Material Impelled Into Body By Contraction Of Expanded Elastic Material Reservoir Patents (Class 604/132)
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Patent number: 7828770Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient.Type: GrantFiled: October 31, 2007Date of Patent: November 9, 2010Assignee: BioQuiddity, Inc.Inventors: Donald B. Bivin, Marshall S. Kriesel, Joshua W. Kriesel, Alan D. Langerud
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Patent number: 7828771Abstract: A patch pump device generally includes at least one fluid source, a fluid communicator, and an electrochemical actuator. The fluid communicator is in fluid communication with the fluid source. The electrochemical actuator is operative to cause fluid to be delivered from the fluid source into the fluid communicator.Type: GrantFiled: July 28, 2008Date of Patent: November 9, 2010Assignee: Entra Pharmaceuticals, Inc.Inventors: Yet-Ming Chiang, Michael J. Cima, J. Richard Gyory, Glenn R. Booma
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Patent number: 7815604Abstract: A device and method for the infusion of medicinal fluid at a controlled flow rate to a wound site or the blood stream of a patient is disclosed. A pump delivers fluid under pressure from a fluid source through a continuous and substantially constant flow path and through a supplemental bolus dose flow path. A large volume bolus dose reservoir accumulates a large quantity of fluid from the bolus dose flow path and holds the fluid under pressure. A flow regulator controls the fill rate of the large volume bolus reservoir. The large volume supplemental bolus dose is released from the bolus reservoir upon patient activation of a valve. The release rate of the bolus dose is controlled by the decompression of an elastomeric sphere or spring chamber, by the pressure gradient at the valve and/or by optional flow control tubing.Type: GrantFiled: December 29, 2005Date of Patent: October 19, 2010Assignee: I-Flow CorporationInventors: Roger Dillard Massengale, Kenneth W. Rake, Eric Mabry
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Publication number: 20100262077Abstract: A microfluidic device is provided for delivering a drug to an individual. The microfluidic device includes a body that defines a reservoir for receiving the drug therein. A valve interconnects the reservoir to an output needle that is insertable into the skin of an individual. A pressure source urges the drug from the reservoir toward the needle. The valve is movable between a closed position preventing the flow of the drug from the reservoir to the output needle and an open position allowing for the flow of the drug from the reservoir to the output needle in response to a predetermined condition in the physiological fluids of the individual.Type: ApplicationFiled: June 23, 2010Publication date: October 14, 2010Inventors: David J. Beebe, Michael J. MacDonald, David T. Eddington, Glennys A. Mensing
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Patent number: 7806865Abstract: A pressurized infusion device has a flexible band with first and second ends, a curved base, and a bag containing fluid. The bag is located between the flexible band and the curved base. The second end of the flexible band is coupled to a shaft. A motor is also coupled to the shaft. The motor is actuated to turn the shaft and produce tension in the band thereby changing the fluid pressure in the bag.Type: GrantFiled: May 20, 2009Date of Patent: October 5, 2010Assignee: Alcon Research, Ltd.Inventor: Daniel J. Wilson
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Publication number: 20100241074Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient.Type: ApplicationFiled: May 28, 2010Publication date: September 23, 2010Inventors: Donald B. Bivin, Marshall S. Kriesel, Joshua W. Kriesel, Alan D. Langerud
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Publication number: 20100241060Abstract: Surgical devices and methods are described. The devices are for implanting fluidic material in a patient's eye and comprise a nozzle and a housing having a slide and a bellows. The bellows is adapted to undergo compression or decompression. The surgical procedures make use of the surgical devices and include a tissue translocation surgical procedure, a retinal implantation surgical procedure, and a corneal transplantation surgical procedure.Type: ApplicationFiled: March 18, 2009Publication date: September 23, 2010Inventors: Keith ROIZMAN, H. Michael Lambert, Patrick Michael Elliott
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Publication number: 20100222741Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient.Type: ApplicationFiled: May 3, 2010Publication date: September 2, 2010Inventors: Donald B. Bivin, Marshall S. Kriesel, Joshua W. Kriesel, Alan D. Langerud
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Patent number: 7753884Abstract: An apparatus is proposed for the dosed dispensing of a fluid, especially an infusion fluid, comprising a housing (1) with a fluid chamber and a pressure medium chamber (3) by which a flexible wall (4) of the fluid chamber can be pressurized from the outside with a pressure medium. In order to provide a re-useable infusion pump with especially simple means it is proposed that the housing (1) consists of two mutually detachably joined housing parts (6, 7), of which the one comprises the pressure medium chamber (3) and the other receives in an exchangeable manner the fluid chamber configured as a leak-proof infusion bag (2), and that the housing part (6) with the pressure medium chamber (3) is sealed by a membrane (5) against the housing part (7) receiving the infusion bag (2) and is connected to a gas pressure source (11).Type: GrantFiled: August 3, 2004Date of Patent: July 13, 2010Assignee: PRO-MED Medizinische Produktions- und Handels-AGInventor: Bernhard Gallnböck
