Determining Blood Constituent Patents (Class 600/322)
  • Patent number: 10702173
    Abstract: A system and method for camera-based heart rate tracking. The method includes: determining bit values from a set of bitplanes in a captured image sequence that represent the HC changes; determining a facial blood flow data signal for each of a plurality of predetermined regions of interest (ROIs) of the subject captured by the images based on the HC changes; applying a band-pass filter of a passband approximating the heart rate to each of the blood flow data signals; applying a Hilbert transform to each of the blood flow data signals; adjusting the blood flow data signals from revolving phase-angles into linear phase segments; determining an instantaneous heart rate for each the blood flow data signals; applying a weighting to each of the instantaneous heart rates; and averaging the weighted instantaneous heart rates.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: July 7, 2020
    Assignee: NuraLogix Corporation
    Inventors: Kang Lee, Evgueni Kabakov, Phil Levy
  • Patent number: 10705139
    Abstract: A semiconductor device inspection system (1) includes a laser beam source (2), for emitting light, an optical sensor (12) for detecting the light reflected by the semiconductor device (10) from the light and outputting a detection signal, a frequency band setting unit (16) for setting a measurement frequency band and a reference frequency band with respect to the detection signal, a spectrum analyzer (15) for generating a measurement signal and a reference signal from the detection signals in the measurement frequency band and the reference frequency band, and a signal acquisition unit (17) for calculating a difference between the measurement signal and the reference signal to acquire an analysis signal. The frequency band setting unit (16) sets the reference frequency band to a frequency domain in which a level of the detection signal is lower than a level obtained by adding 3 decibels to a white noise level serving as a reference.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: July 7, 2020
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventor: Tomonori Nakamura
  • Patent number: 10695005
    Abstract: The present invention discloses a non-invasive blood glucose measurement method, applied to noninvasive blood glucose measuring instruments including measuring hosts and fingertip measuring probes, comprising pre-storing a random forest algorithm and a neural network prediction algorithm in the measuring host; measuring energy metabolism parameters of a fingertip of an individual to be measured and transmitting the parameters to the measuring host by the fingertip measuring probe; calling the random forest algorithm to predict the blood glucose type of the energy metabolism parameters of the fingertip of the individual to be measured and calling the corresponding neural network prediction algorithm to calculate the blood glucose value of the fingertip of the individual to be measured by the measuring host. The present invention also provides a fingertip-measuring probe.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: June 30, 2020
    Assignees: Guilin Medicine Electronic Technology Co., Ltd., Guilin University of Electronic Technology
    Inventors: Zhencheng Chen, Jianming Zhu, Yongbo Liang, Shimin Yin, Guocheng Han, Biao Xu, Yang Zhang
  • Patent number: 10691072
    Abstract: A wearable device can include an electronic device and a band for securing the electronic device to the user. The electronic device can detect an identification of the band, which can serve as an input to initiate actions performed by the electronic device. For example, a type, model, color, size, or other characteristic of a band can be determined and used to select a corresponding action performed by the electronic device. Identification of the band can be performed by components of the electronic device that also serve other purposes. Existing sensors, communication elements, and/or detectors can be used to detect and identity a band provided to the electronic device. The electronic device can respond to the identification of a particular band by performing particular functions, such as changing an aspect of a user interface or altering settings of the electronic device.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: June 23, 2020
    Assignee: Apple Inc.
    Inventor: Timothy M. Johnson
  • Patent number: 10674962
    Abstract: A finger clamping device and an oximeter using the finger clamping device are provided. The finger clamping device includes a shell, an upper clamping member, and a lower clamping member. The shell includes two oppositely facing sidewalls. Each sidewall defines at least one sliding rail. The upper clamping member is arranged in the shell and defines two guiding rods. The two guiding rods are received in and slide along the sliding rail. At least one elastic member joins the lower clamping member and the upper clamping member and is tensioned when a finger is inserted between the upper clamping member and the lower clamping member.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: June 9, 2020
    Assignee: Hangzhou Jiangyu Innovation Medical Technology CO., LTD
    Inventors: Zhan-Sheng Lu, Yu-Chun Sun
  • Patent number: 10660551
    Abstract: A concentration measurement apparatus measures a temporal relative change amount (?cHb, ?O2Hb) of either or both of total hemoglobin concentration and oxygenated hemoglobin concentration in the head that vary due to repetition of chest compression, and includes a light incidence section making measurement light incident on the head, a light detection section detecting the measurement light propagated through the interior of the head and generating a detection signal in accordance with the intensity of the measurement light, and a CPU determining, based on the detection signal, the relative change amount (?cHb, ?O2Hb) and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount (?cHb, ?O2Hb).
