Abstract: A monitoring device configured to be attached to the ear of a person includes a base, an earbud housing extending outwardly from the base that is configured to be positioned within an ear of a subject, and a cover surrounding the earbud housing. The base includes a speaker, an optical emitter, and an optical detector. The cover includes light transmissive material that is in optical communication with the optical emitter and the optical detector and serves as a light guide to deliver light from the optical emitter into the ear canal of the subject wearing the device at one or more predetermined locations and to collect light external to the earbud housing and deliver the collected light to the optical detector.

Abstract: According to various embodiments, a regional oximetry sensor may include a light emitting element configured to emit light, a light detector configured to receive the light and generate a signal based on the received light. The regional oximetry sensor, itself or in conjunction with a monitor, may enable communicating adjustments in the administration of CPR to a patient based on one or more characteristics (e.g., pulse amplitude or pulse rate) of the signal generated by the regional oximetry sensor.

Abstract: A system and method for measuring one or more light-absorption related blood analyte concentration parameters of a mammalian subject, is disclosed. In some embodiments, the system comprises: a) a photoplethysmography (PPG) device configured to effect a PPG measurement by illuminating skin of the subject with at least two distinct wavelengths of light and determining relative absorbance at each of the wavelengths; b) a dynamic light scattering measurement (DLS) device configured to effect a DLS measurement of the subject to rheologically measure a pulse parameter of the subject; and c) electronic circuitry configured to: i) temporally correlating the results of the PPG and DLS measurements; and ii) accordance with the temporal correlation between the PPG and DLS measurements, assessing value(s) of the one or more light-absorption related blood analyte concentration parameter(s).

Abstract: Medical devices, plug-ins, systems, and methods for CPR quality feedback are disclosed. The medical devices can calculate peripheral circulation relevant parameters based on measured signals containing at least partial hemodynamic characteristics. Amplitude and area characteristics included in the peripheral circulation relevant parameters can further be determined for providing feedback and control relating to CPR quality during the compression process. Also, compression interruption during CPR can be evaluated based on a pulse waveform generated from the measured signals.

Abstract: Methods and systems are presented for triggering physiological measurements in a physiological monitor. Metrics are computed for a received physiological signal (e.g., a PPG signal), or a determined physiological parameter associated with the physiological signal (e.g., blood pressure). A change parameter is determined based on one or more of the metrics, and a variable change threshold is determined. The variable change threshold may be determined over time based on a time measure, a frequency measure, or both. The change parameter is compared to the variable change threshold, and a physiological measurement is triggered based on the comparison. The variable change threshold technique may allow measurements to be taken frequently enough to catch clinically significant changes in a physiological parameter of a subject but not so often as to interfere with the subject's comfort or the function of other medical monitors.

Abstract: Systems, methods, and computer executable instructions for monitoring a patient's cardiopulmonary status and/or providing feedback-based control regarding the same. Such methods include, and such systems are configured for, determining a cardiopulmonary status based upon measured data, e.g., from a plurality of sensors, comparing the determined cardiopulmonary status with input data, e.g., input data indicating a target cardiopulmonary status, and providing a result signal based upon the comparison. The result signal may include a display signal for displaying an indication of the result of the comparison, an audio alert signal for audibly provided an indication of the result of the comparison, and/or a control signal for controlling an exercise apparatus in accordance with the result of the comparison.

Abstract: Various embodiments of methods and systems for continuous transdermal monitoring (“CTM”) are disclosed. One exemplary embodiment of a continuous transdermal monitoring system comprises a sensor package. The sensor package may include a pulse oximetry sensor having a plurality of light detectors arranged as an array. One exemplary method for continuous transdermal monitoring begins by positioning a pulse oximetry sensor system, similar to the system described immediately above, adjacent to a target tissue segment. Then, the method continues by detecting a light reflected by the target tissue segment. Then, the method continues by transmitting a pulse oximetry reading(s), based at least in part on the light reflected by the target tissue segment, of the target tissue segment. Then, the method continues by analyzing the pulse oximetry reading(s).