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Publication number: 20100145274Abstract: Rendering conspicuous liquid medicaments which are conventionally supplied as colorless liquids. A coloring agent may be added to the conventionally colorless liquid. Where different liquid medicaments are supplied, coloring agents of different hues may be added to the respective different liquid medicaments. A syringe for dispensing liquids may be provided with a temperature responsive device which changes in appearance so as to indicate level of liquid medicament loaded thereinto, responsively to temperature of the liquid medicament.Type: ApplicationFiled: December 10, 2008Publication date: June 10, 2010Inventor: Jan Royce
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Publication number: 20100137808Abstract: A cartridge assembly apparatus for an auto-injector includes a flexible container containing a liquid medicant. A needle hub is connected to the flexible container. A needle is attached to the needle hub and extends proximally from the needle hub. A frame is connected to the needle hub and includes a frame proximal end extending proximally beyond a proximal end of the needle. The needle hub and the needle are displaceable relative to the frame in a proximal direction to insert the needle into a patient.Type: ApplicationFiled: November 24, 2009Publication date: June 3, 2010Applicant: MERIDIAN MEDICAL TECHNOLOGIES, INC.Inventors: John G. Wilmot, Clarence M. Mesa, Robert L. Hill, James R. Stewart, JR., Colin J. Mathews, Chris J. Hurlstone, Ben G. Turner, Christian Dunning
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Patent number: 7725272Abstract: Methods and devices are described for monitoring reservoir fluid in an implantable infusion pump. Such methods and devices can be used when the infusion pump has a temperature-dependent component. For example, a method of monitoring reservoir fluid can include obtaining measurements from the reservoir that include corresponding data related to the amount of fluid and temperature in the reservoir. A pair of measurements can be used to monitor the fluid level, or flow rate out of, the reservoir when the corresponding temperatures of the measurements are within a temperature tolerance value. In such an instance, a measured amount difference can be calculated based on the fluid amounts corresponding to the pair of measurements. Other variations of fluid monitoring methods, and implantable infusion pump systems that can perform fluid monitoring, are also described.Type: GrantFiled: March 30, 2006Date of Patent: May 25, 2010Assignee: Codman Neuro Sciences, SARLInventors: Alec Ginggen, Rocco Crivelli
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Patent number: 7704230Abstract: A fluid reservoir for a medical infusion system includes an expandable elastomeric bladder defining a chamber for receiving and containing a volume of therapeutic substance and exerting pressure thereon to dispense the therapeutic substance from the bladder. The bladder has preferably a single port formed through the thickness thereof. A bi-directional valve is in fluid communication with the chamber of the elastomeric bladder and is used for filling the bladder chamber with the therapeutic substance and for connecting to a catheter assembly for dispensing the therapeutic substance to a patient undergoing treatment. The single port of the elastomeric bladder is connected to a medical grade flexible tubing, which is also connected to the bi-directional valve.Type: GrantFiled: December 29, 2005Date of Patent: April 27, 2010Assignee: Ethicon, Inc.Inventors: Etan Chatlynne, Steven Nguyen, Frank Cichocki, David Lindh
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Publication number: 20100094218Abstract: A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.Type: ApplicationFiled: October 15, 2008Publication date: April 15, 2010Inventors: Marshall S. Kriesel, Joshua W. Kriesel, Thomas N. Thompson
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Patent number: 7686788Abstract: A catheter having a drug delivery unit at the distal end thereof. The drug delivery unit includes an actuator capable of assuming an activated and an inactivated configuration. The drug delivery unit also includes a receptacle capable of accepting a therapeutic agent. The actuator and receptacle are in communication with each other such that the actuator transmits force to the receptacle and the receptacle accepts force from the actuator in an activated configuration of the actuator. Also provided is a method of delivering a therapeutic agent to a target site using the catheter of the present invention.Type: GrantFiled: March 3, 2005Date of Patent: March 30, 2010Assignee: Boston Scientific Scimed, Inc.Inventors: Toby Freyman, Maria Palasis, Wendy Naimark, Timothy J. Mickley