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 26, 2020
    Assignees: ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE, HAMAMATSU PHOTONICS K.K.
    Inventors: Yasuaki Koyama, Takeo Ozaki, Susumu Suzuki
  • Patent number: 10649308
    Abstract: A coherent photon analog-to-digital conversion device comprising an optical clock oscillation source, a sampled signal source, a photon sampling gate, a photoelectric detection module, an electrical sampling module, a phase detection module, a loop filter, and signal feedback links. By adjusting the optical clock oscillating source or the sampled signal source, the invention makes the two highly coherent, thereby reducing the clock jitter and greatly improving the sampling precision. It is very important for improving the performance of microwave photon systems that require high time accuracy and high sampling accuracy, such as microwave photon radar and optical communication systems.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: May 12, 2020
    Assignee: Shanghai Jiao Tong Technology
    Inventors: Weiwen Zou, Guang Yang, Lei Yu, Na Qian, Jianping Chen
  • Patent number: 10635926
    Abstract: An image analyzing apparatus reprojects an input image in a plurality of different directions to divide the input image into a plurality of partial images, extracts a feature amount from each of the partial images, and calculates a degree of importance of the input image by position from the extracted feature amount in accordance with a predetermined regression model.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: April 28, 2020
    Assignee: RICOH COMPANY, LTD.
    Inventor: Takayuki Hara
  • Patent number: 10524735
    Abstract: This relates to methods for measuring irregularities in a signal and corresponding devices. The devices can include a PPG sensor unit configured to detect multiple occurrences of a given event in the measured signal(s) over a sampling interval. In some instances, the device can register the occurrences of the events. In some examples, the device can include one or more motion sensors configured to detect whether the device is in a low-motion state. The device may delay initiating measurements when the device is not in a low-motion state to enhance measurement accuracy. Examples of the disclosure further include resetting the sample procedure based on one or more factors such as the number of non-qualifying measurements. In some examples, the device can be configured to perform both primary and secondary measurements, where the primary measurements can include readings using a set of operating conditions different from the secondary measurements.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: January 7, 2020
    Assignee: Apple Inc.
    Inventors: Stephen J. Waydo, Christopher J. Brouse, Ian R. Shapiro, Joseph C. McBride, Michael O'Reilly, Myra Mary Haggerty
  • Patent number: 10463283
    Abstract: An exemplary system comprises an energy transmitter, an energy receiver, and an analyzer. The energy transmitter may project energy at a first wavelength and a second wavelength into tissue of a user, the first wavelength and the second wavelength being associated with at least one nutrient of a set of nutrients in blood of the user. The energy receiver may generate a composite signal based on a fraction of the energy at the first wavelength and the second wavelength, the fraction of the energy being received through the tissue of the user. The analyzer may separate the composite signal into a first signal corresponding to the first wavelength and a second signal corresponding to the second wavelength, and detect, in the blood of the user, a concentration of the at least one nutrient of the set of nutrients based on the first signal and the second signal.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: November 5, 2019
    Assignee: Spry Health, Inc.
    Inventors: Elad Ferber, Pierre-Jean Cobut
  • Patent number: 10441203
    Abstract: A space-saving structural component for a device, the device configured to non-invasively determine a tissue bioparameter of a mammalian subject, the component comprising a wall surface including a grooved recess and at least one shoulder; and a substantially flat cover, the cover configured to cover the wall surface by moving from an open position far enough away from the wall surface to allow insertion of an appendage of the subject into a chamber defined by the grooved recess and the cover, to a closed position, the cover comprising a flexible material that, in the closed position, elastically deforms away from the wall surface when the appendage is present in the grooved recess and restores to a substantially flat state when the appendage is absent from the grooved recess, wherein in the closed position, when the appendage is absent from the recess, the cover is adjacent the at least one shoulder.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: October 15, 2019
    Assignee: CNOGA MEDICAL LTD.
    Inventor: Yosef Segman
  • Patent number: 10426356
    Abstract: A method and system for communicating estimated blood loss parameters of a patient to a user, the method comprising: receiving data representative of an image, of a fluid receiver; automatically detecting a region within the image associated with a volume of fluid received at the fluid receiver, the volume of fluid including a blood component; calculating an estimated amount of the blood component present in the volume of fluid based upon a color parameter represented in the region, and determining a bias error associated with the estimated amount of the blood component; updating an analysis of an aggregate amount of the blood component and an aggregate bias error associated with blood loss of the patient, based upon the estimated amount of the blood component and the bias error; and providing information from the analysis of the aggregate amount of the blood component and the aggregate bias error, to the user.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: October 1, 2019
    Assignee: Gauss Surgical, Inc.