Abstract: A dual-spectra pulse oximeter sensor is provided. The dual-spectra pulse oximeter sensor includes a sensor substrate, an array of a plurality of pairs of wavelength sources disposed on the sensor substrate, and a plurality of wavelength conversion devices. Further, each pair of the plurality of pairs of wavelength sources comprises a pair of light emitting diodes. Moreover, one light emitting diode of each pair of light emitting diodes is operatively coupled to a wavelength conversion device of the plurality of wavelength conversion devices.

Abstract: The present invention generally relates to a non-invasive biosensor device configured to measure physiological parameters of a subject. In one aspect, a method of determining a training threshold of a subject is provided. The method includes the step of detecting an oxygenation parameter of a tissue of the subject using Near InfraRed Spectroscopy (NIRS). The method further includes the step of processing the oxygenation parameter. Additionally, the method includes the step of determining the training threshold of the subject using the result of the processing. In another aspect, a biosensor device for determining a lactate threshold of a subject during exercise is provided. In a further aspect, a biosensor device for measuring parameters of a subject during exercise is provided.

Abstract: Cardiac output is measured using a non-invasive method comprised of administering hyperbaric of hypoxic gas to the subject then after a time measuring the resultant changes in central or peripheral oxygen saturation times using a pulse oximeter located at a peripheral body site. Preferably the device is portable and is comprised of a gas cartridge, with one or more doses, and a mouth-piece, a microprocessor for performing the analysis, a pulse oximeter probe and a display for reporting the cardiac output.

Abstract: An embodiment of the present disclosure seeks to smooth a perfusion index measurement through use of a baseline perfusion index measurement and/or through the use of multiple PI calculations. The combination of the baseline perfusion index measurement reduces an error between a calculated measurement of PI and actual conditions.

Abstract: A mobile blood pressure monitor is described that includes an integrated acoustic device, an optical sensor including at least one of a light source or a pulse oximeter device, and control circuitry coupled to the integrated acoustic device and the optical sensor. Additionally, a mobile electronic device configured to measure blood pressure is described that includes a mobile system and a mobile blood pressure monitor as disclosed above. In implementations, a process for measuring blood pressure includes sensing a heart sound with an integrated acoustic device, measuring a blood pulse rate at a peripheral site with an optical sensor, calculating a pulse wave transit time using a sensed heart sound and a measured blood pulse rate, and correlating a blood pressure using the heart sound and the blood pulse rate.

Abstract: A system and method for evaluating a circulatory function of an individual includes at least one connection configured to receive signals indicative of functional data relating to at least one functional parameter of the cardiovascular system of the subject and to at least two disparate locations on the subject. A processor is coupled to the at least, one connection and configured to receive the functional data from the at least one connection. The processor is also configured to compare the functional data to identify variations that deviate from an expected delay associated with the disparate locations and provide an assessment of the cardiovascular system function based on the comparison of the functional data.

Abstract: A method and apparatus for determining a cardiovascular parameter including receiving an input signal corresponding to an arterial blood pressure measurement over an interval that covers at least one cardiac cycle, determining a propagation time of the input signal, determining at least one statistical moment of the input signal, and determining an estimate of the cardiovascular parameter using the propagation time and the at least one statistical moment.

Abstract: According to embodiments, techniques for determining respiratory parameters are disclosed. More suitable probe locations for determining respiratory parameters, such as respiration rate and respiratory effort, may be identified. The most suitable probe location may be selected for probe placement. A scalogram may be generated from the detected signal at the more suitable location, resulting in an enhanced breathing band for determining respiratory parameters. Flexible probes that allow for a patient's natural movement due to respiration may also be used to enhance the breathing components of the detected signal. From the enhanced signal, more accurate and reliable respiratory parameters may be determined.

Abstract: Real-time, short-term analysis of ECG, by using multiple signal processing and machine learning techniques, is used to determine counter shock success in defibrillation. Combinations of measures when used with machine learning algorithms readily predict successful resuscitation, guide therapy and predict complications. In terms of guiding resuscitation, they may serve as indicators and when to provide counter shocks and at what energy levels they should be provided as well as to serve as indicators of when certain drugs should be provided (in addition to their doses). For cardiac arrest, the system is meant to run in real time during all current resuscitation procedures including post-resuscitation care to detect deterioration for guiding care such as therapeutic hypothermia.

