Abstract: Exemplary embodiments provide automatic injection devices in which a shroud is automatically deployed to protectively sheath a needle after an injection is performed. Exemplary embodiments also provide shroud deployment assemblies including a shroud and a syringe carrier that, when cooperatively configured in an automatic injection device, ensure that the shroud is automatically and completely deployed after an injection is performed using the automatic injection device. Exemplary embodiments are also configured to ensure that, once the shroud is deployed to an extended position to sheath the needle, accidental forces applied to the shroud do not succeed in subsequently retracting the shroud to a retracted position in which the needle would become exposed.

Abstract: The invention relates a safety IV catheter assembly comprising a catheter tube having a distal end and a proximal end; a catheter hub having a distal end and a proximal end; a needle extending through the catheter hub and the catheter tube having opposite proximal and distal ends defining an axial direction A, wherein the proximal end is joined to the needle hub and the distal end forms a needle tip and a change in profile is provided between the proximal and distal ends of the needle; and a tip protector assembly being arranged movably on the needle in-between the catheter hub and needle hub outside the catheter hub in an arrangement engaging with one or more second locking means provided on the catheter hub in its ready position, wherein the first arm is deflected radially outwards by the needle against a restoring force, wherein the tip protector assembly is configured to entrap the needle tip upon withdrawal of the needle from the catheter hub.

Abstract: The present invention discloses a disposable safety self-destruction insulin needle. The invention uses a sleeve-connected linkage structure and realizes an instant reset of the safety sleeve by means of the spring located in the middle axis so as to ensure that the needle tube is not exposed and preferably realizes a tilting and deflection of the self-destruction pressure base due to a plurality of flexible plates unevenly distributed on the inner wall in the needle base so as to finally ensure that the insulin needle cannot be used a second time, in so doing the safety self-destruction operation of the insulin needle is realized.

Abstract: An apparatus includes a body, a needle, a catheter, and an actuator assembly. The needle extends distally from the body. The needle has an inner wall defining a needle lumen. The needle lumen is in fluid communication with a fluid port of the body. The catheter is slidably disposed in the needle lumen. The catheter has a catheter lumen. The first actuator assembly is configured to translate the catheter within and relative to the needle. The apparatus may also include an actuator assembly that is configured to rotate the needle relative to the body. The apparatus may be used to first deliver a leading bleb of fluid to the subretinal space in a patient's eye via the needle. The apparatus may then be used to deliver a therapeutic agent to the subretinal space in the patient's eye via the catheter.

Abstract: A folding panel needle guard comprises front and rear panels coupled together at hinges, a collar attached to the front panels at hinges, a guard base element coupled to the rear panels at hinges, a hub and a spring to unfold and lock the front and rear panels in a co-linear needle shielded configuration. The folding panel needle guard is mountable to a needle or syringe assembly.

Abstract: A system for injecting a fluid medicament into a patient includes a drive mechanism, and a cassette loaded with a pre-filled hypodermic syringe. When the cassette is loaded, the syringe is held firmly inside and the cassette can be selectively engaged with the drive mechanism. The drive mechanism has two motors. A first motor initially moves the hypodermic syringe from a position inside the cassette where its needle is concealed, to a position where the needle extends from the cassette for insertion into a patient for an injection. With the needle inserted, a second motor pushes the syringe stopper to expel a fluid medicament from the syringe. After an injection, the first motor withdraws the syringe back into concealment inside the cassette, to again firmly hold the syringe on the cassette. The cassette and syringe, in combination, can then be removed from the drive mechanism and discarded.

Abstract: A safety needle device includes a housing including a passageway with a needle cannula extending therefrom. A shielding member is movable between a first position in which a puncture tip of the needle cannula is exposed therefrom and a second position in which the puncture tip of the needle cannula is encompassed therein. The shielding member is maintained in the first position against a biasing force which biases the shielding member toward the second position. A fluid and/or a temperature activation material is associated with the shielding member and is adapted to deform upon contact with a fluid medium and/or a certain temperature or temperature range. The fluid medium flowing through the needle cannula causes the fluid activation material to deform, such as through expansion, thereby releasing the shielding member from the first position and allowing a drive member to bias the shielding member toward the second position.