    Inventors: Siddarth Satish, Andrew T. Hosford, Kevin J. Miller, Milton McColl, Juan Carlos Aragon
  • Patent number: 10416094
    Abstract: A system for characterizing a dielectric object situated adjacent to an electrically conductive surface comprises a radiation source configured to radiate electromagnetic energy toward the dielectric object, and a receiver configured to receive scattered electromagnetic energy scattered by the dielectric object and the electrically conductive surface. The system may further comprise a control subsystem, coupled to the radiation source and the receiver, that determines an apparent focal point within the object, determines a phase shift associated with the scattered electromagnetic energy with respect to the electromagnetic energy radiated by the radiation source, and determine a thickness and an index of refraction of the object based, on the apparent focal point and the phase shift. The system may determine the apparent focal point by scanning a calculated focus point of the radiated energy through different depths of the object, and searching for a peak in an amplitude of the scattered energy.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: September 17, 2019
    Assignee: Northeastern University
    Inventors: Carey Rappaport, Jose A. Martinez-Lorenzo, Ann Morgenthaler
  • Patent number: 10352922
    Abstract: A system for measuring hematocrit in a whole blood sample is provided. An absorbent substrate is adapted to receive a whole blood sample. At least one light source is positioned to illuminate the sample on the substrate at first and second wavelengths. The first and second wavelengths are different from each other. A spectral sensor is positioned to measure a first intensity and a second intensity of light diffusely reflected from the sample at the first and second wavelengths, respectively. The diffusely reflected first and second intensities of light are compared to reference values to generate first and second reflectance values. A controller, coupled to the spectral sensor, is configured to determine a first differential reflectance between the first and second reflectances. The hematocrit level of the sample is determined based on a first stored relationship between hematocrit and a differential reflectance corresponding to the first and second wavelengths.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: July 16, 2019
    Assignee: THERMO FINNIGAN LLC
    Inventors: Steven L. Reeber, John Glazier
  • Patent number: 10321115
    Abstract: A three-dimensional (3D) depth sensor may include: a plurality of light sources configured to irradiate light to an object, the light having different center wavelengths; an optical shutter configured to allow reflected light reflected from the object to pass through; and an image sensor configured to filter the reflected light having passed through the optical shutter and detect the filtered light.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: June 11, 2019
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Weiming Li, Mingcai Zhou, Ya Lu, Chun Wang, Myungjae Jeon
  • Patent number: 10299724
    Abstract: A wristwatch includes a case containing electronic components of the wristwatch. An optoelectronic module including at least one light emitting element and at least one light sensing element is disposed within the case or within a fastener for the wristwatch. The optoelectronic module is operable to obtain physiological data of a person wearing the wristwatch by using the light emitting element and the light sensing element.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: May 28, 2019
    Assignee: ams Sensors Singapore Pte. Ltd.
    Inventor: Ohad Meitav
  • Patent number: 10282839
    Abstract: A variation of a method for estimating a quantity of a blood component in a fluid canister includes: within an image of a canister, identifying a reference marker on the canister; selecting an area of the image based on the reference marking; correlating a portion of the selected area with a fluid level within the canister; estimating a volume of fluid within the canister based on the fluid level; extracting a feature from the selected area; correlating the extracted featured with a concentration of a blood component within the canister; and estimating a quantity of the blood component within the canister based on the estimated volume and the concentration of the blood component within the canister.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: May 7, 2019
    Assignee: Gauss Surgical, Inc.