Abstract: The present disclosure may provide a system and method for analyzing data acquired using a physiological monitor. In one embodiment, the analysis is performed on the physiological monitor and results in the analysis of data collected by the physiological monitor over an interval of time. The analysis may include comparing the data to sample data representative of known disease states and/or may include performing statistical analyses or recalculations of the data based on adjusted monitor settings. In one embodiment, the settings of the physiological monitor may be adjusted based on the results of the analyses.

Abstract: The invention is directed to a system for acquiring electrical footprint of the heart, electrocardiogram (EKG or ECG), heart sound, heart rate, nasal airflow and pulse oximetry incorporated into a mobile device accessory. The ECG and heart sound signals are conveniently acquired and transmitted to a server via the mobile device, offering accurate heart failure analysis, and sleep disorder breathing indication.

Abstract: A tissue profile wellness monitor measures a physiological parameter, generates a tissue profile, defines limits and indicates when the tissue profile exceeds the defined limits. The physiological parameter is responsive to multiple wavelengths of optical radiation after attenuation by constituents of pulsatile blood flowing within a tissue site. The tissue profile is responsive to the physiological parameter. The limits are defined for at least a portion of the tissue profile.

Abstract: An in vivo monitoring method in a laparoscope system is provided. An object image is sequentially created with expression of a surface color of an object in a body cavity. A lock area (specific area) is determined within the object image, the lock area being movable by following motion of the object. A monitor image including a graph of oxygen saturation is generated according to a part image included in the object image and located in the lock area. The monitor image is displayed. Preferably, the oxygen saturation of the lock area is acquired according to two spectral data with respect to wavelengths of which an absorption coefficient is different between oxidized hemoglobin and reduced hemoglobin in data of the object image. The object is constituted by a blood vessel.

Abstract: A system and method are provided for using an oximeter to take blood pressure readings for an extended period of time. Calibration of the oximeter for this purpose requires use of a sphygmomanometer to determine a sequence of blood pressure readings taken for a patient over a sphygmomanometer duty cycle. During the duty cycle, readings for both blood pressure (sphygmomanometer) and blood flow amplitude (oximeter) are taken simultaneously at predetermined time intervals (e.g. patient pulse rate). These readings then determine an operational ratio between the two that can be used to translate pulse magnitude readings of the oximeter for presentation as blood pressure readings. Operationally, variations from the patient's systolic pressure can then be continuously monitored in real time.

Abstract: Devices and methods for sleep detection involve the use of an adjustable threshold for detecting sleep onset and termination. A method for detecting sleep includes adjusting a sleep threshold associated with a first sleep-related signal using a second sleep-related signal. The first sleep-related signal is compared to the adjusted threshold and sleep is detected based on the comparison. The sleep-related signals may be derived from implantable or external sensors. Additional sleep-related signals may be used to confirm the sleep condition. A sleep detector device implementing a sleep detection method may be a component of an implantable pulse generator such as a pacemaker or defibrillator.

Abstract: Disclosed is a fingerstall oximeter comprising an upper housing (11), a middle housing (12), a lower housing (13) and a detection unit. The upper housing (11), the middle housing (12) and the lower housing (13) are connected in turn. The lower housing (13) is made of silica gel, and a finger accommodating chamber (14) for accommodating a finger to be measured is formed between the opposed surfaces of the lower housing (13) and the middle housing (12). The fingerstall oximeter has high measurement accuracy and small volume, and is easy to disassemble and carry.

Abstract: A biological information detector includes a wristband, a light-emitting part, a reflecting part, a light-receiving part, a protecting part, an acceleration sensor and a processing part. The wristband is adapted to be attached to a body of a user. The light-emitting part is configured to emit green light. The reflecting part is configured to reflect the light emitted by the light-emitting part. The light-receiving part is configured to receive reflected light reflected at a detection site of the body of the user. The protecting part is configured to protect the light-emitting part, the protecting part having a contact surface configured to contact with the detection site. The acceleration sensor is configured to detect acceleration generated by the user. The processing part is configured to process a light reception signal outputted from the light-receiving part.