Abstract: One embodiment is directed to a safety syringe system, comprising: an off-the-shelf syringe assembly comprising a syringe body and a plunger tip; a needle assembly removably coupleable to the distal end of the syringe body such that medicinal fluid may be transferred through a retractable needle coupled to a needle housing comprising the needle assembly upon insertion of the plunger tip relative to the syringe body; and a plunger control assembly coupled to the plunger tip and configured to facilitate manual insertion of the plunger tip relative to the syringe body; wherein upon insertion of the plunger tip to a final insertion state and release of an associated manual insertion load, the plunger tip may be proximally withdrawn, pulling the retractable needle proximally relative to the needle housing to a safe locked and retracted state wherein it is no longer exposed for injection.

Abstract: A drug delivery device (100), including a body (104, 116) having a reservoir (164, 176) disposed therein for containing a medicament and an injection needle (152) for penetrating the skin of a patient, the needle (152) providing a path for the medicament between the reservoir (164, 176) and the patient. The device (100) also includes a needle cover (114) for selectively covering the injection needle (152), an adhesive (264) for selectively adhering the device to the patient, a release liner (500) for selectively covering a patient side of the adhesive (264), and a connecting means (112, 520, 512, 508, 524) for connecting the needle cover (114) and the release liner (500) such that removal of one of the needle cover (114) and the release liner (500) from the device (100) removes the other one of the needle cover (114) and the release liner (500).

Abstract: A liquid administration device includes an inner structure that includes a cylindrical body that has a bottom part in a distal portion thereof and an opening portion in a proximal portion thereof, a needle tube that is mounted in the distal portion of the cylindrical body and has a sharp needle tip at a distal end and a proximal end of which is communicatable with an inside of the cylindrical body, and a gasket that is located in the cylindrical body; an operation member that includes a plunger, the operation member being configured to perform a pressing operation in which the plunger is moved relative to the cylindrical body in a distal direction while being pressed; an engagement portion that includes: a first engagement portion and a second engagement portion.

Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on the injector device, or on a portion of the injection device housing, or on a drug reservoir. Some devices may be removably attached to a drug reservoir, for example, through a luer connector. Other devices may comprise internal luer seal for securely connecting a drug conduit of the device to the luer cavity of a drug reservoir. Yet other devices may comprise a priming-enabling element to facilitate the drug priming of a shielded needle. Related methods and systems comprising the devices are also described.

Abstract: Described is an injection device for administering a dose of a medicament (M) comprising a carrier adapted to contain a syringe having a hollow injection needle and a stopper, a drive spring, a plunger adapted to forward load of the drive spring to the stopper, and a noise component adapted to generate an audible and/or tactile feedback by impacting a component of the injection device when the stopper is located at a proximal end of the syringe. In a first state, a resilient arm on the plunger is maintained in engagement with the noise component by the carrier. In a second state, the arm disengages the noise component and deflects at least partially into an aperture in the carrier.

Abstract: Needle hub assembly (200) for a syringe (100), said assembly having a longitudinal axis (L1) comprising:—a needle hub body (210) having a syringe connector (212) for receiving an attachment member (110) of a syringe (100) at a first end (210a) of the body (210) and a needle receiving portion (214) at a second opposing end (210b) of the body (210),—a needle (216) extending from the needle receiving portion (214), wherein the syringe connector (212) comprises a substantially conical receiving opening (218) for receiving a syringe attachment member (110), at least a distal end (110b) thereof, wherein a length (A) of said opening (218), measured along the longitudinal axis (L1), is approximately 6.1+0.05 mm.