    Inventors: Siddarth Satish, Ali Zandifar, Kevin J. Miller
  • Patent number: 10258265
    Abstract: The present disclosure relates to noninvasive methods, devices, and systems for measuring various blood constituents or analytes, such as glucose. In an embodiment, a light source comprises LEDs and super-luminescent LEDs. The light source emits light at least wavelengths of about 1610 nm, about 1640 nm, and about 1665 nm. In an embodiment, the detector comprises a plurality of photodetectors arranged in a special geometry comprising one of a substantially linear substantially equal spaced geometry, a substantially linear substantially non-equal spaced geometry, and a substantially grid geometry.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: April 16, 2019
    Assignee: MASIMO CORPORATION
    Inventors: Jeroen Poeze, Marcelo Lamego, Sean Merritt, Cristiano Dalvi, Hung Vo, Johannes Bruinsma, Ferdyan Lesmana, Massi Joe E. Kiani, Greg Olsen
  • Patent number: 10247666
    Abstract: A detector has a sensor responsive to a first wavelength, a sensor responsive to a second wavelength, and a sensor for collecting reference readings. A gas sample is analyzed to obtain readings corresponding to the first wavelength, the second wavelength and a reference. A first absorption figure is calculated using the first reading and the reference reading, and a second absorption figure using the second reading and the reference reading. A linearizer function is applied to the first and second absorption figures to calculate first and second concentration figures. The sensor for each wavelength is calibrated for detecting the first gas such that the data collected at each wavelength gives the same reading when only the first gas is present. The ratio of the first concentration figure to the second concentration figure is used to identify whether only the first gas is present.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: April 2, 2019
    Assignee: Gas Measurement Instruments Limited
    Inventors: Crawford Massie, Fraser Mathieson, Andrew Glendinning
  • Patent number: 10241034
    Abstract: A concentration measurement method accurately, quickly, and non-destructively measures the concentration of a predetermined chemical component within an object to a nano-order trace concentration level in real time. A time sharing method irradiates the object light of a first wavelength and light of a second wavelength having different light absorption rates with respect to the object to be measured. Light of both wavelengths that arrives optically through the object is received by a shared light reception sensor, and signals respectively relating to light of the first and second wavelengths are output from the light reception sensor in accordance with the received light. A differential signal of these signals is formed, and the concentration of a chemical component in the object to be measured is derived on the basis of the differential signal.
    Type: Grant
    Filed: August 24, 2015
    Date of Patent: March 26, 2019
    Assignee: TOHOKU UNIVERSITY
    Inventors: Shigetoshi Sugawa, Rihito Kuroda
  • Patent number: 10231670
    Abstract: Systems and methods are disclosed for proximity sensing in physiological sensors, and more specifically to using one or more proximity sensors located on or within a physiological sensor to determine the positioning of the physiological sensor on a patient measurement site. Accurate placement of a physiological sensor on the patient measurement site is a key factor in obtaining reliable measurement of physiological parameters of the patient. Proper alignment between a measurement site and a sensor optical assembly provides more accurate physiological measurement data. This alignment can be determined based on data from a proximity sensor or sensors placed on or within the physiological sensor.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: March 19, 2019
    Assignee: MASIMO CORPORATION
    Inventors: Thomas B. Blank, Gregory A. Olsen, Cristiano Dalvi, Hung T. Vo
  • Patent number: 10219746
    Abstract: An embodiment of the present disclosure seeks to select characteristics of incoming intensity data that cause comparisons of selected characteristics to produce defined probe off space having reduced crossover with defined probe on space. Once defined, the present disclosure compares characteristics of incoming intensity data with the now defined probe off space, and in some embodiments, defined probe on space, to determine whether a probe off condition exists. When a processor determines a probe off condition exists, the processor may output or trigger an output signal that audibly and/or visually indicates to a user that the optical sensor should be adjusted for a proper application to a measurement site.
    Type: Grant
    Filed: June 20, 2016
    Date of Patent: March 5, 2019
    Assignee: Masimo Corporation
    Inventors: Ryan Timothy McHale, Walter M. Weber
  • Patent number: 10132792
    Abstract: Disclosed herein are portable diagnostic measurement devices for determining at least one analysis parameter of a bodily fluid, in particular for determining an analyte concentration in a bodily fluid as can occur in blood glucose determinations. Also disclosed are analysis systems including the measurement device and at least one disposable test element. The test element can be designed as a carrier strip and can contact a receiving surface of the measurement device at least partially in a flat manner, where the receiving surface is arranged on a narrow side of the housing of the measurement device.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: November 20, 2018
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Heino Eikmeier, Hans-Peter Haar, Joachim Hoenes, Carina Horn, Ewald Rieger
  • Patent number: 10085679
    Abstract: A system and method for detecting vascular contamination by surgical anesthetic using non-invasive IR spectrophotometry. One embodiment is a method for operating an instrument such as an enhanced pulse oximeter to monitor a patient receiving local anesthetic marked with dye that absorbs infrared light. Light is applied to and detected from tissue of the patient. A signal representative of the detected light is processed to derive patient oxygenation information. The detected light is also processed to derive information representative of the presence of the dye-marked anesthetic. The oxygenation information and the information representative of the presence of anesthetic are displayed. The oxygenation monitoring and display and the anesthetic monitoring and display can occur separately or concurrently. Fluorescing dyes and fluorescence detection approaches are used for anesthetic detection in some embodiments.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: October 2, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Steven R. Clendenen, Clifton R. Haider, Barry K. Gilbert, Oliver William Spees
