Abstract: Apparatus, methods, and other embodiments associated with objectively predicting biochemical recurrence with co-occurring gland tensors in localized subgraphs are described. One example apparatus includes a set of logics that associate directional disorder with a risk of failure in a material. A first logic detects a fundamental unit of composition in the material, segments boundaries of the fundamental unit, and calculates a directional tensor for the fundamental unit. A second logic constructs a localized sparsified subgraph whose nodes represent centroids of the fundamental units, defines pairwise spatial relationships between the fundamental units, and constructs a directional co-occurrence matrix based on the spatial relationships. A third logic derives second order statistical features from the co-occurrence matrix, and produces a risk failure score as a function of the second order statistical features.

Abstract: The present disclosure provides various methods and systems for performing magnetic resonance studies. In accordance with many embodiments, image or other information of interest is derived from super radiant pulses.

Abstract: Method and system embodiments of the present invention employ computational analysis tools running on one or more computer systems to quantitatively analyze MRI data from patients in order to both assess various functional parameters and characteristics of a patient's kidney, as well as to provide an electronic display device interconnected with the one or more computer systems, and accessible visualization of the quantitative assessment to facilitate diagnosis of various types of kidney abnormalities and pathologies.

Abstract: A system and method for acquiring an image of a region of interest (ROI) of subject using a computed tomography (CT) system includes a) performing a scout scan of the subject using the CT system to yield scout data related to the ROI and b) determining an initial contrast volume form at least the scout data. The method also includes c) prescribing a scanning protocol to be implemented using the computed tomography system to image the ROI and d) determining a size of the subject about the ROI. The method further includes e) determining a computed tomography dose related to volume (CTDIvol) based on at least the size determined at step d) and f) adjusting the scanning protocol prescribed in step b) to match at least one of a desired radiation dose and a relative intravenous (IV) contrast dose to a reference CTDIvol. The method includes g) acquiring imaging data from the ROI using the CT system by using the adjusted scanning protocol.

Abstract: A magnetic resonance imaging apparatus according to embodiments includes an executing unit, an informing unit, a detecting unit, and a determining unit. The executing unit executes a pulse sequence to collect data of a subject at a constant cycle. The informing unit informs the subject of a timing of breathing in synchronization with the cycle at which the pulse sequence is executed. The detecting unit detects a breathing level or a respiratory cycle of the subject. The determining unit determines, when the pulse sequence is executed, whether to use the data collected by the pulse sequence for image reconstruction in accordance with the breathing level or the respiratory cycle of the subject.

Abstract: A magnetic resonance imaging (MRT) method for jointly estimating an image degradation and reconstructing an image of a subject in which that image degradation is mitigated is provided. The MRI system is operated to acquire multiple different k-space data sets that are acquired with different acquisition parameters so as to modulate the image degradation to be estimated. Using an iterative process, the image degradation is estimated while jointly reconstructing an image in which the estimated image degradation is mitigated.

Abstract: A computer-implemented method for concurrently estimating the amount of fat and iron in anatomical tissue from magnetic resonance (MR) signal data includes receiving a test signal representative of the anatomical tissue acquired using a MR pulse sequence type. A repository of reference signal data is generated. The repository comprises a plurality of reference signals derived by an MR signal simulation for a plurality of different transverse relaxation rates, a plurality of different fat fractions, and the MR pulse sequence type. A first reference signal is identified in the plurality of reference signals. The first reference signal provides a best match to the test signal based on one or more matching criteria. The repository is searched to determine a first transverse relaxation rate and a first fat fraction associated with the first reference signal. Then, the amount of fat and iron in the anatomical tissue is estimated based on the first transverse relaxation rate and the first fat fraction.

Abstract: A method, a software program and a system for processing MRT data of the human brain of a patient, wherein three-dimensional MRT data resolved in voxels of the patient's brain and the brains of a normative database of a plurality of neurologically healthy human individuals are available. The MRT data of the patient's brain are segmented for each voxel into portions of grey substance, white substance and liquor by means of a classification algorithm, wherein for comparison with corresponding data of the normative database the data are normalized before, after or synchronously into a standardized stereotactic space whereby one or more normalized tissue maps result that contain the proportions determined by the classification algorithm, and the tissue map or tissue maps of the patient's brain is or are subjected to a voxel-wise statistical comparison with the correspondingly normalized and segmented data of the normative database.

