Abstract: An apparatus comprising a wearable device comprising a supporting structure, a sensor and an electronics module, wherein the supporting structure is configured to press the sensor against a skin surface of a subject, wherein the sensor is configured to detect a biological metric of the subject, and wherein the electronics module is configured to quantify and/or transmit one or more signal(s) corresponding to the biological metric. Some aspects relate to a method of monitoring a biological metric in a subject comprising: adorning a subject with the wearable device; and detecting the biological metric over a period of time in the subject with the wearable device. Other aspects relate to a method of treating a disease in a subject comprising: monitoring a biological metric in the subject over a period of time, and treating the subject with a therapeutic protocol, and monitoring the biological metric in the subject to assess treatment efficacy.

Abstract: A system and method for determining a stress level of a person is provided. The system creates a numerical solution to mathematical model of a blood pressure (BP) regulation, lumped mathematical model of a radial artery and partial differential equation (PDE) model of the radial artery. These models are then used to generate an inference engine using the mathematical model of blood pressure (BP) regulation, the lumped mathematical model of the radial artery and the PDE model of the radial artery. The inference engine is trained using an artificial neural network technique. At the same time the PPG signal of the person is sensed and preprocessed. The preprocessed PPG signal is then given to the trained inference engine. The trained inference engine generates a stress parameter corresponding to the person based on the processed PPG signal.

Abstract: Smart torquers are provided. Aspects of the smart torquers include: an engager for releasably engaging an elongated intravascular device; a communications module; a contact associated with the engager and configured to communicatively contact an elongated intravascular device engaged by the engager with the communications module; and a manipulator configured to allow a user to torque an elongated intravascular device engaged by the engager. Aspects of the invention further include methods of using the smart torquers, as well as systems and kits employed in such methods.

Abstract: The present application discloses an apparatus for determining a blood pressure of a subject, the apparatus includes a sensor assembly configured to measure a pulse wave signal of the subject; and a signal processor configured to generate a metric of the pulse wave signal based on the pulse wave signal, to select a blood pressure calculation algorithm base on the metric of the pulse wave signal, and to determine the blood pressure of the subject using the blood pressure calculation algorithm.

Abstract: A monitoring apparatus for monitoring a blood pressure information of a subject is disclosed. The monitoring apparatus comprises an ultrasound transducer for emitting ultrasound waves to a volume of the subject that includes a blood vessel and for receiving ultrasound waves from said volume of the subject, and for providing a first signal on the basis of ultrasound waves received from the volume of the subject. A light source is included for emitting light to the subject and a light sensor is included for detecting light received from the subject and for providing a second signal on the basis of the light received from a skin of the subject.

Abstract: Provided is an information processing device including: a sensor control unit configured to control a light emission intensity of a light source included in a pulse wave sensor on the basis of a state of a user who is a detection target of the pulse wave sensor.

Abstract: An operating method of an interactive service platform including the steps of: communicating with a plurality of user end devices via an application software; receiving physiological measurement information of user from the user end devices via the application software; analyzing the physiological measurement information to identify a physical and mental state/lifestyle of an associated subscriber; and automatically responding content information associated with at least one associated subscriber according to requests from the user end devices.

Abstract: A method for monitoring a cardiovascular pressure in a patient may include storing, in a memory of an implantable medical device system and in association with each one or more different patient postures, a respective offset value for the cardiovascular pressure of the patient. The one or more offset values may be determined based on a distance between an implantable pressure sensing device and an anatomical structure of the patient, a location of the implantable pressure sensing device within the patient, or one or more dimensions an anatomical structure of the patient. The method further includes determining a measured value of the cardiovascular pressure and a posture of the patient when the value of the cardiovascular pressure was measured, selecting a stored offset value associated with the current patient posture, and determining an adjusted cardiovascular pressure value based on the selected offset value and the measured cardiovascular pressure value.

Abstract: A monitoring device includes: a signal collection unit for collecting physiological parameters for representing a physiological status of a human body; a storage unit for storing guidance information of the physiological parameters, the guidance information corresponding to at least one measurement operation step of the physiological parameters; a processing unit for generating a monitoring interface for the physiological parameters and a measurement operation interface corresponding to current measurement operation step and for associating the guidance information corresponding to the current measurement operation step with the measurement operation interface; and a display unit for displaying at least one of the monitoring interface comprising the physiological parameters, the measurement operation interface, and the guidance information.