  • Patent number: 10048114
    Abstract: In a device for measuring the vibrational amplitude of a capillary tube of a wire bonder, the capillary tube is placed between a light source and a detector system, so that the vibrational amplitude is able to be ascertained from the shading of a beam of light by the capillary tube. The beam of light emitted by the light source is split into a measuring beam of light and a reference beam of light, an edge of the capillary tube at least partially shading the measuring beam of light in the vibrating state, while the reference beam of light is not shaded. The detector system includes a measuring detector assigned to the measuring beam of light as well as at least one reference detector assigned to the reference beam of light, and the vibrational amplitude of the capillary tube is ascertainable from the interconnected output signals of the measuring detector and the reference detector.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: August 14, 2018
    Assignee: DR. JOHANNES HEIDENHAIN GMBH
    Inventors: Walter Huber, Wolfgang Holzapfel
  • Patent number: 10039491
    Abstract: Optical measurement of physiological parameters with wearable devices often includes measuring signals in the presence of significant noise sources. These noise sources include, but are not limited to, noise associated with: variable optical coupling to skin or tissue, variations in tissue optical properties with time due to changes in humidity, temperature, hydration, variations in tissue optical properties between individuals, variable coupling of ambient light sources into detectors, and instrument and detector noise, including electrical noise, radio frequency or magnetic interference, or noise caused by mechanical movement of the detector or its components. The present disclosure includes devices and methods configured to produce representations of the raw data in which noise, broadly defined, is separated from the data of interest. The disclosed devices and methods may include subtracting or calibrating out these noise sources and other spurious fluctuations in wearable devices with optical sensors.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: August 7, 2018
    Assignee: Verily Life Sciences LLC
    Inventors: Jason Donald Thompson, Vikram Singh Bajaj, Victor Marcel Acosta, Tamara Lynn Troy
  • Patent number: 10022089
    Abstract: The invention relates to a device and a method for noninvasive measurement of parameters of a bodily tissue, the measuring device having a sensor unit and a sensor mat for detachable placement of the device on a body surface. The sensor unit (1) has a receptacle (6), the interior of which accommodates a sensor arrangement, wherein the receptacle (6) has a sensor surface (15) in the direction of the body surface. The sensor mat (8) has a cutout (11) for accommodating the sensor unit (1) and a contact surface (14), at least partially surrounding the sensor unit (1), for placement on the body surface (9). A cover (12) is provided for closing the cutout (11) over an upper side of the sensor unit (1) and the sensor mat (8) during a measurement of parameters. The sensor unit (1), the sensor mat (8) and the cover (12) are detachable from one another.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: July 17, 2018
    Assignee: Luciole Medical AG
    Inventors: Christophe Lechot, Jean-Claude Frely, Marcel Aeschlimann, Juerg Hans Froehlich, Dirk Baumann, Markus Hugo Muser, Michael Oberle
  • Patent number: 10004410
    Abstract: The present invention relates generally to a system and methods for measuring physiological parameters. More specifically, the present invention relates to a noncontact technology by which one or more physiological parameters of a subject may be efficiently and quickly detected. Among other advantages, the present invention can be used to assess and monitor vital signs of one or more subjects in a variety of contexts including for medical or security triage purposes, for use in healthcare waiting rooms, as part of human imaging systems, or during surgery.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: June 26, 2018
    Assignees: The Board of Trustees of the University of Illinois, The University of North Carolina at Chapel Hill
    Inventors: Stephen W. Porges, Maria I. Davila, Gregory F. Lewis
  • Patent number: 9996758
    Abstract: A biometric sensor apparatus for capturing patterns of blood vessels on the inner side of a wrist. The sensor apparatus has a strap with a near infrared camera mounted on a part of the strap. The camera is arranged for capturing an image of the blood vessels when it is temporarily held at an increased distance from the wrist than when the apparatus is simply being worn by the user. In some embodiments the camera is held at the required position for capturing the images of the blood vessels when the wrist strap is being opened or closed. In some embodiments the camera may be mounted in a deployant clasp of the wrist strap.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: June 12, 2018
    Assignee: Biowatch SA
    Inventors: Joseph Rice, Matthias Vanoni
  • Patent number: 9976989
    Abstract: A monitoring system includes an acoustic emission monitoring system including acoustic emission sensors, a partial discharge monitoring system including partial discharge sensors and synchronized with the acoustic emission monitoring system, and a computer receiving acoustic emission data from the acoustic emission sensors and electrical data from the partial discharge sensors. The computer is configured to classify a first statistical event as a fatigue cracking event by pattern recognition of the acoustic emission data and determine a first location and a first damage condition resulting from the fatigue cracking event, classify a second statistical event as a partial discharge event by pattern recognition of the acoustic emission data or the electrical data, and fuse the acoustic emission data and the electrical data for the second statistical event and determine a second location and a second damage condition resulting from the partial discharge event. Methods of monitoring are also disclosed.