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Publication number: 20100069830Abstract: Methods and compact automatic devices are provided for delivery of micro doses of liquid drugs to a patient. Devices have a fluid supply reservoir comprising an expandable indicator supplied with a sensor, a mechanism forcing the fluid to squeeze predetermined dose out, and a processor treating sensor's signals accordingly to preprogrammed algorithm. The method comprises steps: (a) initiating the delivery cycle, (b) acquiring sensor's signals, (c) treating signals in order to integrate an intensity of output flow and to determine when the squeezing-out force must be terminated, (d) terminating the cycle accordingly to processor's command. Self-testing of devices occurs while each fluid delivery cycle. Their high dosing precision exceeds that of known analogs about two orders of magnitude. A possibility to use low cost disposable exit port assembly and/or easy replaceable factory pre-filled cartridges is an additional advantage eliminating risks of overdosing, air bubbles, and/or compromised sterility.Type: ApplicationFiled: September 14, 2009Publication date: March 18, 2010Inventor: Leonid Grigorov
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Patent number: 7678079Abstract: A system and method for a patch-like, self-contained substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir subassembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. Simple removal of an interlock allows a disk, or Belleville spring assembly to apply an essentially even and constant pressure to the contents of the fluid reservoir assembly, and allows the device to then be attached to a skin surface via an adhesive contact surface. A push button activation assembly is provided which can then be used to release and seat one or more spring-loaded patient needles into the skin surface, and establish a fluid communication path between the patient needles and the pressurized fluid reservoir contents thereby delivering an infusion into the skin.Type: GrantFiled: April 25, 2007Date of Patent: March 16, 2010Assignee: Becton, Dickinson and CompanyInventors: Charles D. Shermer, Kenneth G. Powell, Alexander G. Lastovich, P. Spencer Kinsey, Chad C. Smutney, John M. Polidoro, Ed Browka, Carl R. Sahi, James K. Fentress, David S. Chapin, Daniel Stipe, Jeff M. Moss, Melody Kuroda
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Patent number: 7654982Abstract: An infusion pump and method are provided which control flow rates with variable fluid pressure and variable series flow resistance.Type: GrantFiled: February 27, 2007Date of Patent: February 2, 2010Assignee: Fluidnet CorporationInventors: Jeffrey A. Carlisle, Lawrence M. Kuba, John M. Kirkman, Jr.
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Publication number: 20090312742Abstract: Embodiments of an implantable electrolytic pump include a first expandable diaphragm and a second flexible diaphragm, and first and second chambers each for containing a fluid, wherein the first expandable diaphragm separates the first and second chambers and provides a fluid barrier therebetween, and the second chamber is formed between the first expandable diaphragm and the second flexible diaphragms. The pump may further include electrolysis electrodes within the first chamber for causing generation of a gas therein and to thereby expand the expandable diaphragm so that fluid is forced from the second chamber into a cannula.Type: ApplicationFiled: May 8, 2009Publication date: December 17, 2009Inventors: Changlin Pang, Fukang Jiang, Jason Shih, Sean Caffey, Mark Humayun, Yu-Chong Tai
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Publication number: 20090306593Abstract: The invention relates to a mechanically operated liquid pump (1), particularly for medical or nutrition-physiological liquids, with a housing (2) and with an expandable clastic element (16), which is held therein and which serves to store and deliver the liquid, and with a closeable access (21) and exit (50) for the liquid from the elastic element as well as with a device for largely constantly maintaining or limiting the liquid volume flow discharged by the elastic element. According to the invention, the following features are provided: the elastic element is provided in the form of a balloon (16) that has an opening (17a); a core (11) is housed inside the housing and is inserted into the balloon via the opening; means (20) for fastening and sealing the balloon in the area of its end having the opening are provided on the core or on the housing, and; when relatively unstressed, the balloon rests against the core at a distance from its fastening.Type: ApplicationFiled: July 21, 2006Publication date: December 10, 2009Inventors: Roland Wex, Harald Hansmann, Christian Kenzler
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Publication number: 20090281494Abstract: Ambulatory infusion devices with components that may be heat sterilized.Type: ApplicationFiled: May 6, 2008Publication date: November 12, 2009Inventor: Stephen D. Das
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Publication number: 20090247950Abstract: A continuous drug solution infusion device is provided that is capable of administering a drug solution into a patient's body for a predetermined period of time substantially at a predetermined flow rate from the beginning to end of the drug solution infusion by suppressing the change in pressure from the beginning to end of the infusion. The continuous drug solution infusion device has at least two tubular members disposed in series along an infusion path for a drug solution and at least one expandable/contractible tubular member disposed between the tubular members.Type: ApplicationFiled: July 11, 2006Publication date: October 1, 2009Inventors: Osamu Tsukada, Yasuhiko Nakajima