Abstract: A microneedle injection apparatus comprising a dual cover. The apparatus can include a housing having a base and a cavity; a microneedle array comprising a first side comprising a plurality of microneedles; and a microneedle array holder configured to hold a microneedle array and located in the housing. The microneedle array holder can be movable between a retracted position, and an extended position. The apparatus can further include a cover (113) configured to be positioned to cover the opening (115) in the base (112) of the housing. The cover can include (i) a first portion (140) configured to cover at least a portion of the base of the housing adjacent the opening, and (ii) a second portion (142) configured to be received in the cavity of the housing and further configured to cover the plurality of microneedles on the microneedle array when the microneedle array holder is in the retracted position.

Abstract: The invention is related to an apparatus comprising a dispense interface for use with a drug delivery device, the dispense interface comprising a lockout element being arranged at least partially between an outer body of the dispense interface and an inner body of the dispense interface and wherein the lockout element is configured to be removeably maintained in a first position, such that when the dispense interface is first attached and then removed from said drug delivery device, the lockout element moves into a second position, wherein the lockout element in the second position is configured to prevent said dispense interface from being reattached to a drug delivery device.

Abstract: A medicament delivery device has proximal and distal ends; a medicament container with a plunger, a neck portion, and a delivery member unit; a housing extending along a longitudinal axis with proximal and distal open ends; a drive unit configured to apply a force on the plunger; and a C-shaped tubular body with a longitudinal slit/gap such that body can be attached to the neck portion forming a container unit. The C-shaped body also has an inner support configured to interact with the neck portion and with the delivery member unit and prevent the medicament container from moving relative to the body after the medicament container is attached to the body, and outer support configured to interact with a corresponding support of the housing to prevent the C-shaped tubular body from moving relative to the housing after the container is arranged within the housing through the distal open end.

Abstract: A medicated module (4) for an injection system to co-deliver at least two medicaments is disclosed where a primary delivery device containing a primary medicament accepts a medicated module (4) containing a single dose of a secondary medicament and where both medicaments are delivered through a hollow needle (3). The medicated module (4) does not require the user to manually engage a reservoir (22) containing the secondary medicament. Instead, a biasing member (48) automatically activates the reservoir (22) when the needle guard (42) is retracted. The needle guard (42) prevents accidental needle sticks before and after an injection, and locks after dose delivery.

Abstract: A surgical system for treating urinary incontinence includes an introducer needle and a handle. The introducer needle has a first section that is straight and is provided with a first flat, a second flat opposite the first flat, and a latch receptacle formed into the first section. The introducer needle has a second section extending from the first section, with the second section being curved. The handle includes a housing with a needle opening configured to receive the first section of the introducer needle and a latching mechanism that includes a latch member. The latching mechanism is configured to engage the latch receptacle of the introducer needle.

Abstract: A syringe includes a barrel having an internal surface defining an internal bore therein, and a plunger disposed within the internal bore of the barrel. A distal end of the plunger is inserted into a proximal end of the barrel. At least one radial projection is disposed on an external surface of the plunger, the at least one radial projection includes a proximal ramp and a distal ramp. The distal ramp includes a first point being a point of incipient contact with the internal surface of the barrel, and the at least one radial projection has a first slope relative to the longitudinal axis at the first point. The at least one radial projection has a second slope at a second point along the proximal ramp. An absolute value of the first slope is different from an absolute value of the second slope.

Abstract: The present invention concerns a medical pump comprising: a. A hard housing comprising a top (24) and bottom (1) hard shells, within which a rigid wall (3) and a movable membrane (2) create three distinct chambers; wherein i. said movable membrane tightly separates said second (29) and third (22) chambers ii. said first and third chambers have a watertight interface iii. said second chamber (29) is designed to contain a fluid iv. said first chamber (23) comprises a first venting mean (20) which is arranged to provide a fluidic communication between said first chamber (23) and the external environment; v. said third chamber (22) comprises a second venting mean which is arranged to provide a fluidic communication between said third chamber (22) and the external environment b. A pumping element (4) located in the first chamber (23) c. A least one pressure sensor which measure the pressure gradient between the first chamber (23) and the second chamber (29) d. A fluid pathway which permits: i.