Abstract: A magnetic resonance imaging apparatus according to an exemplary embodiment includes a first imaging unit, an identifying unit, and a second imaging execution unit. The first imaging execution unit acquires, after applying a labeling RF pulse to blood flowing into the myocardium of a subject, multiple non-contrast MR data for which the time intervals between labeling and acquiring data are different by performing sequential imaging of an imaging area including the myocardium in each segment of a k-space for a given time interval. The identifying unit identifies a time interval taken by the labeled blood to reach a given position in the imaging area. The second imaging execution unit sets the identified time interval and, after applying a labeling RF pulse to the blood flowing into the myocardium of the subject, acquires non-contrast MR data by imaging the imaging area including the myocardium.

Abstract: A method for content-based image retrieval for the classification of breast density from mammographic imagery is described. The breast density is characterized through the Fisher linear discriminants (FLD) extracted from the Principal Component Analysis (PCA). Unlike PCA, the FLD provides a very discriminative representation of the mammographic images in terms of the breast density. Various exemplary methods, systems and computer program products are also disclosed.

Abstract: In one aspect of the disclosure, an MRI-based system includes an MRI scanner having a first axis and a first plane perpendicular to the first axis, a pulse sequence module configured to provide a 3D pulse sequence to the MRI scanner, and a control module configured to instruct the MRI scanner to conduct radial k-space samples having N second planes that each are perpendicular to the first plane and through which the first axis passes, N being an integer greater than 1. The 3D pulse sequence instructs the MRI scanner to a radio-frequency (RF) pulse, conduct a gradient readout in the first plane, and conduct a gradient readout in one of the N second planes.

Abstract: Apparatus for radiation therapy combines a patient table, an MRI and a radiation treatment apparatus mounted in a common treatment room with the MR magnet movable from a position outside a radiation shielded door to an imaging position. An RF-shielded door is movable between a position, separating part of the treatment apparatus from the magnet and an open position allowing access of the patient to the treatment apparatus. In one configuration there is a row of treatment rooms and the magnet is mounted to move along a passageway outside the row of radiation shielded doors of the rooms.

Abstract: An image processing device includes a memory; and a processor coupled to the memory and configured to: acquire, for each of different entrance positions, each of captured images generated by changing the luminance of pixels within a given distance from an entrance position indicating a location at which light is incident to a photographic subject, the pixels being in an image obtained by illuminating the photographic subject with the light from a light source and capturing the light reflected from the photographic subject, generate a composite image by adding together each of the captured images, and generate an output image by performing image restoration on the composite image by using a model having the shape of the reflected light.

Abstract: A microwave ablation device including a cable assembly configured to connect a microwave ablation device to an energy source and a feedline in electrical communication with the cable assembly. The microwave ablation device further includes a balun on an outer conductor of the feedline, and a temperature sensor on the balun sensing the temperature of the balun.

Abstract: Systems and methods for control of a medical data processing system are provided. Some embodiments are particularly directed to presenting a user interface for control of an IVUS imaging system. In one embodiment, a method comprises: presenting a set of mode options to a user at a user display device; receiving a mode selection selected by the user; determining a set of operating parameters based on the mode selection; receiving, by a medical processing system, a first set of medical sensing data; and processing, by the medical processing system, the first set of medical sensing data according to the operating parameters. The determining may be further based on at least one of a previous mode selection, a user preference, an operative course of a medical procedure, patient information, the first set of medical sensing data, a second set of medical sensing data, a status indicator, and a sensing device identifier.

Abstract: A system and method for producing an image of a vasculature of a subject using a magnetic resonance imaging (MRI) system includes applying a saturation pulse to a prescribed imaging slice to substantially suppress MR signals in the prescribed imaging slice. A quiescent inflow time period (QITP) is observed that is at least equal to half a projected duration of a cardiac cycle of the subject. After the QITP, k-space data is acquired from the prescribed imaging slice, and a subset of the data representative of a desired portion of the cardiac cycle of the subject is reconstructed into an image of the subject including at least the prescribed imaging slice.