Abstract: A non-invasive sensor unit adapted to be coupled to a patient includes a pair of light emitters spaced apart a known distance, and a pair light detectors. The light detectors detect light emitted from the emitters and scattered by a patient. The unit determines one or more cardiovascular characteristics of the patient from the scattered light, such as the patient's pulse wave velocity; a saturation of peripheral oxygen (SpO2) level; a temperature; a respiration rate; a heart rate; and a blood pressure. The light emitters emit light that may have wavelengths between 600 and 1000 nanometers. The unit, in some embodiments, is integrated into a patch adapted to be secured to the skin of the patient. Readings from the unit may be transmitted to a separate device spaced from the unit, such as via Bluetooth, WiFi, or by other means.

Abstract: An apparatus for determining blood pressure has a control unit and a device for providing pulse wave data representative of a heartbeat of a human subject. The subject has a body height, an age, and a gender. The control unit is configured for receiving the pulse wave data, selecting a portion of the pulse wave data indicative of one or more heart periods, and, for each respective heart period of the one or more heart periods, determining a systolic component of the respective heart period, approximating the systolic component with a first Gaussian function and a second Gaussian function, and determining a time difference between the first and second Gaussian functions. The blood pressure value of the subject is determined based on the time difference, the body height, and the age.

Abstract: An apparatus for estimating biometric information is provided. According to one exemplary embodiment, the apparatus may include a sensor comprising an electrocardiogram (ECG) sensor configured to measure an ECG signal of a user and a pulse wave sensor configured to measure two or more pulse wave signals at two or more measurement sites of the user; and a processor configured to obtain biometric information based on the ECG signal and the two or more pulse wave signals measured by the sensor.

Abstract: Embodiments of the present disclosure are configured to assess the severity of a blockage in a vessel and, in particular, a stenosis in a blood vessel. In some particular embodiments, the devices, systems, and methods of the present disclosure are configured to collect and wirelessly distribute reliable pressure signals to other devices, and do so in a small, compact device that integrates with existing proximal and distal pressure measurement systems and does not require a separate power source.

Abstract: The invention provides compositions featuring TRP-4 polypeptides and polynucleotides, methods for expressing such polypeptides and polynucleotides in a cell type of interest, and methods for inducing the activation of the TRP-4 polypeptide in neurons and other cell types using ultrasound.

Abstract: The disclosure includes a system for sensing physiologic data. The system can include a flexible configured to wrap around a finger of a user, a first electrode coupled to the flexible strap, and a second electrode coupled to the flexible strap. The system can also include a sensor housing comprising at least one sensor configured to detect physiologic data from the finger and a data receiving module communicatively coupled to the first electrode, the second electrode, and the at least one sensor. The data receiving module can be configured to receive physiologic data from the at least one sensor.

Abstract: A system for monitoring blood pressure of a subject includes a primary system for determining a first blood pressure and a corrective system. The corrective system includes a cuff configured to be operated in an inflation phase and a deflation phase, a sensor array which produces inflation and deflation phase output signals, and a processor. The processor is configured to a) determine first and second output values from the inflation phase output signal and b) determine third and fourth output values from the deflation phase output signal. The processor is also configured to determine a correction applicable to the first blood pressure. The correction is a function of the first, second, third and fourth output values.

Abstract: The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool.

Abstract: A method and system for determining anaerobic threshold intensity (AnT) of a user in a freely performed physical exercise. A physiological response of a user is measured by heart rate and measured heart rate values are recorded as heart rate data. An external workload values are recorded and are each associated with one measured heart rate values to form a plurality of data points. The data points are filtered to form accepted data points, which are classified within a plurality of heart rate segments representing a heart rate within an anaerobic threshold (AnT) of the user. A data point with highest probability is stored for each segment. A first probability factor for each accepted data point is calculated. The calculated first probability factor is compared to a stored probability factor in each segment, and the higher probability factor is retained. AnT is calculated using the stored probabilities in each segment.

Abstract: The present invention provides a technique for continuous measurement of blood pressure based on pulse transit time and which does not require any external calibration. This technique, referred to herein as the ‘Composite Method’, is carried out with a body-worn monitor that measures blood pressure and other vital signs, and wirelessly transmits them to a remote monitor. A network of body-worn sensors, typically placed on the patient's right arm and chest, connect to the body-worn monitor and measure time-dependent ECG, PPG, accelerometer, and pressure waveforms. The disposable sensors can include a cuff that features an inflatable bladder coupled to a pressure sensor, three or more electrical sensors (e.g. electrodes), three or more accelerometers, a temperature sensor, and an optical sensor (e.g., a light source and photodiode) attached to the patient's thumb.