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Patent number: 7563255Abstract: The invention provides a miniaturized, implantable drug delivery device and a method of delivering over a prolonged period of time one or more drugs using such a device. The drug delivery device can be adapted for attachment to the outer surface of an eye. Once attached to the outer surface of an eye, the device can deliver one or more drugs directly into the eye for preventing or ameliorating the symptoms of a particular ocular disorder.Type: GrantFiled: May 2, 2002Date of Patent: July 21, 2009Assignees: Massachusetts Eye and Ear Infirmary, The Charles Stark Draper Laboratory Inc.Inventors: Anthony P. Adamis, Joan W. Miller, Evangelos S. Gragoudas, Mark J. Mescher, Christopher E. Dubé, Jeffrey T. Borenstein, Marcie G. Weinstein, Raanan A. Miller, Mitchell L. Hansberry
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Patent number: 7530968Abstract: Presently disclosed is a hydraulic pump device and use thereof, especially in a fluid delivery system. In one embodiment, the fluid delivery system is an inexpensive, single-use device for slow dosing medicament applications. The fluid delivery system may employ a spring-compressed bellows crank or other combination of simple mechanisms operating according to the well-known peristaltic principle to force a volume of ultrapure bio-inert hydraulic fluid through an aperture, thereby expanding one chamber of a two chamber hydraulic cylinder. The second, fluid storage chamber, containing the medicament, is emptied through a conventional orifice in response to the expansion of the pump chamber. The medicament may thence flow through any suitable infusion set into a patient removeably attached thereto.Type: GrantFiled: April 23, 2004Date of Patent: May 12, 2009Assignee: Valeritas, Inc.Inventor: Robert R. Gonnelli
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Publication number: 20090112163Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient.Type: ApplicationFiled: October 31, 2007Publication date: April 30, 2009Inventors: Donald B. Bivin, Marshall S. Kriesel, Joshua W. Kriesel, Alan D. Langerud
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Patent number: 7520868Abstract: A medical fluid delivery apparatus for the discharge of a specific and constant volume of medical fluids includes a two-layered tubular body that is wound on a projecting holder, which reduces the change in expansion pressure. Having the tubular body wound up enables a variety in design. The utilization of an intermediate ring enables a variety of products just by exchanging the intermediate ring to provide different capacity volumes of the tubular body.Type: GrantFiled: April 12, 2004Date of Patent: April 21, 2009Assignee: Acemedical Co., Ltd.Inventor: Jong Woo Lee
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Patent number: 7517335Abstract: An infusion device for continuous infusion of medication is disclosed, in which infusion is controlled over two separate fluid communications. The infusion is in each fluid communication controlled by restricting means and valve means, and one of the fluid communications farther contains a holding device for bolus rate of infusion for a short period. The device comprises a flow regulating device comprising a passage defined by at least a first element and a second element, wherein at least one of the first and second element is a primary deformable element adapted to be elastically deformed so as to change the cross sectional area of the passage. Furthermore the device comprises a container for storage and supply of a medication in fluid form, said container comprising a first and a second chamber being arranged relatively to each other so that when volume of the first chamber Increases the volume of the second chamber decreases.Type: GrantFiled: February 18, 2003Date of Patent: April 14, 2009Assignee: CeQur ApSInventors: Peter Gravesen, Per Brandt Rasmussen, Holger Dirac
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Publication number: 20090082727Abstract: A mechanical operated injection device which has the size of a credit card. The very compact size is obtained by using a flexible reservoir (90) containing the drug to be delivered and a suction pump (60, 70, 80) for pumping the liquid drug from the flexible reservoir to the body of the user. The pump is driven in cycles by a spring assembly which is energized by the user when setting the dose to be injected. The injection device is further connected to a needle assembly by a snap mechanism only requiring a 90 degree rotation of the injection needle assembly in order to release the injection needle assembly from the injection device.Type: ApplicationFiled: June 27, 2005Publication date: March 26, 2009Applicant: Novo Nordisk A/SInventors: Claus Schmidt Moeller, Thomas Dedenroth Miller