Abstract: The present invention relates to an examination apparatus for providing information about an object and a method for providing information about an object of interest. In order to improve the visual reception of information relating to the object, an examination apparatus is provided that comprises an examination arrangement and a control unit with at least a first interface and a second interface. The examination arrangement is adapted to detect object data from at least one region of interest of an object and to provide the object data to the control unit. Further, the control unit is adapted to compute object data into object information and to transform at least a part of the object information into image data (32, 36). Further, the control unit is arranged to extract pre-determined indicative data from the object information and to transform the indicative data into graphical advisory data (40).

Abstract: A medical imaging processing method includes: using an imaging method to acquire at least first and second data sets of a region of interest of a patient's body, with at least one image acquisition parameter being changed so that first and second data sets yield different contrast levels relating to different substance and/or tissue types, and wherein the at least one acquisition parameter used to obtain the first data set is selected to enhance the contrast between one of the substance and/or tissue types relative to other substance and/or tissue types, and the at least one acquisition parameter used to obtain the second data set is selected to enhance the contrast between a different one of the substance and/or tissue types relative other substance and/or tissue types, thereby to optimize the contrast between at least three different substance and/or tissue types; and processing the two data sets to identify the different tissue types and/or boundaries therebetween.

Abstract: In a magnetic resonance method and system for automatic generation of a selective MR image from a first MR image (corresponding to raw data acquired at a first echo time after excitation pulses) and a second MR image (corresponding to raw data acquired at a second echo time after the same excitation pulses), wherein at least one raw data measurement point was measured in the absence of gradient fields, a time constant prevailing in the depicted imaging space is calculated from the measurement data measured during readout of the raw data measurement point measured in the absence of gradient fields. Weighting factors for the first and/or the second MR image are determined depending on this time constant. The selective MR image is generated by weighting the first and/or second MR image with the calculated weighting factors and subtraction of the weighted MR images from one another.

Abstract: A method of estimating an organ deformation model includes generating at least one 3D organ shape model of an organ of a subject based on at least one non-real time medical image representing a deformation state of the organ of the subject; generating a deformation space for the organ of the subject based on the at least one 3D organ shape model and prior knowledge regarding the organ; and estimating a 3D organ deformation model of the organ of the subject based on a real-time medical image of the organ of the subject and the deformation space.

Abstract: A medical instrument that comprises: a first-stage optic responsive to a tissue surface of a patient; a spectral separator optically responsive to the first stage optic and having a control input; an imaging sensor optically responsive to the spectral separator and having an image data output; and a diagnostic processor having an image acquisition interface with an input responsive to the imaging sensor and a filter control interface having a control output provided to the control input of the spectral separator.

Abstract: An image in which an area of interest on an image is optimally susceptibility-emphasized is obtained in susceptibility-emphasized imaging. A measuring order of plural echo signals is controlled in accordance with the size of a desired area of interest of an examinee. Preferably, a target frequency in a K space is determined in accordance with the size of the area of interest, and the measuring order of plural echo signals is controlled so that an echo signal corresponding to the target frequency is measured at a target echo signal or in the neighborhood of the target echo time.

Abstract: Exemplary embodiments of the present disclosure are directed to estimating an electrical property of tissue using MR images. Complex values having real components and imaginary components are generated and are associated with pixels in one or more MR images that corresponding to a region of tissue for which the electrical property is constant. An estimated value of the electrical property for the region of tissue is determined based on a least squared error estimation applied to the complex values.

Abstract: Example systems, apparatus, circuits, and so on described herein concern intervention-independent scan plane control for an MRI system. A tracking device capable of being manipulated independently of an interventional device in use to treat a patient transmits position signals describing an orientation of the tracking device to an MRI system. The MRI system determines a desired scan plan that will correspond to the orientation of the tracking device and performs a diagnostic scan on the desired scan plan.

Abstract: A voxel-based technique is provided for performing quantitative imaging and analysis of tissue image data. Serial image data is collected for tissue of interest at different states of the issue. The collected image data may be normalized, after which the registered image data is analyzed on a voxel-by-voxel basis, thereby retaining spatial information for the analysis. Various thresholds are applied to the registered tissue data to predict or determine the evolution of a disease state, such as brain cancer, for example.