Abstract: Embodiments disclose a blood pressure parameter detection method. The method includes: detecting, by user equipment UE, an electrocardiogram ECG signal of a user by using a first ECG contact and a second ECG contact that are connected to an ECG detection circuit of the UE; when determining that the detected ECG signal matches a pre-stored reference ECG signal, enabling, by the UE, a photoplethysmogram PPG detection circuit, and detecting a PPG signal of the user by using a PPG detection point connected to the PPG detection circuit; and when determining that the detected PPG signal matches a pre-stored reference PPG signal, enabling, by the UE, a blood pressure detection application, and processing the detected ECG signal and the detected PPG signal by using the blood pressure detection application to obtain a blood pressure parameter of the user.

Abstract: A system configured to determine a characteristic of a patient includes a plurality of sensors, wherein each sensor of the plurality of sensors is configured to noninvasively determine a respective parameter of the patient, and wherein the parameter determined by each sensor is different from parameters determined by remaining sensors of the plurality of sensors. Such a system also includes a connector having a passage configured to direct pressurized fluid therethrough, wherein the plurality of sensors is connected to the connector.

Abstract: Systems and methods are provided for controlling lateral movement of a medical capsule system. A capsule housing is configured to be inserted into an anatomical structure of a patient. The multichannel tether is coupled to a rear of the capsule and includes at least one liquid exhaust channel conveying liquid to the capsule housing. The plurality of liquid exhaust ports are positioned around an outer circumference of the capsule housing and each configured to controllably expel liquid laterally from the capsule housing at varying rates to affect lateral movement of the capsule housing.

Abstract: A system having a processor obtain a digital hemodynamic data from a hemodynamic sensor, obtain one or more vital sign parameters characterizing vital sign data from the digital hemodynamic data, derive differential parameters based on the one or more vital sign parameters, generate combinatorial parameters using the one or more vital sign parameters and the differential parameters, determine a risk score corresponding to a probability of a future hypotension event for the living subject based on a weighted combination of a plurality of hypotension profiling parameters including the one or more vital sign parameters characterizing vital sign data, the differential parameters and the combinatorial parameters, and invoke a sensory alarm if the risk score satisfies a predetermined risk criterion.

Abstract: The present document describes a pressure guidewire. It comprises a shaft tube having a proximal section configured to provide pushability to the pressure guidewire; a middle section extending distally relative to the proximal section, the middle section comprising a cut pattern configured to provide greater flexibility in the middle section than the proximal section; and a sensor housing section extending distally relative to the middle section. The pressure guidewire further comprises an inner hypotube comprising a proximal end portion and a distal end portion, the inner hypotube positioned entirely radially inward of the shaft tube and within at least the middle section, the proximal end portion and the distal end portion of the inner hypotube being joined to the shaft tube; and a tip pressure sensor positioned in the sensor housing section.

Abstract: Disclosed is ischemic precondition treatment equipment and a use and method thereof for judging health condition of blood vessels. A gas way structure (4) is arranged inside a shell of ischemic precondition training treatment equipment. The gas way structure comprises a 5-way device (43). The 5-way device (43) is connected to a left gas pump (41), a right gas pump (42), a left solenoid valve (44), a right solenoid valve (45) and a release valve (48), respectively. The gas way structure (4) can rapidly bring a pressure of an armband airbag to the set pressure value in a short period of time, which is effective in relieving the patients' discomfort and pain when used. It is suitable for long-term use for training. In addition, it also can judge the health condition of blood vessels.

Abstract: A blood pressure measurement device is equipped with a pressing surface which is formed with an element array of plural pressure sensors arranged in one direction and an element array of plural pressure sensors arranged in the one direction, an air bag for pressing the pressing surface against a living body, a control unit for calculating blood pressure values in a radius artery on the basis of pressure pulse waves that are detected by the pressure sensors in a state that the pressing surface is pressed against the living body by the air bag, and a rotational drive unit for performing driving to rotate the pressing surface about each of axes that are perpendicular to a pressing direction of the air bag.

