulfonate polymers, and polyacrylates; and(c) a locus to be protected against the growth of algae, bacteria, or fungi, selected from the group consisting of:(i) a metal working fluid (MWF) comprising at least one component selected from the group consisting of an alkanolamine, a petroleum sulfonate emulsifier, a boric acid ester or boric acid amide, a corrosion inhibitor, and a fatty acid;(ii) cooling tower water comprising corrosion inhibitors or scale inhibitors,(iii) laundry dish water;(iv) a cosmetic formulation;(v) a fuel system;(vi) an emulsion;(vii) a solid protective or decor
    Type: Grant
    Filed: May 24, 1991
    Date of Patent: November 3, 1992
    Assignee: Rohm and Haas Company
    Inventors: Andrew B. Law, Gary L. Willingham
  • Patent number: 5143932
    Abstract: Microbicidal halogenoallyl-azolyl derivatives of the formula ##STR1## in which R.sup.1 represents a radical of the formula ##STR2## R.sup.2 represents hydrogen, alkyl, alkenyl, acyl or aralkyl, X.sup.1 represents halogen,X.sup.2 represents halogen,X.sup.3 represents hydrogen or halogen andY represents nitrogen or a CH group,and addition products thereof with acids and metal salts.
    Type: Grant
    Filed: January 25, 1991
    Date of Patent: September 1, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Manfred Jautelat, Klaus Stroech, Gerd Hanssler, Stefan Dutzmann, Karl-Heinz Kuck, Wilhelm Brandes
  • Patent number: 5142061
    Abstract: The present invention discloses a process to produce a compound of the formula (IA): ##STR1## or an acid addition salt or metal complex thereof, in which n represents an integer from 0 to 5; each R represents a halogen atom, or a nitro, cyano, alkyl, haloalkyl or phenyl group; R.sup.1 and R.sup.2 independently represent a hydrogen atom or an alkyl group; and A represents a nitrogen atom or a CH group; which comprises steps of:(1-a) reacting a compound of the formula (VI): ##STR2## in which n,R,R.sup.1 and R.sup.2 are as defined above, with a reducing agent to obtain a compound of the formula (IVA); or, as an alternative step,(1-b) reacting a compound of the formula (VII): ##STR3## in which n, R,R.sup.1 and R.sup.2 are as defined above and R.sup.5 represents a hydrogen atom or an alkyl group,with a reducing agent to obtain a compound of the formula (IVA);(2) reacting a compound of the formula (IVA): ##STR4## with a compound of the formula (V):R.sup.3 SO.sub.2 X (V)in which n,R,R.sup.1 and R.sup.
    Type: Grant
    Filed: October 1, 1990
    Date of Patent: August 25, 1992
    Assignee: Kureha Kagaku Kabushiki Kaisha
    Inventor: Paul H. Briner
  • Patent number: 5140035
    Abstract: Fungicidal triazolylmethyl-cyclopropyl derivatives of the formula ##STR1## in which R represents a radical of the formula ##STR2## in which Z represents halogen, alkyl having 1 to 4 carbon atoms, alkoxy having 1 to 4 carbon atoms, alkylthio having 1 to 4 carbon atoms, halogenoalkyl having 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkoxy having 1 or 2 carbon atoms and 1 to 5 halogen atoms, halogenoalkylthio having 1 or 2 carbon atoms and 1 to 5 halogen atoms, phenyl which is optionally substituted by at least one of alkyl having 1 or 2 carbon atoms and halogen, or represents phenoxy which is optionally substituted by at least one of alkyl having 1 or 2 carbon atoms and halogen, andm represents the numbers 0, 1, 2 or 3,R.sup.1 represents halogen, alkyl having 1 to 4 carbon atoms or alkoxy having 1 to 4 carbon atoms,n represents the numbers 0, 1 or 2,R.sup.
    Type: Grant
    Filed: December 17, 1990
    Date of Patent: August 18, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventors: Jurgen Scherkenbeck, Klaus Stroech, Burghard Fugmann, Stefan Dutzmann
  • Patent number: 5135825
    Abstract: There is disclosed a method for producing an ambient temperature molten salt comprising at least one of 1,3-dialkylimidazolium halide, 1,2,3-trialkylimidazolium halide and N-alkylpyridinium halide, and an aluminum halide, which comprises suspending the above starting materials in an inert solvent having a low boiling point to carry out a complex forming reaction.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: August 4, 1992
    Assignees: Mitsubishi Petrochemical Co., Ltd., Nisshin Steel Co., Ltd.
    Inventors: Shoichiro Mori, Kazuhiko Ida, Hitoshi Suzuki, Setsuko Takahashi, Isao Saeki
  • Patent number: 5135737
    Abstract: Disclosed are amplifier molecules: various organic compounds having branched structures terminating with amine groups to which pharmacologically active groups can be chemically attached. A number of MRI contrast-enhancing agents were synthesized, each comprising plural active groups, such as stable nitroxides and complexes of trivalent metal cations. Such syntheses were successfully performed using a number of amplifiers having different branched structures, demonstrating the general utility of the pertinent chemistry in the synthesis of amplifiers having any of a wide variety of pharmacologically active groups. Amplifiers were also synthesized having linkers terminating with chemically reactive groups such as isothiocyanates, which render the amplifier bifunctional: attachable to polymers, biomacromolecules, or other biocompatible entity possessing multiple reactive sites such as terminal amines.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: August 4, 1992
    Assignee: The State of Oregon Acting by and through the State Board of Higher Education on behalf of the University of Oregon
    Inventor: John F. W. Keana