    Type: Grant
    Filed: December 15, 2015
    Date of Patent: May 22, 2018
    Assignee: General Electric Company
    Inventors: Ehsan Dehghan Niri, Curtis Wayne Rose, Andrew Batton Witney
  • Patent number: 9943240
    Abstract: A non-invasive method for determining the tissue perfusion state in a patient, by measuring the variations in the skin CO2 pressure and in the perfusion index of the patient during the conducting of a localized hyperthermia test.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: April 17, 2018
    Assignee: Assistance Publique—Hopitaux de Paris
    Inventors: Fabrice Vallee, Joaquim Mateo, Didier Payen De La Garanderie
  • Patent number: 9936905
    Abstract: A device for detection or measurement of a carbohydrate analyte in fluid comprises: an optical sensor comprising components of an assay for carbohydrate analyte, the readout of which is a detectable or measurable optical signal, and a light guide having a distal portion optically coupled to the assay components and a proximal portion; and a reader for interrogating the optical sensor, the reader comprising an assay interrogating system including a lens; and an interface portion forming part of at least one of the optical sensor and the reader, the interface portion being capable of removably constraining the proximal portion of the light guide and the lens of the assay interrogating system in an optically coupled arrangement. The device may be combined with an insulin-infusion system.
    Type: Grant
    Filed: October 13, 2014
    Date of Patent: April 10, 2018
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Eric Allan Larson, Voltaire Isaac Lebron, Kevin Holz, Jasson Rodriguez, Ameya Kantak, Soren Aasmul
  • Patent number: 9883808
    Abstract: Provided are a photo-acoustic imaging apparatus and a method of displaying a photo-acoustic image by the photo-acoustic imaging apparatus. The method of displaying a photo-acoustic image by a photo-acoustic imaging apparatus includes: obtaining a first reception signal, which converts a first acoustic wave generated as light having a first wavelength is absorbed by a subject, and a second reception signal, which converts a second acoustic wave generated as light having a second wavelength is absorbed by the subject; determining a first correction coefficient for the first reception signal and a second correction coefficient for the second reception signal based on a ratio between a size of the first reception signal and that of the second reception signal; and displaying a photo-acoustic image which is corrected based on the first and second correction coefficients.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: February 6, 2018
    Assignee: SAMSUNG MEDISON CO., LTD.
    Inventors: Dal-Kwon Koh, Jung-Taek Oh, Jung-Ho Kim, Jong-Kyu Jung
  • Patent number: 9877686
    Abstract: This disclosure describes, among other features, systems and methods for using multiple physiological parameter inputs to determine multiparameter confidence in respiratory rate measurements. For example, a patient monitoring system can programmatically determine multiparameter confidence in respiratory rate measurements obtained from an acoustic sensor based at least partly on inputs obtained from other non-acoustic sensors or monitors. The patient monitoring system can output a multiparameter confidence indication reflective of the programmatically-determined multiparameter confidence. The multiparameter confidence indication can assist a clinician in determining whether or how to treat a patient based on the patient's respiratory rate.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: January 30, 2018
    Assignee: MASIMO CORPORATION
    Inventors: Ammar Al-Ali, Bilal Muhsin, Michael O'Reilly
  • Patent number: 9870625
    Abstract: A method and system for communicating estimated blood loss parameters of a patient to a user, the method comprising: receiving data representative of an image, of a fluid receiver; automatically detecting a region within the image associated with a volume of fluid received at the fluid receiver, the volume of fluid including a blood component; calculating an estimated amount of the blood component present in the volume of fluid based upon a color parameter represented in the region, and determining a bias error associated with the estimated amount of the blood component; updating an analysis of an aggregate amount of the blood component and an aggregate bias error associated with blood loss of the patient, based upon the estimated amount of the blood component and the bias error; and providing information from the analysis of the aggregate amount of the blood component and the aggregate bias error, to the user.
    Type: Grant
    Filed: April 15, 2015
    Date of Patent: January 16, 2018
    Assignee: Gauss Surgical, Inc.