Abstract: The present invention relates to an autoinjector device (10) for use in combination with a syringe (30), said syringe comprising a movable plunger; a needle; and a tubular needle shield (34). The claimed autoinjector device (10) comprises: an elongated housing having a proximal (11) and a distal end (12); a drive mechanism; a syringe holder (40) in order to support the fragile syringe and to prevent damage to the syringe. The invention furthermore relates to a method for assembly of the autoinjector device according to the invention.

Abstract: A syringe assembly includes a barrel including a barrel body portion, a cylindrical barrel end portion disposed at a distal end of the barrel body portion, the cylindrical barrel end portion including an annular head portion and an annular recessed portion, and a puncture needle having a puncture needle tip and having a proximal end fixedly inserted into the barrel end portion; and a seal cap mounted to the barrel, the seal cap including a closed distal end portion, an open proximal end portion, a hollow portion including (i) a barrel end storage portion, the barrel end storage portion being configured to store the barrel end portion, and (ii) a puncture needle storage portion extending from a distal end of the barrel end storage portion, an insertion portion configured to receive the puncture needle tip, and a projection portion formed on an inner surface of the barrel end storage portion.

Abstract: One embodiment is directed to a pre-filled safety syringe system, comprising a syringe body; a plunger tip positioned within the syringe body; a needle assembly removably coupleable to the distal end of the syringe body such that a medicinal fluid may be transferred through a retractable needle coupled to a needle housing comprising the needle assembly upon insertion of the plunger tip relative to the syringe body; and a plunger control assembly coupled to the plunger tip and configured to facilitate manual insertion of the plunger tip relative to the syringe body; wherein upon insertion and release of the plunger tip, a retraction load coupled between the syringe body and the plunger tip causes the plunger tip to be proximally withdrawn, pulling the retractable needle proximally relative to the needle housing to a safe locked and retracted state.

Abstract: One embodiment is directed to a safety syringe system, comprising a syringe body; a plunger tip positioned within the syringe body; a needle assembly removably coupleable to the distal end of the syringe body such that a medicinal fluid may be transferred through a retractable needle coupled to a needle housing comprising the needle assembly upon insertion of the plunger tip relative to the syringe body; and a plunger control assembly coupled to the plunger tip and configured to facilitate manual insertion of the plunger tip relative to the syringe body; wherein the needle assembly comprises a needle housing member removably coupled to the retractable needle and also removably coupled to a needle cover, the needle cover providing a relatively large geometric guiding surface for aligning a proximal end of the retractable needle as it is guided into fluidic contact with the fluid reservoir of the syringe body.

Abstract: A removal device (121, 221) for removing and disposing of a pen needle (113, 213) connectable to a drug delivery device (111, 211) includes a body (123, 223) having a cavity (141, 241) for receiving the pen needle of the drug delivery device such that a patient end (116, 216) of a needle (115, 215) of the pen needle is covered by the body. An ejector (151, 251) is movably connected to the body (123, 223) for engaging the received pen needle (113, 213) and selectively ejecting the engaged pen needle from the body. The pen needle (113, 213) is securely retained within the removal device (121, 221) without exposing the needle (115, 215) of the pen needle until the pen needle (113, 213) can be properly disposed of, such as in a sharps container, thereby substantially preventing an accidental needle stick.

Abstract: An automatic needle device comprises a body into which a needle assembly and needle are mounted. The device also includes a needle guard to cover the needle until it is used and to lock over the needle after use so the needle is not re-exposed. The locking is accomplished with a coil spring action locking device. A container for holding the automatic needle device also facilitates the viewing of the distal end of the needle prior to use on a patient.