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Patent number: 7410476Abstract: A device for delivering a substance into the skin of a patient includes a body and a skin penetrating device having at least one skin penetrating member, such as a microneedle. The body includes an internal cavity and a device for indicating the delivery of a sufficient amount of the substance to the patient and for producing a dispensing pressure to dispense and deliver the substance from the cavity. The indicating device is visible from the exterior of the delivery device. In some embodiments, the indicating device is an elastic expandable diaphragm which, when the cavity is filled with a substance, creates the dispensing pressure.Type: GrantFiled: July 8, 2005Date of Patent: August 12, 2008Assignee: Becton, Dickinson and CompanyInventors: Bradley M. Wilkinson, Mark Newby
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Publication number: 20080183135Abstract: An infusion apparatus including a support member and an elastic sleeve surrounding the support member to define a fluid reservoir therebetween. The sleeve is expandable in a radial direction when the infusion apparatus is loaded with a fluid, such as a pain medication, and exerts a pressure on the fluid so that it may be delivered to a desired site, such as a surgical region of a patient. The elastic sleeve is sealed to the support member at spaced-apart locations by first and second sealing arrangements. Each sealing arrangement preferably includes a sealing member having a first end, a second end, and a body portion extending between the first and second ends. Desirably, the body portion is substantially annular in shape and is deflectable between a first inner diameter and a second inner diameter.Type: ApplicationFiled: January 28, 2008Publication date: July 31, 2008Applicant: I-FLOW CorporationInventor: Kevin M. Forrest
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Patent number: 7374556Abstract: A fluid dispensing system provides a non-contact method of monitoring the change in the fluid volume over time. This approach avoids the use of probes or sensors that come into direct contact with the fluid to be dispensed. The system comprises an apparatus comprising three chambers. The first chamber has a fixed volume and contains a pressurized gas. A solenoid valve is used to control the flow of gas from the first chamber into the second. The second chamber is sealed so that the combined mass of air in the first and second chambers remains fixed. The third chamber is adjacent to the second and contains medication in the form of incompressible fluid that is to be administered to a human or animal subject via a suitable delivery port. A piston is disposed between the second and third chambers and is movable responsive to the flow of gas into the second chamber to dispense fluid from the third chamber as desired.Type: GrantFiled: January 31, 2006Date of Patent: May 20, 2008Assignee: Tandem Diabetes CareInventor: Scott Mallett
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Publication number: 20080097321Abstract: A system includes a durable portion with a durable housing and a separable disposable portion with a disposable housing that selectively engage with and disengage from each other. The disposable housing secures to a patient and may be disposed of after it has been in use for a prescribed period. Components that normally come into contact with a patient or with an infusion medium may be part of the disposable portion to allow for disposal after a prescribed use. A reservoir for holding the infusion medium may be part of the disposable portion, and may be supported by the disposable housing. The durable portion may include other components such as electronics for controlling delivery of the infusion medium from the reservoir, and a drive device including a motor and drive linkage.Type: ApplicationFiled: November 20, 2006Publication date: April 24, 2008Inventors: R. Paul Mounce, Julian D. Kavazov
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Publication number: 20080058718Abstract: A wearable infusion device delivers a liquid medicant to a patient. The infusion device comprises a base that contacts a patient's skin and a reservoir arranged to be filled with a liquid medicant to be delivered beneath a patient's skin. The reservoir has an outlet through which the medicant flows. The infusion device further comprises a flexible conduit communicating with the outlet of the reservoir, a pump that causes the medicant to flow down the conduit, an actuator that performs a function related to the operation of the device, and an enable mechanism that enables the actuator in response to the filling of the reservoir with the liquid medicant.Type: ApplicationFiled: September 6, 2006Publication date: March 6, 2008Inventors: John M. Adams, Clifton A. Alferness, Daniel Hawkins
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Publication number: 20080027376Abstract: A dispensing device for dispensing medicaments to a patient which includes a supporting structure; a carriage assembly interconnected with the supporting structure for movement between a first position and a second position and a semi-rigid, collapsible reservoir carried by the carriage assembly. A stored energy source is operably associated with the carriage assembly for moving the carriage assembly between the first and second positions. The device also includes novel structure, including fill-vials, for adding medicaments to the fluid within the fluid reservoir.Type: ApplicationFiled: June 25, 2007Publication date: January 31, 2008Inventors: Marshall S. Kriesel, Joshua W. Kriesel