    Inventors: Siddarth Satish, Andrew T. Hosford, Kevin J. Miller, Milton McColl, Juan Carlos Aragon
  • Patent number: 9861305
    Abstract: A method and an apparatus for separating a composite signal into a plurality of signals is described. A signal processor receives a composite signal and separates a composite signal into separate output signals. Feedback from one or more of the output signals is provided to a configuration module that configures the signal processor to improve a quality of the output signals. In one embodiment, calibration data from multiple calibration data sets is used to configure the demodulation of the composite signal into separate output signals.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: January 9, 2018
    Assignee: Masimo Corporation
    Inventors: Walter M. Weber, Ammar Al-Ali, Mohamed K. Diab, Marcelo M. Lamego
  • Patent number: 9833179
    Abstract: A blood component is accurately analyzed by appropriately extracting a blood-vessel transmitted light component. In a blood component analyzing apparatus, a sensor section has a light-emitting section that irradiates light from a predetermined irradiation position situated over a blood vessel and a light-receiving section including a first photodetector that receives light at a first light-receiving position that is different from the irradiation position and is situated over the blood vessel and a second photodetector that receives light at a second light-receiving position that is not situated over the blood vessel. A spectrum synthesizing section synthesizes a first light-reception result at the first light-receiving position and a second light-reception result at the second light-receiving position by performing a predetermined synthesis process based on a positional relationship among the irradiation position, first light-receiving position, and second light-receiving position.
    Type: Grant
    Filed: December 24, 2014
    Date of Patent: December 5, 2017
    Assignee: Seiko Epson Corporation
    Inventor: Akira Ikeda
  • Patent number: 9808188
    Abstract: The present disclosure describes the derivation and measurement of a fractional oxygen saturation measurement.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: November 7, 2017
    Assignee: MASIMO CORPORATION
    Inventors: Philip Perea, Ammar Al-Ali, Massi Joe E. Kiani
  • Patent number: 9808197
    Abstract: According to one embodiment, a wearable electronic apparatus detects movement of a human body wearing the apparatus. The apparatus causes a first number of light emitters to emit light when a magnitude of the detected movement is less than a first value. The first number of light emitters is among a plurality of light emitters which emit light having different wavelengths, in which the light are received by a light receiver to obtain physiological information. The apparatus causes a second number greater than the first number of light emitters among the plurality of light emitters to emit light when the magnitude of the detected movement is greater than or equal to the first value.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: November 7, 2017
    Assignee: Kabushiki Kaisha Toshiba
    Inventors: Takaya Matsuno, Takashi Sudo, Yasuhiro Kanishima
  • Patent number: 9788787
    Abstract: The present invention is a Miniature Vein Enhancer that includes a Miniature Projection Head. The Miniature Projection Head may be operated in one of three modes, AFM, DBM, and RTM. The Miniature Projection Head of the present invention projects an image of the veins of a patient, which aids the practitioner in pinpointing a vein for an intravenous drip, blood test, and the like. The Miniature projection head may have a cavity for a power source or it may have a power source located in a body portion of the Miniature Vein Enhancer. The Miniature Vein Enhancer may be attached to one of several improved needle protectors, or the Miniature Vein Enhancer may be attached to a body similar to a flashlight for hand held use. The Miniature Vein Enhancer of the present invention may also be attached to a magnifying glass, a flat panel display, and the like.
    Type: Grant
    Filed: May 6, 2015
    Date of Patent: October 17, 2017
    Assignee: AccuVein, Inc.
    Inventors: Ron Goldman, David Hunt, Mark Mock, Graham Marshall, Stephen P Conlon, Robert Roth
  • Patent number: 9743881
    Abstract: Functional imaging for localization in biological tissue entails measuring a response in the tissue (240) to electromagnetic radiation. A catheter (200) for real-time monitoring of cardiac ablation is employed to distinguish a hemorrhage zone (232) from the sandwiching necrotic and healthy tissue, or to distinguish exogenous photoacoustic contrast agent from bordering native tissue. A pair of wavelengths is selected for differential absorption (244) of the radiation in, correspondingly, the hemorrhage zone or where the contrast agent exists, and relatively similar absorption elsewhere. Near infrared laser or LED light may be used photoacoustically to serially acquire (S310, S320) the two datasets to be compared, each representative of a time waveform. Alternatively, acquisition is for a pair of wavelength bands of microwave-induced thermoacoustic data.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: August 29, 2017
    Assignee: Koninklijke Philips N.V.