Abstract: A syringe for use with a medical injector system includes a barrel and a semi-rigid hub, the hub having an outer surface adapted to slidingly move within the barrel, and an inner surface having a continous circumferential wall. The hub further includes an annular engaging portion recessed within at least part of the continous circumferential wall forming a groove, at least one radially extendable and retractable retention member disposed at partially within a proximal cylindrical portion of the hub, and the elastometric seal engaged with a seal engaging portion on the hub and slidingly engaged with the barrel of the syringe. The semi-rigid hub and the elastomeric seal are reciprocally slidable within the barrel, and the at least one radially entendable and retractable retention member is configured to releasably engage the groove upon retraction of the plunger to permit the semi-rigid hub to be selectively withdrawn within the barrel.

Abstract: An injection device (100), including a base (104), a sliding body (116) slidably connected to the base (104), a double-ended needle (120) fixed to the sliding body (116), a biasing member (124) for proximally biasing the sliding body (116) with respect to the base (104), and for retracting the needle (120) into the device (100) subsequent to activation of the device (100), a medicament cartridge (128) for holding a medicament, slidably connected to the sliding body (116), and a stopper (132) slidably disposed within the medicament cartridge (128). The base (104) has a proximal end (108) and a surface (164) disposed at a distal end (112) thereof for contacting a patient's skin. The base (104) also has a first locking mechanism. The sliding body, (116) has a locking feature and a second locking mechanism. The second locking mechanism locks the medicament cartridge (128) relative to the sliding body (116) upon completion of displacement of the medicament cartridge (128) relative to the sliding body (116).

Abstract: A medical safety needle includes a needle body having a needlepoint, a covering body having a detent portion slidable on the needle body to catch the needlepoint so as to cover the needlepoint, and a resilient cantilever supporting the detent portion, a collar portion slidably fitting on the covering body, which is configured to get in contact with the cantilever to press the cantilever radially inwardly, and a housing being formed in a unitary body with the collar portion or having an end face on which the collar portion is capable of being seated, the housing being configured to carry the covering body from a first position to have the needlepoint exposed to a second position to have the needlepoint covered by the covering body.

Abstract: Provided herein is a plunger assembly for advancing a plunger through a barrel, such as the barrel of a pre-filled syringe. The plunger assembly includes a stopper adapter defining an aperture. The stopper adapter includes a first restraining member adjacent to the aperture. The plunger assembly also includes a plunger rod having a first end, a second end, and a plunger rod head disposed adjacent the first end of the plunger rod. The plunger rod head includes a second restraining member engageable with the first restraining member of the stopper adapter. The plunger assembly is configured such that as the plunger rod head is moved axially within the aperture of the stopper adapter, the first restraining member of the stopper adapter engages the second restraining member of the plunger rod head to secure the plunger rod head within the aperture. A syringe assembly with a plunger assembly is also disclosed.

Abstract: One embodiment is directed to a method for safe injection, comprising: providing an injection assembly and inserting a plunger tip of the injection assembly to a final insertion state and releasing an associated manual insertion load. A retraction load developed sufficient to cause the plunger tip to be proximally withdrawn pulls the retractable needle proximally relative to the needle housing to a retracted state wherein a distal tip of the needle becomes mechanically locked into an encapsulated configuration wherein it is no longer exposed for injection.

Abstract: One embodiment is directed to a safety syringe system, comprising a syringe body; a plunger tip positioned within the syringe body; a needle assembly removably coupleable to the distal end of the syringe body such that a medicinal fluid may be transferred through a retractable needle coupled to a needle housing comprising the needle assembly upon insertion of the plunger tip relative to the syringe body; and a plunger control assembly coupled to the plunger tip and configured to facilitate manual insertion of the plunger tip relative to the syringe body; wherein upon insertion and release of the plunger tip, a retraction load coupled between the syringe body and the plunger tip causes the plunger tip to be proximally withdrawn, pulling the retractable needle proximally relative to the needle housing to a safe locked and retracted state.