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Publication number: 20080027386Abstract: A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as analgesics and like medicinal agents from the device reservoir which is provided in the form of a novel bellows-type assembly. The fluid dispenser includes a unique stored energy mechanism that provides the force necessary to continuously and substantially uniformly expel fluid from the device reservoir. The device also includes a novel adjustable flow rate control assembly that is disposed intermediate the fluid reservoir outlet and the outlet port of the device for precisely controlling the rate of fluid flow from the outlet port toward the patient.Type: ApplicationFiled: July 31, 2007Publication date: January 31, 2008Inventors: Joshua W. Kriesel, Marshall S. Kriesel, Thomas N. Thompson
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Patent number: 7322961Abstract: An infusion apparatus including a support member and an elastic sleeve surrounding the support member to define a fluid reservoir therebetween. The sleeve is expandable in a radial direction when the infusion apparatus is loaded with a fluid, such as a pain medication, and exerts a pressure on the fluid so that it may be delivered to a desired site, such as a surgical region of a patient. The elastic sleeve is sealed to the support member at spaced-apart locations by first and second sealing arrangements. Each sealing arrangement preferably includes a sealing member having a first end, a second end, and a body portion extending between the first and second ends. Desirably, the body portion is substantially annular in shape and is deflectable between a first inner diameter and a second inner diameter.Type: GrantFiled: January 15, 2003Date of Patent: January 29, 2008Assignee: I-Flow CorporationInventor: Kevin M. Forrest
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Publication number: 20080004570Abstract: A collagen delivery device is disclosed and can include a barrel having a syringe chamber. Further, a syringe can be disposed within the syringe chamber. The syringe can include a collagen material therein. Additionally, the collagen delivery device can include a plunger within the barrel. The plunger can be moved to expel the collagen material from the syringe.Type: ApplicationFiled: June 30, 2006Publication date: January 3, 2008Applicant: WARSAW ORTHOPEDIC, INC.Inventors: Thomas A. Simonton, Jeffrey M. Gross, Sean M. Haddock, Hai H. Trieu
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Publication number: 20070270749Abstract: A by-pass control system for a meat injection system has a variable speed pump that transports fluid to a meat injection machine. Excess fluid is transported to a by-pass control valve. The valve has a moveable piston disposed therein that separates the valve into a fluid chamber and an air chamber. The piston moves back and forth based on the relationship between fluid pressure and air pressure. Sensors are disposed within or through the lid or the valve to sense the position of the piston. A controller is connected to the sensors and the variable speed pump and adjusts the speed of the pump based on the position of the piston.Type: ApplicationFiled: May 19, 2006Publication date: November 22, 2007Applicant: STORK TOWNSEND INC.Inventors: Daniel W. PFEFFER, Michael S. SIMPSON, Craig A. SMIENS
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Patent number: 7270647Abstract: A system and method to administer a liquid agent into a body cavity of a patient is provided. One exemplary system comprises a lumen disposed into an airway of the patient and a valve assembly coupled to the lumen. The valve assembly comprises a body portion, a first port and a second port. A pump assembly for receiving the liquid agent is coupled to the valve assembly in a fluid tight relationship. The pump assembly provides the liquid to the lumen through the first port of the valve assembly. The liquid along with a portion of secretions generated by the patient are extracted through the lumen and flow out of said valve assembly through the second port for disposal responsive to a natural body function and/or a vacuum from a vacuum source.Type: GrantFiled: March 3, 2005Date of Patent: September 18, 2007Assignee: Boehringer Technologies, L.P.Inventors: John Karpowicz, Kevin P Klocek
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Patent number: 7144385Abstract: For safely inserting a catheter into a chest cavity of a child or corpulent patient to be retained therein and for preventing atmospheric air from proceeding into the chest cavity during a removal of a penetrating needle, discharge equipment for medical procedures is provided which equipment includes a connector cap and a storage bottle detachably connectable to each other, a connector to be connected to the catheter retained in the patient, a check valve including an outer periphery covered by a protective cover and being openable only toward a storage bottle side, and a coupling device to the storage bottle mounted on the connector cap. The storage bottle is a hollow container including an inlet port and a discharge port, a detachably connecting device for the connector cap mounted on the inlet port, and a check valve openable only toward an exterior of the storage bottle is mounted on the discharge port.Type: GrantFiled: June 18, 2002Date of Patent: December 5, 2006Assignee: Sumitomo Bakelite Company LimitedInventors: Yoshifumi Matsuura, Tomohiro Isono, Yukihiko Sakaguchi