Abstract: Means and methods for improving the MRI “image quality in an MRI imaging” apparatus comprising a non-superconducting electromagnet and a plurality of pole pieces are provided. Said means for improving the image quality chosen from the group consisting of (a) means for reducing degradation of MRI image quality due to B0 field instability; (b) means for decreasing or otherwise correcting residual magnetization; (c) means for providing a 3D scout image; and (d) any combination of the above. These means for improving the image quality provides greater resolution of the imaged object relative to an MRI apparatus not containing such means for improving image quality.

Abstract: This invention relates to methods for ascertaining at least one of liver fibrosis or cirrhosis in a subject, by processing of one or more medical images of the liver, using a computing machine, to quantify nodularity of the surface of the liver and calculate a liver surface nodularity score.

Abstract: A method for producing magnetic resonance images of a subject in which artifacts resulting from a localized source, such as from pulsatile blood flow, are substantially mitigated is provided. The location of an artifact source, at which spins corresponding to flowing blood are located, is identified. Using this identified artifact source location, a region-of-saturation is calculated. A magnetic resonance imaging (MRI) system is then directed to perform a pulse sequence that results in the generation of a radio frequency (RF) saturation field being produced by an array of RF transmission coils. The RF saturation field is sized and shaped according to the calculated region-of-saturation. Images are reconstructed from image data acquired after application of the RF saturation field, and artifacts related to motion of the spins at the identified location of the artifact source are substantially mitigated in these images.

Abstract: Systems and methods for processing magnetic resonance imaging (MRI) data are provided. A method includes receiving MRI data comprising a plurality of k-space points and deriving a plurality of image data sets based on the MRI data, each of the plurality of MRI image sets obtained by zeroing a different one of the plurality of k-space points. The method further includes computing image space metric values for each of the plurality of image data sets and adjusting a portion of the MRI data associated with ones of the image space metric values that fail to meet a threshold value to yield adjusted MRI data.

Abstract: An imaging system uses sensors to traverse an external portion of an object to generate a three dimensional image of the object.

Abstract: An incubator's closure assembly adapted to shut the aperture of a magnetic resonance imaging device (MRD) having an open bore extended along the MRD's longitudinal axis with a distal end and proximal end, the bore is terminated by the aperture located in the proximal end, into which a neonate's incubator is inserted, thereby shutting the MRD bore aperture. The closure assembly comprising at least one U-shaped conduit having (i) an array of distal and proximal sealing walls, both are substantially perpendicular to the longitudinal axis and having upwards and downwards directions, and (ii) a recess in between the walls having length, in upwards to downwards direction, and width, in distal to proximal direction, each of the proximal wall and the distal wall comprising a cutout at opposite directions, and wherein in the recess, the ratio of length to width is greater than a predefined value n.

Abstract: Discussed herein is an image processing device and a corresponding method for assessing inflammatory bowel diseases. A plurality of dynamic MRI sequence of images of a bowel that include peristalsis information of the bowel and static MRI image(s) of the bowel that identify at areas of inflammation, stenosis, and increased mural thickness of the bowel are processed. A displacement of the bowel caused by respiration of the patient is conducted on the dynamic MRI sequences by performing a non-rigid registration. A peristaltic activity is determined by performing motion flow analysis on the dynamic sequences of images. A peristaltic activity of the static MRI image(s) based on a weighted sum of two closest dynamic MRI sequences of images is computed and the static image is combined with the closest dynamic MRI sequence of images by performing a multi-modal registration.

Abstract: Tracking based on the gradient fields of magnetic resonance imaging (MRI) scanners based on passive operation of the tracking system without any change of the scanner's hardware or mode of operation. To achieve better tracking performance, a technique to create a custom MRI pulse sequence is disclosed. Through this technique any standard pulse sequence of the scanner can be modified to include gradient activations specifically designated for tracking. These tracking gradient activations are added in a way that does not affect the image quality of the native sequence. The scan time may remain the same as with the native sequence or longer due to the additional gradient activations. The tracking system itself can use all the gradient activations (gradient activations for imaging and gradient activations for tracking) or eliminate some of the gradients and lock onto the specific gradient activations that are added to the custom pulse sequence.

Abstract: A magnetic resonance system includes a magnetic resonance scanner having a multi-channel transmit coil or coil system and a magnetic resonance receive element; and a digital processor configured to perform an imaging process. The image process includes shimming the multi-channel transmit coil or coil system, acquiring a coil sensitivity map for the magnetic resonance receive element using the multi-channel transmit coil or coil system, acquiring a magnetic resonance image using the magnetic resonance receive element and the shimmed multi-channel transmit coil or coil system, and performing an intensity level correction on the acquired magnetic resonance image using the coil sensitivity map to generate a corrected magnetic resonance image.