Abstract: An autoinjector includes a housing for receiving in use in a generally longitudinal loading direction a syringe assembly including a syringe carrier and a syringe, the syringe including a syringe body having a slideable internal piston for expressing a dose contained in the body through a needle at a forward end thereof; a drive mechanism for providing drive for operation of the autoinjector and being disposed generally within the housing and including a mechanical energy source and a winder element for being rotated to charge the energy source, and an input transmission train operational between the syringe assembly and the winder element in use, whereby loading of the syringe assembly into the housing rotates the winder element to charge the energy source.

Abstract: The present disclosure describes an extended finger flange that facilitate use of syringe systems. The extended finger flange increases the surface area available for an end user's fingers thereby allowing a more secure grip on the device and providing greater control during administrations of the medication.

Abstract: A fluid delivery device includes an automatic needle retraction mechanism configured to automatically retract a delivery end of a needle into a housing. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon an actuator moving from the first position to the second position. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon decoupling a bottom surface of the housing from a skin surface.

Abstract: Medical device assemblies having a connection mechanism for securely connecting a hub to fluid storage containers in a luer slip relationship are described. An exemplary medical device includes a hub forming a cavity, a second indicating element disposed within the cavity that engages the hub. Additional features of the medical device include a second indicating element contoured to form a line contact with the hub. In a specific configuration, the hub includes a first indicating element attached to the hub and extending proximally into the cavity having a protrusion. In a more specific configuration, the medical device includes a fluid storage container that has an indication system for visually indicating optimal fluid-tight engagement of the hub and the fluid storage container.

Abstract: An auto-injector comprising an elongate housing containing a syringe. The housing having a an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring pushing the needle from a covered position into an advanced position, operating the syringe and covering the needle. An activator arranged to lock the spring prior to manual operation and capable of, upon manual operation, releasing the spring means for injection. A first gear arrangement and a second gear arrangement arranged for converting torque from a first end and a second end of the torsion spring into a translative force. The first end groundable in the housing while the second end acts on a plunger through the second gear arrangement for advancing the needle and supplying the dose.

Abstract: Safety intravenous catheters (IVCs) are disclosed herein having a catheter hub with a catheter tube, a needle with a needle hub, and a needle guard. The needle guard is configured to be positioned at least partially within an interior space of the catheter hub and is retained thereto by mechanical engagement between the two. Following removal of the needle from the catheter hub, the needle guard is configured to disengage from the catheter hub and attach over a tip of the needle to shield the needle tip from inadvertent needlesticks. The needle guard having an angled end section configured with a length and a width to retain the needle tip within a tip holding space behind the angled end section.

Abstract: This invention provides devices and methods for insertion of a catheter into a vessel. The devices include coaxial slidably mounted needle, dilator and catheter components. The methods include piercing a vessel with the needle component, dilating the pierced hole with the dilator component, retraction of the needle component, insertion of the catheter and withdrawal of the dilator.

Abstract: An apparatus is presented comprising a lock out member configured to be implemented into a medical device, in particular a dispense interface, attachable to a second medical device, in particular a main body, wherein said lock out member is configured to prevent a second attachment of said medical device to said second medical device, wherein said lock out member has at least a first area with a first cross-sectional area, wherein said lock out member has at least a second area having a second cross-sectional area smaller than the first cross-sectional area, such that an electric resistance is defined between opposite ends of the lockout member and wherein said lock out member, at least in the second area, is made of a conductive material.

Abstract: A syringe includes a monolithic barrel (12) being divided into two bore portions, a first bore portion (22) extending from the needle adapter partially towards the second axial end and a second bore portion (24) extending from the first bore portion to the second axial end, wherein the first bore portion is circular in cross section and the second bore portion has a cross sectional shape that at least partially extends beyond the radius of the first bore portion. The syringe includes a plunger (14) sized to fit within and move along the longitudinal axis of the first bore portion. A plunger rod (16) extends along the longitudinal axis of the monolithic barrel, the plunger rod including a first array of notches and/or protuberances (30) along at least a portion of its length.

Abstract: The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152,153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201,202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201,202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.