Abstract: A non-contact blood-pressure measuring device includes: an image acquiring section that acquires a skin image obtained by capturing skin of a user; a pulse-wave timing calculating section that calculates, as a pulse-wave timing, time information indicative of a time at which time-varying luminance in the skin image reaches a peak; a millimeter-wave acquiring section that acquires a signal of a radio wave reflected by the user; a heartbeat timing calculating section that calculates, as a heartbeat timing, time information indicative of a time at which a time-varying distance to the user obtained on the basis of the signal of the radio wave acquired by the millimeter-wave acquiring section reaches a peak; and a blood-pressure determining section that determines blood pressure of the user on the basis of a time difference between the pulse-wave timing and the heartbeat timing.

Abstract: The present application relates to systems and methods for non-invasively determining at least one of left ventricular end diastolic pressure (LVEDP) or pulmonary capillary wedge pressure (PCWP) in a subject's heart, comprising: receiving, by a computer, a plurality of signals from a plurality of non-invasive sensors that measure a plurality of physiological effects that are correlated with functioning of said subject's heart, said plurality of physiological effects including at least one signal correlated with left ventricular blood pressure and at least one signal correlated with timing of heartbeat cycles of said subject's heart; training a machine learning model on said computer using said plurality of signals for periods of time in which said plurality of signals were being generated during a heart failure event of said subject's heart; determining said LVEDP or PCWP using said machine learning model at a time subsequent to said training and subsequent to said heart failure event.

Abstract: A method and system for estimating physiological heart measurements from medical images and clinical data disclosed. A patient-specific anatomical model of the heart is generated from medical image data of the patient. A patient-specific multi-physics computational heart model is generated based on the patient-specific anatomical model by personalizing parameters of a cardiac electrophysiology model, a cardiac biomechanics model, and a cardiac hemodynamics model based on medical image data and clinical measurements of the patient. Cardiac function of the patient is simulated using the patient-specific multi-physics computational heart model. The parameters can be personalized by inverse problem algorithms based on forward model simulations or the parameters can be personalized using a machine-learning based statistical model.

Abstract: The present application discloses a blood pressure measurement device, includes: a blood pressure measurement body configured to measure blood pressure based on photoplethysmogram (PPG); and a calibrator configured to measure blood pressure values based on Korotkoff sounds. The calibrator is further configured to provide initial calibration parameters to the blood pressure measurement body, and the blood pressure measurement body is further configured to collect an ECG signal and a PPG signal, calibrate a PPG parameter-blood pressure equation according to the initial calibration parameters, and calculate a blood pressure value according to the PPG parameter-blood pressure equation.

Abstract: A system for collecting data for assessment of cardiovascular function includes a plurality of monitoring devices coupled to different respective body parts. Each monitoring device is configured to measure a respective signal at the respective body part in response to cardiovascular activity. The respective signal includes a cardiovascular component attributable to the cardiovascular activity and an artifact component not attributable to the cardiovascular activity. When the monitoring devices measure the respective signals simultaneously over a same time period, the cardiovascular components are correlated, and the artifact components are not correlated.

Abstract: A wrist-worn device heart-monitoring device is presented. The wrist-worn heart-monitoring device includes a radial tonometer configured to output a pressure signal indicating a pulse pressure wave at a user's wrist, two or more electrodes configured to output an electrical signal indicating a user's heart has been commanded to contract, and a microphone configured to output an audio signal indicating a closing of a user's aortic valve. The wrist-worn heart-monitoring device further includes a pulse transit time monitor configured to calculate a pre-ejection period of the user's heart based on at least the pressure, electrical, and audio signals, and calculate a pulse transit time based on at least the pre-ejection period, the pressure signal, and the electrical signal.

Abstract: The present invention generally relates to blood pressure monitoring. In some embodiments, methods and devices of measuring a mean arterial pressure are provided and/or monitoring blood pressure changes. A wrist-worn device may include a plurality of sensors backed by a plurality of actuators. Subsets of the plurality of sensors may be selectively actuateable against a wrist of a user using one or more of the plurality of actuators. A preferred sensor and location may be identified based on pressure signals received from each of the sensors. In some embodiments, devices may use a fluid bladder coupled with piezoelectric film sensors. A fluid bladder pressure sensor may be used to calibrate the piezoelectric film signal to provide a static and dynamic pressure reading. In yet another embodiment, a mean arterial pressure may be calculated by processing a swept pressure signal obtained as a sensor is swept through different heights.