Abstract: A living body optical measurement apparatus of the present invention includes: a light irradiation/measurement unit for irradiating light to an object and measuring the light passed through the object, a signal processing unit for processing measurement data of the light irradiation/measurement unit and creating a living body optical measurement image, and a position measurement unit for measuring positions where light is irradiated to an object and where the passing light is extracted from the object, the light irradiation/measurement unit includes plural optical fibers. The light irradiation/measurement unit includes plural optical fibers, plural optical fiber plugs attached to the plural optical fibers respectively, and a holder fixed detachably at a measurement site of an object and holds the plural optical fiber plugs.

Abstract: The present invention involves a method and an apparatus for analyzing measured signals, including the determination of a measurement of correlation in the measured signals during a calculation of a physiological parameter of a monitored patient. Use of this invention is described in particular detail with respect to blood oximetry measurements.

Abstract: A system for measuring of arterial and venous blood constituent concentration based first on measuring cardiac blood flow balance parameter between the right chamber of the heart and the left chamber of the heart, which includes a sensor device for measuring one of blood pressure and blood flow rate and blood constituent concentration of a patient so as to generate an arterial pulse signal. A processing unit is responsive to the arterial pulse signal for generating full arterial pulse plethysmography waveforms, arterio-venous pulse plethysmography waveforms, and balance parameters. A computational device that is responsive to plethysmography waveforms generating a plurality of state space linear transfer functions by applying system identification between plethysmography waveforms at various wavelengths representing a plurality of models of the blood constituent concentration, including oxygen, carbon dioxide, hemoglobin, and glucose, and displaying related useful information.

Abstract: A physiological monitoring system may receive a sensor signal from a physiological sensor. The system may generate an estimate of the sensor signal based on, for example, prior received signals. The estimate signal may be subtracted from the sensor signal using a transimpedance amplifier to generate a difference signal. A gain and/or offset may be applied to the difference signal by the amplifier. The amplified difference signal may be digitized and combined with the estimate signal to generate a high resolution digital representation of the sensor signal. Physiological information such as blood oxygen saturation, pulse rate, respiration rate, respiration effort, blood pressure, hemoglobin concentration, any other suitable physiological parameters, or any combination thereof, may be determined using the digitized sensor signal.

Abstract: A method of analyzing a physiological (e.g., an ECG) signal during application of chest compressions. The method includes acquiring a physiological signal during application of chest compressions; acquiring the output of a sensor from which information on the velocity of chest compressions can be determined; and using the information on the velocity to reduce at least one signal artifact in the physiological signal resulting from the chest compressions.

Abstract: The present invention involves a method and an apparatus for analyzing measured signals, including the determination of a measurement of correlation in the measured signals during a calculation of a physiological parameter of a monitored patient. Use of this invention is described in particular detail with respect to blood oximetry measurements.

Abstract: The present disclosure provides a method and system for stimulating and monitoring intensity of pain experienced by one or more users. The method includes measuring the intensity of pain experienced by the one or more users on a pre-determined scale and augmented chart or physician's personal assessment using a plurality of one or more bio-markers, determining co-relation between the plurality of one or more bio-markers and the intensity of pain experienced by the one or more users, refining the co-relation between the plurality of one or more bio-markers and the intensity of pain experienced by the one or more users by learning from responses of one or more similar users, generating a pain profile for each of the one or more users and utilizing the learned information and the generated profile for monitoring, evaluating and treating the one or more users.

Abstract: Embodiments of the present disclosure provide systems and methods for monitoring a patient to produce a signal representing a blood oxygen concentration. The signal may be analyzed to determine the presence of one or more sleep apnea events, and an integral of the signal may be calculated if the signal is outside of a set range or threshold. A practitioner may choose to be informed of the presence of sleep apnea events if the blood oxygen concentration is less then a preset limit, if an upper limit has been reached for an integral representing the severity of the oxygen deprivation over time, or anytime sleep apnea events may be present in the signal.

Abstract: An integrated circuit device includes an insulating body provided with a number of electrically conductive leads and having a surface provided with a red LED aperture, an IR LED aperture and a photodetector aperture. The insulating body also includes an optical isolator optically separating the photodetector aperture from the red LED aperture and the IR LED aperture. A red LED is aligned with the red LED aperture, an IR LED is aligned with the IR LED aperture, and a photodetector is aligned with the photodetector aperture.