Abstract: A magnetic resonance diagnostic apparatus includes a derivation unit to derive an apparent diffusion coefficient regarding a pixel position for each pixel position included in a region of interest in at least two original images obtained by imaging a same imaging region of a same subject using at least two b-factors that are different from each other, respectively, based on pixel values of each of at least two original images regarding the pixel positions, and a first estimation unit to estimate a pixel value obtained by using a b-factor that is different from the at least two b-factors, regarding each pixel position included in the region of interest, based on the apparent diffusion coefficient derived for each pixel position.

Abstract: A new and improved method for tracking and/or spatial localization of an invasive device in Magnetic Resonance Imaging (MRI) is provided. The invention includes providing an invasive device including a marker having a chemically shifted signal source with a resonant frequency different from the chemical species of the subject to be imaged, applying a pulse sequence, detecting the resulting RF magnetic resonance signals, and determining the 3D coordinates of the marker. The invention also includes generating scan planes and reconstructing an image from the detected signals to generate an image having the marker contrasted from the subject. The invasive device includes a marker having a chemically shifted signal source which has a resonant frequency different from the chemical species of the subject to be imaged for use in tracking the device during imaging.

Abstract: A method for detecting a virus in a patient based on imaging data includes scanning a region of interest of the patient with an imaging device and generating imaging data indicative of the region of interest, identifying at least one marker in the image data that corresponds to the virus based on the identified at least one marker and a set of predetermined imageable markers that correspond to the virus, classifying the virus as a particular strain of the virus based on a set of classification rules, and generating a signal indicative of the particular strain. The method optionally includes generating a signal indicative of the classification and electronically conveying the signal to at least one entity.

Abstract: A method for quantifying the development of pathologies involving changes in volume of a body represented via an imaging technique, including normalizing gray levels by a midway technique for two images I1 and I2 representing the same scene, resulting in two normalized images I?1 and I?2; calculating a map of signed differences between the two normalized images I?1 and I?2; and performing one or more statistical tests based on the assumption of a Gaussian distribution of the gray levels for healthy tissues in the normalized images I?1 and I?2 and/or in the calculated difference map. Advantageously, results of two or more of the tests can be combined for a more specific characterization of the development.

Abstract: In a method and device for automatic determination of a flow of a bodily fluid within vessels of an organism by a magnetic resonance, a magnetic resonance angiography to procedure is implemented generate magnetic resonance angiography images, a of magnetic resonance flow measurement is implemented to generate magnetic resonance flow images, and the magnetic resonance angiography images are applied to the magnetic resonance flow images as a mask to produce a resulting image depicting vessels with flow therein.

Abstract: A computer readable storage medium having a computer program stored thereon and representing a set of instructions that when executed by a computer causes the computer to calculate a mapping function that provides a location of each sub-volume of an imaging volume as a function of time from ultrasound data and determine a respective acquisition window for each sub-volume of the imaging volume from the mapping function. The instructions also cause the computer to reconstruct an image of the imaging volume substantially free of motion artifacts from imaging data acquired from the imaging volume.

Abstract: A method for characterizing regions on a map or image generated from diffusion image data of a region of a patient's body, including: loading into a data processing device image data achieved by calculation from MR diffusion imaging; providing a first threshold level to distinguish pixels with image data values that are above or below the values found that are not representative of pathological portions of the region; providing a second threshold level higher than the first threshold; deriving a measure related to the gradient pattern of those pixels that lie within a margin zone defined by those pixels that satisfy a criterion of the second threshold but do not satisfy a criterion of the first threshold and; outputting the measure related to the gradient as a parameter indicative of the likelihood that the pixels that are within the margin zone and/or a region of the body part are cancerous.

Abstract: An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine.