    Inventors: Emil Radulescu, Sheng-Wen Huang, Ramon Erkamp, Ladislav Jankovic, Yan Shi, Khalid Shahzad
  • Patent number: 9734304
    Abstract: Apparatuses and methods are disclosed for identifying with a single, small, intelligent activity monitor a particular type of activity from among a plurality of different activities. The monitor may include a multi-axis accelerometer and microcontroller configured to combine and process accelerometer data so as to generate features representative of an activity. The features may be processed to identify a particular activity (e.g., running, biking, swimming) from among a plurality of different activities that may include activities not performed by a human subject. An intelligent activity monitor may be configured to operate as a versatile sensor, or to operate in combination with a versatile sensor, to further receive and process physiological data and compute a fitness metric for a subject.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 15, 2017
    Assignee: LUMIRADX UK LTD
    Inventors: Thomas P. Blackadar, David P. Monahan
  • Patent number: 9668703
    Abstract: A patient monitor for displaying a physiological signal can include a visual element having a middle portion indicative of a transition in the physiological signal between physiological states. The visual element can also include first and second extremity portions, the first extremity portion extending from the middle portion in a first direction and the second extremity portion extending from the middle portion in a second direction. The visual element can also include an actionable value indicator to specify a value about the middle portion and the first and second extremity portions. The patient monitor can also include a processor configured to cause the value indicator to actuate in both the first and second directions according to changes in the physiological signal.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: June 6, 2017
    Assignee: Masimo Corporation
    Inventor: Ammar Al-Ali
  • Patent number: 9668682
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: June 6, 2017
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Jack Pryor, John Nolting, Jacob S. Leach, Luis Pestana, Nelson Quintana, Vance Swanson, Paul V. Goode, Jr., James Patrick Thrower
  • Patent number: 9642538
    Abstract: A health care band operably attaches a biosensor to a patient. The biosensor includes one or more sensors for collecting vitals of a patient and a wireless transmitter that is configured to communicate with an EMR network that stores and maintains an EMR of the patient. The biosensor stores a unique identification associated with the patient's EMR such that vitals measured by the biosensor may be transmitted with the patient's unique identification for storage in the patient's EMR. The sensors in the biosensor may include a thermometer, motion detector/accelerometer, pulse detector and oximeter, etc. In an embodiment, one of the sensors in the biosensor includes a photoplethysmography (PPG) based sensor that may be configured to continuously or periodically measure a patient's vitals, such as heart rate, pulse, blood oxygen levels, blood glucose or insulin levels, or other blood analytics in vitro.
    Type: Grant
    Filed: September 25, 2016
    Date of Patent: May 9, 2017
    Assignee: Sanmina Corporation
    Inventor: Robert Steven Newberry
  • Patent number: 9603561
    Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.
    Type: Grant
    Filed: April 24, 2014
    Date of Patent: March 28, 2017
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Andrea Varsavsky, Xiaolong Li, Mike C. Liu, Yuxiang Zhong, Ning Yang
  • Patent number: 9591975
    Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: March 14, 2017
    Assignee: MASIMO CORPORATION
    Inventors: Cristiano Dalvi, Marcelo Lamego, Sean Merritt, Hung Vo, Johannes Bruinsma, Jeroen Poeze, Ferdyan Lesmana, Greg Olsen, Massi Joe E. Kiani
  • Patent number: 9594020
    Abstract: Blood separation systems and methods are provided for controlling the interface between separated blood components. The system includes a centrifuge assembly having a light-transmissive portion, a light reflector, and a fluid processing region therebetween. An optical sensor system emits a scanning light beam along a path toward the light-transmissive portion, which transmits at least a portion of the scanning light beam to the fluid processing region and the light reflector. The light reflector reflects at least a portion of the scanning light beam toward the optical sensor system along a path substantially coaxial to the path of the scanning light beam from the optical sensor system toward the light-transmissive portion of the centrifuge assembly. The scanning light beam may be a white light beam or narrow spectrum beam. The reflected beam may be directed through the optical sensor system via optical fibers.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 14, 2017
    Assignee: Fenwal, Inc.
    Inventors: Peter David Koudelka, Ryan Eliot Eckman, Eric Karl Lindmark, Lubomir Koudelka, James Joseph Ulmes, Steven R. Katz, William H. Cork
  • Patent number: 9572534
    Abstract: Devices, systems, methods and kits for releasably mounting a medical device on the body or skin of a user are provided.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: February 21, 2017
    Assignee: ABBOTT DIABETES CARE INC.
    Inventor: Gary Ashley Stafford
  • Patent number: 9566027
    Abstract: A medical device is presented for reduced-pain blood sampling and testing. The device comprises a housing defining a finger site for supporting a user's finger or a portion thereof within said finger site during the device operation; piercing, sampling and testing assemblies sequentially actuatable to successively initiate piercing, sampling and testing operational modes of the device; a carriage at least partially accommodated within said housing and being adapted for movement with respect to said finger site between its first position corresponding to the piercing mode of the device and a second position corresponding to the sampling and testing modes of the device, the device being thereby capable of operating in the piercing, sampling and testing modes while at a static position of the user's finger.
    Type: Grant
    Filed: June 23, 2011
    Date of Patent: February 14, 2017
    Assignee: RAPIDX LTD.
    Inventor: Nili Tamir