Abstract: A multi-lumen catheter can be used to measure pressure at multiple locations within the vasculature. The multi-lumen catheter can include multiple segments, such as a proximal portion, an intermediate portion, and a distal portion. A segment of a multi-lumen catheter may differ from another segment of the same multi-lumen catheter in radiodensity, hardness, and/or some other characteristic. Some multi-lumen catheters are designed to permit measurements of pressure in different lumens.

Abstract: Wearable pulse pressure wave sensing devices are presented that generally provide a non-intrusive way to measure a pulse pressure wave travelling through an artery using a wearable device. In one implementation, the device includes an array of pressure sensors disposed on a mounting structure which is attachable to a user on an area proximate to an underlying artery. Each of the pressure sensors is capable of being mechanically coupled to the skin of the user proximate to the underlying artery. In addition, there are one or more arterial location sensors disposed on the mounting structure which identify a location on the user's skin likely overlying the artery. A pulse pressure wave is then measured using the pressure sensor of the array closest to the identified location.

Abstract: The present invention provides an image based blood pressure monitoring method, comprising: acquiring at least a human image information of at least a human skin area; according to the human image information to locate at least a ROI; extracting the human image information of the ROI, and calculate; filtering the average value of the human image information; monitoring the filtered signal; calculating an image pulse transmit time of the filtered signal, and calculating an inter-beat interval of the filtered signal; and employ the specific prediction model, to calculate a systolic pressure value and a diastolic pressure value.

Abstract: Disclosed are systems and methods for using one or more light sources and associated photodetectors to determine different physiological parameters of a subject based on the subject's activity state. A processor may, for example, be configured to determine, based at least in part on data received from an accelerometer at a first time, that a first physiological parameter of the subject is to be determined, to cause the light source(s) to operate in a first manner and process signals from the photodetector(s) to determine the first physiological parameter, to determine, based at least in part on data received from the accelerometer at a second time, that a second physiological parameter of the subject is to be determined, and to cause the light source(s) to operate in a second manner and process signals from the photodetector(s) to determine the second physiological parameter.

Abstract: To perform measurement of a vascular elasticity rate with high accuracy in a short time. A vascular elasticity rate evaluation apparatus of the present invention includes: a pressure detection unit that detects a pulse wave with an external pressure being applied to a blood vessel; and a control unit that forms a pulse wave amplitude indicating dependent characteristics due to elasticity of the blood vessel from a detection value of the pressure detection unit, calculates a plus area in an elevation process of the pulse wave amplitude and a minus area in a descent process thereof, and calculates the vascular elasticity rate using values thereof.

Abstract: An implantable device with in vivo functionality, where the functionality of the device is negatively affected by ROS typically associated with inflammation reaction as well as chronic foreign body response as a result of tissue injury, is at least partially surrounded by a protective material, structure, and/or a coating that prevents damage to the device from any inflammation reactions. The protective material, structure, and/or coating is a biocompatible metal, preferably silver, platinum, palladium, gold, manganese, or alloys or oxides thereof that decomposes reactive oxygen species (ROS), such as hydrogen peroxide, and prevents ROS from oxidizing molecules on the surface of or within the device. The protective material, structure, and/or coating thereby prevents ROS from degrading the in vivo functionality of the implantable device.

Abstract: Methods for diagnosing and/or treating a multi-lesion intravascular region are disclosed. The methods may include advancing a pressure sensing device to a first position that is distal of a first lesion and that is distal of a second lesion, proximally retracting the pressure sensing device to a second position that is proximal of the first lesion and that is proximal of the second lesion, calculating a first estimated post-treatment fractional flow reserve based on treatment of the first lesion, calculating a second estimated post-treatment fractional flow reserve based on treatment of the second lesion, and treating the first lesion, the second lesion, or both based on the first estimated post-treatment fractional flow reserve and the second estimated post-treatment fractional flow reserve.

Abstract: The invention relates to the field of cardiovascular resuscitation and, more specifically, it concerns a novel method of monitoring the ventriculo-aortic coupling of at-risk patients on the basis of the aortic pressure/flow loop of the patient and the zoning of this loop.

Abstract: Apparatus and methods for determining a type of a material in a region within a vascular system of a patient and/or a distance to the material are provided. At least one source fiber is provided that supplies light from a light source to a region within a vascular system of a patient. At least one return fiber is provided to receive light reflected from the region within the vascular system. At least one controller is provided to determine at least one property of the region within the vascular system from the reflected light, and to determine a type of a material in the region within the vascular system and/or an indication of a distance to the material. Techniques such as laser ablation may then be performed based on the determined material type and/or distance to remove unwanted buildup, deposits, etc., while avoiding harmful results such as tearing of tissue.