Abstract: Methods are provided herein for treating an individual having a disease, disorder or condition affecting the lungs, wherein said disease, disorder, or condition of the lung is an acute lung injury. In specific embodiments, the acute lung injury is chemical induced acute lung injury (CIALI). In some embodiments, the methods are provided for treating or protecting a subject from chemical induced acute lung injury that include administering to the subject a therapeutically effective amount of a phosphatase located on chromosome 10 (PTEN) inhibitor such as N(9,10-dioxo-9,10-di-hydrophenanthren-2-yl)pivalamide (SF1670). In some embodiments, the method products a subject from CAILI or reduces CAILI that results from a subsequent exposure to a chemical that induces chemical induced acute lung injury.

Abstract: Techniques for identifying individual target sites for application of transcranial magnetic stimulation (TMS) to a brain of a patient for treatment of neurological and psychiatric disorders. The identification of the target TMS stimulation sites may be based on using functional connectivity magnetic resonance imaging (fMRI) to determine cortex regions of the brain that are functionally connected to other regions of the brain that may be stimulated to decrease symptoms of depression and other disorders. For example, target stimulation sites may be identified in the left dorsolateral prefrontal cortex (DLPFC) to remotely modulate the activity in a subgenual cingulate region and other limbic regions functionally connected with the DLPFC. TMS may be applied to the patient's head at the identified target TMS sites to treat depression and other neurological and psychiatric disorders.

Abstract: What is provides is a brain activity deducing apparatus, a brain activity deducing method, a brain activity measuring apparatus, a brain activity measuring method, and a brain-machine interface device, capable of deducing a brain activity signal of a source subject. The information presentation device presents perceptible information to the first subject. The brain activity measurement device acquires a brain activity signal representing a brain activity of the first subject. The individual conversion device deduces a brain activity signal of the second subject from the acquired brain activity signal based on the individual conversion information, which correlates the brain activity signal of the first subject and the brain activity signal of the second subject.

Abstract: A apparatus includes an acquisition unit to acquire magnetic resonance data in every data group, a unit to control the acquisition unit to collect the data for one or a plurality of data groups during a collection period which is set based on a starting time phase of a cardiac cycle of the subject, a unit to determine the data among the data acquired by the acquisition unit as ineffective data if at least a part of it is related to a data group acquired during an ineffective period, and as effective data if all of it is related to a data group acquired during a period other than the ineffective period, the ineffective period being set based on an ending time point of the cardiac cycle in which the data is acquired, and a unit to reconstruct an image regarding the subject by using the effective data.

Abstract: An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing & diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio (SNR) by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra along regions associated with multiple chemicals that have been correlated to painful vs. non-painful discs.

Abstract: Presented in an embodiment is a local coil of an MRI system, including at least one cascade output slot, at least one cascade input slot, and at least one RF switch. The RF switch includes a first input signal interface, a second input signal interface, and at least one output signal interface, wherein the first input signal interface is connected to the cascade input slot, the second input signal interface is connected to a RF signal interface of the local coil, the output signal interface is connected to the cascade output slot. The RF switch is configured to output signals received by the first input signal interface and the second input signal interface from the output signal interface separately.

Abstract: A system automatically calculates optimal protocol parameters for dark-blood (DB) preparation and inversion recovery. The system automatically determines pulse sequence timing parameters for MR imaging with blood related signal suppression. The system comprises an acquisition processor for acquiring data indicating a patient heart rate. A pulse timing processor automatically determines an acquisition time of an image data set readout, relative to a blood signal suppression related magnetization preparation pulse sequence, by calculating the acquisition time in response to inputs including, (a) the acquired patient heart rate, (b) data indicating a type of image contrast of the pulse sequence employed and (c) data indicating whether an anatomical signal suppression related magnetization preparation pulse sequence used has a slice selective, or non-slice selective, data acquisition readout.

Abstract: The present invention is directed to a device and method for opening obstructed body internal passages and for sensing and characterizing tissues and substances in contact with the device. In general, the device comprises a catheter tube capable of inducing vibrations in a guidewire contained therein, wherein said vibrations of the guidewire are utilized for opening a passage through an occlusion. The in-vivo vibrations may be induced by means of a magnetic field actuating means and a guidewire comprising magnetic coupling means, or by means of transducers, which may be also used for the sensing. The invention also relates to the field of minimal invasive catheterization, particularly an apparatus for opening and/or removing obstructions occluding body internal passages by means of an active guidewire comprising a coil to which an alternating voltage can be applied. In that way the guidewire can vibrate if an external magnetic field is applied.