Abstract: A flexible sensor pad includes a cavity to hold a sensor unit with an attached cable. According to one aspect of the present invention, a light-shielding layer is coupled to a bottom surface of the sensor pad, surrounds the sensor unit, and extends past two sides of the sensor pad. A transparent adhesive layer is coupled to the light-shielding layer and extends past two sides of the light-shielding layer. Another light shielding layer is coupled to a top surface of the sensor pad and covers the sensor unit. The cable divides the sensor pad into a first side and a second side which are mirror images of each other.

Abstract: Systems and methods for detecting untoward clinical states (e.g., hypoperfusion) and classifying patient state based on at least one calculated physiological parameter are provided. The patient state classification may be used by a physician to determine patient condition and relative risk to guide decision making during a procedure.

Abstract: Aspects of the present disclosure include a sensor configured to store in memory indications of sensor use information and formulas or indications of formulas for determining the useful life of a sensor from the indications of sensor use information. A monitor connected to the sensor monitors sensor use and stores indications of the use on sensor memory. The monitor and/or sensor compute the useful life of the sensor from the indications of use and the formulas. When the useful life of the sensor is reached, an indication is given to replace the sensor.

Abstract: A biometric monitoring device having a heart rate sensor for measuring various biometric information is provided. In some embodiments, the biometric monitoring device allows the person to take and/or display a heart rate reading by a simple user interaction with the device, e.g., by simply touching a heart rate sensor surface area, moving the device in a defined motion pattern, or clenching the fist. Some embodiments of this disclosure provide a biometric monitoring device that allows a person to get a quick heart rate reading without removing the device or interrupting their other activities. Some embodiments provide heart rate monitoring with other desirable features such as feedback on data acquisition status.

Abstract: A device for non-invasively measuring at least one parameter of a cardiac blood vessel in a patient is provided. The device comprises at least one light source that emits light in the 400 nm to 1000 nm wavelength range; at least one photodetector adapted to receive light emitted by the light source and generate an output based on the received light, wherein said light is reflected from or transmitted through tissue of the patient, the output of said photodetector being correlated with a parameter of the blood vessel; and at least one probe for facilitating delivery of light from the light source to an external tissue site on the patient in the proximity of the cardiac blood vessel and receipt of light by the photodetector. A system and methods of monitoring/measuring cardiac parameters utilizing the device and/or system are also provided.

Abstract: An exercise and communications system includes an interactive device, a remote device, and an external device, wherein the interactive device is configured to gather data relating to a user of the system and transmit the same to the remote device, and the remote device is configured to provide analyze the data and transmit a response to the interactive device, which in turn communicates the response to the user and additionally communication with an external device for retrieval of instructions, programs, and data, inter alia. An exercise and communications system facilitates communication between a plurality of users, each having an interactive device and a remote device.

Abstract: A method and device is described, which measures and records one or more repetitive biological signals, such as heartbeat, breathing rate, and/or intrinsic brainwave frequency, and uses these tempos and timing information as a feedback mechanism to an individual doing one or more repetitive motion activities, in order to synchronize the activities with the repetitive biological signals, or a simple ratio of harmonics or sub-harmonics thereof. The feedback is achieved through a visual, audio, or tactile signal that indicates to the individual pacing information for precisely when to perform the activity. The purpose of synchronizing repetitive motion activity to biological activity is to optimize the efficiency of the system as a whole, reducing energy consumption and promoting calm and focused performance. Repetitive motion activities include but are not limited to breathing, running, bicycling, swimming, walking, hiking, jump rope, and rowing.

Abstract: A portable electronic device for providing a plurality of operation modes, emits light to an object to be sensed via a light source and senses reflected light from the object to be sensed via an optical sensor to generate a sensing signal. Based on this sensing signal, various functions can be performed, for example, remote control, proximity sensing, gesture sensing, hear rate sensing, blood oxygen saturation sensing, exhaled gas alcohol concentration sensing. The portable electronic device provided by the present invention integrate various functions therein and can measure various kinds of physiological parameters, thus is more convenient and helpful for many users.