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Patent number: 7087035Abstract: A device and method for enhancing skin piercing by microprotrusions involves pre-stretching the skin to enhance pathway formation when the microprotrusions are pressed into the skin. An expandable device includes skin engaging opposite ends that contact the skin surface so that when the device is expanded the skin is stretched. The skin is placed under a tension of about 0.01 to about 10 megapascals, preferably about 0.05 to 2 megapascals. The device has a plurality of microprotrusions which penetrate the skin while the skin is being stretched by the expanded device. Another stretching device employs suction for skin stretching.Type: GrantFiled: December 8, 2000Date of Patent: August 8, 2006Assignee: Alza CorporationInventors: Joseph C. Trautman, Michel J. N. Cormier, Kellee Eng, Wei-Qi Lin, Hyunok L. Kim, Sara L. Sendelbeck, Armand P. Neukermans, Bruce P. Edwards, Wai-Loong Lim, Andrew I. Poutiatine, J. Richard Gyory
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Patent number: 7008403Abstract: A fluid dispensing system provides a non-contact method of monitoring the change in the fluid volume over time. This approach avoids the use of probes or sensors that come into direct contact with the fluid to be dispensed. The system comprises an apparatus comprising three chambers. The first chamber has a fixed volume and contains a pressurized gas. A solenoid valve is used to control the flow of gas from the first chamber into the second. The second chamber is sealed so that the combined mass of air in the first and second chambers remains fixed. The third chamber is adjacent to the second and contains medication in the form of incompressible fluid that is to be administered to a human or animal subject via a suitable delivery port. A piston is disposed between the second and third chambers and is movable responsive to the flow of gas into the second chamber to dispense fluid from the third chamber as desired.Type: GrantFiled: July 19, 2002Date of Patent: March 7, 2006Assignee: Cognitive Ventures CorporationInventor: Scott Mallett
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Patent number: 6979316Abstract: An auto-injector for rapid delivery of a bolus of injectable medication has a generally flat, sealed housing with small peripheral dimensions, approximating those of a credit card. A syringe, configured to be contained within the flat housing is pre-filled with the medication. The housing contains a mechanism that, when triggered, automatically drives the syringe and needle forwardly to an injection position and then continues to compress the volume of the syringe to effect rapid injection. The forward injection end of the device includes an actuator that also conceals and protects the needle at all times and, prevents post-injection hazards. The flat faces of the device have graphic symbols and other visual indicia relating to the operation and condition of the device. The device enables a simple three-step operation that reduces the risk of improper use.Type: GrantFiled: May 23, 2002Date of Patent: December 27, 2005Assignee: Seedlings Life Science Ventures LLCInventors: Keith H. Rubin, James M. Sellers, Haydn B. Taylor
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Patent number: 6905479Abstract: The present invention involves, in some embodiments, reusable pump drive systems, which are coupled to removable, and preferably disposable, pumping cartridges. The invention provides, in some embodiments, novel pumping cartridges for use in pumping systems. One such cartridge includes an integrated filter element therein for filtering fluids, for example fluids pumped to the body of a patient in a medical procedure. In some embodiments, the integrated filter is utilized as a blood clot removal filter and in other embodiments is used to remove particulates liquids infused to a patient. The filter element includes a filter with pores therein that are preferably sized to permit essentially unrestricted flow of individual human blood cells therethrough and to block or collect blood clots, cell clumps, particulates etc. with sizes substantially larger than the average size of a human blood cell.Type: GrantFiled: July 20, 1999Date of Patent: June 14, 2005Assignee: Deka Products Limited PartnershipInventors: Clement D. Bouchard, Lawrence B. Gray
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Patent number: 6892755Abstract: An improved ambulatory infusion device for dispensing a fluid into a patient includes a flexible bladder enclosure having a first open end a closed second end. The closed second end of the sheath is free to conform to the body of the patient so that the device is comfortable when worn. In other aspects, a pressure regulator of the device is adapted to maintain the outlet pressure within a predetermined range of pressures so that the fluid flow rate is substantially constant during fluid flow. A flow restrictor of the device is formed of flexible tubing. An ambulatory infusion device for dispensing a fluid at a predetermined fluid flow rate includes an elastic bladder having an interior volume for storing the fluid under pressure and an opening for dispensing the fluid. A pressure regulator is in fluid communication with the opening of the bladder and includes an inlet for receiving fluid from the bladder at an inlet pressure and an outlet for discharging the fluid at a predetermined outlet pressure.Type: GrantFiled: February 28, 2003Date of Patent: May 17, 2005Assignee: Baxter International Inc.Inventor: Larry Black