Abstract: The present invention relates to a medicament delivery device that is reliable, safe and intuitive to use and configured to prevent a subsequent does from being administered before a previously initialized dose has been fully delivered. This is accomplished by mechanically interacting structures arranged as an interface between a lockable delivery button and a release member.

Abstract: A stopper configured to slidably move within the hollow lumen of a syringe to facilitate movement of fluid within the syringe. The stopper includes a base and one or more capture members extending rearwardly from the base. The one or more capture members each include a beveled edge configured to interact with a piston of a fluid injection apparatus, wherein the one or more capture members are radially deflected upon rotation of the stopper relative to the piston to facilitate removal of the stopper from the piston. The stopper is configured for slidable movement within a body of a syringe and forms a fluid tight seal with an inner wall of the body of the syringe. Also disclosed is a plunger which includes the stopper.

Abstract: Skin stimulus arrangements are described for creating a stimulus in the skin in the vicinity of a treatment or wound site to alleviate the perception of pain. First and second textured surfaces are provided for making contact with the skin, with the surfaces being moved to create a stimulus which alleviates the perception of pain. The movement may be linear, rotary or a combination of both, and just a single textured surface may be provided.

Abstract: A dispense interface for use with a drug delivery device with an inner body and with a lockout element. The lockout element is coupled to the inner body movable from a receptive condition to a locked condition, wherein in the receptive condition the dispense interface is attachable to the drug delivery device. In the locked condition, the dispense interface is not-attachable to the drug delivery device. The lockout element is configured to move from the receptive condition to the locked condition when said dispense interface is attached to and detached from said drug delivery device.

Abstract: An apparatus for percutaneously implanting a localization wire into a tissue mass includes a handle having a grip portion and a base. The grip portion is slidably mounted to the base. The base has a keyway. A cannula is movable relative to the handle between an insertion position and a retracted position. A localization wire is positioned to extend from the handle and into the cannula lumen. An actuator is coupled to the cannula and is configured to operate between a charged condition and a discharged condition to retract the cannula. A collar is mounted to the cannula. The collar includes a key having a key projection. The key projection is not aligned with the keyway when the actuator is in the charged condition and the key projection is aligned with the keyway to facilitate retraction of the cannula toward the retracted position to effect the discharged condition.

Abstract: A single-use needle cover configured to obscure, protect, or hide at least a portion of a needle from view before, during, and/or after an injection and/or aspiration procedure is disclosed. In some embodiments, the cover includes a housing at least partially containing the needle and configured to couple to a syringe, wherein the housing includes an axis and a guide member. In some embodiments, a sleeve has a plurality of tracks configured to slidingly receive the guide member, wherein the sleeve is configured to retract, extend, and rotate with respect to the housing. In some embodiments, after the sleeve has been retracted and extended one time, a first locking member inhibits further retraction of the sleeve and a second locking member inhibits rotation of the sleeve.

Abstract: In the joint mechanism, when connecting a plunger to a piston, after engaging members of a plunger-side engaging region in a retracted state pass through a first engaging wall region of a piston-side engaging region, the engaging members of the plunger-side engaging region come into a projected state in a second engaging wall region and the projected state of the engaging members is fastened by a fast block, and thereby, the plunger-side engaging region engages with the piston-side engaging region.

Abstract: Described is a needle safety device comprising a needle hub including a plurality of resilient arms having detents, a needle having a distal tip, and a needle shield telescopically coupled to the needle hub. The needle shield includes a plurality of axial slots adapted to engage the detents on the resilient arms and the detents are axially movable in the slots. The needle shield includes a plurality of grooves separated from the slots by separation walls and the grooves are adapted to engage the detents. When the needle shield is in a first position relative to the needle hub, the needle shield covers the distal tip of the needle and the detents are engaged in the slots. When the needle shield is in a second position relative to the needle hub, the distal tip of the needle protrudes through an aperture in the needle shield and the detents are engaged in the slots.