Abstract: A single use, self-contained, self-powered disposable oximeter, in the form of a patch or a bandage strip, has mounted thereto a light emitter and a light sensor to measure the SpO2 of the patient. Mounted to an electronics layer of the patch is an application specific integrated circuit (ASIC) that has electronics integrated thereto that controls the operation of the light emitter and light sensor, and the algorithm for calculating from the data collected by the sensor at least the SpO2 of the patient. The patch oximeter may also be equipped with a transceiver, and the appropriate electronics, for wirelessly transceiving information to/from a remote device or another wireless patch oximeter.

Abstract: There is provided a measurement device including a measurement unit configured to have a light source unit configured to emit measurement light having at least one kind of wavelength for measuring a biological component included inside a living body, a detection unit configured to detect the measurement light emitted from the inside of the living body, and a polarization control unit configured to be provided in at least one position between the light source unit and the living body or between the living body and the detection unit and to control a polarization direction of the measurement light, and an analysis unit configured to compute an optical rotation degree based on a change in a polarization state of the measurement light using a measurement result obtained by the measurement unit and to analyze a concentration of the biological component based on the computed optical rotation degree.

Abstract: A cardiovascular risk evaluation apparatus includes a hypoxic acquisition unit for acquiring a measurement result that includes a blood oxygen saturation level measured in a hypoxic period in which the blood oxygen saturation level of a subject is lower than a threshold value, and a blood pressure measured when the blood oxygen saturation level was measured; a non-hypoxic acquisition unit for acquiring a measurement result that includes a blood oxygen saturation level measured in a non-hypoxic period of the blood oxygen saturation level of the subject, and a blood pressure measured when the blood oxygen saturation level was measured; and an indicator acquisition unit for acquiring a cardiovascular risk evaluation indicator for the subject based on the relationship between blood oxygen saturation level and blood pressure, which is based on the measurement results acquired by the hypoxic acquisition unit and the non-hypoxic acquisition unit.

Abstract: A method and apparatus for determining a venous oxygen saturation value (SvO2) of a subject is provided. The method includes the steps of: a) sensing a plurality of tissue regions on a subject using a NIRS oximeter adapted to determine a tissue oxygen saturation value (StO2) for each region, each region independent of the other regions and each region sensed using a NIRS oximeter sensor specific to that region, and determining a StO2 value for that region; b) assigning a coefficient to each region, each of which coefficients reflects a portion of the StO2 value for the region attributable to a composite venous blood return representative of the tissue regions measured; and c) determining a composite SvO2 value for the subject using the StO2 region values and the respective coefficients.

Abstract: Embodiments of the present invention include systems and methods that relate to pulse oximetry. Specifically, one embodiment includes an oximeter sensor comprising a light emitting element configured to emit light, a light detector configured to detect the light, and a memory chip having a built-in trimmed resistor, the trimmed resistor having a resistance value that is detectable by a monitor.

Abstract: A measurement device according to the present disclosure includes a light source which emits at least one kind of measurement light belonging to a predetermined wavelength band toward a measurement region formed of at least part of a living body, a detection unit in which a plurality of sensors is regularly arranged in a predetermined arrangement and which detects the measurement light emitted from the light source and passing through the living body with the plurality of sensors, and an analysis unit which performs analysis processing of specifying a measurement position for measuring information on pulsation along with activities of the living body from the measurement region based on a temporal change in an amount of light of the detected measurement light by use of a detection result detected by the detection unit.

Abstract: Provided according to embodiments of the present invention are pulse oximetry systems that include a pulse oximeter sensor, and a probe identification circuit that includes a thermistor. The probe identification circuit may be part of or associated with the pulse oximeter sensor.

Abstract: A transform for determining a physiological measurement is disclosed. The transform determines a basis function index from a physiological signal obtained through a physiological sensor. A basis function waveform is generated based on basis function index. The basis function waveform is then used to determine an optimized basis function waveform. The optimized basis function waveform is used to calculate a physiological measurement.

Abstract: A notification signal, intended to be received by a wireless communication device, is repetitively broadcast by a portable activity-monitoring device that generates user-activity data corresponding to activity of an individual bearing the portable activity-monitoring device. The notification signal conveys information that identifies the portable activity-monitoring device and indicates whether or not the portable activity-monitoring device seeks establishment of a wireless communication link to enable transmission of the user-activity data to the wireless communication device.