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Patent number: 6878133Abstract: A delivery apparatus for pressurized medical liquids has a primary reservoir and a primary pressurizing arrangement configured for removably pressurizing medical liquid in the primary reservoir to a delivery pressure. A secondary reservoir has an inlet connected via a valve to receive pressurized liquid from the primary reservoir. As secondary pressurizing arrangement is arranged for supplying a compensating pressure to the received pressurized liquid to maintain it at substantially the delivery pressure as pressure is reduced in the primary reservoir, particularly during refilling with medical liquid from an unpressurized source.Type: GrantFiled: September 10, 2002Date of Patent: April 12, 2005Assignee: Maquet Critical Care ABInventors: Christer Ahlmen, Petter Videbrink
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Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners
Patent number: 6835194Abstract: The invention features devices and methods for treatment of pain. The drug delivery device is a drug delivery system adapted for whole implantation in a subject and to provide pain relief by delivery of fentanyl or a fentanyl congener (e.g., sufentanil) over a protracted period of time (e.g., at least 3 days or more than 3 days). The device comprises a housing defining a reservoir that contains a drug formulation, a pump operatively connected to the housing so as to facilitate movement of drug out of the reservoir and out of the device, and a thermal expansion element which defines a flow pathway comprising a thermal expansion channel to accommodate thermal expansion of formulation in the reservoir. The device can further comprise a valve positioned within the flow pathway so as to prevent movement of drug out of the reservoir prior to use.Type: GrantFiled: June 27, 2002Date of Patent: December 28, 2004Assignee: Durect CorporationInventors: Randolph Mellus Johnson, Felix Theeuwes, Edward M. Gillis, Dana Litmanovitz, Barbara Laidlaw, James Brown, John Culwell, James A. Filice, Peter Wickman, Su-Il Yum, Andrew Poutiatine, John Dinka -
Publication number: 20040171987Abstract: An improved ambulatory infusion device for dispensing a fluid into a patient includes a flexible bladder enclosure including a sheath of flexible material having a first open end a closed second end. The first open end of the sheath is affixed to a rigid closure, and a bladder support is secured in fixed position relative to the closure. An elastic bladder is mounted on the bladder support and positioned inside the sheath for holding fluid to be dispensed. The closed second end of the sheath is free to conform to the body of the patient so that the device is comfortable when worn. In other aspects, a flow restrictor and a pressure regulator are provided.Type: ApplicationFiled: February 28, 2003Publication date: September 2, 2004Applicant: Baxter International Inc.Inventors: Mark Bridle, Larry Black
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Patent number: 6768425Abstract: A system for providing medical treatment to a patient, including a medical treatment apparatus and a remote control device. The medical treatment apparatus has a local processor, and a local communication element connected to the local processor, while the remote control device includes a remote processor, user interface components connected to the remote processor, and a remote communication element connected to the remote processor and adapted to communicate with the local communication element of the medical treatment apparatus in a wireless manner such that information can be transferred between the local processor and the remote processor. The remote control device also includes at least two separate power supplies connected to the remote processor.Type: GrantFiled: December 21, 2001Date of Patent: July 27, 2004Assignee: Insulet CorporationInventors: J. Christopher Flaherty, John T. Garibotto
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Patent number: 6767337Abstract: The invention relates to an infusion apparatus for use in combination with an infusion bag (10) comprising and/or being connectable with a conduit means (12) for transport of infusion liquid to a patient. The infusion apparatus comprises a first space (14) in which the infusion bag (10) is disposed. The infusion apparatus comprises also a second space (16). The volume of this second space (16) can be varied by supplying a pressure generating liquid to the second space (16). This change in volume of the second space (16) exerts a pressure on the infusion bag (10). The infusion apparatus comprises also a closing means (20) which exerts a load on the conduit means (12). If the pressure generating liquid exerts a pressure on the infusion bag (10) the load will decrease. This allows infusion liquid to leave the infusion bag (10) via the conduit means (12).Type: GrantFiled: August 13, 2002Date of Patent: July 27, 2004Assignee: Gepro Produktutveckling ABInventor: Göran Ewerlöf