Abstract: Systems and methods for non-invasive blood pressure measurement are disclosed. In some embodiments, a system comprises a wearable member configured to generate first and second signals (e.g., PPG signals), and a blood pressure calculation system. The blood pressure calculation system includes a wave selection module configured to identify subsets of waves of the signals, a feature extraction module configured to generate sets of feature vectors form the subsets of waves, and a blood pressure processing module configured to calculate an arterial blood pressure value based on the sets of feature vectors and an empirical blood pressure calculation model, the empirical blood pressure calculation model configured to receive the sets of feature vectors as input values. The blood pressure calculation system further includes a communication module configured to provide a message including or being based on the arterial blood pressure value.

Abstract: Provided is a drive unit for an auto-injector having a drive unit housing arranged for docking receipt of a syringe or of a cassette unit comprising a syringe movable from a rest position, in which a needle tip of the syringe is within the drive unit housing to a use position, in which the needle tip protrudes from a needle delivery aperture; and a drive arrangement including one or more electrically powered sources of axial drive; a first drive transfer element for advancing the syringe to said use position; and a second drive transfer element for moving a plunger into the barrel of the syringe to eject liquid contents thereof. The drive unit housing is provided with a skin sensor arrangement having an array of plural skin sensor electrodes located about the needle delivery aperture.

Abstract: A non-invasive, optical-based physiological monitoring system is disclosed. One embodiment includes an emitter configured to emit light. A diffuser is configured to receive and spread the emitted light, and to emit the spread light at a tissue measurement site. The system further includes a concentrator configured to receive the spread light after it has been attenuated by or reflected from the tissue measurement site. The concentrator is also configured to collect and concentrate the received light and to emit the concentrated light to a detector. The detector is configured to detect the concentrated light and to transmit a signal representative of the detected light. A processor is configured to receive the transmitted signal and to determine a physiological parameter, such as, for example, arterial oxygen saturation, in the tissue measurement site.

Abstract: Embodiments of the disclosure are directed to methods, apparatuses, and computer program products for determining a hemodynamic parameter. An exemplary method comprises: receiving data associated with at least one heart beat; calculating a first standard deviation for at least a portion of the data; interpolating a second standard deviation for at least a second portion of the data; and determining the hemodynamic parameter based on the first standard deviation and the second standard deviation.

Abstract: A wearable device and a method of providing user interaction with the wearable device is provided. The method includes receiving one or more signals from at least one of one or more pressure sensors and one or more vibration sensors, obtaining information related to at least one of an orientation of the wearable device on a user hand and a hand on which the wearable device being worn based on the one or more signals received, and performing one or more functions based on the obtained information.

Abstract: A transducer modulus, comprising: a supporting substrate; a cap, which is arranged on the supporting substrate and defines a chamber therewith; a pressure transducer in the chamber; an acoustic transducer in the chamber; and a processing chip, or ASIC, operatively coupled to the pressure transducer and to the acoustic transducer. The pressure transducer and the acoustic transducer are arranged on top of one another to form a stack.

Abstract: In an embodiment, a seizure monitor provides intelligent epilepsy seizure detection, monitoring, and alerting for epilepsy patients or people with seizures. In an embodiment, the seizure monitor may be a wearable, non-intrusive, passive monitoring device that does not require any insertion or ingestion into the human body. In an embodiment, the seizure monitor may include several output options for outputting the accelerometer/gyro or other motion sensor data and video data, so that the data may be immediately validated and/or remotely viewed. The device alerts are communicated to the outside care givers via wireless or wired medium. The device may also support recording of accelerometer or other motion sensor data and video data, which can be reviewed later for further analysis and/or diagnosis. The device and invention is also used and applicable for other body motion disorders or detection and diagnostics.

Abstract: The present invention provides a sphygmomanometer system, including a measurement device pressed against a predetermined part to be measured so that the part to be measured is held down, and a blood pressure measurement device to measure blood pressure based on information from the measurement device. The measurement device includes an average blood pressure detection unit to obtain information on pressure applied to the measurement device, and a blood pressure change amount detection unit to detect a minute change of the part to be measured when the blood pressure change amount detection unit contacts with the part to be measured. The processor of the blood pressure measurement device calculates the average blood pressure, the highest blood pressure, and the lowest blood pressure based on information on pressure obtained from the blood pressure change amount detection unit and the average blood pressure detection unit.